Affiliation: Ariadne Genomics
- Binding properties and evolution of homodimers in protein-protein interaction networksIaroslav Ispolatov
Ariadne Genomics Inc 9700 Great Seneca Highway, Suite 113, Rockville, MD 20850, USA
Nucleic Acids Res 33:3629-35. 2005..We finally discuss possible implications of our empirical observations from functional and evolutionary standpoints...
- Detection of the dominant direction of information flow and feedback links in densely interconnected regulatory networksIaroslav Ispolatov
Ariadne Inc, 9430 Key West Ave, Suite 113 Rockville, MD 20850, USA
BMC Bioinformatics 9:424. 2008..The exact solution of this problem requires enumeration of all cycles and combinations of removed links, which, as an NP-hard problem, is computationally prohibitive even for modest-size networks...
- Automatic extraction of gene ontology annotation and its correlation with clusters in protein networksNikolai Daraselia
Ariadne Genomics, Inc, Rockville, MD 20850, USA
BMC Bioinformatics 8:243. 2007..In addition to having the general biological significance, such demonstration would further validate the data extraction and processing methods used to compose protein annotation and protein-protein interactions datasets...