Research Topics
| F R CollartSummaryAffiliation: Argonne National Laboratory Country: USA Publications
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Detail Information
Publications
Predicted Relative Metabolomic Turnover (PRMT): determining metabolic turnover from a coastal marine metagenomic datasetPeter E Larsen
Argonne National Laboratory, 9700, S, Cass Ave, Argonne, Illinois, USA
Microb Inform Exp 1:4. 2011..abstract:..
Using next generation transcriptome sequencing to predict an ectomycorrhizal metabolomePeter E Larsen
Biosciences Division, Argonne National Laboratory, Lemont, IL 60490, USA
BMC Syst Biol 5:70. 2011..Understanding this symbiotic relationship at a molecular level provides important contributions to the understanding of forest ecosystems and global carbon cycling...
Environment sensing and response mediated by ABC transportersSarah E Giuliani
Biosciences Division, Argonne National Laboratory, Lemont, IL 60490, USA
BMC Genomics 12:S8. 2011....
Characteristics and crystal structure of bacterial inosine-5'-monophosphate dehydrogenaseR Zhang
Center for Mechanistic Biology and Biotechnology, Argonne National Laboratory, 9700 South Cass Avenue, Argonne, Illinois 60439 4833, USA
Biochemistry 38:4691-700. 1999..Comparison of the structure of bacterial IMPDH with the known partial structures from eukaryotic organisms will provide an explanation of their distinct properties and contribute to the design of specific bacterial IMPDH inhibitors...
Bacterial expression strategies for human angiogenesis proteinsL J Dieckman
Biosciences Research Division, Argonne National Laboratory, Argonne, IL 60439, USA
J Struct Funct Genomics 7:23-30. 2006..These results validate the utility of a bioinformatically driven high throughput approach to increase the number of soluble proteins or protein domains which can be used for multiple downstream applications...
Cloning, characterization and sequence comparison of the gene coding for IMP dehydrogenase from Pyrococcus furiosusF R Collart
Center for Mechanistic Biology and Biotechnology, Argonne National Laboratory, IL 60439, USA
Gene 174:209-16. 1996..The phylogenetic analysis indicates that a gene duplication occurred prior to the division between rodents and humans, accounting for the Type I and II isoforms identified in mice and humans...
Efficient recognition of protein fold at low sequence identity by conservative application of Psi-BLAST: applicationF J Stevens
Biosciences Division, Argonne National Laboratory, Argonne, IL 60439, USA
J Mol Recognit 18:150-7. 2005..This approach significantly expands the utility of existing sequence data to define the primary structure degeneracy of binding sites for substrates, cofactors and other proteins...
Genome-scale expression of proteins from Bacillus subtilisS Moy
Biosciences Division, Argonne National Laboratory, Argonne, IL 60439, USA
J Struct Funct Genomics 5:103-9. 2004..The continued development of new technologies that can be implemented in an automated format will be essential for continued success in the structural genomic programs...
Differential signatures of bacterial and mammalian IMP dehydrogenase enzymesR Zhang
Biosciences Division, Argonne National Laboratory
Curr Med Chem 6:537-43. 1999..Elucidation of the basis for this mammalian/bacterial IMPDH signature will provide insight into the catalytic mechanism of this enzyme and the foundation for the development of highly specific inhibitors...
Express primer tool for high-throughput gene cloning and expressionJ R Yoon
Argonne National Laboratory, Argonne, IL, USA
Biotechniques 33:1328-33. 2002....
Cloning and sequence analysis of the human and Chinese hamster inosine-5'-monophosphate dehydrogenase cDNAsF R Collart
Biological, Environmental, and Medical Research Division, Argonne National Laboratory, Illinois 60439 4833
J Biol Chem 263:15769-72. 1988..Comparison of the protein sequences deduced from the human and Chinese hamster cDNA clones indicates only eight amino acid differences, suggesting that IMP dehydrogenase is a highly conserved protein...
A protein containing the cystic fibrosis antigen is an inhibitor of protein kinasesS Murao
Division of Biological, Environmental and Medical Research, Argonne National Laboratory, Illinois 60439 4833
J Biol Chem 264:8356-60. 1989....
Recombinant human inosine monophosphate dehydrogenase type I and type II proteins. Purification and characterization of inhibitor bindingP W Hager
Department of Pharmacology, University of North Carolina at Chapel Hill 27514, USA
Biochem Pharmacol 49:1323-9. 1995..Thus, MMP is a potent, tight-binding competitive inhibitor that does not discriminate between the two IMPDH isozymes...
Increased inosine-5'-phosphate dehydrogenase gene expression in solid tumor tissues and tumor cell linesF R Collart
Biological and Medical Research Division, Argonne National Laboratory, Illinois 60439
Cancer Res 52:5826-8. 1992..These results are consistent with an association between increased IMP dehydrogenase expression and either enhanced cell proliferation or malignant transformation...
