Yu Liang

Summary

Affiliation: Applied Biosystems
Country: USA

Publications

  1. ncbi Characterization of microRNA expression levels and their biological correlates in human cancer cell lines
    Arti Gaur
    Norris Cotton Cancer Center, Dartmouth Medical School, Lebanon, New Hampshire 03755, USA
    Cancer Res 67:2456-68. 2007
  2. ncbi A quantitative PCR method to detect blood microRNAs associated with tumorigenesis in transgenic mice
    Alice C Fan
    Stanford University, School of Medicine, Division of Oncology, Department of Medicine, Stanford, CA 94305 5151, USA
    Mol Cancer 7:74. 2008
  3. ncbi Characterization of microRNA expression profiles in normal human tissues
    Yu Liang
    Molecular and Cell Biology R and D, Applied Biosystems, Foster City, CA 94404, USA
    BMC Genomics 8:166. 2007
  4. ncbi Gene expression in stem cells
    Yu Liang
    Molecular Biology Systems Division, Life Technologies, Foster City, CA 94404, USA
    Crit Rev Eukaryot Gene Expr 19:289-300. 2009
  5. ncbi Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme
    Yu Liang
    Preuss Laboratory for Molecular Neuro oncology and Department of Neurological Surgery, University of California San Francisco, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 102:5814-9. 2005
  6. ncbi Microarray analysis of gene expression involved in anther development in rice (Oryza sativa L.)
    Zhen Wang
    Research Center for Molecular and Developmental Biology, Key Laboratory of Photosynthesis and Environmental Molecular Physiology, Institute of Botany, The Chinese Academy of Sciences, 100093, Beijing, China
    Plant Mol Biol 58:721-37. 2005
  7. ncbi A microRNA component of the p53 tumour suppressor network
    Lin He
    Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA
    Nature 447:1130-4. 2007
  8. ncbi Type I collagen is overexpressed in medulloblastoma as a component of tumor microenvironment
    Yu Liang
    Department of Neurological Surgery, Brain Tumor Research Center, University of California San Francisco, San Francisco, CA 94143, USA
    J Neurooncol 86:133-41. 2008
  9. ncbi Identification of noninvasive imaging surrogates for brain tumor gene-expression modules
    Maximilian Diehn
    Department of Radiology, University of California San Diego Medical Center, San Diego, CA 92103, USA
    Proc Natl Acad Sci U S A 105:5213-8. 2008

Collaborators

  • Jason H Moore
  • Caifu Chen
  • Peter S Linsley
  • Alice C Fan
  • Maximilian Diehn
  • Lin He
  • Arti Gaur
  • Dana Ridzon
  • Zhen Wang
  • Jennifer Ho
  • Dean W Felsher
  • Pavan Bachireddy
  • Michael D Kuo
  • David S Wang
  • Soonmee Cha
  • Mahesh Jayaraman
  • MARIANNA M GOLDRICK
  • Kenneth Aldape
  • Christine Nardini
  • Susan McGovern
  • Michele A Cleary
  • Victor R Ambros
  • Xingyue He
  • Aimee L Jackson
  • Wen Xue
  • Zhenyu Xuan
  • Lee P Lim
  • Gregory J Hannon
  • Elisa de Stanchina
  • Jill Magnus
  • David A Jewell
  • Lars Zender
  • Scott W Lowe
  • Mark A Israel
  • Zhihong Xu
  • Chijun Li
  • Yongbiao Xue
  • Yunyuan Xu
  • Dazhong Zhao
  • Kang Chong
  • Lefu Lan

Detail Information

Publications9

  1. ncbi Characterization of microRNA expression levels and their biological correlates in human cancer cell lines
    Arti Gaur
    Norris Cotton Cancer Center, Dartmouth Medical School, Lebanon, New Hampshire 03755, USA
    Cancer Res 67:2456-68. 2007
    ..These findings call attention to the potential of microRNAs to provide etiologic insights as well as to serve as both diagnostic markers and therapeutic targets for many different tumor types...
  2. ncbi A quantitative PCR method to detect blood microRNAs associated with tumorigenesis in transgenic mice
    Alice C Fan
    Stanford University, School of Medicine, Division of Oncology, Department of Medicine, Stanford, CA 94305 5151, USA
    Mol Cancer 7:74. 2008
    ..Our results suggest that specific changes in blood miRNA can be detected during tumorigenesis and tumor regression...
  3. ncbi Characterization of microRNA expression profiles in normal human tissues
    Yu Liang
    Molecular and Cell Biology R and D, Applied Biosystems, Foster City, CA 94404, USA
    BMC Genomics 8:166. 2007
    ..Matched samples from normal state can provide essential baseline references to analyze the variation of miRNA abundance...
  4. ncbi Gene expression in stem cells
    Yu Liang
    Molecular Biology Systems Division, Life Technologies, Foster City, CA 94404, USA
    Crit Rev Eukaryot Gene Expr 19:289-300. 2009
    ..This review summarizes recent advances of gene expression analysis in stem cell research and also discusses critical issues that remain to be elucidated in the search for cancer stem cells markers...
  5. ncbi Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme
    Yu Liang
    Preuss Laboratory for Molecular Neuro oncology and Department of Neurological Surgery, University of California San Francisco, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 102:5814-9. 2005
    ..Our analyses thus identify and validate a prognostic marker of both biologic and clinical significance and provide a series of putative markers for additional evaluation...
  6. ncbi Microarray analysis of gene expression involved in anther development in rice (Oryza sativa L.)
    Zhen Wang
    Research Center for Molecular and Developmental Biology, Key Laboratory of Photosynthesis and Environmental Molecular Physiology, Institute of Botany, The Chinese Academy of Sciences, 100093, Beijing, China
    Plant Mol Biol 58:721-37. 2005
    ..Further characterization of these candidate genes can contribute to the understanding of the molecular mechanism of anther development and the involvement of JA and GA3 signals in the control of anther development in rice...
  7. ncbi A microRNA component of the p53 tumour suppressor network
    Lin He
    Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA
    Nature 447:1130-4. 2007
    ..The p53 network suppresses tumour formation through the coordinated activation of multiple transcriptional targets, and miR-34 may act in concert with other effectors to inhibit inappropriate cell proliferation...
  8. ncbi Type I collagen is overexpressed in medulloblastoma as a component of tumor microenvironment
    Yu Liang
    Department of Neurological Surgery, Brain Tumor Research Center, University of California San Francisco, San Francisco, CA 94143, USA
    J Neurooncol 86:133-41. 2008
    ....
  9. ncbi Identification of noninvasive imaging surrogates for brain tumor gene-expression modules
    Maximilian Diehn
    Department of Radiology, University of California San Diego Medical Center, San Diego, CA 92103, USA
    Proc Natl Acad Sci U S A 105:5213-8. 2008
    ..Our findings provide an in vivo portrait of genome-wide gene expression in GBM and offer a potential strategy for noninvasively selecting patients who may be candidates for individualized therapies...