Alexander K Andrianov

Summary

Country: USA

Publications

  1. doi request reprint Intradermal immunization using coated microneedles containing an immunoadjuvant
    Alexander K Andrianov
    Apogee Technology, Inc, 129 Morgan Drive, Norwood, MA 02062, United States
    Vaccine 30:4355-60. 2012
  2. doi request reprint Microneedles with intrinsic immunoadjuvant properties: microfabrication, protein stability, and modulated release
    Alexander K Andrianov
    Research and Development, Apogee Technology, Inc, 129 Morgan Drive, Norwood, Massachusetts 02062, USA
    Pharm Res 28:58-65. 2011
  3. doi request reprint Effect of environmental factors on hydrolytic degradation of water-soluble polyphosphazene polyelectrolyte in aqueous solutions
    Daniel P DeCollibus
    Apogee Technology, Inc, 129 Morgan Drive, Norwood, Massachusetts 02062, USA
    Biomacromolecules 11:2033-8. 2010
  4. doi request reprint Protein stabilization in aqueous solutions of polyphosphazene polyelectrolyte and non-ionic surfactants
    Alexander Marin
    Apogee Technology, Inc, 129 Morgan Drive, Norwood, Massachusetts 02062, USA
    Biomacromolecules 11:2268-73. 2010
  5. pmc Poly[di(carboxylatophenoxy)phosphazene] is a potent adjuvant for intradermal immunization
    Alexander K Andrianov
    Apogee Technology, Inc, 129 Morgan Drive, Norwood, MA 02062, USA
    Proc Natl Acad Sci U S A 106:18936-41. 2009

Collaborators

Detail Information

Publications5

  1. doi request reprint Intradermal immunization using coated microneedles containing an immunoadjuvant
    Alexander K Andrianov
    Apogee Technology, Inc, 129 Morgan Drive, Norwood, MA 02062, United States
    Vaccine 30:4355-60. 2012
    ..PCPP, a synthetic polyphosphazene macromolecular compound, is discussed as an example of such material that can potentially enable the technology as a microfabrication agent and a potent intradermal immunoadjuvant...
  2. doi request reprint Microneedles with intrinsic immunoadjuvant properties: microfabrication, protein stability, and modulated release
    Alexander K Andrianov
    Research and Development, Apogee Technology, Inc, 129 Morgan Drive, Norwood, Massachusetts 02062, USA
    Pharm Res 28:58-65. 2011
    ..To address this challenge, we investigated microneedles coated with polyphosphazene polyelectrolyte, which served both as microfabrication material and an immunoadjuvant compound...
  3. doi request reprint Effect of environmental factors on hydrolytic degradation of water-soluble polyphosphazene polyelectrolyte in aqueous solutions
    Daniel P DeCollibus
    Apogee Technology, Inc, 129 Morgan Drive, Norwood, Massachusetts 02062, USA
    Biomacromolecules 11:2033-8. 2010
    ..The results can be potentially explained on the basis of acid promoted hydrolysis mechanism and macromolecular interactions in the system...
  4. doi request reprint Protein stabilization in aqueous solutions of polyphosphazene polyelectrolyte and non-ionic surfactants
    Alexander Marin
    Apogee Technology, Inc, 129 Morgan Drive, Norwood, Massachusetts 02062, USA
    Biomacromolecules 11:2268-73. 2010
    ..The phenomenon is studied in the context of macromolecular interactions in the system and is linked to the formation of PCPP-protein and PCPP-protein-surfactant complexes...
  5. pmc Poly[di(carboxylatophenoxy)phosphazene] is a potent adjuvant for intradermal immunization
    Alexander K Andrianov
    Apogee Technology, Inc, 129 Morgan Drive, Norwood, MA 02062, USA
    Proc Natl Acad Sci U S A 106:18936-41. 2009
    ..It also accelerates the microneedle fabrication process and reduces its dependence on the use of surfactants. In this way, PCPP-coated microneedles may enable effective intradermal vaccination from an adjuvanted patch delivery system...