William B Grant

Summary

Affiliation: and Health Research Center
Country: USA

Publications

  1. pmc Effect of follow-up time on the relation between prediagnostic serum 25-hydroxyvitamin D and all-cause mortality rate
    William B Grant
    Sunlight, Nutrition, and Health Research Center San Francisco, CA USA
    Dermatoendocrinol 4:198-202. 2012
  2. pmc Role of solar UVB irradiance and smoking in cancer as inferred from cancer incidence rates by occupation in Nordic countries
    William B Grant
    Sunlight, Nutrition, and Health Research Center San Francisco, CA USA
    Dermatoendocrinol 4:203-11. 2012
  3. pmc An ecological study of cancer mortality rates in California, 1950-64, with respect to solar UVB and smoking indices
    William B Grant
    Sunlight, Nutrition, and Health Research Center SUNARC San Francisco, CA USA
    Dermatoendocrinol 4:176-82. 2012
  4. pmc On the roles of solar UV irradiance and smoking on the diagnosis of second cancers after diagnosis of melanoma
    William B Grant
    Sunlight, Nutrition and Health Research Center San Francisco, CA USA
    Dermatoendocrinol 4:12-7. 2012
  5. doi request reprint A multicountry ecological study of cancer incidence rates in 2008 with respect to various risk-modifying factors
    William B Grant
    Sunlight, Nutrition, and Health Research Center, P O Box 641603, San Francisco, CA 94164 1603, USA
    Nutrients 6:163-89. 2014
  6. pmc Molecular link between vitamin D and cancer prevention
    Meis Moukayed
    School of Arts and Sciences, American University in Dubai, P O Box 28282, Dubai, UAE
    Nutrients 5:3993-4021. 2013
  7. doi request reprint Benefits of ultraviolet-B irradiance and vitamin D in youth
    William B Grant
    Sunlight, Nutrition, and Health Research Center, P O Box 641603, San Francisco, CA 94164 1603, USA
    J Steroid Biochem Mol Biol 136:221-3. 2013
  8. ncbi request reprint Update on evidence that support a role of solar ultraviolet-B irradiance in reducing cancer risk
    William B Grant
    Sunlight, Nutrition, and Health Research Center, P O Box 641603, San Francisco, CA 94164 1603, USA
    Anticancer Agents Med Chem 13:140-6. 2013
  9. doi request reprint Vitamin D: evidence and controversies: comment on the article by Gilaberte et al
    William B Grant
    Sunlight, Nutrition, and Health Research Center, San Francisco, USA
    Actas Dermosifiliogr 103:591-4. 2012
  10. ncbi request reprint Ultraviolet exposure and non-Hodgkin's lymphoma: beneficial and adverse effects?
    William B Grant
    Sunlight, Nutrition, and Health Research Center, P O Box 641603, San Francisco, CA, 94164 1603, USA
    Cancer Causes Control 23:653-5. 2012

Detail Information

Publications93

  1. pmc Effect of follow-up time on the relation between prediagnostic serum 25-hydroxyvitamin D and all-cause mortality rate
    William B Grant
    Sunlight, Nutrition, and Health Research Center San Francisco, CA USA
    Dermatoendocrinol 4:198-202. 2012
    ..This paper recommends that meta-analyses of prospective cohort studies account for follow-up time and, if possible, that studies measure serum 25(OH)D concentration every 2-4 y...
  2. pmc Role of solar UVB irradiance and smoking in cancer as inferred from cancer incidence rates by occupation in Nordic countries
    William B Grant
    Sunlight, Nutrition, and Health Research Center San Francisco, CA USA
    Dermatoendocrinol 4:203-11. 2012
    ..These results generally agree with findings from other studies. These results provide more support for the UVB-vitamin D-cancer hypothesis and suggest that widespread fear of chronic solar ultraviolet (UV) irradiance may be misplaced...
  3. pmc An ecological study of cancer mortality rates in California, 1950-64, with respect to solar UVB and smoking indices
    William B Grant
    Sunlight, Nutrition, and Health Research Center SUNARC San Francisco, CA USA
    Dermatoendocrinol 4:176-82. 2012
    ..After that period, no further such correlations were found. The reasons may hypothetically include reduced NMSC mortality rates, high immigration rates, movement from rural to urban locations and reduced solar UVB irradiance...
  4. pmc On the roles of solar UV irradiance and smoking on the diagnosis of second cancers after diagnosis of melanoma
    William B Grant
    Sunlight, Nutrition and Health Research Center San Francisco, CA USA
    Dermatoendocrinol 4:12-7. 2012
    ..Thus, guidelines on UV irradiance should emphasize regular moderate UVB irradiance rather than avoidance for those who can tan...
  5. doi request reprint A multicountry ecological study of cancer incidence rates in 2008 with respect to various risk-modifying factors
    William B Grant
    Sunlight, Nutrition, and Health Research Center, P O Box 641603, San Francisco, CA 94164 1603, USA
    Nutrients 6:163-89. 2014
    ..Single-country ecological studies have inversely correlated nearly all of these cancers with solar ultraviolet-B doses. These results can provide guidance for prevention of cancer. ..
  6. pmc Molecular link between vitamin D and cancer prevention
    Meis Moukayed
    School of Arts and Sciences, American University in Dubai, P O Box 28282, Dubai, UAE
    Nutrients 5:3993-4021. 2013
    ....
  7. doi request reprint Benefits of ultraviolet-B irradiance and vitamin D in youth
    William B Grant
    Sunlight, Nutrition, and Health Research Center, P O Box 641603, San Francisco, CA 94164 1603, USA
    J Steroid Biochem Mol Biol 136:221-3. 2013
    ..Some of the effects of higher solar UVB irradiance and serum 25(OH)D concentrations are evident in youth, although some may become apparent later in life. This article is part of a Special Issue entitled 'Vitamin D Workshop'...
  8. ncbi request reprint Update on evidence that support a role of solar ultraviolet-B irradiance in reducing cancer risk
    William B Grant
    Sunlight, Nutrition, and Health Research Center, P O Box 641603, San Francisco, CA 94164 1603, USA
    Anticancer Agents Med Chem 13:140-6. 2013
    ..Because only vitamin D production has been proposed to explain the UVB-cancer link, studies reviewed in this paper should be considered strong evidence for the hypothesis...
  9. doi request reprint Vitamin D: evidence and controversies: comment on the article by Gilaberte et al
    William B Grant
    Sunlight, Nutrition, and Health Research Center, San Francisco, USA
    Actas Dermosifiliogr 103:591-4. 2012
    ..Risk of nonmelanoma skin cancer is higher, but such cancers are seldom fatal, and a study in Denmark found a 9% reduction in 10-year all-cause mortality rate for patients diagnosed with basal cell carcinoma...
  10. ncbi request reprint Ultraviolet exposure and non-Hodgkin's lymphoma: beneficial and adverse effects?
    William B Grant
    Sunlight, Nutrition, and Health Research Center, P O Box 641603, San Francisco, CA, 94164 1603, USA
    Cancer Causes Control 23:653-5. 2012
    ..It is suggested that reduced risk arises from vitamin D production from UVB irradiance, while increased risk arises from immunosuppression associated with UVA irradiance. The ratio of UVA to UVB increases with increasing latitude...
  11. doi request reprint Review Article: Health benefit of increased serum 25(OH)D levels from oral intake and ultraviolet-B irradiance in the Nordic countries
    William B Grant
    Sunlight, Nutrition, and Health Research Center, San Francisco, CA, USA
    Scand J Public Health 39:70-8. 2011
    ..This report estimates the reduction in mortality rates for the five Nordic countries for an increase in population mean serum 25-hydroxyvitamin D level to 105 nmol/L...
  12. doi request reprint Requirements for Vitamin D across the life span
    William B Grant
    Sunlight, Nutrition, and Health Research Center SUNARC, San Francisco, CA, USA
    Biol Res Nurs 13:120-33. 2011
    ....
  13. doi request reprint An estimate of the economic burden and premature deaths due to vitamin D deficiency in Canada
    William B Grant
    Sunlight, Nutrition, and Health Research Center SUNARC, San Francisco, CA 94164 1603, USA
    Mol Nutr Food Res 54:1172-81. 2010
    ..9% (3.8-10.0%) or $14.4 billion ($8.0 billion-$20.1 billion) less the cost of the program. It is recommended that Canadian health policy leaders consider measures to increase serum 25(OH)D levels for all Canadians...
  14. ncbi request reprint Current impediments to acceptance of the ultraviolet-B-vitamin D-cancer hypothesis
    William B Grant
    Sunlight, Nutrition, and Health Research Center SUNARC, San Francisco, CA 94164 1603, USA
    Anticancer Res 29:3597-604. 2009
    ..While additional randomized controlled trials would, of course, be helpful, the current evidence seems to satisfy the criteria for causality as outlined by A. Bradford Hill...
  15. doi request reprint Ecological studies of ultraviolet B, vitamin D and cancer since 2000
    William B Grant
    Sunlight, Nutrition, and Health Research Center, San Francisco, CA, USA
    Ann Epidemiol 19:446-54. 2009
    ..The purpose of this review is to summarize ecological studies of solar ultraviolet B (UVB), vitamin D and cancer since 2000...
  16. ncbi request reprint A multicountry ecological study of risk-modifying factors for prostate cancer: apolipoprotein E epsilon4 as a risk factor and cereals as a risk reduction factor
    William B Grant
    Sunlight, Nutrition, and Health Research Center, P O Box 641603, San Francisco, CA 94164 1603, USA
    Anticancer Res 30:189-99. 2010
    ..The ApoE4-diet-GDP hypothesis may explain the higher risk of prostate cancer for African Americans and should form the basis for further studies...
  17. doi request reprint Does vitamin D reduce the risk of dementia?
    William B Grant
    Sunlight, Nutrition, and Health Research Center SUNARC, P O Box 641603, San Francisco, CA 94164 1603, USA
    J Alzheimers Dis 17:151-9. 2009
    ..Although this evidence is supportive, there do not appear to be observational studies of incidence of dementia with respect to prediagnostic serum 25(OH)D or vitamin D supplementation. Such studies now appear to be warranted...
  18. doi request reprint Estimated benefit of increased vitamin D status in reducing the economic burden of disease in western Europe
    William B Grant
    Sunlight, Nutrition, and Health Research Center SUNARC, San Francisco, CA 94164 1603, USA
    Prog Biophys Mol Biol 99:104-13. 2009
    ..Additional randomized controlled trials are warranted to evaluate the benefits and risks of vitamin D supplementation. However, steps to increase serum 25(OH)D levels can be implemented now based on what is already known...
  19. ncbi request reprint Air pollution in relation to U.S. cancer mortality rates: an ecological study; likely role of carbonaceous aerosols and polycyclic aromatic hydrocarbons
    William B Grant
    Sunlight, Nutrition and Health Research Center SUNARC, P O Box 641603, San Francisco, CA 94164 1603, USA
    Anticancer Res 29:3537-45. 2009
    ..Air pollution also plays a role in cancer risk...
  20. doi request reprint Relation between prediagnostic serum 25-hydroxyvitamin D level and incidence of breast, colorectal, and other cancers
    William B Grant
    Sunlight, Nutrition, and Health Research Center SUNARC, P O Box 641603, San Francisco, CA 94164 1603, USA
    J Photochem Photobiol B 101:130-6. 2010
    ..Future prospective studies should include more serum 25(OH)D level measurements during the study course...
  21. doi request reprint Health benefits of higher serum 25-hydroxyvitamin D levels in The Netherlands
    William B Grant
    Sunlight, Nutrition, and Health Research Center SUNARC, P O Box 641603, San Francisco, CA 94164 1603, USA
    J Steroid Biochem Mol Biol 121:456-8. 2010
    ..Doing so would pose only minimal increased risks of melanoma or skin cancer or hypercalcemia...
  22. doi request reprint Possible role of serum 25-hydroxyvitamin D in black-white health disparities in the United States
    William B Grant
    Sunlight, Nutrition, and Health Research Center SUNARC, San Francisco, CA 94164 1603, USA
    J Am Med Dir Assoc 11:617-28. 2010
    ....
  23. ncbi request reprint Skin aging from ultraviolet irradiance and smoking reduces risk of melanoma: epidemiological evidence
    William B Grant
    CSunlight, Nutrition, and Health Research Center SUNARC, P O Box 641603, San Francisco, CA 94164 1603, USA
    Anticancer Res 28:4003-8. 2008
    ..Development of elastosis seems to explain why long-term smoking and chronic UV irradiance reduce the risk of melanoma. Further work is required to elucidate the mechanism whereby elastosis retards and reduces the development of melanoma...
  24. doi request reprint An estimate of the global reduction in mortality rates through doubling vitamin D levels
    W B Grant
    Sunlight, Nutrition, and Health Research Center, San Francisco, CA 94164 1603, USA
    Eur J Clin Nutr 65:1016-26. 2011
    ..The goal of this work is to estimate the reduction in mortality rates for six geopolitical regions of the world under the assumption that serum 25-hydroxyvitamin D (25(OH)D) levels increase from 54 to 110 nmol/l...
  25. ncbi request reprint A multicountry ecologic study of risk and risk reduction factors for prostate cancer mortality
    William B Grant
    12 Sir Francis Wyatt Place, Newport News, VA 23606 3660, USA
    Eur Urol 45:271-9. 2004
    ..The objective of this research is to identify and determine the relative importance of dietary and environmental risk and risk reduction factors for prostate cancer mortality...
  26. ncbi request reprint A critical review of studies on vitamin D in relation to colorectal cancer
    William B Grant
    SUNARC, San Francisco, CA 94109, USA
    Nutr Cancer 48:115-23. 2004
    ..Further study is required to elucidate the mechanisms and develop guidelines for optimal vitamin D sources and serum levels of vitamin D metabolites...
  27. ncbi request reprint Does solar ultraviolet irradiation affect cancer mortality rates in China?
    William B Grant
    SUNARC, San Francisco, CA 94109 2510, USA
    Asian Pac J Cancer Prev 8:236-42. 2007
    ..Liver cancer and NPC are linked to viruses, and UVR may increase the risk through immunosuppression. Further studies are warranted...
  28. ncbi request reprint The effect of solar UVB doses and vitamin D production, skin cancer action spectra, and smoking in explaining links between skin cancers and solid tumours
    William B Grant
    Sunlight, Nutrition, and Health Research Center SUNARC, San Francisco, CA 94109, USA
    Eur J Cancer 44:12-5. 2008
    ..In Nordic countries, less skin is generally exposed (in head and neck regions, the most frequent sites of squamous cell carcinoma) resulting in reduced vitamin D production...
  29. ncbi request reprint Ecologic studies of solar UV-B radiation and cancer mortality rates
    William B Grant
    Recent Results Cancer Res 164:371-7. 2003
    ..These studies add further support for the role of UV-B radiation and vitamin D in reducing the risk of a large number of cancers...
  30. ncbi request reprint An ecological study of cancer mortality rates including indices for dietary iron and zinc
    William B Grant
    Sunlight, Nutrition and Health Research Center, San Francisco, CA 94109 1603, USA
    Anticancer Res 28:1955-63. 2008
    ..Dietary iron and zinc affect the risk of cancer, with dietary iron generally correlated with increased risk and dietary zinc with reduced risk. However, zinc supplements have been found correlated with increased risk of cancer...
  31. ncbi request reprint Health benefits of solar UV-B radiation through the production of vitamin D. Comment and response
    William B Grant
    Photochem Photobiol Sci 2:1307-8; discussion 1308-10. 2003
  32. ncbi request reprint Comment on "the effects on human health from stratospheric ozone depletion and its interactions with climate change" by M. Norval, A. P. Cullen, F. R. de Gruijl, J. Longstreth, Y. Takizawa, R. M. Lucas, F. P. Noonan and J. C. van der Leun, Photochem. Phot
    William B Grant
    Sunlight, Nutrition, and Health Research Center SUNARC, 2115 Van Ness Avenue, San Francisco, CA 94109 2510, USA
    Photochem Photobiol Sci 6:912-5; discussion 916-8. 2007
    ..If this result is correct, melanoma risk is not related to ozone depletion. We consider the net effect of solar UVB on human health to be beneficial at or near current levels...
  33. ncbi request reprint An ecologic study of cancer mortality rates in Spain with respect to indices of solar UVB irradiance and smoking
    William B Grant
    Sunlight, Nutrition, and Health Research Center SUNARC 2115 Van Ness Ave, MB 101 San Francisco, CA 94109 2510, USA
    Int J Cancer 120:1123-8. 2007
    ..They also provide more evidence that melanoma and NMSC have different etiologies...
  34. ncbi request reprint Fit to play: the fitness effect on physically challenging flute repertoire
    William B Grant
    Sunlight, Nutrition, and Health Research Center, San Francisco, CA 94164 1603, USA
    Med Probl Perform Art 26:117. 2011
    ..Overlooked in any of the papers hypothesizing about his death was a discussion of the likely role of very low serum 25-hydroxyvitamin D [25(OH)D] level in contributing to his untimely death...
  35. doi request reprint Solar ultraviolet irradiance and cancer incidence and mortality
    William B Grant
    Sunlight, Nutrition and Health Research Center SUNARC, San Francisco, CA, USA
    Adv Exp Med Biol 624:16-30. 2008
    ..These findings are probably still approximately correct, if not on the low side, with respect to vitamin D because of the additional benefits found recently, such as protection against infectious diseases...
  36. ncbi request reprint Ecological studies of the UVB-vitamin D-cancer hypothesis
    William B Grant
    Sunlight, Nutrition, and Health Research Center, P O Box 641603, San Francisco, CA 94164 1603, USA
    Anticancer Res 32:223-36. 2012
    ..This paper reviews ecological studies of the ultraviolet-B (UVB)-vitamin D-cancer hypothesis based on geographical variation of cancer incidence and/or mortality rates...
  37. doi request reprint Ultraviolet B irradiance and vitamin D status are inversely associated with incidence rates of pancreatic cancer worldwide
    Sharif B Mohr
    Naval Health Research Center, San Diego, CA, USA
    Pancreas 39:669-74. 2010
    ..To determine if an inverse association exits between latitude, ultraviolet B (UVB) irradiance and incidence rates of pancreatic cancer worldwide...
  38. ncbi request reprint Comparisons of estimated economic burdens due to insufficient solar ultraviolet irradiance and vitamin D and excess solar UV irradiance for the United States
    William B Grant
    Sunlight, Nutrition and Health Research Center SUNARC, 2107 Van Ness Avenue, Suite 403B, San Francisco, CA 94109 2529, USA
    Photochem Photobiol 81:1276-86. 2005
    ..Further research is required to confirm these estimates...
  39. ncbi request reprint An ecologic study of dietary and solar ultraviolet-B links to breast carcinoma mortality rates
    William B Grant
    Newport News, Virginia, USA
    Cancer 94:272-81. 2002
    ..Case-control and cohort studies generally find a variety of chemical, nonfat dietary, environmental, genetic, lifestyle, and reproductive factors to be important...
  40. ncbi request reprint The association of solar ultraviolet B (UVB) with reducing risk of cancer: multifactorial ecologic analysis of geographic variation in age-adjusted cancer mortality rates
    William B Grant
    Sunlight, Nutrition and Health Research Center SUNARC, 2107 Van Ness Avenue, Suite 403B, San Francisco, CA 94109 2529, USA
    Anticancer Res 26:2687-99. 2006
    ..However, the previous ecologic study of UVB and cancer mortality rates in the U.S. (Grant, 2002) did not include other risk factors in the analysis...
  41. ncbi request reprint The likely role of vitamin D from solar ultraviolet-B irradiance in increasing cancer survival
    William B Grant
    Sunlight, Nutrition and Health Research Center SUNARC, San Francisco, CA 94109 2529, USA
    Anticancer Res 26:2605-14. 2006
    ..Solar ultraviolet-B (UVB) and vitamin D have been found inversely correlated with cancer incidence, mortality, and survival rates in many studies...
  42. ncbi request reprint Epidemiology of disease risks in relation to vitamin D insufficiency
    William B Grant
    Sunlight, Nutrition and Health Research Center SUNARC, 2107 Van Ness Avenue, Suite 403B, San Francisco, CA 94109 2529, USA
    Prog Biophys Mol Biol 92:65-79. 2006
    ..It is noted that mechanisms whereby vitamin D exerts its effect are generally well understood for the various conditions and diseases discussed here...
  43. pmc Lower vitamin-D production from solar ultraviolet-B irradiance may explain some differences in cancer survival rates
    William B Grant
    Sunlight, Nutrition and Health Research Center, San Francisco, CA 94109 2529, USA
    J Natl Med Assoc 98:357-64. 2006
    ..Based on these results, it seems worthwhile to conduct observational, prevention and intervention studies to further test the hypothesis that vitamin D can reduce the risk of cancer incidence and death...
  44. ncbi request reprint An estimate of cancer mortality rate reductions in Europe and the US with 1,000 IU of oral vitamin D per day
    William B Grant
    Sunlight, Nutrition and Health Research Center, San Francisco, CA 94109 2510, USA
    Recent Results Cancer Res 174:225-34. 2007
    ..Providing 1,000 IU of vitamin D per day for all adult Americans would cost about $1 billion; the expected benefits for cancer would be in the range of $16-25 billion in addition to other health benefits of vitamin D...
  45. doi request reprint Hypothesis--ultraviolet-B irradiance and vitamin D reduce the risk of viral infections and thus their sequelae, including autoimmune diseases and some cancers
    William B Grant
    Sunlight, Nutrition, and Health Research Center, San Francisco, CA, USA
    Photochem Photobiol 84:356-65. 2008
    ..In general, the evidence supports the hypothesis. However, further work is required to evaluate this hypothesis...
  46. ncbi request reprint Are low ultraviolet B and high animal protein intake associated with risk of renal cancer?
    Sharif B Mohr
    Department of Family and Preventive Medicine, University of California, San Diego, CA, USA
    Int J Cancer 119:2705-9. 2006
    ..0001) were positively associated (R(2) = 0.68, p < 0.0001). Lower levels of UVB irradiance and higher intakes of calories from animal sources were independently associated with higher incidence rates of kidney cancer...
  47. ncbi request reprint Benefits and requirements of vitamin D for optimal health: a review
    William B Grant
    Sunlight Nutrition and Health Research Center SUNARC, 2107 Van Ness Ave, Ste 403B, San Francisco, CA 94109, USA
    Altern Med Rev 10:94-111. 2005
    ..In the absence of adequate solar UVB irradiation due to season, latitude, or lifestyle, vitamin D can be obtained from fortified food, oily fish, vitamin D supplements, and artificial sources of UVB radiation...
  48. ncbi request reprint Commentary: time for public health action on vitamin D for cancer risk reduction
    William B Grant
    Sunlight, Nutrition and Health Research Center, SUNARC, 2107 Van Ness Avenue, Suite 403B, San Francisco, CA 94109 2529, USA
    Int J Epidemiol 35:224-5. 2006
  49. doi request reprint Vitamin D deficiency and mortality risk in the general population: a meta-analysis of prospective cohort studies
    Armin Zittermann
    Clinic for Thoracic and Cardiovascular Surgery, Heart Centre North Rhine Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany
    Am J Clin Nutr 95:91-100. 2012
    ..Low vitamin D status may increase mortality risk...
  50. pmc Are Hill's criteria for causality satisfied for vitamin D and periodontal disease?
    William B Grant
    Sunlight, Nutrition and Health Research Center SUNARC San Francisco, CA USA
    Dermatoendocrinol 2:30-6. 2010
    ..If confirmed, dentists and periodontists could perform a valuable service to their patients by discussing the importance of adequate vitamin D status and how to avoid deficiency...
  51. pmc Dr. Frank caldwell garland, june 20, 1950-august 17, 2010
    William B Grant
    Sunlight, Nutrition and Health Research Center SUNARC San Francisco, CA USA
    Dermatoendocrinol 2:46-9. 2010
    ..The impact on vitamin D research by both Frank Garland and Cedric Garland has been immense. Health policy leaders will realize this in the near future, providing a rich legacy for humanity...
  52. doi request reprint Secondary hyperparathyroidism: benign bystander or culpable contributor to adverse health outcomes?
    Alan N Peiris
    Tennessee State University, Johnson City, TN, USA
    South Med J 105:36-42. 2012
    ..Despite these caveats, PTH values provide useful clinical diagnostic and prognostic information in monitoring many chronic ailments such as heart and renal failure and multiple sclerosis...
  53. ncbi request reprint Geographic variation of prostate cancer mortality rates in the United States: Implications for prostate cancer risk related to vitamin D
    William B Grant
    Int J Cancer 111:470-1; author reply 472. 2004
  54. ncbi request reprint Role of ultraviolet B irradiance and vitamin D in prevention of ovarian cancer
    Cedric F Garland
    Department of Family and Preventive Medicine, University of California San Diego, La Jolla, California 92093 0631, USA
    Am J Prev Med 31:512-4. 2006
    ..This suggests that lower levels of solar irradiance might be associated with higher risk of ovarian cancer. Laboratory findings also suggest that low levels of vitamin D metabolites could play a role in the etiology of ovarian cancer...
  55. ncbi request reprint Vitamin D and Cancer Risk among American Indians
    William B Grant
    Cancer Epidemiol Biomarkers Prev 16:183. 2007
  56. doi request reprint Ecologic approach is a powerful tool for cancer research
    William B Grant
    Eur J Cancer Prev 17:384. 2008
  57. ncbi request reprint Re: Cancer as a risk factor for long-term cognitive deficits and dementia
    William B Grant
    J Natl Cancer Inst 97:1549; author reply 1550. 2005
  58. doi request reprint Relationship between low ultraviolet B irradiance and higher breast cancer risk in 107 countries
    Sharif B Mohr
    Department of Family and Preventive Medicine, University of California San Diego, La Jolla, California 92093 0631, USA
    Breast J 14:255-60. 2008
    ..81 (p < 0.0001). There was a protective effect of UVB irradiance on risk of breast cancer that was independent of fertility rate, proportion of the population overweight, alcohol intake, animal energy intake, and other covariates...
  59. doi request reprint Solar ultraviolet B radiation compared with prostate cancer incidence and mortality rates in United States
    Janet L Colli
    Department of Urology, University of Alabama, Birmingham, School of Medicine, Birmingham, Alabama 35294, USA
    Urology 71:531-5. 2008
    ..Another objective was to explore whether the annual prostate cancer rates correlated more strongly with the cumulative UVB exposure for the year or for exposure during certain seasons...
  60. ncbi request reprint A meta-analysis of second cancers after a diagnosis of nonmelanoma skin cancer: additional evidence that solar ultraviolet-B irradiance reduces the risk of internal cancers
    William B Grant
    J Steroid Biochem Mol Biol 103:668-74. 2007
    ..This assumption has been questioned...
  61. ncbi request reprint Vitamin D and prevention of colorectal cancer
    Edward D Gorham
    Naval Health Research Center, San Diego, CA 92186, USA
    J Steroid Biochem Mol Biol 97:179-94. 2005
    ..Inadequate photosynthesis or oral intake of Vitamin D are associated with high incidence rates of colorectal cancer, but the dose-response relationship has not been adequately studied...
  62. ncbi request reprint Is ultraviolet B irradiance inversely associated with incidence rates of endometrial cancer: an ecological study of 107 countries
    Sharif B Mohr
    Department of Family and Preventive Medicine 0631C, University of California San Diego, La Jolla CA, USA
    Prev Med 45:327-31. 2007
    ....
  63. doi request reprint Re: Prospective study of vitamin D and cancer mortality in the United States
    William B Grant
    J Natl Cancer Inst 100:826. 2008
  64. ncbi request reprint An estimate of premature cancer mortality in the U.S. due to inadequate doses of solar ultraviolet-B radiation
    William B Grant
    Cancer 94:1867-75. 2002
    ..The purpose of the current study was to determine how many types of cancer are affected by solar radiation and how many premature deaths from cancer occur due to insufficient ultraviolet (UV)-B radiation...
  65. doi request reprint Sun beds and cod liver oil as vitamin D sources
    Alina Carmen Porojnicu
    Department of Radiation Biology, Rikshospitalet Radiumhospitalet Medical Center, Montebello, 0310 Oslo, Norway
    J Photochem Photobiol B 91:125-31. 2008
    ..Within eight weeks after the last exposure the 25(OH)D(3) level decreased to the initial value in all volunteers irrespective of vitamin D supplementation or not...
  66. ncbi request reprint What is the dose-response relationship between vitamin D and cancer risk?
    Cedric F Garland
    Department of Family and Preventive Medicine, School of Medicine, University of California San Diego, 9500 Gilman Dr, La Jolla, CA 92093, USA
    Nutr Rev 65:S91-5. 2007
  67. ncbi request reprint Vitamin D as a risk reduction factor for colorectal cancer
    William B Grant
    Am Fam Physician 67:465. 2003
  68. ncbi request reprint Optimal vitamin D status for colorectal cancer prevention: a quantitative meta analysis
    Edward D Gorham
    University of California San Diego, Department of Family and Preventive Medicine, School of Medicine, La Jolla, California, USA
    Am J Prev Med 32:210-6. 2007
    ..Previous studies, such as the Women's Health Initiative, have shown that a low dose of vitamin D did not protect against colorectal cancer, yet a meta-analysis indicates that a higher dose may reduce its incidence...
  69. ncbi request reprint Evidence supporting the role of vitamin D in reducing the risk of cancer
    William B Grant
    J Intern Med 252:178-9; author reply 179-80. 2002
  70. pmc Vitamin D may reduce prostate cancer metastasis by several mechanisms including blocking Stat3
    William B Grant
    Am J Pathol 173:1589-90. 2008
  71. ncbi request reprint Smoking, alcohol, diet and low vitamin D overlooked as modern cancer risk factors
    William B Grant
    Int J Cancer 119:722; author reply 723. 2006
  72. ncbi request reprint Obesity and Alzheimer disease: roles of diet and genetics
    William B Grant
    Arch Intern Med 164:109-10; author reply 110. 2004
  73. pmc High vitamin D and calcium requirements during pregnancy and tooth loss
    William B Grant
    Am J Public Health 98:1931-2. 2008
  74. ncbi request reprint Solar UV-B radiation is linked to the geographic variation of mortality from systemic lupus erythematosus in the USA
    William B Grant
    Lupus 13:281-2. 2004
  75. doi request reprint The health benefits of vitamin D greatly outweigh the health risks
    William B Grant
    Bioessays 30:506-7; author reply 510-1. 2008
  76. ncbi request reprint Re: Fruit and vegetable intake and risk of major chronic disease
    William B Grant
    J Natl Cancer Inst 97:608; author reply 608-9. 2005
  77. ncbi request reprint Smoking overlooked as an important risk factor for squamous cell carcinoma
    William B Grant
    Arch Dermatol 140:362-3; author reply 363. 2004
  78. ncbi request reprint Diet and risk of dementia: does fat matter? The Rotterdam Study
    William B Grant
    Neurology 60:2020-1. 2003
  79. ncbi request reprint Cholecalciferol, not ergocalciferol, should be used for vitamin D supplementation
    William B Grant
    Age Ageing 35:645; author reply 645. 2006
  80. doi request reprint Vitamin D and the seasonality of type 2 diabetes
    Peter Doro
    Med Hypotheses 71:317-8. 2008
  81. ncbi request reprint Differences in vitamin-D status may explain black-white differences in breast cancer survival rates
    William B Grant
    J Natl Med Assoc 100:1040. 2008
  82. doi request reprint Vitamin D, periodontal disease, tooth loss, and cancer risk
    William B Grant
    Lancet Oncol 9:612-3. 2008
  83. ncbi request reprint Vitamin D and prevention of breast cancer: pooled analysis
    Cedric F Garland
    Department of Family and Preventive Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    J Steroid Biochem Mol Biol 103:708-11. 2007
    ....
  84. doi request reprint Variations in vitamin D production could possibly explain the seasonality of childhood respiratory infections in Hawaii
    William B Grant
    Pediatr Infect Dis J 27:853. 2008
  85. ncbi request reprint Smoking, Parkinson's disease, and melanoma
    William B Grant
    Cancer Epidemiol Biomarkers Prev 16:2517-8; author reply 2518. 2007
  86. ncbi request reprint Comments on E. Giovannucci, "Insulin, insulin-like growth factors and colon cancer: a review of the evidence"
    William B Grant
    J Nutr 132:2324; author reply 2325. 2002
  87. ncbi request reprint Air pollution and breast cancer
    William B Grant
    Epidemiology 16:421. 2005