- No evidence of drug-induced pancreatitis in rats treated with exenatide for 13 weeksK Tatarkiewicz
Amylin Pharmaceuticals, LLC, San Diego, CA 92121, USA
Diabetes Obes Metab 15:417-26. 2013..This study evaluated the long-term effects of the GLP-1RA exenatide on pancreatic exocrine structure and function in the Zucker diabetic fatty (ZDF) rat model of type 2 diabetes...
- Exenatide does not evoke pancreatitis and attenuates chemically induced pancreatitis in normal and diabetic rodentsKrystyna Tatarkiewicz
Amylin Pharmaceuticals, San Diego, CA, USA
Am J Physiol Endocrinol Metab 299:E1076-86. 2010..In conclusion, exenatide did not modify plasma amylase and lipase concentrations in rodents without pancreatitis and improved chemically induced pancreatitis in normal and diabetic rodents...