C L Manthey
Affiliation: Amgen Inc
- SB202190, a selective inhibitor of p38 mitogen-activated protein kinase, is a powerful regulator of LPS-induced mRNAs in monocytesC L Manthey
Department of Biology, Amgen, Inc, Boulder, Colorado 80301, USA
J Leukoc Biol 64:409-17. 1998..The results provide pharmacological evidence that p38 may be a key mediator of inducible gene expression in monocytes, but its role is stimulus and gene specific...
- Differential expression and activation of p38 mitogen-activated protein kinase alpha, beta, gamma, and delta in inflammatory cell lineagesK K Hale
Department of Biology, Amgen, Boulder, CO 80301, USA
J Immunol 162:4246-52. 1999..Additional studies will be needed to define the contribution of p38delta to macrophage, neutrophil, and T cell functions, and of p38beta to signaling in endothelial cells and T cells...
- Molecular cloning and characterization of a novel p38 mitogen-activated protein kinaseX S Wang
Amgen Inc, Boulder, Colorado 80301, USA
J Biol Chem 272:23668-74. 1997..Taken together, these data indicate that p38delta is a new member of the p38 MAPK family and that p38delta likely has functions distinct from that of p38alpha...