C L Farrell
Affiliation: Amgen Inc
- The effects of keratinocyte growth factor in preclinical models of mucositisC L Farrell
Department of Pathology, Amgen, Inc, One Amgen Center Drive, Thousand Oaks CA 91320, USA
Cell Prolif 35:78-85. 2002..These data suggest that KGF may be useful for the prevention or treatment of mucositis in patients treated with regimens of cancer therapy that have gastrointestinal toxicity...
- Effects of keratinocyte growth factor in the squamous epithelium of the upper aerodigestive tract of normal and irradiated miceC L Farrell
Department of Pathology, Amgen Inc, Thousand Oaks, CA 91320 1789, USA
Int J Radiat Biol 75:609-20. 1999..To investigate the effects of keratinocyte growth factor (KGF) on the structure of the stratified squamous epithelium of the tongue, buccal mucosa and oesophagus of normal and irradiated mice...
- Keratinocyte growth factor protects mice from chemotherapy and radiation-induced gastrointestinal injury and mortalityC L Farrell
Amgen Center, Thousand Oaks, California 91320 1789, USA
Cancer Res 58:933-9. 1998..These data indicate that KGF may be therapeutically useful to lessen the intestinal side effects of current cancer therapy regimens...
- The effect of keratinocyte growth factor on healing of manifest radiation ulcers in mouse tongue epitheliumW Dorr
Klinik and Poliklinik für Strahlentherapie and Radioonkologie, Medizinische fakultät Carl Gustav Carus der Technishen Universität, D 01307 Dresden, Germany
Cell Prolif 35:86-92. 2002..These data suggest that during tumour radiotherapy, effective rHuKGF therapy schedules should include administration before the onset of ulcerative mucositis...