Gene Cutler

Summary

Affiliation: Amgen Inc
Country: USA

Publications

  1. ncbi Significant gene content variation characterizes the genomes of inbred mouse strains
    Gene Cutler
    Lead Discovery, Amgen, South San Francisco, California 94080, USA
    Genome Res 17:1743-54. 2007
  2. ncbi Copy number variation in the mouse genome: implications for the mouse as a model organism for human disease
    G Cutler
    Lead Discovery, Amgen, South San Francisco, CA, USA
    Cytogenet Genome Res 123:297-306. 2008
  3. ncbi Identification of transcriptional networks responding to pyrroloquinoline quinone dietary supplementation and their influence on thioredoxin expression, and the JAK/STAT and MAPK pathways
    Eskouhie Tchaparian
    Department of Nutrition, University of California Davis, 95616, USA
    Biochem J 429:515-26. 2010
  4. ncbi Multiclass cancer classification and biomarker discovery using GA-based algorithms
    Jane Jijun Liu
    Tularik Inc, South San Francisco, CA 94080, USA
    Bioinformatics 21:2691-7. 2005

Collaborators

  • Eskouhie Tchaparian
  • Jane Jijun Liu
  • Liangbiao Chen
  • Sihua Peng
  • Xuefeng Bruce Ling
  • Zheng Pan
  • Tim Hoey
  • Wuxiong Li

Detail Information

Publications4

  1. ncbi Significant gene content variation characterizes the genomes of inbred mouse strains
    Gene Cutler
    Lead Discovery, Amgen, South San Francisco, California 94080, USA
    Genome Res 17:1743-54. 2007
    ..Using a whole-genome association analysis, we demonstrate that complex multigenic phenotypes, such as food intake, can be associated with specific copy number changes...
  2. ncbi Copy number variation in the mouse genome: implications for the mouse as a model organism for human disease
    G Cutler
    Lead Discovery, Amgen, South San Francisco, CA, USA
    Cytogenet Genome Res 123:297-306. 2008
    ..These genetic differences can inform us about the history of a population or species, enlighten us on gene function, and guide our selection of a model system for the study of human disease...
  3. ncbi Identification of transcriptional networks responding to pyrroloquinoline quinone dietary supplementation and their influence on thioredoxin expression, and the JAK/STAT and MAPK pathways
    Eskouhie Tchaparian
    Department of Nutrition, University of California Davis, 95616, USA
    Biochem J 429:515-26. 2010
    ..Collectively, the results provide a mechanistic basis for previous functional observations associated with PQQ deficiency or PQQ administered in pharmacological amounts...
  4. ncbi Multiclass cancer classification and biomarker discovery using GA-based algorithms
    Jane Jijun Liu
    Tularik Inc, South San Francisco, CA 94080, USA
    Bioinformatics 21:2691-7. 2005
    ..With this approach, we believe that microarray-based multiclass molecular analysis can be an effective tool for cancer biomarker discovery and subsequent molecular cancer diagnosis...