M Thun

Summary

Affiliation: American Cancer Society
Country: USA

Publications

  1. pmc Genetic variation in candidate obesity genes ADRB2, ADRB3, GHRL, HSD11B1, IRS1, IRS2, and SHC1 and risk for breast cancer in the Cancer Prevention Study II
    Heather Spencer Feigelson
    Department of Epidemiology and Surveillance Research, American Cancer Society, Williams Street, NW, Atlanta, Georgia 30303 1002, USA
    Breast Cancer Res 10:R57. 2008
  2. pmc Recent trends in breast cancer incidence rates by age and tumor characteristics among U.S. women
    Ahmedin Jemal
    Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Rd, NE, Atlanta, GA 30329, USA
    Breast Cancer Res 9:R28. 2007
  3. pmc Lung cancer occurrence in never-smokers: an analysis of 13 cohorts and 22 cancer registry studies
    Michael J Thun
    American Cancer Society, Atlanta, Georgia, USA
    PLoS Med 5:e185. 2008
  4. pmc When truth is unwelcome: the first reports on smoking and lung cancer
    Michael J Thun
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30329 4251, USA
    Bull World Health Organ 83:144-5. 2005
  5. ncbi request reprint Tobacco use and cancer: an epidemiologic perspective for geneticists
    Michael J Thun
    American Cancer Society, Department of Epidemiology and Surveillance Research, 1599 Clifton Road, Atlanta, Georgia, GA 30329 4251, USA
    Oncogene 21:7307-25. 2002
  6. ncbi request reprint Cigarette smoking and changes in the histopathology of lung cancer
    M J Thun
    Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30329 4251, USA
    J Natl Cancer Inst 89:1580-6. 1997
  7. ncbi request reprint Lung cancer death rates in lifelong nonsmokers
    Michael J Thun
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30229 4251, USA
    J Natl Cancer Inst 98:691-9. 2006
  8. ncbi request reprint Pharmacologic effects of NSAIDs and implications for the risks and benefits of long-term prophylactic use of aspirin to prevent cancer
    Michael J Thun
    Epidemiology and Surveillance Research, American Cancer Society, NW, Atlanta, GA 30303 1002, USA
    Recent Results Cancer Res 181:215-21. 2009
  9. ncbi request reprint Nonsteroidal anti-inflammatory drugs as anticancer agents: mechanistic, pharmacologic, and clinical issues
    Michael J Thun
    Department of Epidemiology and Surveillance Research, American Cancer Society, National Home Office, Atlanta, GA 30329 4251, USA
    J Natl Cancer Inst 94:252-66. 2002
  10. pmc Health impact of "reduced yield" cigarettes: a critical assessment of the epidemiological evidence
    M J Thun
    American Cancer Society, Atlanta, Georgia 30329 4251, USA
    Tob Control 10:i4-11. 2001

Research Grants

Detail Information

Publications95

  1. pmc Genetic variation in candidate obesity genes ADRB2, ADRB3, GHRL, HSD11B1, IRS1, IRS2, and SHC1 and risk for breast cancer in the Cancer Prevention Study II
    Heather Spencer Feigelson
    Department of Epidemiology and Surveillance Research, American Cancer Society, Williams Street, NW, Atlanta, Georgia 30303 1002, USA
    Breast Cancer Res 10:R57. 2008
    ..Obesity has consistently been associated with postmenopausal breast cancer risk. Proteins that are secreted by adipose tissue or are involved in regulating body mass may play a role in breast tumor development...
  2. pmc Recent trends in breast cancer incidence rates by age and tumor characteristics among U.S. women
    Ahmedin Jemal
    Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Rd, NE, Atlanta, GA 30329, USA
    Breast Cancer Res 9:R28. 2007
    ....
  3. pmc Lung cancer occurrence in never-smokers: an analysis of 13 cohorts and 22 cancer registry studies
    Michael J Thun
    American Cancer Society, Atlanta, Georgia, USA
    PLoS Med 5:e185. 2008
    ..Better information on lung cancer occurrence in lifelong nonsmokers is needed to understand gender and racial disparities and to examine how factors other than active smoking influence risk in different time periods and geographic regions...
  4. pmc When truth is unwelcome: the first reports on smoking and lung cancer
    Michael J Thun
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30329 4251, USA
    Bull World Health Organ 83:144-5. 2005
  5. ncbi request reprint Tobacco use and cancer: an epidemiologic perspective for geneticists
    Michael J Thun
    American Cancer Society, Department of Epidemiology and Surveillance Research, 1599 Clifton Road, Atlanta, Georgia, GA 30329 4251, USA
    Oncogene 21:7307-25. 2002
    ....
  6. ncbi request reprint Cigarette smoking and changes in the histopathology of lung cancer
    M J Thun
    Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30329 4251, USA
    J Natl Cancer Inst 89:1580-6. 1997
    ..g., the adoption of filtertips), or changes in smoking practices. We examined data from the Connecticut Tumor Registry and two American Cancer Society studies to explore these possibilities...
  7. ncbi request reprint Lung cancer death rates in lifelong nonsmokers
    Michael J Thun
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30229 4251, USA
    J Natl Cancer Inst 98:691-9. 2006
    ..Such data are needed to quantify the risks associated with smoking and to understand racial and sex disparities and temporal trends that are due to factors other than active smoking...
  8. ncbi request reprint Pharmacologic effects of NSAIDs and implications for the risks and benefits of long-term prophylactic use of aspirin to prevent cancer
    Michael J Thun
    Epidemiology and Surveillance Research, American Cancer Society, NW, Atlanta, GA 30303 1002, USA
    Recent Results Cancer Res 181:215-21. 2009
    ..A singular advantage of aspirin over all other NSAIDs is the potential to combine reduced risk of certain cancers with cardiovascular benefit. However, many elements that are needed to achieve this remain unresolved...
  9. ncbi request reprint Nonsteroidal anti-inflammatory drugs as anticancer agents: mechanistic, pharmacologic, and clinical issues
    Michael J Thun
    Department of Epidemiology and Surveillance Research, American Cancer Society, National Home Office, Atlanta, GA 30329 4251, USA
    J Natl Cancer Inst 94:252-66. 2002
    ..Finally, we suggest research opportunities that may help to accelerate the future clinical application of NSAIDs for cancer prevention or treatment...
  10. pmc Health impact of "reduced yield" cigarettes: a critical assessment of the epidemiological evidence
    M J Thun
    American Cancer Society, Atlanta, Georgia 30329 4251, USA
    Tob Control 10:i4-11. 2001
    ..Tobacco control policies should not allow changes in cigarette design to subvert or distract from interventions proven to reduce the prevalence, intensity, and duration of smoking...
  11. pmc Epidemiologic studies of fatal and nonfatal cardiovascular disease and ETS exposure from spousal smoking
    M Thun
    American Cancer Society, Atlanta, Georgia 30329, USA
    Environ Health Perspect 107:841-6. 1999
    ..The evidence linking heart disease and ETS exposure from a spouse has become substantially stronger since OSHA first proposed including heart disease in its risk assessment of ETS in 1994...
  12. ncbi request reprint Smoking vs other risk factors as the cause of smoking-attributable deaths: confounding in the courtroom
    M J Thun
    American Cancer Society, 1599 Clifton Rd NE, Atlanta, GA 30329 4251, USA
    JAMA 284:706-12. 2000
    ..The tobacco industry has criticized the surgeon general's estimates because they do not control for the lower educational and socioeconomic status of modern-day smokers...
  13. doi request reprint An overview of the cancer burden for primary care physicians
    Michael Thun
    Department of Epidemiology, American Cancer Society, 250 Williams Street, N W, Atlanta, GA 30303 1002, USA
    Prim Care 36:439-54. 2009
    ....
  14. ncbi request reprint Annual report to the nation on the status of cancer, 1975-2000, featuring the uses of surveillance data for cancer prevention and control
    Hannah K Weir
    Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    J Natl Cancer Inst 95:1276-99. 2003
    ..This report updates statistics on lung, female breast, prostate, and colorectal cancers and highlights the uses of selected surveillance data to assist development of state-based cancer control plans...
  15. ncbi request reprint Dietary glycemic index, glycemic load, and risk of incident breast cancer in postmenopausal women
    Carolyn R Jonas
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, Georgia 30329 4251, USA
    Cancer Epidemiol Biomarkers Prev 12:573-7. 2003
    ..Future evaluations of glycemic index and breast cancer risk may be strengthened by longer follow-up, more complete dietary information, and measurement of plasma insulin and IGF-I levels...
  16. ncbi request reprint Cancer mortality in the United States by education level and race
    Jessica D Albano
    Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Rd, Atlanta, GA 30329, USA
    J Natl Cancer Inst 99:1384-94. 2007
    ..We examined relationships among race, education level, and mortality from cancers of the lung, breast, prostate, colon and rectum, and all sites combined in contemporary US vital statistics...
  17. ncbi request reprint Jewish ethnicity and prostate cancer mortality in two large US cohorts
    Carmen Rodriguez
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30329 4251, USA
    Cancer Causes Control 13:271-7. 2002
    ..To investigate prospectively the relationship between Jewish ethnicity and prostate cancer mortality...
  18. ncbi request reprint Vitamin C, vitamin E, and multivitamin supplement use and stomach cancer mortality in the Cancer Prevention Study II cohort
    Eric J Jacobs
    Department of Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road NE, Atlanta, GA 30329 4251, USA
    Cancer Epidemiol Biomarkers Prev 11:35-41. 2002
    ..Our results do not rule out effects of vitamin supplementation in areas in which stomach cancer rates are high and stomach cancer etiology may differ...
  19. ncbi request reprint Cancer statistics for Hispanics, 2003
    Kathryn O'Brien
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA, USA
    CA Cancer J Clin 53:208-26. 2003
    ....
  20. ncbi request reprint Meat consumption and risk of colorectal cancer
    Ann Chao
    Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30329 4251, USA
    JAMA 293:172-82. 2005
    ..Consumption of red and processed meat has been associated with colorectal cancer in many but not all epidemiological studies; few studies have examined risk in relation to long-term meat intake or the association of meat with rectal cancer...
  21. doi request reprint Cancer statistics, 2008
    Ahmedin Jemal
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA, USA
    CA Cancer J Clin 58:71-96. 2008
    ..Further progress can be accelerated by supporting new discoveries and by applying existing cancer control knowledge across all segments of the population...
  22. ncbi request reprint Lung cancer mortality rates in birth cohorts in the United States from 1960 to 1994
    D M Mannino
    Air Pollution and Respiratory Health Branch, Division of Environmental Hazards and Health Effects, National Center for Environmental Health NCEH, CDC, 1600 Clifton Road, M S E 17, 30333, Atlanta, GA, USA
    Lung Cancer 31:91-9. 2001
    ..Changes in cigarette design that have greatly reduced tar yields have a relatively small effect compared with that of people's smoking status and duration of smoking...
  23. ncbi request reprint Two large prospective studies of mortality among men who use snuff or chewing tobacco (United States)
    S Jane Henley
    Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road NE, Atlanta, GA 30329, USA
    Cancer Causes Control 16:347-58. 2005
    ..Few prospective studies have examined the health risks associated with use of snuff and chewing tobacco...
  24. ncbi request reprint Cancer statistics, 2007
    Ahmedin Jemal
    Cancer Occurrence, Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA, USA
    CA Cancer J Clin 57:43-66. 2007
    ..Further progress can be accelerated by supporting new discoveries and by applying existing cancer control knowledge across all segments of the population...
  25. ncbi request reprint Cancer statistics for African Americans
    Asma Ghafoor
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA, USA
    CA Cancer J Clin 52:326-41. 2002
    ..The extent to which these disparities reflect unequal access to health care versus other factors is an active area of research...
  26. ncbi request reprint A common 8q24 variant in prostate and breast cancer from a large nested case-control study
    Fredrick R Schumacher
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Cancer Res 67:2951-6. 2007
    ..590). Although the gene responsible has yet to be identified, the validation of this marker in this large sample of prostate cancer cases leaves little room for the possibility of a false-positive result...
  27. ncbi request reprint Cancer statistics, 2005
    Ahmedin Jemal
    Department of Epidemiology and Research Surveillance, American Cancer Society, Atlanta, GA, USA
    CA Cancer J Clin 55:10-30. 2005
    ..Progress in reducing the burden of suffering and death from cancer can be accelerated by applying existing cancer control knowledge across all segments of the population...
  28. ncbi request reprint A national framework for cancer surveillance in the United States
    Phyllis A Wingo
    Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Cancer Causes Control 16:151-70. 2005
    ..Implementation of the framework will require long-term, extensive coordination and cooperation among these major cancer surveillance organizations...
  29. ncbi request reprint Diet Quality Index as a predictor of short-term mortality in the American Cancer Society Cancer Prevention Study II Nutrition Cohort
    Jennifer D Seymour
    Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA, USA
    Am J Epidemiol 157:980-8. 2003
    ..31), and confidence intervals were wide, generally including 1.0. DQI was unrelated to cancer mortality. As currently constructed, the DQI may have limited ability to predict mortality...
  30. pmc Tobacco-related disease mortality among men who switched from cigarettes to spit tobacco
    S Jane Henley
    Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road, NE, Atlanta, GA 30329, USA
    Tob Control 16:22-8. 2007
    ....
  31. doi request reprint A prospective study of waist circumference and body mass index in relation to colorectal cancer incidence
    Yiting Wang
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30303 1002, USA
    Cancer Causes Control 19:783-92. 2008
    ..To study the association between waist circumference and colorectal cancer, and whether it is independent of body mass index (BMI)...
  32. ncbi request reprint Cancer statistics, 2003
    Ahmedin Jemal
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA, USA
    CA Cancer J Clin 53:5-26. 2003
    ..In spite of the continued decline in cancer death rates in the most recent time period, the total number of recorded cancer deaths in the United States continues to increase slightly due to the aging and expanding population...
  33. ncbi request reprint Calcium, vitamin D, dairy products, and risk of colorectal cancer in the Cancer Prevention Study II Nutrition Cohort (United States)
    Marjorie L McCullough
    Epidemiology and Surveillance Research Department, American Cancer Society, 1599 Clifton Rd NE, Atlanta GA, 30309 USA
    Cancer Causes Control 14:1-12. 2003
    ..Calcium, vitamin D, and dairy product intake may reduce the risk of colorectal cancer. We therefore examined the association between these factors and risk of colorectal cancer in a large prospective cohort of United States men and women...
  34. ncbi request reprint Body mass index, height, and postmenopausal breast cancer mortality in a prospective cohort of US women
    Jennifer M Petrelli
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30329, USA
    Cancer Causes Control 13:325-32. 2002
    ....
  35. ncbi request reprint Cancer statistics, 2006
    Ahmedin Jemal
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA, USA
    CA Cancer J Clin 56:106-30. 2006
    ..Progress in reducing the burden of suffering and death from cancer can be accelerated by applying existing cancer control knowledge across all segments of the population...
  36. ncbi request reprint Amount, type, and timing of recreational physical activity in relation to colon and rectal cancer in older adults: the Cancer Prevention Study II Nutrition Cohort
    Ann Chao
    Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road Northeast, Atlanta, GA 30329 4251, USA
    Cancer Epidemiol Biomarkers Prev 13:2187-95. 2004
    ....
  37. pmc Case studies in international tobacco surveillance: cigarette smuggling in Brazil
    O Shafey
    Epidemiology and Surveillance Research, American Cancer Society, Atlanta, Georgia 30329 4251, USA
    Tob Control 11:215-9. 2002
    ..This article is the first in a series of international case studies developed by the American Cancer Society to illustrate use of publicly available surveillance data for regional tobacco control...
  38. pmc Widening of socioeconomic inequalities in U.S. death rates, 1993-2001
    Ahmedin Jemal
    Epidemiology and Surveillance Research, American Cancer Society, Atlanta, Georgia, United States of America
    PLoS ONE 3:e2181. 2008
    ..S., largely because cardiovascular death rates decreased more slowly in lower than in higher socioeconomic groups. However, no studies have examined trends in inequalities using recent US national data...
  39. doi request reprint Postmenopausal hormone therapy and lung cancer risk in the cancer prevention study II nutrition cohort
    Carmen Rodriguez
    Epidemiology and Surveillance Research, American Cancer Society, National Home Office, 250 Williams Street Northwest, Atlanta, GA 30303, USA
    Cancer Epidemiol Biomarkers Prev 17:655-60. 2008
    ..Most of these studies, however, have had limited ability to control rigorously for cigarette smoking or to examine risk separately by smoking status...
  40. pmc Vitamin D pathway gene polymorphisms, diet, and risk of postmenopausal breast cancer: a nested case-control study
    Marjorie L McCullough
    Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road NE, Atlanta, GA 30329, USA
    Breast Cancer Res 9:R9. 2007
    ..Whether risk is influenced by polymorphisms in other vitamin D metabolism genes and whether calcium or vitamin D intake modifies risk by genotype have not been evaluated...
  41. doi request reprint Cancer occurrence
    Ahmedin Jemal
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA, USA
    Methods Mol Biol 471:3-29. 2009
    ..The variation according to risk factors provides strong evidence that much of cancer is caused by environmental factors and is potentially avoidable...
  42. doi request reprint Cancer statistics, 2009
    Ahmedin Jemal
    Cancer Surveillance, Surveillance and Health Policy Research, American Cancer Society, Atlanta, Georgia 30303 1002, USA
    CA Cancer J Clin 59:225-49. 2009
    ..Further progress can be accelerated by applying existing cancer control knowledge across all segments of the population and by supporting new discoveries in cancer prevention, early detection, and treatment...
  43. ncbi request reprint Body mass index, weight change, and risk of prostate cancer in the Cancer Prevention Study II Nutrition Cohort
    Carmen Rodriguez
    Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road Northeast, Atlanta, GA 30329 4251, USA
    Cancer Epidemiol Biomarkers Prev 16:63-9. 2007
    ..Obesity has been associated with aggressive prostate cancer. The extent of this association, which varies by stage and grade, remains unclear. The role of recent weight change had not been previously examined...
  44. ncbi request reprint A large cohort study of long-term daily use of adult-strength aspirin and cancer incidence
    Eric J Jacobs
    Department of Epidemiology and Surveillance Research, American Cancer Society, National Home Office, 1599 Clifton Rd NE, Atlanta, GA 30329, USA
    J Natl Cancer Inst 99:608-15. 2007
    ..However, the potential effect of long-term daily use of higher doses of aspirin on cancer incidence remains uncertain...
  45. pmc No association of single nucleotide polymorphisms in one-carbon metabolism genes with prostate cancer risk
    Victoria L Stevens
    Epidemiology and Surveillance Research, American Cancer Society, 250 Williams Street, Northwest, Atlanta, GA 30303 1002, USA
    Cancer Epidemiol Biomarkers Prev 17:3612-4. 2008
    ..Thus, our findings do not support the hypothesis that common genetic variation in one-carbon metabolism genes influences prostate cancer risk...
  46. pmc Nicotinic receptor gene variants influence susceptibility to heavy smoking
    Victoria L Stevens
    Department of Epidemiology and Surveillance Research, American Cancer Society, 250 Williams Street Northwest, Atlanta, GA 30303 1002, USA
    Cancer Epidemiol Biomarkers Prev 17:3517-25. 2008
    ..Our findings identify two loci in the CHRNA5-CHRNA3-CHRNB4 gene cluster that predict smoking behavior and provide strong evidence for the involvement of the alpha5 nicotinic receptor in heavy smoking...
  47. ncbi request reprint A prospective study of fruits, vegetables, and risk of endometrial cancer
    Marjorie L McCullough
    Epidemiology and Surveillance Research Department, American Cancer Society, Atlanta, GA 30303 1002, USA
    Am J Epidemiol 166:902-11. 2007
    ..03, p-trend = 0.11) or vegetable (RR = 0.80, 95% CI: 0.57, 1.13; p-interaction = 0.01, p-trend = 0.29) consumption. This prospective study does not support an association between vegetable or fruit consumption and endometrial cancer...
  48. pmc IGF-1, IGFBP-1, and IGFBP-3 polymorphisms predict circulating IGF levels but not breast cancer risk: findings from the Breast and Prostate Cancer Cohort Consortium (BPC3)
    Alpa V Patel
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, Georgia, United States of America
    PLoS ONE 3:e2578. 2008
    ..In summary, the impact of genetic variation in IGF1 and IGFBP3 on circulating IGF levels does not appear to substantially influence breast cancer risk substantially among primarily Caucasian postmenopausal women...
  49. pmc Leisure time spent sitting in relation to total mortality in a prospective cohort of US adults
    Alpa V Patel
    Epidemiology Research Program, American Cancer Society, 250 Williams Street NW, Atlanta, GA 30303, USA
    Am J Epidemiol 172:419-29. 2010
    ..The time spent sitting was independently associated with total mortality, regardless of physical activity level. Public health messages should include both being physically active and reducing time spent sitting...
  50. ncbi request reprint Cholesterol-lowering drugs and advanced prostate cancer incidence in a large U.S. cohort
    Eric J Jacobs
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30303 1002, USA
    Cancer Epidemiol Biomarkers Prev 16:2213-7. 2007
    ..Long-duration statin use was associated with substantially reduced risk of advanced prostate cancer in a recent large prospective study...
  51. doi request reprint Body mass and endometrial cancer risk by hormone replacement therapy and cancer subtype
    Marjorie L McCullough
    Epidemiology and Surveillance Research, American Cancer Society, 250 Williams Street, Atlanta, GA 30303 1002, USA
    Cancer Epidemiol Biomarkers Prev 17:73-9. 2008
    ..87; 95% CI, 1.59-5.16). The increased risk of endometrial cancer across the range of BMI in women who never used postmenopausal HT stresses the need to prevent both overweight and obesity in women...
  52. doi request reprint Temporal trends in breast cancer mortality by state and race
    Carol DeSantis
    Epidemiology and Surveillance Research, American Cancer Society, 250 Williams Street, NW, Atlanta, GA, 30303, USA
    Cancer Causes Control 19:537-45. 2008
    ..To examine how temporal trends in age-standardized female breast cancer death rates vary by state and race...
  53. pmc U.S. congressional district cancer death rates
    Yongping Hao
    American Cancer Society, 1599 Clifton Road, NE, Atlanta, Georgia, USA
    Int J Health Geogr 5:28. 2006
    ..These rates may be useful in communicating to legislators and policy makers about the cancer burden and potential impact of cancer control in their jurisdictions...
  54. ncbi request reprint Transforming growth factor beta receptor type I and transforming growth factor beta1 polymorphisms are not associated with postmenopausal breast cancer
    Heather Spencer Feigelson
    Department of Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road Northeast, Atlanta, GA 30329, USA
    Cancer Epidemiol Biomarkers Prev 15:1236-7. 2006
  55. ncbi request reprint Risk factors for fatal breast cancer in African-American women and White women in a large US prospective cohort
    Marjorie L McCullough
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30329 4251, USA
    Am J Epidemiol 162:734-42. 2005
    ..With few exceptions, established breast cancer risk factors were similarly associated with risk of death from breast cancer among African-American women and White women...
  56. ncbi request reprint Long-term trends in cancer mortality in the United States, 1930-1998
    Phyllis A Wingo
    Department of Epidemiology and Surveillance Research, American Cancer Society, National Home Office, Atlanta, Georgia, USA
    Cancer 97:3133-275. 2003
    ..S. Department of Health and Human Services to adopt the 2000 U.S. standard population for the age adjustment of death rates prompted the American Cancer Society to update historical cancer mortality statistics using the new standard...
  57. ncbi request reprint Recreational physical activity and risk of prostate cancer in a large cohort of U.S. men
    Alpa V Patel
    Department of Epidemiology and Surveillance Research, American Cancer Society, National Home Office, 1599 Clifton Road Northeast, Atlanta, GA 30329 4251, USA
    Cancer Epidemiol Biomarkers Prev 14:275-9. 2005
    ....
  58. ncbi request reprint No association between the progesterone receptor gene +331G/A polymorphism and breast cancer
    Heather Spencer Feigelson
    Department of Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road NE, Atlanta GA 30309, USA
    Cancer Epidemiol Biomarkers Prev 13:1084-5. 2004
  59. ncbi request reprint Under-use of smoking-cessation treatments: results from the National Health Interview Survey, 2000
    Vilma E Cokkinides
    Epidemiology and Surveillance Research, American Cancer Society, Atlanta, Georgia, USA
    Am J Prev Med 28:119-22. 2005
    ..To describe the use of treatment for tobacco dependence in relation to insurance status and advice from a healthcare provider in a population-based national sample interviewed in 2000...
  60. ncbi request reprint Calcium, dairy products, and risk of prostate cancer in a prospective cohort of United States men
    Carmen Rodriguez
    Epidemiology and Surveillance Research Department, American Cancer Society, Atlanta, Georgia 30309, USA
    Cancer Epidemiol Biomarkers Prev 12:597-603. 2003
    ..1, 95% CI = 1.3-3.4 >or=2000 mg/day of dietary calcium, P trend = 0.04). Our results support the hypothesis that very high calcium intake, above the recommended intake for men, may modestly increase risk of prostate cancer...
  61. ncbi request reprint Recreational physical activity and risk of postmenopausal breast cancer in a large cohort of US women
    Alpa V Patel
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30329 4251, USA
    Cancer Causes Control 14:519-29. 2003
    ..Our findings are consistent with other studies that show lower risk of postmenopausal breast cancer associated with regular physical activity...
  62. ncbi request reprint Lung cancer trends in young adults: an early indicator of progress in tobacco control (United States)
    Ahmedin Jemal
    Epidemiology and Surveillance Research, American Cancer Society, Atlanta 30329, USA
    Cancer Causes Control 14:579-85. 2003
    ..We evaluated state trends in lung cancer death rates among young adults in relation to an index of state tobacco control activities and conventional indices of current smoking and cessation...
  63. ncbi request reprint Aspirin use and pancreatic cancer mortality in a large United States cohort
    Eric J Jacobs
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30329, USA
    J Natl Cancer Inst 96:524-8. 2004
    ..Results from some epidemiologic studies have suggested that aspirin use may reduce risk of pancreatic cancer, but the evidence remains limited...
  64. ncbi request reprint Obesity and cancer
    Eugenia E Calle
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30329, USA
    Oncogene 23:6365-78. 2004
    ..If the correlation between obesity and cancer mortality is entirely causal, we estimate that overweight and obesity now account for one in seven of cancer deaths in men and one in five in women in the US...
  65. ncbi request reprint Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults
    Eugenia E Calle
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta 30329, USA
    N Engl J Med 348:1625-38. 2003
    ..The influence of excess body weight on the risk of death from cancer has not been fully characterized...
  66. ncbi request reprint Dairy, calcium, and vitamin D intake and postmenopausal breast cancer risk in the Cancer Prevention Study II Nutrition Cohort
    Marjorie L McCullough
    Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road Northeast, Atlanta, GA 30329 4251, USA
    Cancer Epidemiol Biomarkers Prev 14:2898-904. 2005
    ..Calcium, vitamin D, and dairy products are highly correlated factors, each with potential roles in breast carcinogenesis. Few prospective studies have examined these relationships in postmenopausal women...
  67. ncbi request reprint Adult weight gain and histopathologic characteristics of breast cancer among postmenopausal women
    Heather Spencer Feigelson
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, Georgia 30329, USA
    Cancer 107:12-21. 2006
    ..Although the link between postmenopausal breast cancer and adiposity is well established, the association between weight gain and specific histopathologic characteristics of breast carcinoma has not been studied carefully...
  68. ncbi request reprint Meat consumption among Black and White men and risk of prostate cancer in the Cancer Prevention Study II Nutrition Cohort
    Carmen Rodriguez
    Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road Northeast, Atlanta, Georgia 30329 4251, USA
    Cancer Epidemiol Biomarkers Prev 15:211-6. 2006
    ..7; 95% CI, 1.3-5.3 for highest versus lowest quartile; P(trend) = 0.008). This study suggests that high consumption of cooked processed meats may contribute to prostate cancer risk among Black men in the United States...
  69. ncbi request reprint Body mass index, height, and the risk of ovarian cancer mortality in a prospective cohort of postmenopausal women
    Carmen Rodriguez
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, Georgia 30329 4251, USA
    Cancer Epidemiol Biomarkers Prev 11:822-8. 2002
    ..The 36% increase in risk associated with obesity among women who had never used postmenopausal estrogens may have important public health implications because obesity is a growing problem in the United States...
  70. ncbi request reprint Haplotype analysis of the HSD17B1 gene and risk of breast cancer: a comprehensive approach to multicenter analyses of prospective cohort studies
    Heather Spencer Feigelson
    Department of Epidemiology and Surveillance Research, American Cancer Society, National Home Office, Atlanta, Georgia 30329, USA
    Cancer Res 66:2468-75. 2006
    ..Although the probability that these ER-negative findings are false-positive results is high, these findings were consistent across each cohort examined and warrant further study...
  71. ncbi request reprint Intentional weight loss and mortality among overweight individuals with diabetes
    D F Williamson
    Division of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, Georgia 30341 3717, USA
    Diabetes Care 23:1499-504. 2000
    ..To estimate the effect of intentional weight loss on mortality in overweight individuals with diabetes...
  72. ncbi request reprint Cancer statistics, 2001
    R T Greenlee
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA, USA
    CA Cancer J Clin 51:15-36. 2001
    ..The disparity in survival reflects both diagnosis of cancer at later disease stages, and poorer survival within each stage of diagnosis...
  73. pmc Benefits of smoking cessation for longevity
    Donald H Taylor
    Center for Health Policy, Law and Management, Terry Sanford Institute of Public Policy Studies, Duke University, Durham, NC 27708, USA
    Am J Public Health 92:990-6. 2002
    ..This study determined the life extension obtained from stopping smoking at various ages...
  74. pmc Recreational physical activity and risk of Parkinson's disease
    Evan L Thacker
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
    Mov Disord 23:69-74. 2008
    ..Our results may be explained either by a reduction in PD risk through moderate to vigorous activity, or by decreased baseline recreational activity due to preclinical PD...
  75. doi request reprint Diet and amyotrophic lateral sclerosis
    Natalia Morozova
    Departments of Nutrition, Harvard School of Public Health, Boston, MA 02215, USA
    Epidemiology 19:324-37. 2008
    ..Several dietary factors have been associated with risk of amyotrophic lateral sclerosis (ALS) in case-control studies, but no prospective studies have investigated diet and ALS...
  76. pmc Cigarette tar yields in relation to mortality from lung cancer in the cancer prevention study II prospective cohort, 1982-8
    Jeffrey E Harris
    Department of Economics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    BMJ 328:72. 2004
    ..To assess the risk of lung cancer in smokers of medium tar filter cigarettes compared with smokers of low tar and very low tar filter cigarettes...
  77. ncbi request reprint Relationships between polymorphisms in NOS3 and MPO genes, cigarette smoking and risk of post-menopausal breast cancer
    Jun Yang
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Carcinogenesis 28:1247-53. 2007
    ....
  78. ncbi request reprint Annual report to the nation on the status of cancer, 1973-1999, featuring implications of age and aging on U.S. cancer burden
    Brenda K Edwards
    Division of Cancer Control and Population Sciences, National Cancer Institute, 6116 Executive Blvd, Suite 504 MSC 8315, Bethesda, MD 20892 8315, USA
    Cancer 94:2766-92. 2002
    ..This year's report contained a special feature focusing on implications of age and aging on the U.S. cancer burden...
  79. ncbi request reprint Lung cancer mortality is related to age in addition to duration and intensity of cigarette smoking: an analysis of CPS-I data
    James D Knoke
    Department of Family and Preventive Medicine, University of California at San Diego, 92108, USA
    Cancer Epidemiol Biomarkers Prev 13:949-57. 2004
    ..We reexamined these models using the American Cancer Society's Cancer Prevention Study I data that include a range of ages of initiation to assess the importance of an additional term for age...
  80. ncbi request reprint Genetic variability in iron-related oxidative stress pathways (Nrf2, NQ01, NOS3, and HO-1), iron intake, and risk of postmenopausal breast cancer
    Chi Chen Hong
    Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
    Cancer Epidemiol Biomarkers Prev 16:1784-94. 2007
    ....
  81. doi request reprint Multiple loci identified in a genome-wide association study of prostate cancer
    Gilles Thomas
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Nat Genet 40:310-5. 2008
    ..Our findings point to multiple loci with moderate effects associated with susceptibility to prostate cancer that, taken together, in the future may predict high risk in select individuals...
  82. ncbi request reprint A midpoint assessment of the American Cancer Society challenge goal to halve the U.S. cancer mortality rates between the years 1990 and 2015
    Tim Byers
    University of Colorado School of Medicine, Denver, Colorado 80045, USA
    Cancer 107:396-405. 2006
    ..S. to reduce cancer mortality rates 50% over the 25 years from 1990 to 2015. The current report is an analysis and commentary on progress toward that goal through 2002, the midpoint of the challenge period...
  83. pmc Consumption of dairy products and risk of Parkinson's disease
    Honglei Chen
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA
    Am J Epidemiol 165:998-1006. 2007
    ..8, 2.1). These data suggest that dairy consumption may increase the risk of Parkinson's disease, particularly in men. More studies are needed to further examine these findings and to explore underlying mechanisms...
  84. ncbi request reprint Lung cancer, smoke exposure, and sex
    Adi F Gazdar
    J Clin Oncol 25:469-71. 2007
  85. ncbi request reprint Genetic variation at the CYP19A1 locus predicts circulating estrogen levels but not breast cancer risk in postmenopausal women
    Christopher A Haiman
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90033, USA
    Cancer Res 67:1893-7. 2007
    ..Thus, although genetic variation in CYP19A1 produces measurable differences in estrogen levels among postmenopausal women, the magnitude of the change was insufficient to contribute detectably to breast cancer...
  86. ncbi request reprint Genome-wide association study of prostate cancer identifies a second risk locus at 8q24
    Meredith Yeager
    SAIC Frederick, National Cancer Institute NCI Frederick Cancer Research and Development Center, Frederick, Maryland 21702, USA
    Nat Genet 39:645-9. 2007
    ..We estimate that the population attributable risk of the new locus, marked by rs6983267, is higher than the locus marked by rs1447295 (21% versus 9%)...
  87. pmc Genetic variation in the HSD17B1 gene and risk of prostate cancer
    Peter Kraft
    Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS Genet 1:e68. 2005
    ..These results suggest that the germline variants in HSD17B1 characterized by these htSNPs do not substantially influence the risk of prostate cancer in U.S. and European whites...
  88. pmc A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer
    David J Hunter
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Nat Genet 39:870-4. 2007
    ..Our summary results from the GWAS are available online in a form that should speed the identification of additional risk loci...
  89. ncbi request reprint Sequence variants of estrogen receptor beta and risk of prostate cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium
    Yen Ching Chen
    Channing Laboratory, 181 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 16:1973-81. 2007
    ..Estrogen receptor beta (ESR2) may play a role in modulating prostate carcinogenesis through the regulation of genes related to cell proliferation and apoptosis...
  90. ncbi request reprint Vitamin E intake and risk of amyotrophic lateral sclerosis
    Alberto Ascherio
    Department of Nutrition, Harvard School of Public Health, 655 Huntington Avenue, Building 2, Boston, MA 02115, USA
    Ann Neurol 57:104-10. 2005
    ..004). In contrast, no significant associations were found for use of vitamin C or multivitamins. These results suggest that vitamin E supplementation could have a role in ALS prevention...
  91. ncbi request reprint Coffee consumption, gender, and Parkinson's disease mortality in the cancer prevention study II cohort: the modifying effects of estrogen
    Alberto Ascherio
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 160:977-84. 2004
    ..75, 2.30; p = 0.34) among users. These results suggest that caffeine reduces the risk of Parkinson's disease but that this hypothetical beneficial effect may be prevented by use of estrogen replacement therapy...
  92. ncbi request reprint A midpoint assessment of the American Cancer Society challenge goal to decrease cancer incidence by 25% between 1992 and 2015
    Rebecca L Sedjo
    Department of Preventive Medicine, University of Colorado Health Sciences Center, Aurora, CO, USA
    CA Cancer J Clin 57:326-40. 2007
    ....
  93. ncbi request reprint The change in excess risk of lung cancer attributable to smoking following smoking cessation: an examination of different analytic approaches using CPS-I data
    James D Knoke
    Department of Family and Preventive Medicine, University of California at San Diego, San Diego, CA, USA
    Cancer Causes Control 19:207-19. 2008
    ..This bias is termed the quitting ill effect...
  94. ncbi request reprint CYP17 genetic variation and risk of breast and prostate cancer from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3)
    Veronica Wendy Setiawan
    Department of Preventive Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Cancer Epidemiol Biomarkers Prev 16:2237-46. 2007
    ..Our findings do not support the hypothesis that common germ line variation in CYP17 makes a substantial contribution to postmenopausal breast or prostate cancer susceptibility...
  95. ncbi request reprint American Cancer Society Guidelines on Nutrition and Physical Activity for cancer prevention: reducing the risk of cancer with healthy food choices and physical activity
    Lawrence H Kushi
    Etiology and Prevention Research, Kaiser Permanente, Oakland, CA, USA
    CA Cancer J Clin 56:254-81; quiz 313-4. 2006
    ....

Research Grants2

  1. Breast & prostate cancer & hormone-related gene variants
    Michael Thun; Fiscal Year: 2006
    ..The ultimate goal is to provide the foundation for reducing the public health burden of these cancers. ..