Victoria L Stevens

Summary

Affiliation: American Cancer Society
Country: USA

Publications

  1. doi request reprint Genetic variation in the toll-like receptor gene cluster (TLR10-TLR1-TLR6) and prostate cancer risk
    Victoria L Stevens
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30303 1002, USA
    Int J Cancer 123:2644-50. 2008
  2. ncbi request reprint Weight cycling and mortality in a large prospective US study
    Victoria L Stevens
    Epidemiology Research Program, American Cancer Society, 250 Williams Street NW, Atlanta, GA 30303, USA
    Am J Epidemiol 175:785-92. 2012
  3. ncbi request reprint Body weight in early adulthood, adult weight gain, and risk of endometrial cancer in women not using postmenopausal hormones
    Victoria L Stevens
    Epidemiology Research Program, American Cancer Society, 250 Williams St, NW, Atlanta, GA, 30329, USA
    Cancer Causes Control 25:321-8. 2014
  4. doi request reprint Weight cycling and risk of endometrial cancer
    Victoria L Stevens
    Epidemiology Research Program, American Cancer Society, Atlanta, Georgia 30329, USA
    Cancer Epidemiol Biomarkers Prev 21:747-52. 2012
  5. pmc Nicotinic receptor gene variants influence susceptibility to heavy smoking
    Victoria L Stevens
    Department of Epidemiology and Surveillance Research, American Cancer Society, 250 Williams Street Northwest, Atlanta, GA 30303 1002, USA
    Cancer Epidemiol Biomarkers Prev 17:3517-25. 2008
  6. doi request reprint Paraoxonase 1 (PON1) polymorphisms and prostate cancer in the CPS-II Nutrition Cohort
    Victoria L Stevens
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30329, USA
    Prostate 68:1336-40. 2008
  7. pmc No association of single nucleotide polymorphisms in one-carbon metabolism genes with prostate cancer risk
    Victoria L Stevens
    Epidemiology and Surveillance Research, American Cancer Society, 250 Williams Street, Northwest, Atlanta, GA 30303 1002, USA
    Cancer Epidemiol Biomarkers Prev 17:3612-4. 2008
  8. pmc HNF1B and JAZF1 genes, diabetes, and prostate cancer risk
    Victoria L Stevens
    Department of Epidemiology, American Cancer Society, Atlanta, Georgia 30303 1002, USA
    Prostate 70:601-7. 2010
  9. ncbi request reprint Folate and other one-carbon metabolism-related nutrients and risk of postmenopausal breast cancer in the Cancer Prevention Study II Nutrition Cohort
    Victoria L Stevens
    American Cancer Society, Atlanta, GA 30303 1002, USA
    Am J Clin Nutr 91:1708-15. 2010
  10. doi request reprint High levels of folate from supplements and fortification are not associated with increased risk of colorectal cancer
    Victoria L Stevens
    Epidemiology Research Program, American Cancer Society, Atlanta, Georgia 30303 1002, USA
    Gastroenterology 141:98-105, 105.e1. 2011

Research Grants

Detail Information

Publications38

  1. doi request reprint Genetic variation in the toll-like receptor gene cluster (TLR10-TLR1-TLR6) and prostate cancer risk
    Victoria L Stevens
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30303 1002, USA
    Int J Cancer 123:2644-50. 2008
    ..55, 95% CI: 0.33, 0.90). Our study suggest that a common haplotype in the TLR10-TLR1-TLR6 gene cluster influences prostate cancer risk and clearly supports the need for further investigation of TLR genes in other populations...
  2. ncbi request reprint Weight cycling and mortality in a large prospective US study
    Victoria L Stevens
    Epidemiology Research Program, American Cancer Society, 250 Williams Street NW, Atlanta, GA 30303, USA
    Am J Epidemiol 175:785-92. 2012
    ..03, 95% CI: 0.89, 1.19 in men and HR = 0.99, 95% CI: 0.88, 1.12 in women). These results do not support an increased risk of mortality associated with weight cycling...
  3. ncbi request reprint Body weight in early adulthood, adult weight gain, and risk of endometrial cancer in women not using postmenopausal hormones
    Victoria L Stevens
    Epidemiology Research Program, American Cancer Society, 250 Williams St, NW, Atlanta, GA, 30329, USA
    Cancer Causes Control 25:321-8. 2014
    ..However, whether BMI measured in early adulthood and adult weight change are associated with endometrial cancer risk is less clear, particularly among nonusers of postmenopausal hormones (PMH)...
  4. doi request reprint Weight cycling and risk of endometrial cancer
    Victoria L Stevens
    Epidemiology Research Program, American Cancer Society, Atlanta, Georgia 30329, USA
    Cancer Epidemiol Biomarkers Prev 21:747-52. 2012
    ..Weight cycling, which consists of repeated cycles of weight loss followed by regain, occurs frequently in overweight and obese women. It is unclear whether weight cycling is associated with risk of endometrial cancer independent of BMI...
  5. pmc Nicotinic receptor gene variants influence susceptibility to heavy smoking
    Victoria L Stevens
    Department of Epidemiology and Surveillance Research, American Cancer Society, 250 Williams Street Northwest, Atlanta, GA 30303 1002, USA
    Cancer Epidemiol Biomarkers Prev 17:3517-25. 2008
    ..Our findings identify two loci in the CHRNA5-CHRNA3-CHRNB4 gene cluster that predict smoking behavior and provide strong evidence for the involvement of the alpha5 nicotinic receptor in heavy smoking...
  6. doi request reprint Paraoxonase 1 (PON1) polymorphisms and prostate cancer in the CPS-II Nutrition Cohort
    Victoria L Stevens
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30329, USA
    Prostate 68:1336-40. 2008
    ..PON1, which encodes paraoxonase 1, has two common, nonsynonymous SNPs that alter the activity of this enzyme and may influence cancer risk...
  7. pmc No association of single nucleotide polymorphisms in one-carbon metabolism genes with prostate cancer risk
    Victoria L Stevens
    Epidemiology and Surveillance Research, American Cancer Society, 250 Williams Street, Northwest, Atlanta, GA 30303 1002, USA
    Cancer Epidemiol Biomarkers Prev 17:3612-4. 2008
    ..Thus, our findings do not support the hypothesis that common genetic variation in one-carbon metabolism genes influences prostate cancer risk...
  8. pmc HNF1B and JAZF1 genes, diabetes, and prostate cancer risk
    Victoria L Stevens
    Department of Epidemiology, American Cancer Society, Atlanta, Georgia 30303 1002, USA
    Prostate 70:601-7. 2010
    ..Epidemiologic studies have shown that men with type II diabetes have a lower risk of prostate cancer than non-diabetic men. Recently, common variants in two genes, HNF1B and JAZF1, were found to be associated with both of these diseases...
  9. ncbi request reprint Folate and other one-carbon metabolism-related nutrients and risk of postmenopausal breast cancer in the Cancer Prevention Study II Nutrition Cohort
    Victoria L Stevens
    American Cancer Society, Atlanta, GA 30303 1002, USA
    Am J Clin Nutr 91:1708-15. 2010
    ..Epidemiologic studies of the association of folate intake with breast cancer risk have been inconclusive, and few have investigated how related nutrients modify this association...
  10. doi request reprint High levels of folate from supplements and fortification are not associated with increased risk of colorectal cancer
    Victoria L Stevens
    Epidemiology Research Program, American Cancer Society, Atlanta, Georgia 30303 1002, USA
    Gastroenterology 141:98-105, 105.e1. 2011
    ..There is evidence that consumption of high levels of folic acid, the form of folate used for fortification and in supplements, has different effects on biochemical pathways than natural folates and might promote carcinogenesis...
  11. ncbi request reprint Cryopreservation of whole blood samples collected in the field for a large epidemiologic study
    Victoria L Stevens
    Department of Epidemiology and Surveillance Research, American Cancer Society, 250 Williams Street, NW, Atlanta, GA 30303, USA
    Cancer Epidemiol Biomarkers Prev 16:2160-3. 2007
    ....
  12. ncbi request reprint Association of polymorphisms in one-carbon metabolism genes and postmenopausal breast cancer incidence
    Victoria L Stevens
    Department of Epidemiology and Surveillance Research, American Cancer Society, Northeastern, Atlanta, GA 30329, USA
    Cancer Epidemiol Biomarkers Prev 16:1140-7. 2007
    ..However, larger studies are needed to further examine gene/gene and gene/diet interactions in this pathway...
  13. ncbi request reprint Use of multivitamins and prostate cancer mortality in a large cohort of US men
    Victoria L Stevens
    Department of Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road NE, Atlanta, GA 30329, USA
    Cancer Causes Control 16:643-50. 2005
    ..To assess the association between the use of multivitamins and prostate cancer mortality...
  14. ncbi request reprint Folate nutrition and prostate cancer incidence in a large cohort of US men
    Victoria L Stevens
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30329, USA
    Am J Epidemiol 163:989-96. 2006
    ..Because the statistical power of the analysis with advanced prostate cancer was limited by the low number of cases, further study is needed to establish this association...
  15. ncbi request reprint Association of polymorphisms in the paraoxonase 1 gene with breast cancer incidence in the CPS-II Nutrition Cohort
    Victoria L Stevens
    Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road, Northeast, Atlanta, GA 30329, USA
    Cancer Epidemiol Biomarkers Prev 15:1226-8. 2006
    ..46; 95% CI, 1.39-4.36). These results suggest that genetic variation in PON1, particularly at the L55M SNP, may be associated with increased risk of breast cancer in postmenopausal women. Furthermore, NSAID use seems to modify this risk...
  16. ncbi request reprint Nested case-control study of energy regulation candidate gene single nucleotide polymorphisms and breast cancer
    Yiting Wang
    Department of Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road NE, Atlanta, Georgia, GA 30329 4251, USA
    Anticancer Res 27:589-93. 2007
    ..Accumulating evidence suggests that energy regulation, particularly insulin resistance, may influence breast cancer risk...
  17. doi request reprint Polymorphisms in angiogenesis-related genes and prostate cancer
    Eric J Jacobs
    Epidemiology and Surveillance Research, American Cancer Society, National Home Office, Atlanta, GA 30303 1002, USA
    Cancer Epidemiol Biomarkers Prev 17:972-7. 2008
    ..Potentially functional single nucleotide polymorphisms (SNP) in genes important in prostate angiogenesis (VEGF, HIF1A, and NOS3) have previously been associated with risk or severity of prostate cancer...
  18. pmc Serum 25-hydroxyvitamin D concentrations and postmenopausal breast cancer risk: a nested case control study in the Cancer Prevention Study-II Nutrition Cohort
    Marjorie L McCullough
    Epidemiology Research, American Cancer Society, 240 Williams Street, Atlanta, GA 30303 1002, USA
    Breast Cancer Res 11:R64. 2009
    ..Vitamin D has been hypothesized to prevent breast cancer through genomic and non-genomic actions in cell-cycle regulation...
  19. pmc Vitamin D pathway gene polymorphisms, diet, and risk of postmenopausal breast cancer: a nested case-control study
    Marjorie L McCullough
    Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road NE, Atlanta, GA 30329, USA
    Breast Cancer Res 9:R9. 2007
    ..Whether risk is influenced by polymorphisms in other vitamin D metabolism genes and whether calcium or vitamin D intake modifies risk by genotype have not been evaluated...
  20. pmc Genetic variation in candidate obesity genes ADRB2, ADRB3, GHRL, HSD11B1, IRS1, IRS2, and SHC1 and risk for breast cancer in the Cancer Prevention Study II
    Heather Spencer Feigelson
    Department of Epidemiology and Surveillance Research, American Cancer Society, Williams Street, NW, Atlanta, Georgia 30303 1002, USA
    Breast Cancer Res 10:R57. 2008
    ..Obesity has consistently been associated with postmenopausal breast cancer risk. Proteins that are secreted by adipose tissue or are involved in regulating body mass may play a role in breast tumor development...
  21. ncbi request reprint Transforming growth factor beta receptor type I and transforming growth factor beta1 polymorphisms are not associated with postmenopausal breast cancer
    Heather Spencer Feigelson
    Department of Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road Northeast, Atlanta, GA 30329, USA
    Cancer Epidemiol Biomarkers Prev 15:1236-7. 2006
  22. pmc Polymorphisms in the vascular endothelial growth factor gene and breast cancer in the Cancer Prevention Study II cohort
    Eric J Jacobs
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, Georgia, USA
    Breast Cancer Res 8:R22. 2006
    ..At least four polymorphisms in the VEGF gene have been associated with changes in VEGF expression levels: -2578C/A, -1154G/A and -634G/C are all located in the promoter region; and +936C/T is located in the 3'-untranslated region...
  23. ncbi request reprint Dairy, calcium, and vitamin D intake and postmenopausal breast cancer risk in the Cancer Prevention Study II Nutrition Cohort
    Marjorie L McCullough
    Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road Northeast, Atlanta, GA 30329 4251, USA
    Cancer Epidemiol Biomarkers Prev 14:2898-904. 2005
    ..Calcium, vitamin D, and dairy products are highly correlated factors, each with potential roles in breast carcinogenesis. Few prospective studies have examined these relationships in postmenopausal women...
  24. pmc One thousand genomes imputation in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium aggressive prostate cancer genome-wide association study
    Mitchell J Machiela
    Program in Molecular and Genetic Epidemiology, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Prostate 73:677-89. 2013
    ....
  25. pmc Replication of five prostate cancer loci identified in an Asian population--results from the NCI Breast and Prostate Cancer Cohort Consortium (BPC3)
    Sara Lindstrom
    Department of Epidemiology, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 21:212-6. 2012
    ..In this study, we attempt to replicate these five loci in a series of nested prostate cancer case-control studies of European ancestry...
  26. doi request reprint A large cohort study of long-term acetaminophen use and prostate cancer incidence
    Eric J Jacobs
    Epidemiology Research Program, American Cancer Society, National Home Office, Northwest Atlanta, GA 30303, USA
    Cancer Epidemiol Biomarkers Prev 20:1322-8. 2011
    ..Acetaminophen, a commonly used pain reliever, is not traditionally considered an NSAID but can have anti-inflammatory effects. Few studies have examined the association between long-term acetaminophen use and prostate cancer incidence...
  27. pmc Association of type 2 diabetes susceptibility variants with advanced prostate cancer risk in the Breast and Prostate Cancer Cohort Consortium
    Mitchell J Machiela
    Program in Molecular and Genetic Epidemiology, Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 176:1121-9. 2012
    ..These data suggest a shared genetic component between T2D and PCa and add to the evidence for an interrelation between these diseases...
  28. pmc Correlates of circulating 25-hydroxyvitamin D: Cohort Consortium Vitamin D Pooling Project of Rarer Cancers
    Marjorie L McCullough
    American Cancer Society, Atlanta, Georgia 30303 1002, USA
    Am J Epidemiol 172:21-35. 2010
    ..Correlates varied somewhat within season, race/ethnicity, and sex. These findings help identify persons at risk for low vitamin D status for both clinical and research purposes...
  29. doi request reprint Work schedule, sleep duration, insomnia, and risk of fatal prostate cancer
    Susan M Gapstur
    Epidemiology Research Program, American Cancer Society, Atlanta, Georgia Electronic address
    Am J Prev Med 46:S26-33. 2014
    ..However, evidence linking shift work and other circadian disruption factors to prostate cancer risk is limited...
  30. doi request reprint Plasma total, LDL, and HDL cholesterol and risk of aggressive prostate cancer in the Cancer Prevention Study II Nutrition Cohort
    Eric J Jacobs
    Epidemiology Research Program, American Cancer Society, National Home Office, 250 Williams Street, Atlanta, GA 30303 1002, USA
    Cancer Causes Control 23:1289-96. 2012
    ..We therefore examined associations of total, LDL, and HDL cholesterol concentrations with subsequent risk of aggressive prostate cancer within the Cancer Prevention Study II Nutrition Cohort...
  31. pmc SnoRNA U50 is a candidate tumor-suppressor gene at 6q14.3 with a mutation associated with clinically significant prostate cancer
    Xue Yuan Dong
    Winship Cancer Institute, Emory University School of Medicine, 1365 Clifton Road, Atlanta, GA 30322, USA
    Hum Mol Genet 17:1031-42. 2008
    ..9; 95% confidence interval 1.17-7.21). These findings establish snoRNA U50 as a reasonable candidate for the 6q tumor-suppressor gene in prostate cancer and likely in other types of cancers...
  32. ncbi request reprint No Association of Plasma Levels of Adiponectin and c-peptide with Risk of Aggressive Prostate Cancer in the Cancer Prevention Study II Nutrition Cohort
    Victoria L Stevens
    Authors Affiliation Epidemiology Research Program, American Cancer Society, Atlanta, Georgia
    Cancer Epidemiol Biomarkers Prev 23:890-2. 2014
    ..Results of some studies showed associations of circulating levels of adiponectin, insulin, and c-peptide (a marker of insulin secretion) with aggressive prostate cancer, but the size of these studies was limited...
  33. pmc A genome-wide association study identifies a novel susceptibility locus for renal cell carcinoma on 12p11.23
    Xifeng Wu
    Department of Epidemiology, Division of Cancer Prevention and Population Sciences, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Hum Mol Genet 21:456-62. 2012
    ..18 (95% CI: 1.12-1.25) for rs1049380. It has been recently identified that rs718314 in ITPR2 is associated with waist-hip ratio (WHR) phenotype. To our knowledge, this is the first genetic locus associated with both cancer risk and WHR...
  34. ncbi request reprint Folate receptor alpha regulates cell proliferation in mouse gonadotroph alphaT3-1 cells
    Congjun Yao
    Department of Neurosurgery and Laboratory of Molecular Neurosurgery and Biotechnology, Emory University, School of Medicine, Atlanta, Georgia 30322, USA
    Exp Cell Res 315:3125-32. 2009
    ..Potentially, this finding could be exploited to develop new, innovative molecular targeted treatment for human NF pituitary adenomas...
  35. ncbi request reprint Point mutations alter the cellular distribution of the human folate receptor in cultured Chinese hamster ovary cells
    Michele M Doucette
    Division of Cancer Biology, Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA 30335, USA
    J Nutr 134:308-16. 2004
    ..Furthermore, the fact that mutated FR can be trafficked to the cell surface more efficiently suggests that the native receptor may be retained intracellularly to perform some function there...
  36. ncbi request reprint Genetic variability in iron-related oxidative stress pathways (Nrf2, NQ01, NOS3, and HO-1), iron intake, and risk of postmenopausal breast cancer
    Chi Chen Hong
    Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
    Cancer Epidemiol Biomarkers Prev 16:1784-94. 2007
    ....
  37. ncbi request reprint Fumonisins disrupt sphingolipid metabolism, folate transport, and neural tube development in embryo culture and in vivo: a potential risk factor for human neural tube defects among populations consuming fumonisin-contaminated maize
    Walter F O Marasas
    Medical Research Council, PROMEC Unit, Tygerberg 7505, South Africa
    J Nutr 134:711-6. 2004
    ..Hence, we propose that fumonisins are potential risk factors for NTD, craniofacial anomalies, and other birth defects arising from neural crest cells because of their apparent interference with folate utilization...
  38. ncbi request reprint Prevention of fumonisin B1-induced neural tube defects by folic acid
    T W Sadler
    Department of Cell and Developmental Biology, School of Medicine, University of North Carolina, Chapel Hill, North Carolina 27599 7090, USA
    Teratology 66:169-76. 2002
    ..No information is available about folic acid's potential to protect against this toxicity...

Research Grants1

  1. Folate Polymorphisms, Dietary Folate and Prostate Cancer
    Victoria Stevens; Fiscal Year: 2005
    ..The results of this study are expected to indicate the importance of folate for prostate cancer and whether changing folate consumption can modify the risk associated with genetic variants in the pathway for folate metabolism. ..