H S Feigelson

Summary

Affiliation: American Cancer Society
Country: USA

Publications

  1. pmc Vitamin D pathway gene polymorphisms, diet, and risk of postmenopausal breast cancer: a nested case-control study
    Marjorie L McCullough
    Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road NE, Atlanta, GA 30329, USA
    Breast Cancer Res 9:R9. 2007
  2. pmc A prospective study of XRCC1 (X-ray cross-complementing group 1) polymorphisms and breast cancer risk
    Alpa V Patel
    Department of Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road NE, Atlanta, GA 30309, USA
    Breast Cancer Res 7:R1168-73. 2005
  3. pmc A comprehensive analysis of the androgen receptor gene and risk of breast cancer: results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3)
    David G Cox
    Program in Molecular and Genetic Epidemiology, Epidemiology Department, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Breast Cancer Res 8:R54. 2006
  4. ncbi request reprint Haplotype analysis of the HSD17B1 gene and risk of breast cancer: a comprehensive approach to multicenter analyses of prospective cohort studies
    Heather Spencer Feigelson
    Department of Epidemiology and Surveillance Research, American Cancer Society, National Home Office, Atlanta, Georgia 30329, USA
    Cancer Res 66:2468-75. 2006
  5. ncbi request reprint No association between the progesterone receptor gene +331G/A polymorphism and breast cancer
    Heather Spencer Feigelson
    Department of Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road NE, Atlanta GA 30309, USA
    Cancer Epidemiol Biomarkers Prev 13:1084-5. 2004
  6. ncbi request reprint Weight gain, body mass index, hormone replacement therapy, and postmenopausal breast cancer in a large prospective study
    Heather Spencer Feigelson
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta Georgia 30329, USA
    Cancer Epidemiol Biomarkers Prev 13:220-4. 2004
  7. ncbi request reprint Alcohol, folate, methionine, and risk of incident breast cancer in the American Cancer Society Cancer Prevention Study II Nutrition Cohort
    Heather Spencer Feigelson
    Department of Epidemiology and Surveillance Research, American Cancer Society, National Home Office, Atlanta, Georgia 30329 4251, USA
    Cancer Epidemiol Biomarkers Prev 12:161-4. 2003
  8. ncbi request reprint Transforming growth factor beta receptor type I and transforming growth factor beta1 polymorphisms are not associated with postmenopausal breast cancer
    Heather Spencer Feigelson
    Department of Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road Northeast, Atlanta, GA 30329, USA
    Cancer Epidemiol Biomarkers Prev 15:1236-7. 2006
  9. ncbi request reprint Successful genome-wide scan in paired blood and buccal samples
    Heather Spencer Feigelson
    Department of Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road, NE, Atlanta, GA, USA
    Cancer Epidemiol Biomarkers Prev 16:1023-5. 2007
  10. ncbi request reprint Determinants of DNA yield and quality from buccal cell samples collected with mouthwash
    H S Feigelson
    Department of Epidemiology and Surveillance Research, American Cancer Society, National Home Office, Atlanta, Georgia 30329 4251, USA
    Cancer Epidemiol Biomarkers Prev 10:1005-8. 2001

Collaborators

Detail Information

Publications32

  1. pmc Vitamin D pathway gene polymorphisms, diet, and risk of postmenopausal breast cancer: a nested case-control study
    Marjorie L McCullough
    Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road NE, Atlanta, GA 30329, USA
    Breast Cancer Res 9:R9. 2007
    ..Whether risk is influenced by polymorphisms in other vitamin D metabolism genes and whether calcium or vitamin D intake modifies risk by genotype have not been evaluated...
  2. pmc A prospective study of XRCC1 (X-ray cross-complementing group 1) polymorphisms and breast cancer risk
    Alpa V Patel
    Department of Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road NE, Atlanta, GA 30309, USA
    Breast Cancer Res 7:R1168-73. 2005
    ..We examined the association between polymorphisms in XRCC1 and breast cancer in the American Cancer Society Cancer Prevention Study II (CPS-II) Nutrition Cohort, a large prospective study of cancer incidence in the USA...
  3. pmc A comprehensive analysis of the androgen receptor gene and risk of breast cancer: results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3)
    David G Cox
    Program in Molecular and Genetic Epidemiology, Epidemiology Department, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Breast Cancer Res 8:R54. 2006
    ..Here, we report on the results of a large and comprehensive study of the association between genetic variation in the AR gene and risk of breast cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3)...
  4. ncbi request reprint Haplotype analysis of the HSD17B1 gene and risk of breast cancer: a comprehensive approach to multicenter analyses of prospective cohort studies
    Heather Spencer Feigelson
    Department of Epidemiology and Surveillance Research, American Cancer Society, National Home Office, Atlanta, Georgia 30329, USA
    Cancer Res 66:2468-75. 2006
    ..Although the probability that these ER-negative findings are false-positive results is high, these findings were consistent across each cohort examined and warrant further study...
  5. ncbi request reprint No association between the progesterone receptor gene +331G/A polymorphism and breast cancer
    Heather Spencer Feigelson
    Department of Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road NE, Atlanta GA 30309, USA
    Cancer Epidemiol Biomarkers Prev 13:1084-5. 2004
  6. ncbi request reprint Weight gain, body mass index, hormone replacement therapy, and postmenopausal breast cancer in a large prospective study
    Heather Spencer Feigelson
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta Georgia 30329, USA
    Cancer Epidemiol Biomarkers Prev 13:220-4. 2004
    ..These data illustrate the importance of examining breast cancer risk factors separately by HRT use; the effects of other risk factors may be attenuated or obscured among women taking HRT...
  7. ncbi request reprint Alcohol, folate, methionine, and risk of incident breast cancer in the American Cancer Society Cancer Prevention Study II Nutrition Cohort
    Heather Spencer Feigelson
    Department of Epidemiology and Surveillance Research, American Cancer Society, National Home Office, Atlanta, Georgia 30329 4251, USA
    Cancer Epidemiol Biomarkers Prev 12:161-4. 2003
    ..27). Our results are consistent with a positive association with alcohol but do not support an association with folate or methionine intake or an interaction between folate and alcohol intake on risk of breast cancer...
  8. ncbi request reprint Transforming growth factor beta receptor type I and transforming growth factor beta1 polymorphisms are not associated with postmenopausal breast cancer
    Heather Spencer Feigelson
    Department of Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road Northeast, Atlanta, GA 30329, USA
    Cancer Epidemiol Biomarkers Prev 15:1236-7. 2006
  9. ncbi request reprint Successful genome-wide scan in paired blood and buccal samples
    Heather Spencer Feigelson
    Department of Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road, NE, Atlanta, GA, USA
    Cancer Epidemiol Biomarkers Prev 16:1023-5. 2007
    ..96%). These results show that buccal cell samples collected and processed under optimal conditions can be used for genome-wide association studies with results comparable to those obtained from DNA extracted from buffy coat...
  10. ncbi request reprint Determinants of DNA yield and quality from buccal cell samples collected with mouthwash
    H S Feigelson
    Department of Epidemiology and Surveillance Research, American Cancer Society, National Home Office, Atlanta, Georgia 30329 4251, USA
    Cancer Epidemiol Biomarkers Prev 10:1005-8. 2001
    ..These results suggest that buccal cells should be collected before brushing teeth and processed within 5 days of collection to maximize hDNA yield...
  11. pmc Genetic variation in candidate obesity genes ADRB2, ADRB3, GHRL, HSD11B1, IRS1, IRS2, and SHC1 and risk for breast cancer in the Cancer Prevention Study II
    Heather Spencer Feigelson
    Department of Epidemiology and Surveillance Research, American Cancer Society, Williams Street, NW, Atlanta, Georgia 30303 1002, USA
    Breast Cancer Res 10:R57. 2008
    ..Obesity has consistently been associated with postmenopausal breast cancer risk. Proteins that are secreted by adipose tissue or are involved in regulating body mass may play a role in breast tumor development...
  12. ncbi request reprint Adult weight gain and histopathologic characteristics of breast cancer among postmenopausal women
    Heather Spencer Feigelson
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, Georgia 30329, USA
    Cancer 107:12-21. 2006
    ..Although the link between postmenopausal breast cancer and adiposity is well established, the association between weight gain and specific histopathologic characteristics of breast carcinoma has not been studied carefully...
  13. ncbi request reprint Building a multigenic model of breast cancer susceptibility: CYP17 and HSD17B1 are two important candidates
    H S Feigelson
    American Cancer Society, National Home Office, Atlanta, Georgia 30329 4251, USA
    Cancer Res 61:785-9. 2001
    ..05; 95% CI, 1.29-7.25). These findings suggest that breast cancer risk has a strong genetic component and supports the theory that the underlying mechanism of "complex traits" can be understood using a multigenic model of candidate genes...
  14. pmc Future possibilities in the prevention of breast cancer: role of genetic variation in breast cancer prevention
    H S Feigelson
    American Cancer Society, National Home Office, Atlanta, Georgia 30329 4251, USA
    Breast Cancer Res 2:277-82. 2000
    ..One such tool is the development of a multigenic model of breast cancer susceptibility that can be used to screen women in order to identify those who carry a combination of alleles that puts them at significantly increased risk...
  15. ncbi request reprint Alcohol consumption increases the risk of fatal breast cancer (United States)
    H S Feigelson
    American Cancer Society, National Home Office, Department of Epidemiology and Surveillance Research, Atlanta, GA 30329-4251, USA
    Cancer Causes Control 12:895-902. 2001
    ..CONCLUSION: This study adds to the evidence that postmenopausal women can reduce their risk of breast cancer by avoiding or minimizing their use of alcohol...
  16. ncbi request reprint Dairy, calcium, and vitamin D intake and postmenopausal breast cancer risk in the Cancer Prevention Study II Nutrition Cohort
    Marjorie L McCullough
    Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road Northeast, Atlanta, GA 30329 4251, USA
    Cancer Epidemiol Biomarkers Prev 14:2898-904. 2005
    ..Calcium, vitamin D, and dairy products are highly correlated factors, each with potential roles in breast carcinogenesis. Few prospective studies have examined these relationships in postmenopausal women...
  17. pmc IGF-1, IGFBP-1, and IGFBP-3 polymorphisms predict circulating IGF levels but not breast cancer risk: findings from the Breast and Prostate Cancer Cohort Consortium (BPC3)
    Alpa V Patel
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, Georgia, United States of America
    PLoS ONE 3:e2578. 2008
    ..In summary, the impact of genetic variation in IGF1 and IGFBP3 on circulating IGF levels does not appear to substantially influence breast cancer risk substantially among primarily Caucasian postmenopausal women...
  18. doi request reprint Multiple loci identified in a genome-wide association study of prostate cancer
    Gilles Thomas
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Nat Genet 40:310-5. 2008
    ..Our findings point to multiple loci with moderate effects associated with susceptibility to prostate cancer that, taken together, in the future may predict high risk in select individuals...
  19. doi request reprint Body mass and endometrial cancer risk by hormone replacement therapy and cancer subtype
    Marjorie L McCullough
    Epidemiology and Surveillance Research, American Cancer Society, 250 Williams Street, Atlanta, GA 30303 1002, USA
    Cancer Epidemiol Biomarkers Prev 17:73-9. 2008
    ..87; 95% CI, 1.59-5.16). The increased risk of endometrial cancer across the range of BMI in women who never used postmenopausal HT stresses the need to prevent both overweight and obesity in women...
  20. pmc Haplotypes of the estrogen receptor beta gene and breast cancer risk
    David G Cox
    Program in Molecular and Genetic Epidemiology, Epidemiology Department, Harvard School of Public Health, Boston, MA, USA
    Int J Cancer 122:387-92. 2008
    ..These data suggest that inherited variants in ESR2 (while possibly conferring a small increased risk of breast cancer) are not associated with appreciable (OR > 1.2) changes in breast cancer risk among Caucasian women...
  21. ncbi request reprint Cryopreservation of whole blood samples collected in the field for a large epidemiologic study
    Victoria L Stevens
    Department of Epidemiology and Surveillance Research, American Cancer Society, 250 Williams Street, NW, Atlanta, GA 30303, USA
    Cancer Epidemiol Biomarkers Prev 16:2160-3. 2007
    ....
  22. pmc A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer
    David J Hunter
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Nat Genet 39:870-4. 2007
    ..Our summary results from the GWAS are available online in a form that should speed the identification of additional risk loci...
  23. ncbi request reprint A common 8q24 variant in prostate and breast cancer from a large nested case-control study
    Fredrick R Schumacher
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Cancer Res 67:2951-6. 2007
    ..590). Although the gene responsible has yet to be identified, the validation of this marker in this large sample of prostate cancer cases leaves little room for the possibility of a false-positive result...
  24. ncbi request reprint Genome-wide association study of prostate cancer identifies a second risk locus at 8q24
    Meredith Yeager
    SAIC Frederick, National Cancer Institute NCI Frederick Cancer Research and Development Center, Frederick, Maryland 21702, USA
    Nat Genet 39:645-9. 2007
    ..We estimate that the population attributable risk of the new locus, marked by rs6983267, is higher than the locus marked by rs1447295 (21% versus 9%)...
  25. ncbi request reprint Genetic variation at the CYP19A1 locus predicts circulating estrogen levels but not breast cancer risk in postmenopausal women
    Christopher A Haiman
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90033, USA
    Cancer Res 67:1893-7. 2007
    ..Thus, although genetic variation in CYP19A1 produces measurable differences in estrogen levels among postmenopausal women, the magnitude of the change was insufficient to contribute detectably to breast cancer...
  26. ncbi request reprint Jewish ethnicity and prostate cancer mortality in two large US cohorts
    Carmen Rodriguez
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30329 4251, USA
    Cancer Causes Control 13:271-7. 2002
    ..To investigate prospectively the relationship between Jewish ethnicity and prostate cancer mortality...
  27. ncbi request reprint Concerning the CYP17 MspA1 polymorphism and breast cancer risk: a meta-analysis
    Heather Spencer Feigelson
    Mutagenesis 17:445-6; author reply 447-8. 2002
  28. ncbi request reprint Breast cancer in a multiethnic cohort in Hawaii and Los Angeles: risk factor-adjusted incidence in Japanese equals and in Hawaiians exceeds that in whites
    Malcolm C Pike
    Department of Preventive Medicine, University of Southern California Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Cancer Epidemiol Biomarkers Prev 11:795-800. 2002
    ..The adjusted RR of NHs is 65% greater than that of Ws, and that of migrant Latinas is 16% lower than that of Ws. Elucidating the causes of the high rates in NHs is now a major focus of our efforts...
  29. pmc Polymorphisms in the vascular endothelial growth factor gene and breast cancer in the Cancer Prevention Study II cohort
    Eric J Jacobs
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, Georgia, USA
    Breast Cancer Res 8:R22. 2006
    ..At least four polymorphisms in the VEGF gene have been associated with changes in VEGF expression levels: -2578C/A, -1154G/A and -634G/C are all located in the promoter region; and +936C/T is located in the 3'-untranslated region...
  30. ncbi request reprint Risk factors for fatal breast cancer in African-American women and White women in a large US prospective cohort
    Marjorie L McCullough
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30329 4251, USA
    Am J Epidemiol 162:734-42. 2005
    ..With few exceptions, established breast cancer risk factors were similarly associated with risk of death from breast cancer among African-American women and White women...
  31. doi request reprint The role of body weight in the relationship between physical activity and endometrial cancer: results from a large cohort of US women
    Alpa V Patel
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA, USA
    Int J Cancer 123:1877-82. 2008
    ..51). In summary, light and moderate physical activity including daily life activities were associated with lower endometrial cancer risk in our study, especially among women who are overweight or obese...
  32. ncbi request reprint CYP17 genotype predicts serum hormone levels among pre-menopausal women
    Chanley M Small
    Department of Epidemiology, Emory University, Atlanta, Georgia and American Cancer Society, Atlanta, Georgia 30322, USA
    Hum Reprod 20:2162-7. 2005
    ..There is evidence that a common polymorphism in CYP17 (T27C) is associated with estrogen levels, making it a potential marker of disease risk...