Gerard A Rodrigues

Summary

Affiliation: Allergan Inc
Country: USA

Publications

  1. doi request reprint Differential effects of PPARgamma ligands on oxidative stress-induced death of retinal pigmented epithelial cells
    Gerard A Rodrigues
    Biological Sciences, Allergan, Inc, Irvine, California 92612, USA
    Invest Ophthalmol Vis Sci 52:890-903. 2011
  2. doi request reprint Roles of αvβ5, FAK and MerTK in oxidative stress inhibition of RPE cell phagocytosis
    Suofu Qin
    Retinal Disease Research, Department of Biological Sciences, Allergan, Inc, RD3 2D, 2525 Dupont Drive, Irvine, CA 92612 1599, USA
    Exp Eye Res 94:63-70. 2012
  3. doi request reprint Inhibition of RPE cell sterile inflammatory responses and endotoxin-induced uveitis by a cell-impermeable HSP90 inhibitor
    Suofu Qin
    Retinal Disease Research, Department of Biological Sciences, Allergan, Inc, 2525 Dupont Drive, Irvine, CA 92612, USA
    Exp Eye Res 93:889-97. 2011
  4. doi request reprint Differential roles of AMPKα1 and AMPKα2 in regulating 4-HNE-induced RPE cell death and permeability
    Suofu Qin
    Retinal Disease Research, Department of Biological Sciences, Allergan, Inc, 2525 Dupont Drive, Irvine, CA 92612, USA
    Exp Eye Res 91:818-24. 2010
  5. ncbi request reprint Resveratrol protects RPE cells from sodium iodate by modulating PPARα and PPARδ
    Suofu Qin
    Retinal Disease Research, Department of Biological Sciences, Allergan, Inc, 2525 Dupont Drive, Irvine, CA 92612, USA Electronic address
    Exp Eye Res 118:100-8. 2014
  6. pmc Progress and perspectives on the role of RPE cell inflammatory responses in the development of age-related macular degeneration
    Suofu Qin
    Retinal Disease Research, Department of Biological Sciences, Allergan, Inc, Irvine, CA, USA
    J Inflamm Res 1:49-65. 2008

Collaborators

Detail Information

Publications6

  1. doi request reprint Differential effects of PPARgamma ligands on oxidative stress-induced death of retinal pigmented epithelial cells
    Gerard A Rodrigues
    Biological Sciences, Allergan, Inc, Irvine, California 92612, USA
    Invest Ophthalmol Vis Sci 52:890-903. 2011
    ..To investigate the role of the peroxisome proliferator-activated receptor (PPAR)-γ in modulating retinal pigmented epithelium (RPE) responses to oxidative stress...
  2. doi request reprint Roles of αvβ5, FAK and MerTK in oxidative stress inhibition of RPE cell phagocytosis
    Suofu Qin
    Retinal Disease Research, Department of Biological Sciences, Allergan, Inc, RD3 2D, 2525 Dupont Drive, Irvine, CA 92612 1599, USA
    Exp Eye Res 94:63-70. 2012
    ..Our data demonstrate that sub-lethal oxidative treatment with H(2)O(2) inhibits phagocytic activity of ARPE-19 cells, in part by inhibiting FAK and MerTK...
  3. doi request reprint Inhibition of RPE cell sterile inflammatory responses and endotoxin-induced uveitis by a cell-impermeable HSP90 inhibitor
    Suofu Qin
    Retinal Disease Research, Department of Biological Sciences, Allergan, Inc, 2525 Dupont Drive, Irvine, CA 92612, USA
    Exp Eye Res 93:889-97. 2011
    ..Collectively, our data identify HSP90 as a pro-inflammatory molecule in RPE cell sterile inflammatory responses...
  4. doi request reprint Differential roles of AMPKα1 and AMPKα2 in regulating 4-HNE-induced RPE cell death and permeability
    Suofu Qin
    Retinal Disease Research, Department of Biological Sciences, Allergan, Inc, 2525 Dupont Drive, Irvine, CA 92612, USA
    Exp Eye Res 91:818-24. 2010
    ..Therefore, selective modulation of AMPKα activity may benefit patients with retinal degeneration associated with RPE cell atrophy...
  5. ncbi request reprint Resveratrol protects RPE cells from sodium iodate by modulating PPARα and PPARδ
    Suofu Qin
    Retinal Disease Research, Department of Biological Sciences, Allergan, Inc, 2525 Dupont Drive, Irvine, CA 92612, USA Electronic address
    Exp Eye Res 118:100-8. 2014
    ..PPARα and δ modulators might ameliorate stress-induced RPE degeneration in vivo. ..
  6. pmc Progress and perspectives on the role of RPE cell inflammatory responses in the development of age-related macular degeneration
    Suofu Qin
    Retinal Disease Research, Department of Biological Sciences, Allergan, Inc, Irvine, CA, USA
    J Inflamm Res 1:49-65. 2008
    ..In addition, potential target areas for therapeutic intervention will be discussed and new experimental therapeutic strategies for atrophic AMD will be presented...