Robert Olney

Summary

Affiliation: Alfred I. duPont Hospital for Children
Country: USA

Publications

  1. doi request reprint C-Type Natriuretic Peptide (CNP) levels are altered in boys with Klinefelter syndrome
    Robert C Olney
    Nemours Children s Clinic, Jacksonville, Florida 32207, USA
    J Clin Endocrinol Metab 97:4206-11. 2012
  2. pmc Amino-terminal propeptide of C-type natriuretic peptide (NTproCNP) predicts height velocity in healthy children
    Robert C Olney
    Division of Endocrinology, Nemours Children s Clinic, Jacksonville, FL 32207, USA
    Clin Endocrinol (Oxf) 77:416-22. 2012
  3. doi request reprint Mechanisms of impaired growth: effect of steroids on bone and cartilage
    Robert C Olney
    Division of Pediatric Endocrinology, Nemours Children s Clinic, Jacksonville, FL 32207, USA
    Horm Res 72:30-5. 2009
  4. doi request reprint Healthy children with frequent fractures: how much evaluation is needed?
    Robert C Olney
    Division of Pediatric Endocrinology, Nemours Children s Clinic Jacksonville, Jacksonville, FL 32207, USA
    Pediatrics 121:890-7. 2008
  5. ncbi request reprint Amino-terminal propeptide of C-type natriuretic peptide and linear growth in children: effects of puberty, testosterone, and growth hormone
    Robert C Olney
    Division of Pediatric Endocrinology, Nemours Children s Clinic Jacksonville, Jacksonville, Florida 32207, USA
    J Clin Endocrinol Metab 92:4294-8. 2007
  6. ncbi request reprint C-type natriuretic peptide in growth: a new paradigm
    Robert C Olney
    Division of Pediatric Endocrinology, Nemours Children s Clinic, 807 Children s Way, Jacksonville, FL 32207, USA
    Growth Horm IGF Res 16:S6-14. 2006
  7. ncbi request reprint Heterozygous mutations in natriuretic peptide receptor-B (NPR2) are associated with short stature
    Robert C Olney
    Division of Endocrinology, Nemours Children s Clinic, Jacksonville, FL 32207, USA
    J Clin Endocrinol Metab 91:1229-32. 2006
  8. ncbi request reprint Growth factor regulation of human growth plate chondrocyte proliferation in vitro
    Robert C Olney
    Cellular and Molecular Medicine Laboratory, The Nemours Children s Clinic, 807 Children s Way, Jacksonville, FL 32207, USA
    Biochem Biophys Res Commun 317:1171-82. 2004
  9. ncbi request reprint Regulation of bone mass by growth hormone
    Robert C Olney
    The Nemours Children s Clinic, Jacksonville, Florida 32207, USA
    Med Pediatr Oncol 41:228-34. 2003
  10. ncbi request reprint Using real-time, quantitative PCR for rapid genotyping of the steroid 21-hydroxylase gene in a north Florida population
    Robert C Olney
    The Nemours Children s Clinic, Jacksonville, Florida 32207, USA
    J Clin Endocrinol Metab 87:735-41. 2002

Research Grants

Collaborators

Detail Information

Publications13

  1. doi request reprint C-Type Natriuretic Peptide (CNP) levels are altered in boys with Klinefelter syndrome
    Robert C Olney
    Nemours Children s Clinic, Jacksonville, Florida 32207, USA
    J Clin Endocrinol Metab 97:4206-11. 2012
    ..We explored the possibility that alterations in natriuretic peptide regulation may play a role in the overgrowth of boys with Klinefelter syndrome...
  2. pmc Amino-terminal propeptide of C-type natriuretic peptide (NTproCNP) predicts height velocity in healthy children
    Robert C Olney
    Division of Endocrinology, Nemours Children s Clinic, Jacksonville, FL 32207, USA
    Clin Endocrinol (Oxf) 77:416-22. 2012
    ..The objectives of the study were to correlate NTproCNP levels with height velocity and to define the reference range for plasma CNP and NTproCNP across childhood...
  3. doi request reprint Mechanisms of impaired growth: effect of steroids on bone and cartilage
    Robert C Olney
    Division of Pediatric Endocrinology, Nemours Children s Clinic, Jacksonville, FL 32207, USA
    Horm Res 72:30-5. 2009
    ..These reductions in chondrocyte function result in decreased linear growth...
  4. doi request reprint Healthy children with frequent fractures: how much evaluation is needed?
    Robert C Olney
    Division of Pediatric Endocrinology, Nemours Children s Clinic Jacksonville, Jacksonville, FL 32207, USA
    Pediatrics 121:890-7. 2008
    ..We performed a case-control study to determine whether occult bone disease is associated with a history of frequent fractures in children...
  5. ncbi request reprint Amino-terminal propeptide of C-type natriuretic peptide and linear growth in children: effects of puberty, testosterone, and growth hormone
    Robert C Olney
    Division of Pediatric Endocrinology, Nemours Children s Clinic Jacksonville, Jacksonville, Florida 32207, USA
    J Clin Endocrinol Metab 92:4294-8. 2007
    ..The amino-terminal propeptide of CNP (NTproCNP) is produced in equimolar amounts with CNP and is measurable in plasma, providing a potential biomarker for growth plate activity and, hence, linear growth...
  6. ncbi request reprint C-type natriuretic peptide in growth: a new paradigm
    Robert C Olney
    Division of Pediatric Endocrinology, Nemours Children s Clinic, 807 Children s Way, Jacksonville, FL 32207, USA
    Growth Horm IGF Res 16:S6-14. 2006
    ..Considerable work is needed to further understand this new paradigm of human growth regulation...
  7. ncbi request reprint Heterozygous mutations in natriuretic peptide receptor-B (NPR2) are associated with short stature
    Robert C Olney
    Division of Endocrinology, Nemours Children s Clinic, Jacksonville, FL 32207, USA
    J Clin Endocrinol Metab 91:1229-32. 2006
    ..The phenotype of heterozygous carriers of NPR2 mutations is less clear...
  8. ncbi request reprint Growth factor regulation of human growth plate chondrocyte proliferation in vitro
    Robert C Olney
    Cellular and Molecular Medicine Laboratory, The Nemours Children s Clinic, 807 Children s Way, Jacksonville, FL 32207, USA
    Biochem Biophys Res Commun 317:1171-82. 2004
    ....
  9. ncbi request reprint Regulation of bone mass by growth hormone
    Robert C Olney
    The Nemours Children s Clinic, Jacksonville, Florida 32207, USA
    Med Pediatr Oncol 41:228-34. 2003
    ..GH deficiency severely limits bone growth and hence the accumulation of bone mass. GH deficiency is not an uncommon complication in oncology and has long-term effects on bone health...
  10. ncbi request reprint Using real-time, quantitative PCR for rapid genotyping of the steroid 21-hydroxylase gene in a north Florida population
    Robert C Olney
    The Nemours Children s Clinic, Jacksonville, Florida 32207, USA
    J Clin Endocrinol Metab 87:735-41. 2002
    ..Faster results will allow for more timely initiation of appropriate therapy and limit the exposure of potentially unnecessary therapy...
  11. ncbi request reprint Expression of the components of the insulin-like growth factor axis across the growth-plate
    R C Olney
    Division of Endocrinology, The Nemours Children s Clinic, Jacksonville, FL 32207, USA
    Mol Cell Endocrinol 156:63-71. 1999
    ..Since IGF-I and -II are potent stimulators of proliferation, the down-regulation of these genes may be necessary in order for hypertrophy to proceed...
  12. ncbi request reprint Oxandrolone enhances skeletal muscle myosin synthesis and alters global gene expression profile in Duchenne muscular dystrophy
    Prabhakaran Balagopal
    Nemours Children s Clinic, Jacksonville, FL 32207, USA
    Am J Physiol Endocrinol Metab 290:E530-9. 2006
    ....
  13. pmc A novel STX16 deletion in autosomal dominant pseudohypoparathyroidism type Ib redefines the boundaries of a cis-acting imprinting control element of GNAS
    Agnes Linglart
    Endocrine Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Hum Genet 76:804-14. 2005
    ..4-kb deletion of STX16 and who had normal serum parathyroid hormone levels until the age of 21 mo...

Research Grants4

  1. REGULATORY MECHANISMS OF GROWTH-PLATE CHONDROCYTES
    Robert Olney; Fiscal Year: 2002
    ..Conversely, by identifying the important regulators of the human growth-plate, we will provide clues to direct the search for the genes responsible for some of the osteochondrodysplasias. ..