Naj A Sharif

Summary

Affiliation: Alcon Research
Country: USA

Publications

  1. Sharif N, Crider J, Xu S, Williams G. Affinities, selectivities, potencies, and intrinsic activities of natural and synthetic prostanoids using endogenous receptors: focus on DP class prostanoids. J Pharmacol Exp Ther. 2000;293:321-8 pubmed
    ..9-8.2, n = 5-9). The pharmacological properties of some natural and numerous DP class synthetic prostanoids have been determined using endogenous receptors. ..
  2. Sharif N, Xu S. Binding affinities of ocular hypotensive beta-blockers levobetaxolol, levobunolol, and timolol at endogenous guinea pig beta-adrenoceptors. J Ocul Pharmacol Ther. 2004;20:93-9 pubmed
    ..These data indicated that while levobetaxolol and betaxolol possessed a 193-233-fold selectivity for beta(1)-receptors, levobunolol exhibited a 140-fold beta(2)-receptor selectivity and (l)-timolol was essentially nonselective...
  3. Sharif N, McLaughlin M, Kelly C, Xu S, Crider J, Williams G, et al. Preclinical pharmacology of AL-12182, a new ocular hypotensive 11-oxa prostaglandin analog. J Ocul Pharmacol Ther. 2006;22:291-309 pubmed
    ....
  4. Sharif N, McLaughlin M, Kelly C, Katoli P, Drace C, Husain S, et al. Cabergoline: Pharmacology, ocular hypotensive studies in multiple species, and aqueous humor dynamic modulation in the Cynomolgus monkey eyes. Exp Eye Res. 2009;88:386-97 pubmed publisher
    ....

Locale

Detail Information

Publications4

  1. Sharif N, Crider J, Xu S, Williams G. Affinities, selectivities, potencies, and intrinsic activities of natural and synthetic prostanoids using endogenous receptors: focus on DP class prostanoids. J Pharmacol Exp Ther. 2000;293:321-8 pubmed
    ..9-8.2, n = 5-9). The pharmacological properties of some natural and numerous DP class synthetic prostanoids have been determined using endogenous receptors. ..
  2. Sharif N, Xu S. Binding affinities of ocular hypotensive beta-blockers levobetaxolol, levobunolol, and timolol at endogenous guinea pig beta-adrenoceptors. J Ocul Pharmacol Ther. 2004;20:93-9 pubmed
    ..These data indicated that while levobetaxolol and betaxolol possessed a 193-233-fold selectivity for beta(1)-receptors, levobunolol exhibited a 140-fold beta(2)-receptor selectivity and (l)-timolol was essentially nonselective...
  3. Sharif N, McLaughlin M, Kelly C, Xu S, Crider J, Williams G, et al. Preclinical pharmacology of AL-12182, a new ocular hypotensive 11-oxa prostaglandin analog. J Ocul Pharmacol Ther. 2006;22:291-309 pubmed
    ....
  4. Sharif N, McLaughlin M, Kelly C, Katoli P, Drace C, Husain S, et al. Cabergoline: Pharmacology, ocular hypotensive studies in multiple species, and aqueous humor dynamic modulation in the Cynomolgus monkey eyes. Exp Eye Res. 2009;88:386-97 pubmed publisher
    ....