Jonathan Warner

Summary

Affiliation: Albert Einstein College of Medicine
Country: USA

Publications

  1. ncbi request reprint Yeast ribosomes: variety is the spice of life
    Kerri B McIntosh
    Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Cell 131:450-1. 2007
  2. pmc How common are extraribosomal functions of ribosomal proteins?
    Jonathan R Warner
    Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Mol Cell 34:3-11. 2009
  3. ncbi request reprint The economics of ribosome biosynthesis in yeast
    J R Warner
    Dept of Cell Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, New York, Bronx, NY 10461, USA
    Trends Biochem Sci 24:437-40. 1999
  4. ncbi request reprint Nascent ribosomes
    J R Warner
    Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Cell 107:133-6. 2001
  5. ncbi request reprint The discovery of polyribosomes
    Jonathan R Warner
    Dept of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Trends Biochem Sci 27:376-80. 2002
  6. pmc Autoregulation in the biosynthesis of ribosomes
    Yu Zhao
    Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Mol Cell Biol 23:699-707. 2003
  7. doi request reprint The fast track is cotranscriptional
    Jonathan R Warner
    Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Mol Cell 37:745-6. 2010
  8. pmc Constructing ribosomes along the Danube
    Jonathan R Warner
    Department of Cell Biology, Albert Einstein College of Medicine, NY, USA
    EMBO Rep 11:6-8. 2010
  9. pmc Potential interface between ribosomal protein production and pre-rRNA processing
    Dipayan Rudra
    Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Mol Cell Biol 27:4815-24. 2007
  10. pmc Fine-structure analysis of ribosomal protein gene transcription
    Yu Zhao
    Department of Cell Biology, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY 10461, USA
    Mol Cell Biol 26:4853-62. 2006

Research Grants

  1. RIBOSOMAL GENES OF YEAST AND THEIR REGULATION
    Jonathan Warner; Fiscal Year: 2002
  2. RIBOSOMAL GENES OF YEAST AND THEIR REGULATION
    Jonathan Warner; Fiscal Year: 2006
  3. RIBOSOMAL GENES OF YEAST AND THEIR REGULATION
    Jonathan Warner; Fiscal Year: 2007
  4. RIBOSOMAL GENES OF YEAST AND THEIR REGULATION
    Jonathan Warner; Fiscal Year: 2007
  5. RIBOSOMAL GENES OF YEAST AND THEIR REGULATION
    Jonathan Warner; Fiscal Year: 2009
  6. RIBOSOMAL GENES OF YEAST AND THEIR REGULATION
    Jonathan R Warner; Fiscal Year: 2010
  7. RIBOSOMAL GENES OF YEAST AND THEIR REGULATION
    Jonathan Warner; Fiscal Year: 1990
  8. RIBOSOMAL GENES OF YEAST AND THEIR REGULATION
    Jonathan Warner; Fiscal Year: 1993
  9. RIBOSOMAL PROTEIN GENES OF SACCHAROMYCES SEREVISIAE
    Jonathan Warner; Fiscal Year: 1980
  10. RIBOSOMAL GENES OF YEAST AND THEIR REGULATION
    Jonathan Warner; Fiscal Year: 2009

Collaborators

  • D Shore
  • Ian Willis
  • Dipayan Rudra
  • Yu Zhao
  • Arpita Bhattacharya
  • Kerri B McIntosh
  • Jaideep Mallick
  • Stephan Schawalder
  • Jung Hoon Sohn

Detail Information

Publications14

  1. ncbi request reprint Yeast ribosomes: variety is the spice of life
    Kerri B McIntosh
    Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Cell 131:450-1. 2007
    ..Komili et al. (2007) now report that these paralogous genes are not functionally equivalent, suggesting the possible existence of a "ribosome code."..
  2. pmc How common are extraribosomal functions of ribosomal proteins?
    Jonathan R Warner
    Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Mol Cell 34:3-11. 2009
    ..Is this due to a lack of imaginative evolution by cells and viruses, or to a lack of imaginative experiments by molecular biologists?..
  3. ncbi request reprint The economics of ribosome biosynthesis in yeast
    J R Warner
    Dept of Cell Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, New York, Bronx, NY 10461, USA
    Trends Biochem Sci 24:437-40. 1999
    ..This is entrusted to a number of signal transduction pathways that can abruptly induce or silence the ribosomal genes, leading to major implications for the expression of other genes as well...
  4. ncbi request reprint Nascent ribosomes
    J R Warner
    Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Cell 107:133-6. 2001
    ..Two papers published recently in Molecular Cell provide first looks at the association of these processing factors with the intermediates in ribosome synthesis (Harnpicharnchai et al., 2001; Bassler et al., 2001)...
  5. ncbi request reprint The discovery of polyribosomes
    Jonathan R Warner
    Dept of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Trends Biochem Sci 27:376-80. 2002
  6. pmc Autoregulation in the biosynthesis of ribosomes
    Yu Zhao
    Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Mol Cell Biol 23:699-707. 2003
    ....
  7. doi request reprint The fast track is cotranscriptional
    Jonathan R Warner
    Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Mol Cell 37:745-6. 2010
    ..In this issue of Molecular Cell, Kos and Tollervey (2010) report their findings from rapid-labeling kinetics and quantitative analyses to address this issue...
  8. pmc Constructing ribosomes along the Danube
    Jonathan R Warner
    Department of Cell Biology, Albert Einstein College of Medicine, NY, USA
    EMBO Rep 11:6-8. 2010
    ..Both of these topics have recently seen important advances that enlighten how almost 200 proteins cooperate to produce a ribosome and how the cell responds to a malfunction in this process...
  9. pmc Potential interface between ribosomal protein production and pre-rRNA processing
    Dipayan Rudra
    Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Mol Cell Biol 27:4815-24. 2007
    ..We propose a model in which the CURI complex is a key mediator between the two parallel pathways necessary for ribosome synthesis: the transcription and processing of pre-rRNA and the transcription of ribosomal protein genes...
  10. pmc Fine-structure analysis of ribosomal protein gene transcription
    Yu Zhao
    Department of Cell Biology, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY 10461, USA
    Mol Cell Biol 26:4853-62. 2006
    ..Fine-structure chromatin mapping of several ribosomal protein promoters revealed that histones are essentially absent from the Rap1 sites, while Fhl1 and Ifh1 are coincident with each other but distinct from Rap1...
  11. pmc Central role of Ifh1p-Fhl1p interaction in the synthesis of yeast ribosomal proteins
    Dipayan Rudra
    Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    EMBO J 24:533-42. 2005
    ..Homeostatic mechanisms within the cell respond by reducing the transcription of rRNA to match the output of RPs, and by reducing the global transcription of mRNA to match the capacity of the translational apparatus...
  12. doi request reprint Tbf1 or not Tbf1?
    Arpita Bhattacharya
    Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Mol Cell 29:537-8. 2008
    ..cerevisiae and, en passant, raise interesting questions about the relationship between RP genes and telomeres...
  13. ncbi request reprint What better measure than ribosome synthesis?
    Dipayan Rudra
    Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Genes Dev 18:2431-6. 2004
  14. pmc Why Dom34 stimulates growth of cells with defects of 40S ribosomal subunit biosynthesis
    Arpita Bhattacharya
    Department of Cell Biology, Albert Einstein College of Medicine, 1300 Morris Avenue, Bronx, NY 10461, USA
    Mol Cell Biol 30:5562-71. 2010
    ....

Research Grants35

  1. RIBOSOMAL GENES OF YEAST AND THEIR REGULATION
    Jonathan Warner; Fiscal Year: 2002
    ..Our hope, and expectation, is that understanding the circuits that underlie the regulation of ribosome synthesis will lead to more effective intervention when an imbalance occurs. ..
  2. RIBOSOMAL GENES OF YEAST AND THEIR REGULATION
    Jonathan Warner; Fiscal Year: 2006
    ..We will examine the several parts of both the protein degradation pathway and the RNA degradation pathway to determine which is involved in this important task. We propose a mutant screen to identify key players. ..
  3. RIBOSOMAL GENES OF YEAST AND THEIR REGULATION
    Jonathan Warner; Fiscal Year: 2007
    ....
  4. RIBOSOMAL GENES OF YEAST AND THEIR REGULATION
    Jonathan Warner; Fiscal Year: 2007
    ..abstract_text> ..
  5. RIBOSOMAL GENES OF YEAST AND THEIR REGULATION
    Jonathan Warner; Fiscal Year: 2009
    ....
  6. RIBOSOMAL GENES OF YEAST AND THEIR REGULATION
    Jonathan R Warner; Fiscal Year: 2010
    ....
  7. RIBOSOMAL GENES OF YEAST AND THEIR REGULATION
    Jonathan Warner; Fiscal Year: 1990
    ..Finally, we will analyze the mechanism for translational control of ribosomal protein synthesis, with emphasis on testing the hypothesis that a regulatory molecule interacts with the m7G cap and its adjacent sequences...
  8. RIBOSOMAL GENES OF YEAST AND THEIR REGULATION
    Jonathan Warner; Fiscal Year: 1993
    ..REB1 appears to share an unusual DNA binding domain with the oncogene, myb. By targeted mutation of the yeast protein we expect to learn more about the characteristics of such DNA-protein interactions...
  9. RIBOSOMAL PROTEIN GENES OF SACCHAROMYCES SEREVISIAE
    Jonathan Warner; Fiscal Year: 1980
    ..region and not much else? (d) eventually, by sequencing the regions adjacent to the 5' end of the mRNA for several ribosomal protein genes, can we identify a sequence which is responsible for coordinate transcription of the genes? ..
  10. RIBOSOMAL GENES OF YEAST AND THEIR REGULATION
    Jonathan Warner; Fiscal Year: 2009
    ....