JANA VELISKOVA

Summary

Affiliation: Albert Einstein College of Medicine
Country: USA

Publications

  1. ncbi request reprint The role of estrogens in seizures and epilepsy: the bad guys or the good guys?
    J Veliskova
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Neuroscience 138:837-44. 2006
  2. ncbi request reprint Estrogens and epilepsy: why are we so excited?
    JANA VELISKOVA
    The Saul R Korey Department of Neurology and the Dominick P Purpura Department of Neuroscience, Laboratory of Developmental Epilepsy, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Neuroscientist 13:77-88. 2007
  3. ncbi request reprint Beta-estradiol increases dentate gyrus inhibition in female rats via augmentation of hilar neuropeptide Y
    JANA VELISKOVA
    Saul R Korey Department of Neurology, Laboratory of Developmental Epilepsy, Albert Einstein College of Medicine and the Einstein Montefiore Comprehensive Epilepsy Management Center, Bronx, New York 10461, USA
    J Neurosci 27:6054-63. 2007
  4. ncbi request reprint The involvement of the substantia nigra pars reticulata in hypoglycemic seizures
    JANA VELISKOVA
    Department of Neurology, and Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Epilepsia 48:106-8. 2007
  5. pmc Regional neural activity within the substantia nigra during peri-ictal flurothyl generalized seizure stages
    JANA VELISKOVA
    Department of Neurology, Albert Einstein College of Medicine, AECOM, K314, 1410 Pelham Parkway South, Bronx, NY 10461, USA
    Neurobiol Dis 20:752-9. 2005
  6. ncbi request reprint Sex-specific control of flurothyl-induced tonic-clonic seizures by the substantia nigra pars reticulata during development
    LIBOR VELISEK
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Exp Neurol 201:203-11. 2006
  7. ncbi request reprint Seizures in the developing brain
    JANA VELISKOVA
    Department of Neurology, Montofiore Einstein Epilepsy Management Center, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York 10461, USA
    Epilepsia 45:6-12. 2004
  8. ncbi request reprint Circling behavior and [14C]2-deoxyglucose mapping in rats: possible implications for autistic repetitive behaviors
    LIBOR VELISEK
    Department of Neurology, Albert Einstein College of Medicine, 1410 Pelham Parkway South, Bronx, NY 10461, USA
    Neurobiol Dis 18:346-55. 2005
  9. pmc Metabolic environment in substantia nigra reticulata is critical for the expression and control of hypoglycemia-induced seizures
    LIBOR VELISEK
    The Saul R Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    J Neurosci 28:9349-62. 2008
  10. ncbi request reprint Effects of status epilepticus early in life on susceptibility to ischemic injury in adulthood
    Filippo S Giorgi
    Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA
    Epilepsia 46:490-8. 2005

Collaborators

Detail Information

Publications27

  1. ncbi request reprint The role of estrogens in seizures and epilepsy: the bad guys or the good guys?
    J Veliskova
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Neuroscience 138:837-44. 2006
    ..Several signaling pathways may be involved in the neuroprotective effects of beta-estradiol on status epilepticus-induced hippocampal damage but at least one of these pathways involves interactions with neuropeptide Y...
  2. ncbi request reprint Estrogens and epilepsy: why are we so excited?
    JANA VELISKOVA
    The Saul R Korey Department of Neurology and the Dominick P Purpura Department of Neuroscience, Laboratory of Developmental Epilepsy, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Neuroscientist 13:77-88. 2007
    ....
  3. ncbi request reprint Beta-estradiol increases dentate gyrus inhibition in female rats via augmentation of hilar neuropeptide Y
    JANA VELISKOVA
    Saul R Korey Department of Neurology, Laboratory of Developmental Epilepsy, Albert Einstein College of Medicine and the Einstein Montefiore Comprehensive Epilepsy Management Center, Bronx, New York 10461, USA
    J Neurosci 27:6054-63. 2007
    ....
  4. ncbi request reprint The involvement of the substantia nigra pars reticulata in hypoglycemic seizures
    JANA VELISKOVA
    Department of Neurology, and Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Epilepsia 48:106-8. 2007
    ..These data suggest that during hypoglycemia, the SNR seizure controlling system has different properties than in seizure models not involving a metabolic stress...
  5. pmc Regional neural activity within the substantia nigra during peri-ictal flurothyl generalized seizure stages
    JANA VELISKOVA
    Department of Neurology, Albert Einstein College of Medicine, AECOM, K314, 1410 Pelham Parkway South, Bronx, NY 10461, USA
    Neurobiol Dis 20:752-9. 2005
    ..The postictal suppression state was correlated with changes in the SNR projection targets, specifically the pedunculopontine tegmental nucleus and superior colliculus...
  6. ncbi request reprint Sex-specific control of flurothyl-induced tonic-clonic seizures by the substantia nigra pars reticulata during development
    LIBOR VELISEK
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Exp Neurol 201:203-11. 2006
    ..Although GABAergic inhibition in the SNR affects tonic-clonic seizures in developing rats, only the NMDA antagonist had consistent anticonvulsant effects throughout development...
  7. ncbi request reprint Seizures in the developing brain
    JANA VELISKOVA
    Department of Neurology, Montofiore Einstein Epilepsy Management Center, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York 10461, USA
    Epilepsia 45:6-12. 2004
    ..By contrast, female SNR does not contain any region that mediates muscimol-related proconvulsant effects. As with the adult, immature female rats do not develop a proconvulsant SNR region at any age...
  8. ncbi request reprint Circling behavior and [14C]2-deoxyglucose mapping in rats: possible implications for autistic repetitive behaviors
    LIBOR VELISEK
    Department of Neurology, Albert Einstein College of Medicine, 1410 Pelham Parkway South, Bronx, NY 10461, USA
    Neurobiol Dis 18:346-55. 2005
    ....
  9. pmc Metabolic environment in substantia nigra reticulata is critical for the expression and control of hypoglycemia-induced seizures
    LIBOR VELISEK
    The Saul R Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    J Neurosci 28:9349-62. 2008
    ..The results suggest that fasting and insulin-induced hypoglycemia can lead to impairment in the function of the SNR, leading thus to hypoglycemic seizures...
  10. ncbi request reprint Effects of status epilepticus early in life on susceptibility to ischemic injury in adulthood
    Filippo S Giorgi
    Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA
    Epilepsia 46:490-8. 2005
    ..The purpose of this study was to determine the effect of SE induced in immature (15 days old; PN15) male rats, on susceptibility to subsequent transient focal cerebral ischemia induced in adulthood...
  11. ncbi request reprint Correlation between extracellular glucose and seizure susceptibility in adult rats
    Evan M Schwechter
    Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY, USA
    Ann Neurol 53:91-101. 2003
    ..Data indicate that, in the adult rats, high glucose concentrations are associated with proconvulsant effects...
  12. pmc The role of substantia nigra pars reticulata in modulating clonic seizures is determined by testosterone levels during the immediate postnatal period
    Filippo S Giorgi
    The Saul R Korey Department of Neurology, Laboratory of Developmental Epilepsy, Albert Einstein College of Medicine, 1410 Pelham Parkway South, Bronx, NY 10461, USA
    Neurobiol Dis 25:73-9. 2007
    ..The data suggest that the PN0-2 period is critical for the development of the seizure-controlling SNR system; the hormonal effect on seizure control is independent from their effect on GABA conductance...
  13. pmc Model of cryptogenic infantile spasms after prenatal corticosteroid priming
    LIBOR VELISEK
    The Saul R Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Epilepsia 51:145-9. 2010
    ....
  14. ncbi request reprint Electrical stimulation of substantia nigra pars reticulata is anticonvulsant in adult and young male rats
    LIBOR VELISEK
    Department of Neurology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Exp Neurol 173:145-52. 2002
    ..The data suggest that the SNR may be a candidate site for deep brain stimulation for the treatment of epilepsy...
  15. ncbi request reprint Sex differences in GABA(A)ergic system in rat substantia nigra pars reticulata
    Teresa Ravizza
    Department of Neurology, Albert Einstein College of Medicine, K311, 1410 Pelham Parkway South, Bronx, NY 10461, USA
    Int J Dev Neurosci 21:245-54. 2003
    ....
  16. ncbi request reprint Estradiol reduces seizure-induced hippocampal injury in ovariectomized female but not in male rats
    Aristea S Galanopoulou
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA
    Neurosci Lett 342:201-5. 2003
    ..In males, estradiol increased the total damage score. These findings suggest that the effects of estradiol on seizure threshold and damage may be altered by sex-related differences in the hormonal environment...
  17. ncbi request reprint Estrogen treatment protects GABA(B) inhibition in the dentate gyrus of female rats after kainic acid-induced status epilepticus
    LIBOR VELISEK
    Department of Neurology K312, Albert Einstein College of Medicine, 1410 Pelham Parkway South, Bronx, NY 10461, U S A
    Epilepsia 43:146-51. 2002
    ..Additionally, we determined whether the lost function could be preserved by using estrogen neuroprotection...
  18. ncbi request reprint Age-dependent consequences of status epilepticus: animal models
    Morris H Scantlebury
    Korey Department of Neurology, Albert Einstein College of Medicine, Pelham Parkway South, Kennedy Center, Bronx, NY, USA
    Epilepsia 48:75-82. 2007
    ..Better understanding of the pathophysiologic mechanisms underlying the age-specific alterations to the brain induced by SE will lead to the development of novel and effective strategies to improve the deleterious consequences...
  19. pmc Blockade of androgen receptors is sufficient to alter the sexual differentiation of the substantia nigra pars reticulata seizure-controlling network
    James G Heida
    Saul R Korey Department of Neurology, Laboratory of Developemental Epilepsy, The Montefiore Einstein Epilepsy Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Epileptic Disord 10:8-12. 2008
    ..Thus, activation of androgen receptors is important for the presence of proconvulsant SNR muscimol responses...
  20. pmc Validation of the rat model of cryptogenic infantile spasms
    Tamar Chachua
    Department of Neurology, Albert Einstein College of Medicine Einstein Montefiore Comprehensive Epilepsy Center, Bronx, New York, USA
    Epilepsia 52:1666-77. 2011
    ....
  21. pmc Females, their estrogens, and seizures
    JANA VELISKOVA
    The Saul R Korey Department of Neurology, Albert Einstein College of Medicine, 1410 Pelham Parkway South, Bronx, New York 10461, USA
    Epilepsia 51:141-4. 2010
    ..The effects of estrogens on seizures are contradictory. More studies are necessary to determine under which conditions the estrogens have proconvulsant effects and when the estrogens may have beneficial action in patients with epilepsy...
  22. ncbi request reprint Developmental aspects of the basal ganglia and therapeutic perspectives
    JANA VELISKOVA
    Deptartment of Neurology, Albert Einstein College of Medicine, 1410 Pelham Parkway South, Bronx, NY 10461, USA
    Epileptic Disord 4:S73-82. 2002
    ..Better understanding of the influence of the endocrine system on brain development and neuronal activity may provide new insight into the treatment of age- and sex-dependent seizure disorders...
  23. ncbi request reprint Model of infantile spasms induced by N-methyl-D-aspartic acid in prenatally impaired brain
    LIBOR VELISEK
    Saul R Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Ann Neurol 61:109-19. 2007
    ....
  24. ncbi request reprint Susceptibility of immature and adult brains to seizure effects
    Sheryl R Haut
    Department of Neurology, Comprehensive Epilepsy Management Center, NY, USA
    Lancet Neurol 3:608-17. 2004
    ....
  25. ncbi request reprint New avenue of research: antiepileptic drug and estradiol neuroprotection in epilepsy
    LIBOR VELISEK
    The Saul R Korey of Department of Neurology, Einstein Montefiore Comprehensive Epilepsy Management Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Recent Pat CNS Drug Discov 3:128-37. 2008
    ....
  26. ncbi request reprint Age-related differences in NMDA/metabotropic glutamate receptor binding in rat substantia nigra
    Thomas G Hedberg
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Int J Dev Neurosci 21:95-103. 2003
    ....
  27. ncbi request reprint Low-frequency stimulation of the kindling focus delays basolateral amygdala kindling in immature rats
    LIBOR VELISEK
    Department of Neurology, Albert Einstein College of Medicine, K314, 1410 Pelham Parkway South, Bronx, NY 10461, USA
    Neurosci Lett 326:61-3. 2002
    ..As the kindling and LFS stimulation patterns are similar to those used for induction of long-term potentiation and long-term depression (LTD), respectively, LTD or depotentiation may play a role in the mechanism of action...