Research Topics
Species | JANA VELISKOVASummaryAffiliation: Albert Einstein College of Medicine Country: USA Publications
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Detail Information
Publications
The role of estrogens in seizures and epilepsy: the bad guys or the good guys?J Veliskova
Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
Neuroscience 138:837-44. 2006..Several signaling pathways may be involved in the neuroprotective effects of beta-estradiol on status epilepticus-induced hippocampal damage but at least one of these pathways involves interactions with neuropeptide Y...
Regional neural activity within the substantia nigra during peri-ictal flurothyl generalized seizure stagesJANA VELISKOVA
Department of Neurology, Albert Einstein College of Medicine, AECOM, K314, 1410 Pelham Parkway South, Bronx, NY 10461, USA
Neurobiol Dis 20:752-9. 2005..The postictal suppression state was correlated with changes in the SNR projection targets, specifically the pedunculopontine tegmental nucleus and superior colliculus...- The involvement of the substantia nigra pars reticulata in hypoglycemic seizuresJANA VELISKOVA
Department of Neurology, and Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461, USA
Epilepsia 48:106-8. 2007..These data suggest that during hypoglycemia, the SNR seizure controlling system has different properties than in seizure models not involving a metabolic stress... - Beta-estradiol increases dentate gyrus inhibition in female rats via augmentation of hilar neuropeptide YJANA VELISKOVA
Saul R Korey Department of Neurology, Laboratory of Developmental Epilepsy, Albert Einstein College of Medicine and the Einstein Montefiore Comprehensive Epilepsy Management Center, Bronx, New York 10461, USA
J Neurosci 27:6054-63. 2007.... - Estrogens and epilepsy: why are we so excited?JANA VELISKOVA
The Saul R Korey Department of Neurology and the Dominick P Purpura Department of Neuroscience, Laboratory of Developmental Epilepsy, Albert Einstein College of Medicine, Bronx, NY 10461, USA
Neuroscientist 13:77-88. 2007.... - Sex-specific control of flurothyl-induced tonic-clonic seizures by the substantia nigra pars reticulata during developmentLIBOR VELISEK
Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
Exp Neurol 201:203-11. 2006..Although GABAergic inhibition in the SNR affects tonic-clonic seizures in developing rats, only the NMDA antagonist had consistent anticonvulsant effects throughout development... - Seizures in the developing brainJANA VELISKOVA
Department of Neurology, Montofiore Einstein Epilepsy Management Center, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York 10461, USA
Epilepsia 45:6-12. 2004..By contrast, female SNR does not contain any region that mediates muscimol-related proconvulsant effects. As with the adult, immature female rats do not develop a proconvulsant SNR region at any age... - Circling behavior and [14C]2-deoxyglucose mapping in rats: possible implications for autistic repetitive behaviorsLIBOR VELISEK
Department of Neurology, Albert Einstein College of Medicine, 1410 Pelham Parkway South, Bronx, NY 10461, USA
Neurobiol Dis 18:346-55. 2005.... - Metabolic environment in substantia nigra reticulata is critical for the expression and control of hypoglycemia-induced seizuresLIBOR VELISEK
The Saul R Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
J Neurosci 28:9349-62. 2008..The results suggest that fasting and insulin-induced hypoglycemia can lead to impairment in the function of the SNR, leading thus to hypoglycemic seizures... - Effects of status epilepticus early in life on susceptibility to ischemic injury in adulthoodFilippo S Giorgi
Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA
Epilepsia 46:490-8. 2005..The purpose of this study was to determine the effect of SE induced in immature (15 days old; PN15) male rats, on susceptibility to subsequent transient focal cerebral ischemia induced in adulthood... - The role of substantia nigra pars reticulata in modulating clonic seizures is determined by testosterone levels during the immediate postnatal periodFilippo S Giorgi
The Saul R Korey Department of Neurology, Laboratory of Developmental Epilepsy, Albert Einstein College of Medicine, 1410 Pelham Parkway South, Bronx, NY 10461, USA
Neurobiol Dis 25:73-9. 2007..The data suggest that the PN0-2 period is critical for the development of the seizure-controlling SNR system; the hormonal effect on seizure control is independent from their effect on GABA conductance... - Model of cryptogenic infantile spasms after prenatal corticosteroid primingLIBOR VELISEK
The Saul R Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
Epilepsia 51:145-9. 2010.... - Electrical stimulation of substantia nigra pars reticulata is anticonvulsant in adult and young male ratsLIBOR VELISEK
Department of Neurology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
Exp Neurol 173:145-52. 2002..The data suggest that the SNR may be a candidate site for deep brain stimulation for the treatment of epilepsy... - Sex differences in GABA(A)ergic system in rat substantia nigra pars reticulataTeresa Ravizza
Department of Neurology, Albert Einstein College of Medicine, K311, 1410 Pelham Parkway South, Bronx, NY 10461, USA
Int J Dev Neurosci 21:245-54. 2003.... - Estrogen treatment protects GABA(B) inhibition in the dentate gyrus of female rats after kainic acid-induced status epilepticusLIBOR VELISEK
Department of Neurology K312, Albert Einstein College of Medicine, 1410 Pelham Parkway South, Bronx, NY 10461, U S A
Epilepsia 43:146-51. 2002..Additionally, we determined whether the lost function could be preserved by using estrogen neuroprotection... - Blockade of androgen receptors is sufficient to alter the sexual differentiation of the substantia nigra pars reticulata seizure-controlling networkJames G Heida
Saul R Korey Department of Neurology, Laboratory of Developemental Epilepsy, The Montefiore Einstein Epilepsy Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA
Epileptic Disord 10:8-12. 2008..Thus, activation of androgen receptors is important for the presence of proconvulsant SNR muscimol responses... - Age-dependent consequences of status epilepticus: animal modelsMorris H Scantlebury
Korey Department of Neurology, Albert Einstein College of Medicine, Pelham Parkway South, Kennedy Center, Bronx, NY, USA
Epilepsia 48:75-82. 2007..Better understanding of the pathophysiologic mechanisms underlying the age-specific alterations to the brain induced by SE will lead to the development of novel and effective strategies to improve the deleterious consequences... - Estradiol reduces seizure-induced hippocampal injury in ovariectomized female but not in male ratsAristea S Galanopoulou
Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA
Neurosci Lett 342:201-5. 2003..In males, estradiol increased the total damage score. These findings suggest that the effects of estradiol on seizure threshold and damage may be altered by sex-related differences in the hormonal environment... - Females, their estrogens, and seizuresJANA VELISKOVA
The Saul R Korey Department of Neurology, Albert Einstein College of Medicine, 1410 Pelham Parkway South, Bronx, New York 10461, USA
Epilepsia 51:141-4. 2010..The effects of estrogens on seizures are contradictory. More studies are necessary to determine under which conditions the estrogens have proconvulsant effects and when the estrogens may have beneficial action in patients with epilepsy... - Validation of the rat model of cryptogenic infantile spasmsTamar Chachua
Department of Neurology, Albert Einstein College of Medicine Einstein Montefiore Comprehensive Epilepsy Center, Bronx, New York, USA
Epilepsia 52:1666-77. 2011.... - Developmental aspects of the basal ganglia and therapeutic perspectivesJANA VELISKOVA
Deptartment of Neurology, Albert Einstein College of Medicine, 1410 Pelham Parkway South, Bronx, NY 10461, USA
Epileptic Disord 4:S73-82. 2002..Better understanding of the influence of the endocrine system on brain development and neuronal activity may provide new insight into the treatment of age- and sex-dependent seizure disorders... - Model of infantile spasms induced by N-methyl-D-aspartic acid in prenatally impaired brainLIBOR VELISEK
Saul R Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
Ann Neurol 61:109-19. 2007.... - Age-related differences in NMDA/metabotropic glutamate receptor binding in rat substantia nigraThomas G Hedberg
Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
Int J Dev Neurosci 21:95-103. 2003.... - New avenue of research: antiepileptic drug and estradiol neuroprotection in epilepsyLIBOR VELISEK
The Saul R Korey of Department of Neurology, Einstein Montefiore Comprehensive Epilepsy Management Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA
Recent Pat CNS Drug Discov 3:128-37. 2008.... - Low-frequency stimulation of the kindling focus delays basolateral amygdala kindling in immature ratsLIBOR VELISEK
Department of Neurology, Albert Einstein College of Medicine, K314, 1410 Pelham Parkway South, Bronx, NY 10461, USA
Neurosci Lett 326:61-3. 2002..As the kindling and LFS stimulation patterns are similar to those used for induction of long-term potentiation and long-term depression (LTD), respectively, LTD or depotentiation may play a role in the mechanism of action...