Leonid Tarassishin

Summary

Affiliation: Albert Einstein College of Medicine
Country: USA

Publications

  1. pmc Interferon regulatory factor 3 inhibits astrocyte inflammatory gene expression through suppression of the proinflammatory miR-155 and miR-155*
    Leonid Tarassishin
    Department of Pathology, Albert Einstein College of Medicine, Bronx, NY, USA
    Glia 59:1911-22. 2011
  2. doi Interleukin-1-induced changes in the glioblastoma secretome suggest its role in tumor progression
    Leonid Tarassishin
    Department of Pathology, Albert Einstein College of Medicine, Bronx, NY 10461, United States Electronic address
    J Proteomics 99:152-68. 2014
  3. doi Interferon regulatory factor 3 alters glioma inflammatory and invasive properties
    Leonid Tarassishin
    Department of Pathology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    J Neurooncol 113:185-94. 2013
  4. doi Anti-viral and anti-inflammatory mechanisms of the innate immune transcription factor interferon regulatory factor 3: relevance to human CNS diseases
    Leonid Tarassishin
    Department of Pathology, Forchheimer 726, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    J Neuroimmune Pharmacol 8:132-44. 2013
  5. pmc Interferon regulatory factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathway
    Leonid Tarassishin
    Department of Pathology, Albert Einstein College of Medicine, Bronx, NY, USA
    J Neuroinflammation 8:187. 2011
  6. pmc Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12)
    Hyeon Sook Suh
    Department of Pathology, Albert Einstein College of Medicine, Bronx, New York, United States of America
    PLoS ONE 7:e35115. 2012
  7. pmc The tryptophan metabolite 3-hydroxyanthranilic acid plays anti-inflammatory and neuroprotective roles during inflammation: role of hemeoxygenase-1
    Daniela Krause
    Department of Pathology Neuropathology, Albert Einstein College of Medicine, Bronx, New York, USA
    Am J Pathol 179:1360-72. 2011
  8. doi LPS and IL-1 differentially activate mouse and human astrocytes: Role of CD14
    Leonid Tarassishin
    Department of Pathology, Albert Einstein College of Medicine, Bronx, New York, 10461
    Glia 62:999-1013. 2014
  9. pmc Contribution of pannexin1 to experimental autoimmune encephalomyelitis
    Sarah E Lutz
    Dominick P Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York, USA
    PLoS ONE 8:e66657. 2013

Detail Information

Publications9

  1. pmc Interferon regulatory factor 3 inhibits astrocyte inflammatory gene expression through suppression of the proinflammatory miR-155 and miR-155*
    Leonid Tarassishin
    Department of Pathology, Albert Einstein College of Medicine, Bronx, NY, USA
    Glia 59:1911-22. 2011
    ..Our results demonstrate a novel proinflammatory role for miR-155/miR-155* in human astrocytes and suggest that IRF3 can suppress neuroinflammation through regulating immunomodulatory miRNA expression. © 2011 Wiley-Liss, Inc...
  2. doi Interleukin-1-induced changes in the glioblastoma secretome suggest its role in tumor progression
    Leonid Tarassishin
    Department of Pathology, Albert Einstein College of Medicine, Bronx, NY 10461, United States Electronic address
    J Proteomics 99:152-68. 2014
    ..They further provide novel targets for the glioblastoma intervention...
  3. doi Interferon regulatory factor 3 alters glioma inflammatory and invasive properties
    Leonid Tarassishin
    Department of Pathology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    J Neurooncol 113:185-94. 2013
    ..Together, these data suggest that IRF3 can suppress glioma progression. Agents that promote IRF3 activation and expression (such as IRF3 gene transfer) could be explored as potential future therapy...
  4. doi Anti-viral and anti-inflammatory mechanisms of the innate immune transcription factor interferon regulatory factor 3: relevance to human CNS diseases
    Leonid Tarassishin
    Department of Pathology, Forchheimer 726, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    J Neuroimmune Pharmacol 8:132-44. 2013
    ..We review recent literature on the molecular pathways of IRF3 activation and function of IRF3 and discuss their implications for CNS diseases...
  5. pmc Interferon regulatory factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathway
    Leonid Tarassishin
    Department of Pathology, Albert Einstein College of Medicine, Bronx, NY, USA
    J Neuroinflammation 8:187. 2011
    ....
  6. pmc Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12)
    Hyeon Sook Suh
    Department of Pathology, Albert Einstein College of Medicine, Bronx, New York, United States of America
    PLoS ONE 7:e35115. 2012
    ..In addition to neurons, microglia in vivo express PGRN, but little is known about the regulation of PGRN expression by microglia...
  7. pmc The tryptophan metabolite 3-hydroxyanthranilic acid plays anti-inflammatory and neuroprotective roles during inflammation: role of hemeoxygenase-1
    Daniela Krause
    Department of Pathology Neuropathology, Albert Einstein College of Medicine, Bronx, New York, USA
    Am J Pathol 179:1360-72. 2011
    ..Together, our results demonstrate the novel neuroprotective activity of the tryptophan metabolite 3-HAA and have implications for future therapeutic approaches for neuroinflammatory disorders...
  8. doi LPS and IL-1 differentially activate mouse and human astrocytes: Role of CD14
    Leonid Tarassishin
    Department of Pathology, Albert Einstein College of Medicine, Bronx, New York, 10461
    Glia 62:999-1013. 2014
    ..These results have important implications for translational research of human CNS diseases. GLIA 2014;62:999-1013. ..
  9. pmc Contribution of pannexin1 to experimental autoimmune encephalomyelitis
    Sarah E Lutz
    Dominick P Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York, USA
    PLoS ONE 8:e66657. 2013
    ....