Leonid Tarassishin

Summary

Affiliation: Albert Einstein College of Medicine
Country: USA

Publications

  1. ncbi Interferon regulatory factor 3 inhibits astrocyte inflammatory gene expression through suppression of the proinflammatory miR-155 and miR-155*
    Leonid Tarassishin
    Department of Pathology, Albert Einstein College of Medicine, Bronx, NY, USA
    Glia 59:1911-22. 2011
  2. ncbi Anti-viral and anti-inflammatory mechanisms of the innate immune transcription factor interferon regulatory factor 3: relevance to human CNS diseases
    Leonid Tarassishin
    Department of Pathology, Forchheimer 726, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    J Neuroimmune Pharmacol 8:132-44. 2013
  3. ncbi Interferon regulatory factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathway
    Leonid Tarassishin
    Department of Pathology, Albert Einstein College of Medicine, Bronx, NY, USA
    J Neuroinflammation 8:187. 2011
  4. ncbi Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12)
    Hyeon Sook Suh
    Department of Pathology, Albert Einstein College of Medicine, Bronx, New York, United States of America
    PLoS ONE 7:e35115. 2012
  5. ncbi The tryptophan metabolite 3-hydroxyanthranilic acid plays anti-inflammatory and neuroprotective roles during inflammation: role of hemeoxygenase-1
    Daniela Krause
    Department of Pathology Neuropathology, Albert Einstein College of Medicine, Bronx, New York, USA
    Am J Pathol 179:1360-72. 2011

Detail Information

Publications5

  1. ncbi Interferon regulatory factor 3 inhibits astrocyte inflammatory gene expression through suppression of the proinflammatory miR-155 and miR-155*
    Leonid Tarassishin
    Department of Pathology, Albert Einstein College of Medicine, Bronx, NY, USA
    Glia 59:1911-22. 2011
    ..Our results demonstrate a novel proinflammatory role for miR-155/miR-155* in human astrocytes and suggest that IRF3 can suppress neuroinflammation through regulating immunomodulatory miRNA expression. © 2011 Wiley-Liss, Inc...
  2. ncbi Anti-viral and anti-inflammatory mechanisms of the innate immune transcription factor interferon regulatory factor 3: relevance to human CNS diseases
    Leonid Tarassishin
    Department of Pathology, Forchheimer 726, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    J Neuroimmune Pharmacol 8:132-44. 2013
    ..We review recent literature on the molecular pathways of IRF3 activation and function of IRF3 and discuss their implications for CNS diseases...
  3. ncbi Interferon regulatory factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathway
    Leonid Tarassishin
    Department of Pathology, Albert Einstein College of Medicine, Bronx, NY, USA
    J Neuroinflammation 8:187. 2011
    ....
  4. ncbi Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12)
    Hyeon Sook Suh
    Department of Pathology, Albert Einstein College of Medicine, Bronx, New York, United States of America
    PLoS ONE 7:e35115. 2012
    ..In addition to neurons, microglia in vivo express PGRN, but little is known about the regulation of PGRN expression by microglia...
  5. ncbi The tryptophan metabolite 3-hydroxyanthranilic acid plays anti-inflammatory and neuroprotective roles during inflammation: role of hemeoxygenase-1
    Daniela Krause
    Department of Pathology Neuropathology, Albert Einstein College of Medicine, Bronx, New York, USA
    Am J Pathol 179:1360-72. 2011
    ..Together, our results demonstrate the novel neuroprotective activity of the tryptophan metabolite 3-HAA and have implications for future therapeutic approaches for neuroinflammatory disorders...