DANIEL ROSENBAUM

Summary

Affiliation: Albert Einstein College of Medicine
Country: USA

Publications

  1. ncbi Fas (CD95/APO-1) plays a role in the pathophysiology of focal cerebral ischemia
    D M Rosenbaum
    Department of Neurology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    J Neurosci Res 61:686-92. 2000
  2. ncbi EDG receptors as a potential therapeutic target in retinal ischemia-reperfusion injury
    Sean I Savitz
    Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, USA
    Brain Res 1118:168-75. 2006
  3. ncbi Erythropoietin (epoetin) as a protective factor for the brain
    Samit Malhotra
    Department of Neurology, Albert Einstein College of Medicine, 1410 Pelham Parkway South, KC 303, Bronx, NY 10461, USA
    Curr Atheroscler Rep 6:301-6. 2004
  4. ncbi Functional and morphologic comparison of two methods to produce transient retinal ischemia in the rat
    D M Rosenbaum
    Department of Neurology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    J Neuroophthalmol 21:62-8. 2001
  5. ncbi Hepatocyte growth factor and the risk of ischemic stroke developing among postmenopausal women: results from the Women's Health Initiative
    Swapnil N Rajpathak
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Stroke 41:857-62. 2010
  6. ncbi Choosing the ideal drug for hypertension after ischemic stroke
    Eduard Rozner
    SUNY Downstate Medical Center, Department of Neurology, 450 Clarkson Avenue, Box 1213, Brooklyn, NY 11203, USA
    Curr Hypertens Rep 11:246-52. 2009
  7. ncbi Effects of status epilepticus early in life on susceptibility to ischemic injury in adulthood
    Filippo S Giorgi
    Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA
    Epilepsia 46:490-8. 2005
  8. ncbi Deleterious role of TNF-alpha in retinal ischemia-reperfusion injury
    Samuel Berger
    Department of Neurology, SUNY Downstate Medical Center, Brooklyn, New York11203, USA
    Invest Ophthalmol Vis Sci 49:3605-10. 2008
  9. ncbi Walking speed and risk of incident ischemic stroke among postmenopausal women
    Aileen P McGinn
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, 1300 Morris Park Avenue Belfer 1006A, Bronx, NY 10461, USA
    Stroke 39:1233-9. 2008
  10. ncbi Antithrombotic and thrombolytic therapy for ischemic stroke
    Oriana Cornett
    Department of Neurology, SUNY Downstate, 450 Clarkson Avenue, Brooklyn, NY 11203, USA
    Cardiol Clin 26:251-65, vii. 2008

Research Grants

  1. MECHANISM OF RETINAL ISCHEMIA
    DANIEL ROSENBAUM; Fiscal Year: 2000
  2. MECHANISM OF RETINAL ISCHEMIA
    DANIEL ROSENBAUM; Fiscal Year: 2005

Collaborators

Detail Information

Publications14

  1. ncbi Fas (CD95/APO-1) plays a role in the pathophysiology of focal cerebral ischemia
    D M Rosenbaum
    Department of Neurology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    J Neurosci Res 61:686-92. 2000
    ..These data support the hypothesis that apoptosis plays a role in the pathophysiology of focal cerebral ischemia. Furthermore, these data suggest that fas-mediated apoptosis contributes to this process...
  2. ncbi EDG receptors as a potential therapeutic target in retinal ischemia-reperfusion injury
    Sean I Savitz
    Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, USA
    Brain Res 1118:168-75. 2006
    ..These results suggest that LPA receptor signaling may play an important role in neuroprotection in retinal ischemia-reperfusion injury...
  3. ncbi Erythropoietin (epoetin) as a protective factor for the brain
    Samit Malhotra
    Department of Neurology, Albert Einstein College of Medicine, 1410 Pelham Parkway South, KC 303, Bronx, NY 10461, USA
    Curr Atheroscler Rep 6:301-6. 2004
    ..EPO is thus an ideal compound to study for the potential treatment of a variety of neurologic disorders...
  4. ncbi Functional and morphologic comparison of two methods to produce transient retinal ischemia in the rat
    D M Rosenbaum
    Department of Neurology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    J Neuroophthalmol 21:62-8. 2001
    ....
  5. ncbi Hepatocyte growth factor and the risk of ischemic stroke developing among postmenopausal women: results from the Women's Health Initiative
    Swapnil N Rajpathak
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Stroke 41:857-62. 2010
    ..However, there have been no prospective studies examining the relationship between HGF levels and risk of stroke...
  6. ncbi Choosing the ideal drug for hypertension after ischemic stroke
    Eduard Rozner
    SUNY Downstate Medical Center, Department of Neurology, 450 Clarkson Avenue, Box 1213, Brooklyn, NY 11203, USA
    Curr Hypertens Rep 11:246-52. 2009
    ....
  7. ncbi Effects of status epilepticus early in life on susceptibility to ischemic injury in adulthood
    Filippo S Giorgi
    Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA
    Epilepsia 46:490-8. 2005
    ..The purpose of this study was to determine the effect of SE induced in immature (15 days old; PN15) male rats, on susceptibility to subsequent transient focal cerebral ischemia induced in adulthood...
  8. ncbi Deleterious role of TNF-alpha in retinal ischemia-reperfusion injury
    Samuel Berger
    Department of Neurology, SUNY Downstate Medical Center, Brooklyn, New York11203, USA
    Invest Ophthalmol Vis Sci 49:3605-10. 2008
    ..This study was conducted to further elucidate the role of TNF-alpha and its receptor in an in vivo model of retinal ischemia-reperfusion injury by investigating its effects on retinal histopathology and function...
  9. ncbi Walking speed and risk of incident ischemic stroke among postmenopausal women
    Aileen P McGinn
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, 1300 Morris Park Avenue Belfer 1006A, Bronx, NY 10461, USA
    Stroke 39:1233-9. 2008
    ..However, few studies have investigated the association of walking speed with risk of incident ischemic stroke...
  10. ncbi Antithrombotic and thrombolytic therapy for ischemic stroke
    Oriana Cornett
    Department of Neurology, SUNY Downstate, 450 Clarkson Avenue, Brooklyn, NY 11203, USA
    Cardiol Clin 26:251-65, vii. 2008
    ..The prevention of cardioembolic stroke is best accomplished with oral anticoagulation, barring any contraindications...
  11. ncbi Caveolin-1 deficiency increases cerebral ischemic injury
    Jean Francois Jasmin
    Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, USA
    Circ Res 100:721-9. 2007
    ..Importantly, genetic ablation of the Cav-1 gene in mice results in increased cerebral volume of infarction. Mechanistically, Cav-1 KO ischemic brains showed impaired angiogenesis and increased apoptotic cell death...
  12. ncbi Antithrombotic and thrombolytic therapy for ischemic stroke
    Lenore C Ocava
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Clin Geriatr Med 22:135-54, ix-x. 2006
    ..The prevention of cardioembolic stroke is best accomplished with oral anticoagulation, barring any contraindications...
  13. ncbi Erythropoietin administration protects retinal neurons from acute ischemia-reperfusion injury
    Anna K Junk
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Proc Natl Acad Sci U S A 99:10659-64. 2002
    ..These results further establish EPO as a neuroprotective agent in acute neuronal ischemic injury...
  14. ncbi Ischemic preconditioning attenuates apoptotic cell death in the rat retina
    Cheng Zhang
    Department of Anesthesia and Critical Care, The University of Chicago, Chicago, Illinois 60637, USA
    Invest Ophthalmol Vis Sci 43:3059-66. 2002
    ..CONCLUSIONS: IPC protects against ischemic injury, in part, by diminishing apoptosis-related gene expression and by altering protein phosphorylation...

Research Grants8

  1. MECHANISM OF RETINAL ISCHEMIA
    DANIEL ROSENBAUM; Fiscal Year: 2000
    ..Utilized in this manner, agents that inhibit apoptosis or gene therapy that modifies the cells response to apoptosis may be exciting new approaches to the treatment of retinal ischemia. ..
  2. MECHANISM OF RETINAL ISCHEMIA
    DANIEL ROSENBAUM; Fiscal Year: 2005
    ..b) Multi-modal therapy employing caspase inhibitor(s) and anti-excitotoxic strategies work synergistically toreduce ischemic retinal damage. ..