I Rapin

Summary

Affiliation: Albert Einstein College of Medicine
Country: USA

Publications

  1. doi request reprint What is new in autism?
    Isabelle Rapin
    Saul R Korey Department of Neurology, Department of Pediatrics, and Rose F Kennedy Center for Research in Mental Retardation and Human Development, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Curr Opin Neurol 21:143-9. 2008
  2. doi request reprint Subtypes of language disorders in school-age children with autism
    Isabelle Rapin
    Saul R Korey Department of Neurology, Department of Pediatrics, and Rose F Kennedy Center for Research in Mental Retardation and Human Development, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Dev Neuropsychol 34:66-84. 2009
  3. ncbi request reprint "Auditory neuropathy": physiologic and pathologic evidence calls for more diagnostic specificity
    Isabelle Rapin
    Saul R Korey Department of Neurology, K 807, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Int J Pediatr Otorhinolaryngol 67:707-28. 2003
  4. doi request reprint Autism: definition, neurobiology, screening, diagnosis
    Isabelle Rapin
    Saul R Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA
    Pediatr Clin North Am 55:1129-46, viii. 2008
  5. ncbi request reprint Update on the language disorders of individuals on the autistic spectrum
    Isabelle Rapin
    Saul R Korey Department of Neurology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY, USA
    Brain Dev 25:166-72. 2003
  6. ncbi request reprint Cockayne syndrome and xeroderma pigmentosum
    I Rapin
    Department of Neurology, Rose F Kennedy Center for Research in Mental Retardation and Human Development, Albert Einstein College of Medicine, Bronx, NY, USA
    Neurology 55:1442-9. 2000
  7. ncbi request reprint Consistency in the ratings of behaviors of communicatively impaired autistic and non-autistic preschool children
    I Rapin
    Room 807 Kennedy Center, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461 USA
    Eur Child Adolesc Psychiatry 8:214-24. 1999
  8. pmc Cockayne syndrome in adults: review with clinical and pathologic study of a new case
    Isabelle Rapin
    Albert Einstein College of Medicine, Bronx, NY 10461, USA
    J Child Neurol 21:991-1006. 2006
  9. ncbi request reprint Appropriate investigations for clinical care versus research in children with autism
    I Rapin
    Saul R Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA
    Brain Dev 21:152-6. 1999
  10. ncbi request reprint The influence of premorbid language skills and behavior on language recovery in children with verbal auditory agnosia
    S K Klein
    Saul R Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA
    J Child Neurol 15:36-43. 2000

Collaborators

Detail Information

Publications31

  1. doi request reprint What is new in autism?
    Isabelle Rapin
    Saul R Korey Department of Neurology, Department of Pediatrics, and Rose F Kennedy Center for Research in Mental Retardation and Human Development, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Curr Opin Neurol 21:143-9. 2008
    ..This review highlights the topics within the growing autism literature that are shaping current thinking on autism and advancing research and clinical understanding of autism spectrum disorders...
  2. doi request reprint Subtypes of language disorders in school-age children with autism
    Isabelle Rapin
    Saul R Korey Department of Neurology, Department of Pediatrics, and Rose F Kennedy Center for Research in Mental Retardation and Human Development, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Dev Neuropsychol 34:66-84. 2009
    ..The clusters refute a single language disorder in autism and are consonant with earlier-defined clinical subtypes...
  3. ncbi request reprint "Auditory neuropathy": physiologic and pathologic evidence calls for more diagnostic specificity
    Isabelle Rapin
    Saul R Korey Department of Neurology, K 807, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Int J Pediatr Otorhinolaryngol 67:707-28. 2003
    ....
  4. doi request reprint Autism: definition, neurobiology, screening, diagnosis
    Isabelle Rapin
    Saul R Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA
    Pediatr Clin North Am 55:1129-46, viii. 2008
    ..Early recognition of the social deficits that characterize autism is key to maximizing the potential of these children...
  5. ncbi request reprint Update on the language disorders of individuals on the autistic spectrum
    Isabelle Rapin
    Saul R Korey Department of Neurology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY, USA
    Brain Dev 25:166-72. 2003
    ..Clearly, social and cognitive disorders alone provide an inadequate explanation for the range of language deficits in autism...
  6. ncbi request reprint Cockayne syndrome and xeroderma pigmentosum
    I Rapin
    Department of Neurology, Rose F Kennedy Center for Research in Mental Retardation and Human Development, Albert Einstein College of Medicine, Bronx, NY, USA
    Neurology 55:1442-9. 2000
    ....
  7. ncbi request reprint Consistency in the ratings of behaviors of communicatively impaired autistic and non-autistic preschool children
    I Rapin
    Room 807 Kennedy Center, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461 USA
    Eur Child Adolesc Psychiatry 8:214-24. 1999
    ....
  8. pmc Cockayne syndrome in adults: review with clinical and pathologic study of a new case
    Isabelle Rapin
    Albert Einstein College of Medicine, Bronx, NY 10461, USA
    J Child Neurol 21:991-1006. 2006
    ....
  9. ncbi request reprint Appropriate investigations for clinical care versus research in children with autism
    I Rapin
    Saul R Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA
    Brain Dev 21:152-6. 1999
    ..This is not true, of course, in the context of a hypothesis-driven, approved research protocol where collecting standardized data and applying the most up-to-date research technologies is appropriate...
  10. ncbi request reprint The influence of premorbid language skills and behavior on language recovery in children with verbal auditory agnosia
    S K Klein
    Saul R Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA
    J Child Neurol 15:36-43. 2000
    ..This study emphasizes the importance of assessing premorbid language and behavior in predicting recovery of language skills in children with language-epilepsy syndromes...
  11. ncbi request reprint Autistic disorder versus other pervasive developmental disorders in young children: same or different?
    D A Allen
    Division of Child Psychiatry, Department of Psychiatry, Albert Einstein College of Medicine, Bronx, NY, USA
    Eur Child Adolesc Psychiatry 10:67-78. 2001
    ....
  12. ncbi request reprint Language regression in childhood
    S Shinnar
    Department of Neurology, the Comprehensive Epilepsy Management Center at Montifiore Medical Center, Albert Einstein College of Medicine, Bronx, NY 10467, USA
    Pediatr Neurol 24:183-9. 2001
    ..Early identification and referral of these children is necessary to allow for diagnosis and intervention...
  13. ncbi request reprint Children with inadequate language development: management guidelines for otolaryngologists
    I Rapin
    Saul R Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461
    Int J Pediatr Otorhinolaryngol 16:189-98. 1988
    ..Guidelines on when to become concerned and what to do about such children are provided. Early diagnosis is essential in order to provide remedial education at the language learning age when intervention is likely to be most efficacious...
  14. ncbi request reprint Xeroderma pigmentosum/cockayne syndrome complex: first neuropathological study and review of eight other cases
    Y Lindenbaum
    Saul R. Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Eur J Paediatr Neurol 5:225-42. 2001
    ....
  15. ncbi request reprint Adult onset pigmentary orthochromatic leukodystrophy with ovarian dysgenesis
    J Verghese
    Department of Neurology, Kennedy Center for Research in Mental Retardation and Human Development, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Eur J Neurol 9:663-70. 2002
    ..POLD is a rare cause of adult-onset leukodystrophy presenting with dementia. Ovarian dysgenesis is extremely rare in the absence of demonstrable chromosomal abnormalities and extends the clinical spectrum of POLD...
  16. ncbi request reprint Auditory neuropathy: a biologically inappropriate label unless acoustic nerve involvement is documented
    Isabelle Rapin
    Saul R Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA
    J Am Acad Audiol 17:147-50. 2006
  17. ncbi request reprint Joubert syndrome: monozygotic twins with discordant phenotypes
    H R Raynes
    Department of Neurology, Jacobi and Montefiore Medical Centers, Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10467, USA
    J Child Neurol 14:649-54; discussion 669-72 discussio. 1999
    ..Phenotypic differences between the twins could be attributable to postzygotic unequal division of the inner cell mass, unequal sharing of the venous return from a monochorionic placenta, mosaicism, or a mutation of a modifying gene...
  18. ncbi request reprint Etiology and pathophysiology of autistic behavior: clues from two cases with an unusual variant of neuroaxonal dystrophy
    K M Weidenheim
    Department of Pathology Neuropathology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York 10467, USA
    J Child Neurol 16:809-19. 2001
    ..Neuroaxonal dystrophy should be included in the list of diseases that may be found in persons with autism...
  19. ncbi request reprint Clinical characteristics of language regression in children
    Sy Wilson
    Saul R Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Dev Med Child Neurol 45:508-14. 2003
    ..Improvement was more likely in the 49% who were entirely developmentally normal before the regression. We conclude that language regression in childhood is a serious disorder with significant long-term morbidity...
  20. ncbi request reprint Epileptiform EEG abnormalities in children with language regression
    K A McVicar
    Department of Neurology, The Comprehensive Epilepsy Management Center, Montefiore Medical Center, The Albert Einstein College of Medicine, Bronx, NY, USA
    Neurology 65:129-31. 2005
    ..002) and also a higher rate of clinical seizures (33% vs 8%, p < 0.001). EEG abnormalities in the LR only group were also more prominent. This suggests two subtypes of language regression...
  21. doi request reprint Motor stereotypies in children with autism and other developmental disorders
    Sylvie Goldman
    Saul R Korey Department of Neurology and Rose F Kennedy Center for Research in Mental Retardation and Human Development, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Dev Med Child Neurol 51:30-8. 2009
    ..Stereotypies are environmentally modulated movement disorders, some highly suggestive, but not pathognomonic, of autism. Their underlying brain basis and genetic correlates need investigation...
  22. doi request reprint Neuropathology of Cockayne syndrome: Evidence for impaired development, premature aging, and neurodegeneration
    Karen M Weidenheim
    Department of Pathology, Albert Einstein College of Medicine, Bronx, NY, United States
    Mech Ageing Dev 130:619-36. 2009
    ..Understanding the genetics, biochemical, and cellular pathophysiology of these disorders remains fragmentary...
  23. ncbi request reprint The autistic-spectrum disorders
    Isabelle Rapin
    Albert Einstein College of Medicine, Bronx, NY 10461, USA
    N Engl J Med 347:302-3. 2002
  24. pmc Convulsing toward the pathophysiology of autism
    Roberto Tuchman
    Department of Neurology, University of Miami, Miami Children s Hospital, Dan Marino Center, 2900 South Commerce Parkway, Weston, FL, USA
    Brain Dev 31:95-103. 2009
    ..The autism-epilepsy phenotype provides a novel model to the study of interventions that may have a positive modulating effects on social cognitive outcome...
  25. ncbi request reprint Epilepsy in autism
    Roberto Tuchman
    Miami Children s Hospital, Dan Marino Center, Department of Neurology, Weston, FL 33331, USA
    Lancet Neurol 1:352-8. 2002
    ..There is no evidence-based treatment recommendation for individuals with autism, regression, and subclinical epilepsy. Double-blind studies with sufficient power to resolve this issue are urgently needed...
  26. ncbi request reprint Contribution of child neurology to the investigation and care of children with developmental disorders
    Isabelle Rapin
    Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Pediatr Neurol 29:374-5. 2003
  27. ncbi request reprint Frequency of gastrointestinal symptoms in children with autistic spectrum disorders and association with family history of autoimmune disease
    Maria Valicenti-McDermott
    Children s Evaluation and Rehabilitation Center, Bronx, New York 10461, USA
    J Dev Behav Pediatr 27:S128-36. 2006
    ..Children with ASD have a higher rate of GI symptoms than children with either typical development or other DDs. In this study, there was no association between a family history of autoimmune disease and GI symptoms in children with ASD...
  28. ncbi request reprint The genetics of autism
    Rebecca Muhle
    Class of 2004, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Pediatrics 113:e472-86. 2004
    ..Future clinically useful insights and potential medications depend on identifying these genes and elucidating the influences of their products on brain development and physiology...
  29. ncbi request reprint Value and limitations of preschool cognitive tests, with an emphasis on longitudinal study of children on the autistic spectrum
    Isabelle Rapin
    Brain Dev 25:546-8. 2003
  30. ncbi request reprint Legitimacy of comparing fragile X with autism questioned
    Isabelle Rapin
    J Autism Dev Disord 32:60-1. 2002
  31. ncbi request reprint Sensorimotor performance in school-age children with autism, developmental language disorder, or low IQ
    David E Mandelbaum
    Department of Clinical Neurosciences, Brown Medical School, Providence, RI, USA
    Dev Med Child Neurol 48:33-9. 2006
    ..Inability/unwillingness to perform tasks was much more frequent in LoAD than LoIQ children...