G A Morrill
Affiliation: Albert Einstein College of Medicine
- Morrill G, Schatz F, Kostellow A, Bloch E. Gonadotropin stimulation of steroid synthesis and metabolism in the Rana pipiens ovarian follicle: sequential changes in endogenous steroids during ovulation, fertilization and cleavage stages. J Steroid Biochem Mol Biol. 2006;99:129-38 pubmed..The progesterone metabolites formed during meiosis are largely released at fertilization. ..
- Morrill G, DOWD T, Kostellow A, Gupta R. Progesterone-induced changes in the phosphoryl potential during the meiotic divisions in amphibian oocytes: role of Na/K-ATPase. BMC Dev Biol. 2011;11:67 pubmed publisher..Phosvitin serves as a major energy source during fertilization and early cleavage stages and is also a storage site for cations (e.g. Na+, K+, Ca2+, Fe2+/3+) essential for embryonic development. ..
- Morrill G, Kostellow A, Askari A. Progesterone binding to the alpha1-subunit of the Na/K-ATPase on the cell surface: insights from computational modeling. Steroids. 2008;73:27-40 pubmed..Peptide flexibility undergoes a maximal transition near the midway point in the M1-M2 loop, suggesting that folding occurs within the loop, which further stabilizes progesterone binding...
- Morrill G, Erlichman J, Gutierrez Juarez R, Kostellow A. The steroid-binding subunit of the Na/K-ATPase as a progesterone receptor on the amphibian oocyte plasma membrane. Steroids. 2005;70:933-45 pubmed..Progesterone may thus act in part through the plasma membrane Na/K-ATPase signaling system...