Michal L Melamed

Summary

Affiliation: Albert Einstein College of Medicine
Country: USA

Publications

  1. pmc Serum 25-hydroxyvitamin D levels and the prevalence of peripheral arterial disease: results from NHANES 2001 to 2004
    Michal L Melamed
    Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA
    Arterioscler Thromb Vasc Biol 28:1179-85. 2008
  2. pmc 25-hydroxyvitamin D levels and the risk of mortality in the general population
    Michal L Melamed
    Division of Nephrology, Department of Medicine, Albert Einstein College of Medicine, 1300 Morris Park Ave, Ullmann 615, Bronx, NY 10461, USA
    Arch Intern Med 168:1629-37. 2008
  3. pmc 25-hydroxyvitamin D levels, race, and the progression of kidney disease
    Michal L Melamed
    Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    J Am Soc Nephrol 20:2631-9. 2009
  4. doi request reprint Raloxifene, a selective estrogen receptor modulator, is renoprotective: a post-hoc analysis
    Michal L Melamed
    Department of Medicine, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York, USA
    Kidney Int 79:241-9. 2011
  5. ncbi request reprint Third-generation parathyroid hormone assays and all-cause mortality in incident dialysis patients: the CHOICE study
    Michal L Melamed
    Departments of Medicine and Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA
    Nephrol Dial Transplant 23:1650-8. 2008
  6. pmc Serum alkaline phosphatase and phosphate and risk of mortality and hospitalization
    Matthew Abramowitz
    Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York, USA
    Clin J Am Soc Nephrol 5:1064-71. 2010
  7. pmc Association of serum intact parathyroid hormone with lower estimated glomerular filtration rate
    Paul Muntner
    Department of Community and Preventive Medicine, Mount Sinai School of Medicine, 1 Gustave L Levy Place, New York, NY 10016, USA
    Clin J Am Soc Nephrol 4:186-94. 2009
  8. pmc The serum anion gap is altered in early kidney disease and associates with mortality
    Matthew K Abramowitz
    Division of Nephrology, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Kidney Int 82:701-9. 2012
  9. pmc Serum phosphate levels and risk of infection in incident dialysis patients
    Laura C Plantinga
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Clin J Am Soc Nephrol 3:1398-406. 2008
  10. pmc Peripheral vascular disease-related procedures in dialysis patients: predictors and prognosis
    Laura C Plantinga
    Department of Medicine, San Francisco General Hospital and University of California, San Francisco, California, USA
    Clin J Am Soc Nephrol 4:1637-45. 2009

Detail Information

Publications39

  1. pmc Serum 25-hydroxyvitamin D levels and the prevalence of peripheral arterial disease: results from NHANES 2001 to 2004
    Michal L Melamed
    Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA
    Arterioscler Thromb Vasc Biol 28:1179-85. 2008
    ..The purpose of this study was to determine the association between 25-hydroxyvitamin D (25(OH)D) levels and the prevalence of peripheral arterial disease (PAD) in the general United States population...
  2. pmc 25-hydroxyvitamin D levels and the risk of mortality in the general population
    Michal L Melamed
    Division of Nephrology, Department of Medicine, Albert Einstein College of Medicine, 1300 Morris Park Ave, Ullmann 615, Bronx, NY 10461, USA
    Arch Intern Med 168:1629-37. 2008
    ..However, whether low serum 25(OH)D levels are associated with mortality in the general population is unknown...
  3. pmc 25-hydroxyvitamin D levels, race, and the progression of kidney disease
    Michal L Melamed
    Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    J Am Soc Nephrol 20:2631-9. 2009
    ..Low 25(OH)D levels may account for a substantial proportion of the increased risk for ESRD experienced by black individuals...
  4. doi request reprint Raloxifene, a selective estrogen receptor modulator, is renoprotective: a post-hoc analysis
    Michal L Melamed
    Department of Medicine, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York, USA
    Kidney Int 79:241-9. 2011
    ..Thus, treatment with raloxifene was safe and renoprotective. Clinical trials of raloxifene in post-menopausal women with kidney disease designed to look at kidney outcomes are needed to confirm these findings...
  5. ncbi request reprint Third-generation parathyroid hormone assays and all-cause mortality in incident dialysis patients: the CHOICE study
    Michal L Melamed
    Departments of Medicine and Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA
    Nephrol Dial Transplant 23:1650-8. 2008
    ..There has been controversy about the utility of new third-generation parathyroid hormone (PTH) assays measuring only 1-84 PTH, with few large studies comparing second- and third-generation PTH measurements in patients with ESRD...
  6. pmc Serum alkaline phosphatase and phosphate and risk of mortality and hospitalization
    Matthew Abramowitz
    Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York, USA
    Clin J Am Soc Nephrol 5:1064-71. 2010
    ..A retrospective cohort study was conducted to test these associations in outpatients with an estimated GFR > or =60 ml/min/1.73 m(2)...
  7. pmc Association of serum intact parathyroid hormone with lower estimated glomerular filtration rate
    Paul Muntner
    Department of Community and Preventive Medicine, Mount Sinai School of Medicine, 1 Gustave L Levy Place, New York, NY 10016, USA
    Clin J Am Soc Nephrol 4:186-94. 2009
    ..The prevalence of mineral metabolism abnormalities is almost universal in stage 5 chronic kidney disease (CKD), but the presence of abnormalities in milder CKD is not well characterized...
  8. pmc The serum anion gap is altered in early kidney disease and associates with mortality
    Matthew K Abramowitz
    Division of Nephrology, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Kidney Int 82:701-9. 2012
    ..Further study is needed to identify the unmeasured anions and to determine their physiological significance...
  9. pmc Serum phosphate levels and risk of infection in incident dialysis patients
    Laura C Plantinga
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Clin J Am Soc Nephrol 3:1398-406. 2008
    ..Hyperphosphatemia is highly prevalent in dialysis patients and may be associated with immune dysfunction. The association of serum phosphate level with infection remains largely unexamined...
  10. pmc Peripheral vascular disease-related procedures in dialysis patients: predictors and prognosis
    Laura C Plantinga
    Department of Medicine, San Francisco General Hospital and University of California, San Francisco, California, USA
    Clin J Am Soc Nephrol 4:1637-45. 2009
    ..Peripheral vascular disease (PVD) is prevalent among dialysis patients, and many dialysis patients undergo PVD-related procedures. We aimed to examine the risk factors for and prognosis after such procedures in the dialysis setting...
  11. doi request reprint Uremic memory: the role of acute kidney injury in long-term outcomes
    Ladan Golestaneh
    Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York, USA
    Kidney Int 76:813-4. 2009
    ..Lo et al. correlate AKI with long-term outcomes. The concept of 'uremic memory' sheds light on the importance of AKI and its permanent imprint. The focus of research should be on prevention of an episode of AKI, when possible...
  12. ncbi request reprint eGFR: is it ready for early identification of CKD?
    Michal L Melamed
    Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Clin J Am Soc Nephrol 3:1569-72. 2008
    ..Reporting of eGFR is only one tool in attempting to rectify this latter problem. Nephrologists need to educate patients and their primary care colleagues in the use of this tool...
  13. pmc Lower serum bicarbonate and a higher anion gap are associated with lower cardiorespiratory fitness in young adults
    Matthew K Abramowitz
    Division of Nephrology, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Kidney Int 81:1033-42. 2012
    ..Thus, lower levels of serum bicarbonate and higher levels of anion gap are associated with lower cardiorespiratory fitness in adults aged 20-49 years in the general population...
  14. pmc Association of glucocorticoid use and low 25-hydroxyvitamin D levels: results from the National Health and Nutrition Examination Survey (NHANES): 2001-2006
    Amy L Skversky
    Division of Pediatric Nephrology, Albert Einstein College of Medicine, The Children s Hospital at Montefiore, Bronx, New York 10467, USA
    J Clin Endocrinol Metab 96:3838-45. 2011
    ..The association between steroid use and 25-hydroxyvitamin D [25(OH)D] deficiency has not been confirmed in large population-based studies, and currently there are no specific vitamin D recommendations for steroid users...
  15. ncbi request reprint Statin use and sepsis events [corrected] in patients with chronic kidney disease
    Rajesh Gupta
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    JAMA 297:1455-64. 2007
    ..Patients with chronic kidney disease are at high risk for sepsis and sepsis-related mortality...
  16. pmc Prevalence and associations of 25-hydroxyvitamin D deficiency in US children: NHANES 2001-2004
    Juhi Kumar
    Children s Hospital at Montefiore, Bronx, New York, USA
    Pediatrics 124:e362-70. 2009
    ..To determine the prevalence of 25-hydroxyvitamin D (25[OH]D) deficiency and associations between 25(OH)D deficiency and cardiovascular risk factors in children and adolescents...
  17. pmc Relationship of impaired olfactory function in ESRD to malnutrition and retained uremic molecules
    Amanda C Raff
    Department of Medicine, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY, USA
    Am J Kidney Dis 52:102-10. 2008
    ..This study examines the relationship of impaired olfactory function to malnutrition and levels of the retained uremic solutes monomethylamine, ethylamine, indoxyl sulfate, and P-cresol sulfate...
  18. ncbi request reprint Role of vitamin D receptor activation in racial disparities in kidney disease outcomes
    Utibe Essien
    Departments of Medicine and Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY
    Semin Nephrol 33:416-24. 2013
    ..In this review, we examine the evidence linking 25(OH)D to outcomes and the possibility that differential 25(OH)D may explain certain racial differences in outcomes. ..
  19. doi request reprint A zebrafish model for uremic toxicity: role of the complement pathway
    Nathaniel Berman
    Weill Cornell Medical College, New York, NY, USA
    Blood Purif 35:265-9. 2013
    ..Together these data lend support to the hypothesis that at least some uremic toxicities may be mediated by complement. ..
  20. pmc Effects of oral sodium bicarbonate in patients with CKD
    Matthew K Abramowitz
    Division of Nephrology, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA
    Clin J Am Soc Nephrol 8:714-20. 2013
    ..In CKD patients with mild acidosis, this study evaluated the dose-response relationship of alkali with serum bicarbonate, its side effect profile, and its effect on muscle strength...
  21. pmc Vitamin D therapy in chronic kidney disease and end stage renal disease
    Michal L Melamed
    Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Clin J Am Soc Nephrol 7:358-65. 2012
    ..This review discusses observational and available clinical trial evidence about the effects of both calcitriol and vitamin D analogs (active) and ergocalciferol and cholecalciferol (nutritional) vitamin D in patients with CKD and ESRD...
  22. ncbi request reprint Moderate chronic kidney disease and cognitive function in adults 20 to 59 years of age: Third National Health and Nutrition Examination Survey (NHANES III)
    Susan M Hailpern
    Department of Epidemiology, Albert Einstein College of Medicine, Belfer 1006A, Bronx, NY 10461, USA
    J Am Soc Nephrol 18:2205-13. 2007
    ..73 m(2), was significantly associated with poorer performance in visual attention and learning/concentration...
  23. pmc Methylamine clearance by haemodialysis is low
    Manish P Ponda
    Division of Nephrology, Department of Medicine, Albert Einstein College of Medicine, Room 615, Ullmann Building, 1300 Morris Park Ave, Bronx, NY 10461, USA
    Nephrol Dial Transplant 25:1608-13. 2010
    ..However, urea is relatively non-toxic and has properties distinct from large classes of other retained solutes. In particular, intracellularly sequestered solutes are likely to behave differently than urea...
  24. ncbi request reprint Vitamin D and cardiovascular disease risk
    Erin D Michos
    Department of Medicine, Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
    Curr Opin Clin Nutr Metab Care 11:7-12. 2008
    ..25-Hydroxyvitamin D deficiency has been identified as a potential novel cardiovascular disease risk factor. This review outlines what is known about the association of 25-hydroxyvitamin D levels and cardiovascular disease risk...
  25. doi request reprint Vitamin D status and risk of cardiovascular events: lessons learned via systematic review and meta-analysis
    Seth I Sokol
    Department of Medicine, Division of Cardiology, Jacobi Medical Center and the Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Cardiol Rev 19:192-201. 2011
    ..These findings underscore the importance of critical appraisal of the literature, looking beyond reported risk estimates before translating results into clinical practice...
  26. pmc Vitamin D levels and food and environmental allergies in the United States: results from the National Health and Nutrition Examination Survey 2005-2006
    Shimi Sharief
    Department of Medicine, Rush University Medical Center, Chicago, IL, USA
    J Allergy Clin Immunol 127:1195-202. 2011
    ..Previous research supports a possible link between low vitamin D levels and atopic disease. However, the association between low vitamin D levels and total and allergen-specific IgE levels has not been studied...
  27. doi request reprint Treatment of chronic kidney disease
    Jeffrey M Turner
    Nephrology Division, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA
    Kidney Int 81:351-62. 2012
    ....
  28. pmc Family history of exceptional longevity is associated with lower serum uric acid levels in Ashkenazi Jews
    Jennifer Yi Chun Lai
    Division of Nephrology, Department of Internal Medicine, School of Medicine, University of Michigan, Ann Arbor, Michigan 48105, USA
    J Am Geriatr Soc 60:745-50. 2012
    ..To test whether lower serum uric acid (UA) levels are associated with longevity independent of renal function...
  29. doi request reprint Staging of chronic kidney disease: time for a course correction
    Carolyn Bauer
    Department of Medicine, Division of Nephrology, Albert Einstein College of Medicine, Bronx, New York, USA
    J Am Soc Nephrol 19:844-6. 2008
    ..These changes would allow identification and treatment of clinically relevant disease and avoidance of what can seem exaggerated prevalence estimates...
  30. pmc Individuals with exceptional longevity manifest a delayed association between vitamin d insufficiency and cognitive impairment
    Sofiya Milman
    Division of Endocrinology, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York Institute for Aging Research, Albert Einstein College of Medicine, Bronx, New York
    J Am Geriatr Soc 62:153-8. 2014
    ..To define vitamin D levels and their association with cognition in subjects with exceptional longevity...
  31. doi request reprint Vitamin D and cardiovascular disease and cancer: not too much and not too little? The need for clinical trials
    Michal L Melamed
    Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Womens Health (Lond Engl) 7:419-24. 2011
    ..On going clinical trials should aid in elucidating the optimal levels of 25-hydroxyvitamin D for numerous health outcomes...
  32. ncbi request reprint Racial disparities in the optimal delivery of chronic kidney disease care
    Neil R Powe
    Department of Medicine, Johns Hopkins School of Medicine, 2024 East Monument Street, Suite 2 600, Baltimore, MD 21205, USA
    Med Clin North Am 89:475-88. 2005
    ....
  33. doi request reprint Serum bicarbonate levels and the progression of kidney disease: a cohort study
    Samir N Shah
    Albert Einstein College of Medicine Montefiore Medical Center, Bronx, NY, USA
    Am J Kidney Dis 54:270-7. 2009
    ..Animal models of kidney disease have linked metabolic acidosis with renal damage. The role of low serum bicarbonate levels in kidney disease progression in humans has not been studied...
  34. doi request reprint Ionizing radiation exposure: another underrecognized risk factor for poor health outcomes in dialysis patients
    Michal L Melamed
    Division of Nephrology, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Kidney Int 78:724-5. 2010
    ..Novel risk factors have been identified that may help explain these risk elevations. We discuss medical radiation exposure as a novel risk factor in dialysis patients and suggest the need for future research on this topic...
  35. pmc Association of serum bicarbonate levels with gait speed and quadriceps strength in older adults
    Matthew K Abramowitz
    Division of Nephrology, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Am J Kidney Dis 58:29-38. 2011
    ..However, the association of acidosis with functional outcomes has not been examined on a population-based level...
  36. ncbi request reprint Combined percutaneous mechanical and chemical thrombectomy for renal vein thrombosis in kidney transplant recipients
    Michal L Melamed
    Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
    Am J Transplant 5:621-6. 2005
    ....
  37. ncbi request reprint Risk factors for renal failure among 72 consecutive patients with rhabdomyolysis related to illicit drug use
    Derek M Fine
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Am J Med 117:607-10. 2004
  38. pmc Expression of Notch pathway proteins correlates with albuminuria, glomerulosclerosis, and renal function
    Mariana Murea
    Department of Medicine Nephrology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Kidney Int 78:514-22. 2010
    ..Hence, our results raise the possibility that Notch pathway activation is a common mechanism in the pathophysiology of a wide range of acquired renal diseases...
  39. pmc Phosphate levels and blood pressure in incident hemodialysis patients: a longitudinal study
    Cindy Xin Huang
    Johns Hopkins Sinai Hospital Program in Internal Medicine, Baltimore, MD, USA
    Adv Chronic Kidney Dis 15:321-31. 2008
    ..The effect of rigorous control of serum phosphate levels on arterial stiffness and blood pressure should be studied in clinical trials...

Research Grants3

  1. Racial disparaties in ESRD: Bone Disease & Morbidity
    Michal Melamed; Fiscal Year: 2005
    ..abstract_text> ..
  2. Racial Disparities in Chronic Kidney Disease and Vitamin D: Are they related?
    Michal Melamed; Fiscal Year: 2007
    ..This K23 grant will allow me to develop my career through advanced formal coursework, intensive mentoring and the design, planning and conduct of a randomized clinical trial. ..