Hayley M McDaid

Summary

Affiliation: Albert Einstein College of Medicine
Country: USA

Publications

  1. ncbi request reprint Enhancement of the therapeutic efficacy of taxol by the mitogen-activated protein kinase kinase inhibitor CI-1040 in nude mice bearing human heterotransplants
    Hayley M McDaid
    Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Cancer Res 65:2854-60. 2005
  2. ncbi request reprint Targeting protein translation in human non small cell lung cancer via combined MEK and mammalian target of rapamycin suppression
    Marie Emmanuelle Legrier
    Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Cancer Res 67:11300-8. 2007
  3. pmc Resistance to discodermolide, a microtubule-stabilizing agent and senescence inducer, is 4E-BP1-dependent
    Suzan K Chao
    Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Proc Natl Acad Sci U S A 108:391-6. 2011
  4. pmc Exploiting MEK inhibitor-mediated activation of ERα for therapeutic intervention in ER-positive ovarian carcinoma
    June Y Hou
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology and Women s Health, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, USA
    PLoS ONE 8:e54103. 2013
  5. ncbi request reprint Potentiation of taxol efficacy and by discodermolide in ovarian carcinoma xenograft-bearing mice
    Gloria S Huang
    Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Clin Cancer Res 12:298-304. 2006
  6. doi request reprint High expression of class III β-tubulin predicts good response to neoadjuvant taxane and doxorubicin/cyclophosphamide-based chemotherapy in estrogen receptor-negative breast cancer
    Yihong Wang
    Department of Pathology, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY, USA
    Clin Breast Cancer 13:103-8. 2013
  7. doi request reprint Characterization of a human βV-tubulin antibody and expression of this isotype in normal and malignant human tissue
    Suzan K Chao
    Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Cytoskeleton (Hoboken) 69:566-76. 2012
  8. pmc Insights into 4E-BP1 and p53 mediated regulation of accelerated cell senescence
    Suzan K Chao
    Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Oncotarget 2:89-98. 2011

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Enhancement of the therapeutic efficacy of taxol by the mitogen-activated protein kinase kinase inhibitor CI-1040 in nude mice bearing human heterotransplants
    Hayley M McDaid
    Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Cancer Res 65:2854-60. 2005
    ..These findings are significant and indicate that this combination may have broad therapeutic applications in a diverse range of lung tumors with different intrinsic chemosensitivities...
  2. ncbi request reprint Targeting protein translation in human non small cell lung cancer via combined MEK and mammalian target of rapamycin suppression
    Marie Emmanuelle Legrier
    Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Cancer Res 67:11300-8. 2007
    ..These data (a) provide evidence that both pathways converge on factors that regulate translation initiation and (b) support therapeutic strategies in lung cancer that simultaneously suppress the RAS and AKT signaling network...
  3. pmc Resistance to discodermolide, a microtubule-stabilizing agent and senescence inducer, is 4E-BP1-dependent
    Suzan K Chao
    Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Proc Natl Acad Sci U S A 108:391-6. 2011
    ..Furthermore, the stability of p53 was enhanced in AD32 cells. Our studies propose a role for 4E-BP1 as a regulator of discodermolide-induced accelerated senescence...
  4. pmc Exploiting MEK inhibitor-mediated activation of ERα for therapeutic intervention in ER-positive ovarian carcinoma
    June Y Hou
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology and Women s Health, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, USA
    PLoS ONE 8:e54103. 2013
    ..Thus, we demonstrate that exploiting adaptive feedback after MEKi can be used to sensitize ERα-positive tumors to hormonal therapy, and propose that this strategy may have broader clinical utility in ERα-positive ovarian carcinoma...
  5. ncbi request reprint Potentiation of taxol efficacy and by discodermolide in ovarian carcinoma xenograft-bearing mice
    Gloria S Huang
    Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Clin Cancer Res 12:298-304. 2006
    ..To evaluate the drug combination of discodermolide and Taxol in human ovarian cancer cells and in an in vivo model of ovarian carcinoma...
  6. doi request reprint High expression of class III β-tubulin predicts good response to neoadjuvant taxane and doxorubicin/cyclophosphamide-based chemotherapy in estrogen receptor-negative breast cancer
    Yihong Wang
    Department of Pathology, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY, USA
    Clin Breast Cancer 13:103-8. 2013
    ..The objective of this explorative study was to determine whether βΙΙΙ-tubulin expression in breast cancer correlated with pathologic characteristics and whether its expression was predictive of response to neoadjuvant chemotherapy...
  7. doi request reprint Characterization of a human βV-tubulin antibody and expression of this isotype in normal and malignant human tissue
    Suzan K Chao
    Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Cytoskeleton (Hoboken) 69:566-76. 2012
    ..Thus, βV-tubulin expression is a potentially promising prognostic marker of malignancy...
  8. pmc Insights into 4E-BP1 and p53 mediated regulation of accelerated cell senescence
    Suzan K Chao
    Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Oncotarget 2:89-98. 2011
    ..This research perspective will address these somewhat contradictory findings and summarize recent research regarding senescence and mTORC1 signaling...