Affiliation: Albert Einstein College of Medicine
- Molecular restoration of archived transcriptional profiles by complementary-template reverse-transcription (CT-RT)Olivier Loudig
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA
Nucleic Acids Res 35:e94. 2007..Our results indicate that CT-RT allows microarray profiling of severely degraded RNA that could not be analyzed by previous methods...
- Effective DNA/RNA co-extraction for analysis of microRNAs, mRNAs, and genomic DNA from formalin-fixed paraffin-embedded specimensAdam Kotorashvili
Department of Epidemiology and Population Health, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York, United States of America
PLoS ONE 7:e34683. 2012..The former limits accurate correlation whilst the latter is impractical when utilizing rare or limited archived specimens...
- Hsa-miR-375 is differentially expressed during breast lobular neoplasia and promotes loss of mammary acinar polarityOrsi Giricz
Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY, USA
J Pathol 226:108-19. 2012..Increased expression of hsa-miR-375 resulted in loss of cellular organization and acquisition of a hyperplastic phenotype. These data suggest that dysregulated miRNA expression contributes to lobular neoplastic progression...
- Illumina whole-genome complementary DNA-mediated annealing, selection, extension and ligation platform: assessing its performance in formalin-fixed, paraffin-embedded samples and identifying invasion pattern-related genes in oral squamous cell carcinomaOlivier Loudig
Department of Pathology, Albert Einstein College of Medicine, Bronx, NY, USA
Hum Pathol 42:1911-22. 2011....
- Low-level expression of miR-375 correlates with poor outcome and metastasis while altering the invasive properties of head and neck squamous cell carcinomasThomas Harris
Department of Pathology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
Am J Pathol 180:917-28. 2012..We conclude that miR-375 represents a potential prognostic marker of poor outcome and metastasis in HNSCC and that it may function by suppressing the tumor's invasive properties...
- Loss of retinal cadherin facilitates mammary tumor progression and metastasisGeorgia Agiostratidou
Department of Pathology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
Cancer Res 69:5030-8. 2009..The data suggest that R-cad is an adhesion molecule of the mammary epithelium, which acts as a critical regulator of the normal phenotype. As a result, R-cad loss contributes to epithelial suppression and metastatic progression...