Mike Lorenz

Summary

Affiliation: Albert Einstein College of Medicine
Country: USA

Publications

  1. ncbi request reprint Imaging sites of N-wasp activity in lamellipodia and invadopodia of carcinoma cells
    Mike Lorenz
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Curr Biol 14:697-703. 2004
  2. pmc Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilin
    Hideki Yamaguchi
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    J Cell Biol 168:441-52. 2005
  3. pmc RhoA/ROCK-mediated switching between Cdc42- and Rac1-dependent protrusion in MTLn3 carcinoma cells
    Mirvat El-Sibai
    Department of Molecular Pharmacology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Exp Cell Res 314:1540-52. 2008
  4. ncbi request reprint ZBP1 enhances cell polarity and reduces chemotaxis
    Kyle Lapidus
    Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY 10461 1975, USA
    J Cell Sci 120:3173-8. 2007
  5. ncbi request reprint Measurement of barbed ends, actin polymerization, and motility in live carcinoma cells after growth factor stimulation
    Mike Lorenz
    Albert Einstein College of Medicine, Department of Anatomy and Structural Biology, Bronx, NY 10461, USA
    Cell Motil Cytoskeleton 57:207-17. 2004
  6. ncbi request reprint Spatial regulation of beta-actin translation by Src-dependent phosphorylation of ZBP1
    Stefan Huttelmaier
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA
    Nature 438:512-5. 2005
  7. pmc The mechanism of CSF-1-induced Wiskott-Aldrich syndrome protein activation in vivo: a role for phosphatidylinositol 3-kinase and Cdc42
    Michael Cammer
    Department of Anatomy, Albert Einstein College of Medicine, Yeshiva University, Bronx, New York 10461, USA
    J Biol Chem 284:23302-11. 2009
  8. ncbi request reprint Distance determination in protein-DNA complexes using fluorescence resonance energy transfer
    Mike Lorenz
    Optical Technology Development, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
    Methods Mol Biol 335:243-55. 2006
  9. ncbi request reprint A peptide motif in Raver1 mediates splicing repression by interaction with the PTB RRM2 domain
    Alexis P Rideau
    Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, CB2 1GA, UK
    Nat Struct Mol Biol 13:839-48. 2006

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Imaging sites of N-wasp activity in lamellipodia and invadopodia of carcinoma cells
    Mike Lorenz
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Curr Biol 14:697-703. 2004
    ..This is the first time that the activity of full-length N-WASP has been visualized in vivo, and this has lead to new insights for N-WASP function...
  2. pmc Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilin
    Hideki Yamaguchi
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    J Cell Biol 168:441-52. 2005
    ..These results indicate that EGF receptor signaling regulates invadopodium formation through the N-WASP-Arp2/3 pathway and cofilin is necessary for the stabilization and maturation of invadopodia...
  3. pmc RhoA/ROCK-mediated switching between Cdc42- and Rac1-dependent protrusion in MTLn3 carcinoma cells
    Mirvat El-Sibai
    Department of Molecular Pharmacology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Exp Cell Res 314:1540-52. 2008
    ..These data describe a novel role for Rho in coordinating signaling by Rac and Cdc42...
  4. ncbi request reprint ZBP1 enhances cell polarity and reduces chemotaxis
    Kyle Lapidus
    Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY 10461 1975, USA
    J Cell Sci 120:3173-8. 2007
    ..We found that ZBP1 expression actually reduced tumor cell motility and chemotaxis, presumably mediating their decreased metastatic potential by reducing their ability to respond to signals necessary for invasion...
  5. ncbi request reprint Measurement of barbed ends, actin polymerization, and motility in live carcinoma cells after growth factor stimulation
    Mike Lorenz
    Albert Einstein College of Medicine, Department of Anatomy and Structural Biology, Bronx, NY 10461, USA
    Cell Motil Cytoskeleton 57:207-17. 2004
    ..This assay has a high potential for applications where rapid changes in the dynamic filament population are to be measured...
  6. ncbi request reprint Spatial regulation of beta-actin translation by Src-dependent phosphorylation of ZBP1
    Stefan Huttelmaier
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA
    Nature 438:512-5. 2005
    ..These sequential events provide both temporal and spatial control over beta-actin mRNA translation, which is important for cell migration and neurite outgrowth...
  7. pmc The mechanism of CSF-1-induced Wiskott-Aldrich syndrome protein activation in vivo: a role for phosphatidylinositol 3-kinase and Cdc42
    Michael Cammer
    Department of Anatomy, Albert Einstein College of Medicine, Yeshiva University, Bronx, New York 10461, USA
    J Biol Chem 284:23302-11. 2009
    ..However, although tyrosine phosphorylation of WASP has been proposed to stimulate WASP activity, we found no evidence to indicate that this occurs in vivo...
  8. ncbi request reprint Distance determination in protein-DNA complexes using fluorescence resonance energy transfer
    Mike Lorenz
    Optical Technology Development, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
    Methods Mol Biol 335:243-55. 2006
    ..Advances in the preparation of dye-labeled nucleic acid molecules and modern techniques like the measurement of FRET in vivo lead to an increased importance of FRET studies in structural and molecular biology...
  9. ncbi request reprint A peptide motif in Raver1 mediates splicing repression by interaction with the PTB RRM2 domain
    Alexis P Rideau
    Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, CB2 1GA, UK
    Nat Struct Mol Biol 13:839-48. 2006
    ..The requirement for the PTB-Raver1 interaction that we have characterized may serve to bring the additional repressor regions of both proteins into a configuration that allows them to synergistically effect exon skipping...