R B Lipton

Summary

Affiliation: Albert Einstein College of Medicine
Country: USA

Publications

  1. doi request reprint Efficacy and tolerability of a new powdered formulation of diclofenac potassium for oral solution for the acute treatment of migraine: results from the International Migraine Pain Assessment Clinical Trial (IMPACT)
    Richard B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Cephalalgia 30:1336-45. 2010
  2. ncbi request reprint The epidemiology of migraine
    Richard B Lipton
    Department of Neurology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA
    Am J Med 118:3S-10S. 2005
  3. ncbi request reprint Headache: triumphs in translational research
    Richard B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA
    Lancet Neurol 4:11-2. 2005
  4. pmc Chronic pain and obesity in elderly people: results from the Einstein aging study
    Lucas H McCarthy
    Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA
    J Am Geriatr Soc 57:115-9. 2009
  5. doi request reprint Barriers to the diagnosis and treatment of migraine: effects of sex, income, and headache features
    Richard B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Headache 53:81-92. 2013
  6. ncbi request reprint Migraine headache disability and health-related quality-of-life: a population-based case-control study from England
    R B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, NY 10461, USA
    Cephalalgia 23:441-50. 2003
  7. ncbi request reprint How treatment priorities influence triptan preferences in clinical practice: perspectives of migraine sufferers, neurologists, and primary care physicians
    R B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Curr Med Res Opin 21:413-24. 2005
  8. ncbi request reprint Assessment of cognitive function of the elderly population: effects of darifenacin
    Richard B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA
    J Urol 173:493-8. 2005
  9. ncbi request reprint Petasites hybridus root (butterbur) is an effective preventive treatment for migraine
    R B Lipton
    Department of Neurology, Albert Einstein College of Medicine, 1165 Morris Park Ave, Rousso Bldg, Rm 332, Bronx, NY 10461, USA
    Neurology 63:2240-4. 2004
  10. ncbi request reprint Patterns of health care utilization for migraine in England and in the United States
    R B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Neurology 60:441-8. 2003

Research Grants

  1. Einstein Aging Study - Supplement
    Richard Lipton; Fiscal Year: 2007

Collaborators

Detail Information

Publications144 found, 100 shown here

  1. doi request reprint Efficacy and tolerability of a new powdered formulation of diclofenac potassium for oral solution for the acute treatment of migraine: results from the International Migraine Pain Assessment Clinical Trial (IMPACT)
    Richard B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Cephalalgia 30:1336-45. 2010
    ..Diclofenac potassium for oral solution has a time to maximum plasma concentration (Tmax) of 15 minutes, suggesting the potential for a rapid onset of therapeutic effects...
  2. ncbi request reprint The epidemiology of migraine
    Richard B Lipton
    Department of Neurology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA
    Am J Med 118:3S-10S. 2005
    ..However, prevalence is high in groups other than these high-risk groups. In a subgroup of patients, migraine may be a progressive disorder...
  3. ncbi request reprint Headache: triumphs in translational research
    Richard B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA
    Lancet Neurol 4:11-2. 2005
  4. pmc Chronic pain and obesity in elderly people: results from the Einstein aging study
    Lucas H McCarthy
    Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA
    J Am Geriatr Soc 57:115-9. 2009
    ..To determine the prevalence of chronic pain in elderly people and its relationship with obesity and associated comorbidities and risk factors...
  5. doi request reprint Barriers to the diagnosis and treatment of migraine: effects of sex, income, and headache features
    Richard B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Headache 53:81-92. 2013
    ..We assessed barriers at 3 levels: medical consultation, diagnosis, and acute pharmacologic therapy use and assessed the contribution of socioeconomic, demographic, and headache-specific variables to these barriers...
  6. ncbi request reprint Migraine headache disability and health-related quality-of-life: a population-based case-control study from England
    R B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, NY 10461, USA
    Cephalalgia 23:441-50. 2003
    ..Specifically, individuals classified with moderate to severe work-related disability had lower HRQoL scores than those classified with low disability...
  7. ncbi request reprint How treatment priorities influence triptan preferences in clinical practice: perspectives of migraine sufferers, neurologists, and primary care physicians
    R B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Curr Med Res Opin 21:413-24. 2005
    ..In treating migraine sufferers, physicians can choose from among seven triptans with different attributes...
  8. ncbi request reprint Assessment of cognitive function of the elderly population: effects of darifenacin
    Richard B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA
    J Urol 173:493-8. 2005
    ..In this study we evaluated the effect of darifenacin, an M3 selective antagonist, on cognitive function in elderly volunteers without clinical dementia...
  9. ncbi request reprint Petasites hybridus root (butterbur) is an effective preventive treatment for migraine
    R B Lipton
    Department of Neurology, Albert Einstein College of Medicine, 1165 Morris Park Ave, Rousso Bldg, Rm 332, Bronx, NY 10461, USA
    Neurology 63:2240-4. 2004
    ..To evaluate the clinical efficacy of a standardized special root extract from the plant Petasites hybridus as a preventive therapy for migraine...
  10. ncbi request reprint Patterns of health care utilization for migraine in England and in the United States
    R B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Neurology 60:441-8. 2003
    ..To assess patterns of medical consultation, diagnosis, and medication use in representative samples of adults with migraine in England and the United States...
  11. ncbi request reprint Why headache treatment fails
    R B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY10461, USA
    Neurology 60:1064-70. 2003
    ..Persistence in treating these patients can be very rewarding. The authors provide a checklist intended to facilitate the management of refractory patients...
  12. ncbi request reprint The family impact of migraine: population-based studies in the USA and UK
    R B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Cephalalgia 23:429-40. 2003
    ..02), with their level or responsibilities and duties (P = 0.02), and with their ability to perform (P = 0.001). Results from this study show that the impact of migraine extends to household partners and other family members...
  13. doi request reprint Single-pulse transcranial magnetic stimulation for acute treatment of migraine with aura: a randomised, double-blind, parallel-group, sham-controlled trial
    Richard B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Lancet Neurol 9:373-80. 2010
    ..We aimed to assess the efficacy and safety of a new portable sTMS device for acute treatment of migraine with aura...
  14. ncbi request reprint A self-administered screener for migraine in primary care: The ID Migraine validation study
    R B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Neurology 61:375-82. 2003
    ....
  15. ncbi request reprint Screening for dementia by telephone using the memory impairment screen
    Richard B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    J Am Geriatr Soc 51:1382-90. 2003
    ..To develop and assess telephone-based screening tests for dementia, especially Alzheimer's disease (AD)...
  16. ncbi request reprint Acetaminophen in the treatment of headaches associated with dipyridamole-aspirin combination
    R B Lipton
    Department of Neurology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Neurology 63:1099-101. 2004
    ..The headaches were self-limited (69.4% placebo efficacy in 2 hours) and the incidence markedly declined over time. Acetaminophen was no more effective than placebo in the acute and preemptive treatment of these headaches...
  17. ncbi request reprint Classification of primary headaches
    R B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461 1926, USA
    Neurology 63:427-35. 2004
    ..They conclude by presenting an approach to headache diagnosis based upon these criteria...
  18. ncbi request reprint Migraine practice patterns among neurologists
    R B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Neurology 62:1926-31. 2004
    ..To assess the attitudes, knowledge, and practice patterns of US neurologists regarding migraine management relative to the US Headache Consortium Guidelines (the Guidelines)...
  19. ncbi request reprint CGRP antagonists in the acute treatment of migraine
    Richard B Lipton
    Department of Neurology, Epidemiology and Population Health, Albert Einstein College of Medicine, New York, NY, USA
    Lancet Neurol 3:332. 2004
  20. ncbi request reprint Migraine: primary care challenges in diagnosis and treatment. Introduction
    Richard B Lipton
    Department of Neurology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA
    Am J Med 118:1S-2S. 2005
  21. ncbi request reprint Double-blind clinical trials of oral triptans vs other classes of acute migraine medication - a review
    R B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Cephalalgia 24:321-32. 2004
    ....
  22. doi request reprint Validity and reliability of the Migraine-Treatment Optimization Questionnaire
    R B Lipton
    Department of Neurology, Albert Einstein College of Medicine, New York, NY 10461, USA
    Cephalalgia 29:751-9. 2009
    ..66, and it also correlated well with the three questionnaires (r = 0.33-0.41). The utility of the M-TOQ for assessing treatment benefit in research (M-TOQ-15) and primary care (M-TOQ-5) should be further validated...
  23. doi request reprint Tracing transformation: chronic migraine classification, progression, and epidemiology
    Richard B Lipton
    Department of Neurology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Neurology 72:S3-7. 2009
    ..Emerging data on the longitudinal risk of CM suggest that, in a population at risk, CM may be a preventable disorder...
  24. pmc In-office discussions of migraine: results from the American Migraine Communication Study
    Richard B Lipton
    Department of Neurology, Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    J Gen Intern Med 23:1145-51. 2008
    ..However, no studies outline how migraine is actually discussed during clinical encounters...
  25. pmc Cutaneous allodynia in the migraine population
    Richard B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Ann Neurol 63:148-58. 2008
    ..To develop and validate a questionnaire for assessing cutaneous allodynia (CA), and to estimate the prevalence and severity of CA in the migraine population...
  26. ncbi request reprint Migraine prevalence, disease burden, and the need for preventive therapy
    R B Lipton
    Department of Neurology, The Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Neurology 68:343-9. 2007
    ....
  27. ncbi request reprint How useful is the HIT-6 for measuring headache-related disability?
    Richard B Lipton
    Neurology, Albert Einstein College of Medicine, NY 10641, USA
    Nat Clin Pract Neurol 2:70-1. 2006
  28. ncbi request reprint Clinical trials of acute treatments for migraine including multiple attack studies of pain, disability, and health-related quality of life
    R B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Neurology 65:S50-8. 2005
    ..We consider clinical trials strategies designed to address the more complex clinical and policy requirements for meeting the needs of those with migraine...
  29. doi request reprint Chronic migraine, classification, differential diagnosis, and epidemiology
    Richard B Lipton
    Albert Einstein College of Medicine Neurology, Bronx, NY 10461, USA
    Headache 51:77-83. 2011
    ..These findings highlight the paramount importance of clinical vigilance, accurate diagnosis, and appropriate, effective management - including treatment or referrals - to improve patient outcomes...
  30. ncbi request reprint Migraine in adolescents: association with socioeconomic status and family history
    M E Bigal
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Neurology 69:16-25. 2007
    ..The influence of socioeconomic status on the prevalence of migraine is unknown in adolescents. Accordingly, we investigated the prevalence of migraine in a large sample of adolescents by sociodemographic features...
  31. ncbi request reprint Chronic migraine is an earlier stage of transformed migraine in adults
    M E Bigal
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA
    Neurology 65:1556-61. 2005
    ..They are often classified as transformed migraine (TM), a disorder not addressed in the International Headache Society classification...
  32. pmc Cognitive activities delay onset of memory decline in persons who develop dementia
    C B Hall
    Department of Epidemiology and Population Health, and Department of Neurology, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY 10461, USA
    Neurology 73:356-61. 2009
    ..Early life education and participation in cognitively stimulating leisure activities later in life are 2 factors thought to reflect cognitive reserve, which may delay the onset of the memory decline in the preclinical stages of dementia...
  33. ncbi request reprint Effect of rizatriptan and other triptans on the nausea symptom of migraine: a post hoc analysis
    R B Lipton
    Albert Einstein College of Medicine, Bronx, NY, USA
    Headache 41:754-63. 2001
    ..Rates of emergent nausea in patients who were free of it at baseline were low, and no consistent differences were observed between active treatments...
  34. ncbi request reprint Estimation of bivariate measurements having different change points, with application to cognitive ageing
    C B Hall
    Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY 10461, U S A
    Stat Med 20:3695-714. 2001
    ....
  35. pmc Hippocampal correlates of pain in healthy elderly adults: a pilot study
    M E Zimmerman
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Neurology 73:1567-70. 2009
    ..The goal of this pilot study was to examine MRI- and magnetic resonance spectroscopy (MRS)-derived hippocampal correlates of pain in older adults...
  36. ncbi request reprint Prevalence and impact of migraine and probable migraine in a health plan
    N V Patel
    AdvancePCS, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Neurology 63:1432-8. 2004
    ..A large number of headache sufferers with features of migraine fail to meet criteria for strict migraine (SM; migraine with or without aura) but do meet criteria for probable migraine (PM)...
  37. ncbi request reprint Incidence of epilepsy in a racially diverse, community-dwelling, elderly cohort: results from the Einstein aging study
    S A Hussain
    Department of Neurology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA
    Epilepsy Res 71:195-205. 2006
    ..To determine age-specific incidence and cumulative incidence of epilepsy in a well-defined cohort of elderly people, and to examine how rates of epilepsy are modified by sex, race, stroke, dementia, head injury, and depression...
  38. ncbi request reprint Education delays accelerated decline on a memory test in persons who develop dementia
    C B Hall
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10462, USA
    Neurology 69:1657-64. 2007
    ..To test the cognitive reserve hypothesis by examining the effect of education on memory decline during the preclinical course of dementia...
  39. ncbi request reprint Dementia incidence may increase more slowly after age 90: results from the Bronx Aging Study
    C B Hall
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA
    Neurology 65:882-6. 2005
    ..Dementia incidence increases dramatically from age 65 to age 85, with many studies reporting a doubling every 5 years. The incidence beyond age 85 is not established...
  40. ncbi request reprint Migraine days decline with duration of illness in adolescents with transformed migraine
    M E Bigal
    Department of Neurology, Albert Einstein College of Medicine, New York, NY, USA
    Cephalalgia 25:482-7. 2005
    ..These findings suggest that early in the process of transformation, migraine is more frequent, and that as CDH evolves, fewer typical attacks of IHS migraine occur...
  41. doi request reprint Sociodemographic and comorbidity profiles of chronic migraine and episodic migraine sufferers
    D C Buse
    Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA
    J Neurol Neurosurg Psychiatry 81:428-32. 2010
    ..To characterise and compare the sociodemographic profiles and the frequency of common comorbidities for adults with chronic migraine (CM) and episodic migraine (EM) in a large population-based sample...
  42. ncbi request reprint Efficacy and safety of acetaminophen, aspirin, and caffeine in alleviating migraine headache pain: three double-blind, randomized, placebo-controlled trials
    R B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Montefiore Headache Unit, Bronx, NY 10467, USA
    Arch Neurol 55:210-7. 1998
    ..To assess the effectiveness of the nonprescription combination of acetaminophen, aspirin, and caffeine in alleviating migraine headache pain...
  43. ncbi request reprint Memory and mental status correlates of modified Braak staging
    E Grober
    Department of Neurology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY, USA
    Neurobiol Aging 20:573-9. 1999
    ..We conclude that Braak staging provides a useful summary of Alzheimer's disease neuropathology, which is associated with both memory and mental status performance...
  44. ncbi request reprint High risk neurological gait syndrome and vascular dementia
    J Verghese
    Einstein Aging Study, Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, U S A
    J Neural Transm 114:1249-52. 2007
    ..5, 95% CI 5.5-28.4) or either (HR 5.9, 95% CI 3.6-9.7) had higher risk of VD over five years. Diagnosing HRNG is a clinically relevant approach to identifying older adults at high risk of VD over short intervals...
  45. ncbi request reprint Migraine in the United States: epidemiology and patterns of health care use
    R B Lipton
    Department of Neurology, Albert Einstein College of Medicine, and Headache Unit, Montefiore Medical College, Bronx, NY, USA
    Neurology 58:885-94. 2002
    ..To determine the prevalence and distribution of migraine in the United States as well as current patterns of health care use...
  46. ncbi request reprint The effects of preclinical dementia on estimates of normal cognitive functioning in aging
    M Sliwinski
    Saul R Korey Department of Neurology, Albert Einstein College of Medicine, USA
    J Gerontol B Psychol Sci Soc Sci 51:P217-25. 1996
    ..Methods are discussed for selecting robust elderly samples that are relatively free of contamination by preclinical dementia...
  47. ncbi request reprint 2000 Wolfe Award. Sumatriptan for the range of headaches in migraine sufferers: results of the Spectrum Study
    R B Lipton
    Albert Einstein Medical College and Montefiore Headache Unit, New York, NY, USA
    Headache 40:783-91. 2000
    ..0005) compared with placebo. CONCLUSION: Sumatriptan, 50-mg tablets, are effective for the full spectrum of headaches experienced by patients with disabling migraine due to a sumatriptan-responsive mechanism...
  48. ncbi request reprint Memory impairment on free and cued selective reminding predicts dementia
    E Grober
    Department of Neurology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY 10461, USA
    Neurology 54:827-32. 2000
    ..To estimate the relative rates of dementia in initially nondemented subjects with and without memory impairment defined by baseline free recall from the Free and Cued Selective Reminding (FCSR) test...
  49. ncbi request reprint Demographic influences on free and cued selective reminding performance in older persons
    E Grober
    Saul Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, NY 10461, USA
    J Clin Exp Neuropsychol 20:221-6. 1998
    ..Although age, education, and gender influenced FCSR performance, race did not. The study suggests that memory performance is not influenced by race and that race-adjustment may not be necessary in the norming of memory tests...
  50. pmc Gender differences in the IL6 -174G>C and ESR2 1730G>A polymorphisms and the risk of Parkinson's disease
    M San Luciano
    Department of Neurology, Beth Israel Medical Center, 10 Union Square East Suite 5K, New York, NY 10003, United States
    Neurosci Lett 506:312-6. 2012
    ..Larger studies in diverse populations, including analysis of surrounding regions are recommended...
  51. pmc Hippocampal neurochemistry, neuromorphometry, and verbal memory in nondemented older adults
    M E Zimmerman
    Albert Einstein College of Medicine, Saul R Korey Department of Neurology, 1165 Morris Park Ave, Room 343, Bronx, NY 10461, USA
    Neurology 70:1594-600. 2008
    ..The objective of this study was to test the hypothesis that a measure of hippocampal neuronal metabolism was associated with verbal memory in nondemented older adults after controlling for hippocampal volume...
  52. pmc Prevalence and characteristics of allodynia in headache sufferers: a population study
    M E Bigal
    Departments of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA
    Neurology 70:1525-33. 2008
    ..The authors estimated the prevalence and severity of cutaneous allodynia (CA) in individuals with primary headaches from the general population...
  53. doi request reprint OnabotulinumtoxinA improves quality of life and reduces impact of chronic migraine
    R B Lipton
    Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Neurology 77:1465-72. 2011
    ..To assess the effects of treatment with onabotulinumtoxinA (Botox, Allergan, Inc., Irvine, CA) on health-related quality of life (HRQoL) and headache impact in adults with chronic migraine (CM)...
  54. ncbi request reprint A genotype of exceptional longevity is associated with preservation of cognitive function
    N Barzilai
    Institute for Aging Research, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Neurology 67:2170-5. 2006
    ..To test whether cholesterol ester transfer protein (CETP) genotype (VV homozygosity for I405V) is associated with preservation of cognitive function in addition to its association with exceptional longevity...
  55. ncbi request reprint Migraine's impact today. Burden of illness, patterns of care
    R B Lipton
    Albert Einstein College of Medicine of Yeshiva University, Bronx, New York, USA
    Postgrad Med 109:38-40, 43-5. 2001
    ..In this article, Drs Lipton, Stewart, Reed, and Diamond consider the scope and distribution of the migraine problem and the current patterns of care in the United States...
  56. ncbi request reprint Field testing alternative criteria for chronic migraine
    M E Bigal
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA
    Cephalalgia 26:477-82. 2006
    ..Consistently, criteria for CM and CM+ should be revised to require at least 8 days of migraine or probable migraine per month, in individuals with 15 or more days of headache per month...
  57. ncbi request reprint Headache prevention outcome and body mass index
    M E Bigal
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA
    Cephalalgia 26:445-50. 2006
    ..Contrary to what we hypothesized, obesity at baseline does not seem to be related to follow-up refractoriness to preventive treatment...
  58. pmc Memory impairment, executive dysfunction, and intellectual decline in preclinical Alzheimer's disease
    Ellen Grober
    Department of Neurology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York 10467, USA
    J Int Neuropsychol Soc 14:266-78. 2008
    ..It also supports the view that VIQ as estimated by the AMNART does not decline during the preclinical onset of AD...
  59. pmc Exceptional parental longevity associated with lower risk of Alzheimer's disease and memory decline
    Richard B Lipton
    Einstein Aging Study, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    J Am Geriatr Soc 58:1043-9. 2010
    ..To determine whether offspring of parents with exceptional longevity (OPEL) have a lower rate of dementia than offspring of parents with usual survival (OPUS)...
  60. ncbi request reprint Cognitive performance in surgically menopausal women on estrogen
    J Verghese
    Einstein Aging Study, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Neurology 55:872-4. 2000
    ..These results suggest that ERT initiated soon after surgical menopause can have long-term neuroprotective effects in cognitively intact women...
  61. ncbi request reprint Patterns of medical diagnosis and treatment of migraine and probable migraine in a health plan
    M E Bigal
    Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, NY, USA
    Cephalalgia 26:43-9. 2006
    ..Educational strategies should focus on physician education addressing diagnosing the full spectrum of migraine and physician management of migraine with specific migraine therapy in appropriate patients...
  62. ncbi request reprint Migraine, quality of life, and depression: a population-based case-control study
    R B Lipton
    Departments of Neurology, Epidemiology, and Social Medicine Dr Lipton, Albert Einstein College of Medicine, Bronx, NY, USA
    Neurology 55:629-35. 2000
    ..This study reports on the influence of migraine and comorbid depression on health-related quality of life (HRQoL) in a population-based sample of subjects with migraine and nonmigraine controls...
  63. pmc Clinical and prognostic subforms of new daily-persistent headache
    M S Robbins
    The Montefiore Headache Center, 1575 Blondell Avenue, Suite 225, Bronx, NY 10461, USA
    Neurology 74:1358-64. 2010
    ..When migraine features are present, classification is problematic...
  64. ncbi request reprint An update on the epidemiology of migraine
    R B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY
    Headache 34:319-28. 1994
    ..In this article, we review some of the methodological challenges in studying migraine epidemiology, report recent results from studies using IHS criteria, and suggest directions for future research...
  65. ncbi request reprint Primary chronic daily headache and its subtypes in adolescents and adults
    M E Bigal
    Department of Neurology, Albert Einstein College of Medicine, 1165 Morris Park Avenue, Bronx, NY 10461, USA
    Neurology 63:843-7. 2004
    ..To determine the relative frequency of chronic daily headache (CDH) subtypes in adolescents and to compare the distribution of CDH subtypes in adolescents and adults of various ages...
  66. ncbi request reprint Transformed migraine and medication overuse in a tertiary headache centre--clinical characteristics and treatment outcomes
    M E Bigal
    Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA
    Cephalalgia 24:483-90. 2004
    ..001). More rigorous prescribing guidelines for patients with frequent headaches are urgently needed. Successful detoxification is necessary to ensure improvement in the headache status when treating patients who overuse acute medications...
  67. pmc Leisure activities and the risk of amnestic mild cognitive impairment in the elderly
    J Verghese
    Department of Neurology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Neurology 66:821-7. 2006
    ..To study the influence of leisure activity participation on risk of development of amnestic mild cognitive impairment (aMCI)...
  68. ncbi request reprint Randomized trial of IV dexamethasone for acute migraine in the emergency department
    B W Friedman
    Department of Emergency Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, 111 East 210th Street, Bronx, NY 10467, USA
    Neurology 69:2038-44. 2007
    ..It is not yet clear if corticosteroids are useful for the treatment of migraine. We determined the efficacy of 10 mg of IV dexamethasone as adjuvant therapy for patients presenting to an emergency department (ED) with acute migraine...
  69. doi request reprint Coexisting trigeminal autonomic cephalalgias and hemicrania continua
    Matthew S Robbins
    Montefiore Headache Center, Saul R Korey Department of Neurology, Bronx, NY 10461, USA
    Headache 50:489-96. 2010
    ..We then review previous reports of patients with coexisting TACs and HC and discuss the relationship between these families of primary headache disorders...
  70. ncbi request reprint Ten lessons on the epidemiology of migraine
    Richard B Lipton
    Montefiore Headache Unit, Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Headache 47:S2-9. 2007
    ....
  71. ncbi request reprint Head or neck injury increases the risk of chronic daily headache: a population-based study
    James R Couch
    Department of Neurology, University of Oklahoma Medical School, Oklahoma City, OK 73104, USA
    Neurology 69:1169-77. 2007
    ..To evaluate the extent to which head and neck injury (HANI) contributes to chronic daily headache (CDH)...
  72. doi request reprint Predictors of migraine headache recurrence: a pooled analysis from the eletriptan database
    David W Dodick
    Department of Neurology, Mayo Clinic, Scottsdale, AZ 85259, USA
    Headache 48:184-93. 2008
    ....
  73. ncbi request reprint The effect of dementia risk factors on comparative and diagnostic selective reminding norms
    M Sliwinski
    Saul R Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    J Int Neuropsychol Soc 3:317-26. 1997
    ..It is concluded that statistically removing the contribution of dementia risk factors from memory test scores can severely decrease discriminative validity for detecting dementia in the elderly...
  74. doi request reprint Consistency of response to sumatriptan/naproxen sodium in a placebo-controlled, crossover study
    R B Lipton
    Albert Einstein College of Medicine and the Montefiore Headache Center, Bronx, New York, NY 10461, USA
    Cephalalgia 29:826-36. 2009
    ..7% of patients in Study 1 and 32.6% of patients in Study 2. The incidences of any adverse event and of specific adverse events were low and generally similar between S/NS and placebo...
  75. pmc Differential effects of COMT on gait and executive control in aging
    R Holtzer
    Department of Neurology, Albert Einstein College of Medicine, Yeshiva University, Bronx, NY 10461, United States
    Neurobiol Aging 31:523-31. 2010
    ..These findings suggest a differential effect in relating the Val(158)Met polymorphism to gait and to cognitive function while supporting the previously described sexual dimorphism in the phenotypic expressions of COMT...
  76. pmc Identifying seizure clusters in patients with epilepsy
    S R Haut
    Comprehensive Epilepsy Management Center, Montefiore Medical Center, The Albert Einstein College of Medicine, Bronx, NY, USA
    Neurology 65:1313-5. 2005
    ..Utilizing the clinical definition of clustering should identify all seizure clusterers, and false positives can be determined with diary data...
  77. ncbi request reprint The relative frequency of "dementia of unknown etiology" increases with age and is nearly 50% in nonagenarians
    H A Crystal
    Einstein Aging Study, Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Arch Neurol 57:713-9. 2000
    ..Whether these unclassified patients have vascular dementia or some other form of dementia is not known...
  78. ncbi request reprint Low blood pressure and the risk of dementia in very old individuals
    J Verghese
    Einstein Aging Study, Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Neurology 61:1667-72. 2003
    ..The role of blood pressure (BP) as a risk factor for dementia is complex and may be age dependent. In very old individuals, low BP might increase risk for dementia, perhaps by reducing cerebral perfusion pressure...
  79. ncbi request reprint Epilepsy and migraine
    M E Bigal
    Department of Neurology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Epilepsy Behav 4:S13-24. 2003
    ..We summarize the epidemiologic evidence that migraine and epilepsy are associated and discuss specific interrelationships between migraine and epilepsy...
  80. ncbi request reprint Naratriptan as short-term prophylaxis of menstrually associated migraine: a randomized, double-blind, placebo-controlled study
    L Newman
    St. Luke's-Roosevelt Hospital Center, Headache Institute, New York, NY 10019, USA
    Headache 41:248-56. 2001
    ..5 mg, was not statistically superior to placebo for any measure. CONCLUSIONS: Naratriptan, 1 mg, with tolerability similar to placebo, is an effective, short-term, prophylactic treatment for menstrually associated migraine...
  81. ncbi request reprint A new screening tool for cervical dystonia
    R Saunders-Pullman
    Department of Neurology, Beth Israel Medical Center, 10 Union Square E, Suite 5J, PACC, New York, NY 10003, USA
    Neurology 64:2046-9. 2005
    ..As a low-cost highly sensitive screening tool is needed to improve case detection for genetic and epidemiologic studies, the authors developed the Beth Israel Dystonia Screen (BIDS), a computer-assisted telephone interview...
  82. pmc Quantitative gait markers and incident fall risk in older adults
    Joe Verghese
    MBBS, Einstein Aging Study, Albert Einstein College of Medicine, Yeshiva University, 1165 Morris Park Avenue, Room 338, Bronx, NY 10461, USA
    J Gerontol A Biol Sci Med Sci 64:896-901. 2009
    ..Identifying quantitative gait markers of falls in older adults may improve diagnostic assessments and suggest novel intervention targets...
  83. ncbi request reprint Leisure activities and the risk of dementia in the elderly
    Joe Verghese
    Einstein Aging Study, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    N Engl J Med 348:2508-16. 2003
    ..It is unclear whether increased participation in leisure activities lowers the risk of dementia or participation in leisure activities declines during the preclinical phase of dementia...
  84. pmc Gait dysfunction in mild cognitive impairment syndromes
    Joe Verghese
    Department of Neurology, Einstein Aging Study, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    J Am Geriatr Soc 56:1244-51. 2008
    ..To conduct a systematic clinical and quantitative assessment of gait in older adults with mild cognitive impairment (MCI) syndromes...
  85. doi request reprint Predicting seizures: a behavioral approach
    Sheryl R Haut
    Department of Neurology, Montefiore Medical Center, Albert Einstein College of Medicine, 111 East 210th Street, Bronx, New York, NY 10467, USA
    Neurol Clin 27:925-40. 2009
    ..More prospective studies are needed; challenges certainly exist, but as the studies discussed here demonstrate, the field is rich with promise for improving the lives of patients with epilepsy...
  86. doi request reprint Transcranial magnetic simulation in the treatment of migraine
    Richard B Lipton
    Department of Neurology, Montefiore Headache Center, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Neurotherapeutics 7:204-12. 2010
    ..A small body of evidence suggests that rTMS may have a role, but further studies are needed. In this review, we summarize the data on TMS as a treatment of migraine, and we suggest directions for future research...
  87. doi request reprint The prognosis of migraine
    Marcelo E Bigal
    Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA
    Curr Opin Neurol 21:301-8. 2008
    ..In many, migraine may have a very benign (complete remission) or relatively benign (partial remission) prognosis. In some, migraine persists and in others, it progresses...
  88. ncbi request reprint Abnormality of gait as a predictor of non-Alzheimer's dementia
    Joe Verghese
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    N Engl J Med 347:1761-8. 2002
    ..Neurologic abnormalities affecting gait occur early in several types of non-Alzheimer's dementias, but their value in predicting the development of dementia is uncertain...
  89. pmc Robust norms for selected neuropsychological tests in older adults
    Roee Holtzer
    Department of Neurology, Albert Einstein College of Medicine, Yeshiva University, Bronx, NY 10461, USA
    Arch Clin Neuropsychol 23:531-41. 2008
    ..We suggest that longitudinal robust norms may help mitigate the limitations inherent in cross-sectional normative samples...
  90. pmc Neurological gait abnormalities and risk of falls in older adults
    Joe Verghese
    Department of Neurology, Albert Einstein College of Medicine, Yeshiva University, 1165 Morris Park Avenue, Room 301, Bronx, NY 10461, USA
    J Neurol 257:392-8. 2010
    ..Neurological gaits and subtypes are independent predictors of falls in older adults. Neurological gait assessments will help clinicians identify and institute preventive measures in older adults at high risk for falls...
  91. ncbi request reprint Detecting dementia with the Hopkins Verbal Learning Test and the Mini-Mental State Examination
    Gail Kuslansky
    Einstein Aging Study, Department of Neurology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York City, NY 10461, USA
    Arch Clin Neuropsychol 19:89-104. 2004
    ..The modest sensitivity of either the HVLT or the MMSE alone suggests that further neuropsychological evaluation is required to confirm dementia diagnosis...
  92. pmc Leisure activities and risk of vascular cognitive impairment in older adults
    Joe Verghese
    Department of Neurology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    J Geriatr Psychiatry Neurol 22:110-8. 2009
    ..Prospective studies and clinical trials are needed to define the causal role of cognitive leisure activities in influencing vascular risk for cognitive decline...
  93. ncbi request reprint The medical management of migraine
    Marcelo E Bigal
    Department of Neurology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Am J Ther 11:130-40. 2004
    ..The clinicians have in their armamentariums an ever-expanding variety of medications. With experience, clinicians can match individual patient needs with the specific characteristics of a drug to optimize therapeutic benefit...
  94. ncbi request reprint The epidemiology and impact of migraine
    Marcelo E Bigal
    Department of Neurology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Curr Neurol Neurosci Rep 4:98-104. 2004
    ..Probable migraine is a prevalent form of migraine, and like migraine with and without aura it produces decrements in health-related quality of life and increments in disability relative to control subjects...
  95. pmc Seizures in the elderly: impact on mental status, mood, and sleep
    Sheryl R Haut
    Comprehensive Epilepsy Management Center, Montefiore Medical Center and the Albert Einstein College of Medicine, Bronx, NY 10467 2490, USA
    Epilepsy Behav 14:540-4. 2009
    ..Mental status impairment was not related to antiepileptic medication or mood disturbance. Further investigation will explore these associations prospectively...
  96. pmc Assessing and managing all aspects of migraine: migraine attacks, migraine-related functional impairment, common comorbidities, and quality of life
    Dawn C Buse
    Department of Neurology, Montefiore Headache Center, Bronx, NY 10461, USA
    Mayo Clin Proc 84:422-35. 2009
    ..Both pharmacotherapy (acute and preventive treatment strategies) and nonpharmacological therapies play important roles in the management of migraine...
  97. doi request reprint Early follow-up data from seizure diaries can be used to predict subsequent seizures in same cohort by borrowing strength across participants
    Charles B Hall
    Department of Epidemiology and Population Health, Bronx, NY 10471, USA
    Epilepsy Behav 14:472-5. 2009
    ..The possibility of clinically relevant prediction should be examined through electronic data capture and more specific and more frequent sampling, and with patient training to improve prediction...
  98. pmc Egocentric and exocentric navigation skills in older adults
    Amy E Sanders
    Albert Einstein College of Medicine, Bronx, NY 10461, USA
    J Gerontol A Biol Sci Med Sci 63:1356-63. 2008
    ..Our objective was to develop tests of navigation and study their cognitive correlates in nondemented older adults...
  99. doi request reprint The epidemiology of primary headache disorders
    Matthew S Robbins
    The Montefiore Headache Center, Saul R Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA
    Semin Neurol 30:107-19. 2010
    ..The incidence, prevalence, burden, and comorbidities of these disorders are discussed, and the risk factors for progression from episodic to chronic daily headache are also reviewed...
  100. ncbi request reprint Migraine at all ages
    Marcelo E Bigal
    Albert Einstein College of Medicine, Department of Neurology, 1165 Morris Park Avenue, Bronx, NY 10451, USA
    Curr Pain Headache Rep 10:207-13. 2006
    ..Clarifying the influence of age on migraine is of importance for clinical diagnosis and treatment. It also may contain clues to evolving disease biology...
  101. ncbi request reprint Obesity and chronic daily headache
    Marcelo E Bigal
    Department of Neurology, Albert Einstein College of Medicine, 1165 Morris Park Avenue, Bronx, NY 10461, USA
    Curr Pain Headache Rep 12:56-61. 2008
    ..We then review the potential pathophysiologic mechanisms to support this relationship. We close by briefly discussing clinical interventions related to obesity and migraine...

Research Grants2

  1. Einstein Aging Study - Supplement
    Richard Lipton; Fiscal Year: 2007
    ..On a long-term basis the repository will allow us to conduct genome scans and to relate any number of genes to the wealth of clinical and biological outcome data obtained in the EAS. ..