R Holtzer

Summary

Affiliation: Albert Einstein College of Medicine
Country: USA

Publications

  1. pmc Age effects on load-dependent brain activations in working memory for novel material
    Roee Holtzer
    Ferkauf Graduate School of Psychology, Yeshiva University, NY, USA
    Brain Res 1249:148-61. 2009
  2. pmc The relationship between specific cognitive functions and falls in aging
    Roee Holtzer
    Ferkauf Graduate School of Psychology, Albert Einstein College of Medicine, Yeshiva University, NY 10461, USA
    Neuropsychology 21:540-8. 2007
  3. ncbi request reprint Cognitive processes related to gait velocity: results from the Einstein Aging Study
    Roee Holtzer
    Yeshiva University, Bronx, NY 10461, USA
    Neuropsychology 20:215-23. 2006
  4. pmc Extending the administration time of the letter fluency test increases sensitivity to cognitive status in aging
    Roee Holtzer
    Department of Neurology, Albert Einstein College of Medicine, Yeshiva University, Bronx, New York 10461, USA
    Exp Aging Res 35:317-26. 2009
  5. pmc Differential effects of COMT on gait and executive control in aging
    R Holtzer
    Department of Neurology, Albert Einstein College of Medicine, Yeshiva University, Bronx, NY 10461, United States
    Neurobiol Aging 31:523-31. 2010
  6. pmc Robust norms for selected neuropsychological tests in older adults
    Roee Holtzer
    Department of Neurology, Albert Einstein College of Medicine, Yeshiva University, Bronx, NY 10461, USA
    Arch Clin Neuropsychol 23:531-41. 2008
  7. pmc Within-person across-neuropsychological test variability and incident dementia
    Roee Holtzer
    Department of Neurology, Albert Einstein College of Medicine, Yeshiva University, Bronx, NY 10461, USA
    JAMA 300:823-30. 2008
  8. pmc The relationship between subjective reports of fatigue and executive control in multiple sclerosis
    R Holtzer
    Department of Neurology, Albert Einstein College of Medicine, Yeshiva University, Bronx, New York 10461, USA
    J Neurol Sci 281:46-50. 2009
  9. ncbi request reprint Predicting age-related dual-task effects with individual differences on neuropsychological tests
    Roee Holtzer
    Cognitive Neuroscience Division of the Taub Institute, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Neuropsychology 19:18-27. 2005
  10. pmc Egocentric and exocentric navigation skills in older adults
    Amy E Sanders
    Albert Einstein College of Medicine, Bronx, NY 10461, USA
    J Gerontol A Biol Sci Med Sci 63:1356-63. 2008

Detail Information

Publications26

  1. pmc Age effects on load-dependent brain activations in working memory for novel material
    Roee Holtzer
    Ferkauf Graduate School of Psychology, Yeshiva University, NY, USA
    Brain Res 1249:148-61. 2009
    ..Delineating how these theories work in concert can increase knowledge of age-related effects on working memory...
  2. pmc The relationship between specific cognitive functions and falls in aging
    Roee Holtzer
    Ferkauf Graduate School of Psychology, Albert Einstein College of Medicine, Yeshiva University, NY 10461, USA
    Neuropsychology 21:540-8. 2007
    ..Memory was not associated with either single or recurrent falls. These findings are relevant to risk assessment and prevention of falls and point to possible shared neural substrates of cognitive and motor function...
  3. ncbi request reprint Cognitive processes related to gait velocity: results from the Einstein Aging Study
    Roee Holtzer
    Yeshiva University, Bronx, NY 10461, USA
    Neuropsychology 20:215-23. 2006
    ..These findings suggest that gait velocity and cognitive function may have both shared and independent brain substrates. Future studies should explore gait velocity and cognitive function as predictors of dementia and falls...
  4. pmc Extending the administration time of the letter fluency test increases sensitivity to cognitive status in aging
    Roee Holtzer
    Department of Neurology, Albert Einstein College of Medicine, Yeshiva University, Bronx, New York 10461, USA
    Exp Aging Res 35:317-26. 2009
    ..Finally, discriminant function analyses revealed that extending the letter fluency trials to 2 minutes increased discrimination between the control and cognitive impairment groups...
  5. pmc Differential effects of COMT on gait and executive control in aging
    R Holtzer
    Department of Neurology, Albert Einstein College of Medicine, Yeshiva University, Bronx, NY 10461, United States
    Neurobiol Aging 31:523-31. 2010
    ..These findings suggest a differential effect in relating the Val(158)Met polymorphism to gait and to cognitive function while supporting the previously described sexual dimorphism in the phenotypic expressions of COMT...
  6. pmc Robust norms for selected neuropsychological tests in older adults
    Roee Holtzer
    Department of Neurology, Albert Einstein College of Medicine, Yeshiva University, Bronx, NY 10461, USA
    Arch Clin Neuropsychol 23:531-41. 2008
    ..We suggest that longitudinal robust norms may help mitigate the limitations inherent in cross-sectional normative samples...
  7. pmc Within-person across-neuropsychological test variability and incident dementia
    Roee Holtzer
    Department of Neurology, Albert Einstein College of Medicine, Yeshiva University, Bronx, NY 10461, USA
    JAMA 300:823-30. 2008
    ..Neuropsychological tests are used to predict and diagnose dementia. However, to our knowledge, no studies to date have examined whether within-person across-neuropsychological test variability predicts dementia...
  8. pmc The relationship between subjective reports of fatigue and executive control in multiple sclerosis
    R Holtzer
    Department of Neurology, Albert Einstein College of Medicine, Yeshiva University, Bronx, New York 10461, USA
    J Neurol Sci 281:46-50. 2009
    ..The present study provided first behavioral evidence that fatigue and executive control are uniquely related in MS...
  9. ncbi request reprint Predicting age-related dual-task effects with individual differences on neuropsychological tests
    Roee Holtzer
    Cognitive Neuroscience Division of the Taub Institute, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Neuropsychology 19:18-27. 2005
    ..The authors conclude that compromised central executive may underlie age-related decline in dual-task performance...
  10. pmc Egocentric and exocentric navigation skills in older adults
    Amy E Sanders
    Albert Einstein College of Medicine, Bronx, NY 10461, USA
    J Gerontol A Biol Sci Med Sci 63:1356-63. 2008
    ..Our objective was to develop tests of navigation and study their cognitive correlates in nondemented older adults...
  11. pmc Self-reported difficulty in climbing up or down stairs in nondisabled elderly
    Joe Verghese
    Department of Neurology, Albert Einstein College of Medicine, Yeshiva University, Bronx, NY 10461, USA
    Arch Phys Med Rehabil 89:100-4. 2008
    ..To examine clinical and functional correlates of self-reported difficulty in climbing up or climbing down stairs in older adults...
  12. pmc Quantitative gait dysfunction and risk of cognitive decline and dementia
    Joe Verghese
    Department of Neurology, Albert Einstein College of Medicine, 1165 Morris Park Avenue, Room 338, Bronx, New York 10461, USA
    J Neurol Neurosurg Psychiatry 78:929-35. 2007
    ..Identifying quantitative gait markers of preclinical dementia may lead to new insights into early disease stages, improve diagnostic assessments and identify new preventive strategies...
  13. pmc Walking while talking: effect of task prioritization in the elderly
    Joe Verghese
    Department of Neurology, Albert Einstein College of Medicine, Yeshiva University, Bronx, NY, USA
    Arch Phys Med Rehabil 88:50-3. 2007
    ..To examine the effect of 2 instructions on the same walking while talking (WWT) task on task prioritization by nondisabled subjects...
  14. pmc Quantitative gait markers and incident fall risk in older adults
    Joe Verghese
    MBBS, Einstein Aging Study, Albert Einstein College of Medicine, Yeshiva University, 1165 Morris Park Avenue, Room 338, Bronx, NY 10461, USA
    J Gerontol A Biol Sci Med Sci 64:896-901. 2009
    ..Identifying quantitative gait markers of falls in older adults may improve diagnostic assessments and suggest novel intervention targets...
  15. doi request reprint Effect of cognitive remediation on gait in sedentary seniors
    Joe Verghese
    Department of Neurology, Albert Einstein College of Medicine, Yeshiva University, 1165 Morris Park Avenue, Bronx, NY 10461, USA
    J Gerontol A Biol Sci Med Sci 65:1338-43. 2010
    ..However, cognitive remediation as a strategy to improve mobility has not been investigated...
  16. pmc Gait dysfunction in mild cognitive impairment syndromes
    Joe Verghese
    Department of Neurology, Einstein Aging Study, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    J Am Geriatr Soc 56:1244-51. 2008
    ..To conduct a systematic clinical and quantitative assessment of gait in older adults with mild cognitive impairment (MCI) syndromes...
  17. doi request reprint Ictal mnemestic aura and verbal memory function
    Aaron C Vederman
    New York University Comprehensive Epilepsy Center, New York, NY, USA
    Epilepsy Behav 17:474-7. 2010
    ..Mnemestic auras were associated with clinical indices of illness, suggesting that the presence of these auras may be regarded as a risk factor for greater chronicity and severity in epilepsy...
  18. pmc Homocysteine and mobility in older adults
    Lydia Rolita
    Department of General Internal Medicine, New York University School of Medicine, New York, New York 10461, USA
    J Am Geriatr Soc 58:545-50. 2010
    ..To determine the influence of homocysteine on mobility decline in older adults...
  19. pmc Conventional and robust quantitative gait norms in community-dwelling older adults
    Mooyeon Oh-Park
    Department of Physical Medicine and Rehabilitation, Albert Einstein College of Medicine, Bronx, New York, USA
    J Am Geriatr Soc 58:1512-8. 2010
    ..To develop and compare norms for widely used gait parameters in adults aged 70 and older using cross-sectional (conventional) and longitudinal (robust) approaches accounting for important confounders such as disease effects on gait...
  20. pmc A common neural network for cognitive reserve in verbal and object working memory in young but not old
    Yaakov Stern
    Cognitive Neuroscience Division of the Taub Institute, NY, USA
    Cereb Cortex 18:959-67. 2008
    ..This spatial pattern could represent a general neural instantiation of CR that is affected by the aging process...
  21. ncbi request reprint Depressive symptoms in Alzheimer's disease: natural course and temporal relation to function and cognitive status
    Roee Holtzer
    Cognitive Neuroscience Division, Taub Institute, G H Gertrude Sergievsky Center and Department of Neurology, College of Physicians and Surgeons, Columbia University Medical Center, New York, New York 10032, USA
    J Am Geriatr Soc 53:2083-9. 2005
    ..To examine the natural course of depressive symptoms in patients with probable Alzheimer's disease (AD), specifically, the temporal relationship between depressive symptoms, function, and cognitive status...
  22. ncbi request reprint The sensitivity of dual-task performance to cognitive status in aging
    Roee Holtzer
    Cognitive Neuroscience Division of the Taub Institute, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    J Int Neuropsychol Soc 10:230-8. 2004
    ..jins, 2004, 10, 230-238.)..
  23. ncbi request reprint The rate of cognitive decline and risk of reaching clinical milestones in Alzheimer disease
    Roee Holtzer
    Sergievsky Center, Columbia University College of Physicians and Surgeons, 630 W 168th Street, New York, NY 10032, USA
    Arch Neurol 60:1137-42. 2003
    ..However, the relationship between the rate of cognitive decline at the initial disease phase and the risk of reaching clinical milestones in subsequent years has not yet been examined...
  24. ncbi request reprint Psychopathological features in Alzheimer's disease: course and relationship with cognitive status
    Roee Holtzer
    Sergievsky Center, New York, New York 10032, USA
    J Am Geriatr Soc 51:953-60. 2003
    ..To examine the course, clinical correlates, and relationship between cognitive status and psychopathological features in patients with probable Alzheimer's disease (AD) followed over a 5-year period...
  25. ncbi request reprint Relation of quantitative indexes of concurrent alpha-synuclein abnormalities to clinical outcome in autopsy-proven Alzheimer disease
    Roee Holtzer
    Sergievsky Center, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Arch Neurol 63:226-30. 2006
    ..Most studies used semiquantitative measures to determine the presence or absence of LB abnormalities...
  26. ncbi request reprint Age-related differences in executive control of working memory
    Roee Holtzer
    Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Mem Cognit 32:1333-45. 2004
    ..The degree of temporal overlap between individual tasks and the sensitivity of specific memory operations to interference should be considered, as well...

Research Grants2

  1. Predictors of Gait and Falls in Aging: Linking Cognitive Control to Genes
    Roee Holtzer; Fiscal Year: 2007
    ..We believe that this theory driven application will provide valuable insights into risk assessment, as well as rehabilitative and pharmacological interventions for individuals at risk of decline in gait and falls. ..