Research Topics
Genomes and GenesSpecies | MARC JAMES GUNTERSummaryAffiliation: Albert Einstein College of Medicine Country: USA Publications
Research Grants
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Publications
Insulin, insulin-like growth factor-I, endogenous estradiol, and risk of colorectal cancer in postmenopausal womenMarc J Gunter
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York 10461, USA
Cancer Res 68:329-37. 2008....
A prospective evaluation of insulin and insulin-like growth factor-I as risk factors for endometrial cancerMarc J Gunter
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, NY 10461, USA
Cancer Epidemiol Biomarkers Prev 17:921-9. 2008..Free IGF-I levels were inversely associated with endometrioid adenocarcinoma, consistent with prior cross-sectional data...
Insulin resistance-related genes and advanced left-sided colorectal adenomaMarc J Gunter
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
Cancer Epidemiol Biomarkers Prev 16:703-8. 2007....- Leukocyte polycyclic aromatic hydrocarbon-DNA adduct formation and colorectal adenomaMarc J Gunter
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Division of Health and Human Services, Bethesda, MD 20852, USA
Carcinogenesis 28:1426-9. 2007..8 (95% CI, 1.2-6.5; P(trend) = 0.048) for risk of colorectal adenoma. These data support a link between PAH exposure and colorectal adenoma... - Insulin, insulin-like growth factor-I, and risk of breast cancer in postmenopausal womenMarc J Gunter
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, New York, NY 10461, USA
J Natl Cancer Inst 101:48-60. 2009..However, no prospective studies have directly assessed associations between circulating levels of insulin and/or insulin-like growth factor (IGF)-I, a related hormone, and the risk of breast cancer independent of estrogen level... - Inflammation-related gene polymorphisms and colorectal adenomaMarc J Gunter
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, USA
Cancer Epidemiol Biomarkers Prev 15:1126-31. 2006..7; 95% CI, 0.3-1.5; P(interaction) = 0.01). These exploratory data provide evidence that polymorphic variation in genes that regulate inflammation could alter risk for colorectal adenoma... - Tissue microarray analysis of hormonal signaling pathways in uterine carcinosarcomaGloria S Huang
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology and Women s Health, Albert Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, NY, USA
Am J Obstet Gynecol 200:457.e1-5. 2009.... - Adipokine genes and prostate cancer riskSteven C Moore
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Int J Cancer 124:869-76. 2009..05). Polymorphisms in the IL6, LEPR, TNF and ADIPOQ genes were not associated with prostate cancer. Allelic variants in the LEP gene are related to prostate cancer risk, supporting a role for leptin in prostate carcinogenesis... - Iron and colorectal cancer risk in the alpha-tocopherol, beta-carotene cancer prevention studyAmanda J Cross
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD, USA
Int J Cancer 118:3147-52. 2006..7, 95% CI = 1.4-15.1, p trend = 0.009). In summary, we found a significant inverse association between several serum iron indices and colon cancer risk... - Repeated measures of serum glucose and insulin in relation to postmenopausal breast cancerGeoffrey C Kabat
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
Int J Cancer 125:2704-10. 2009..Analysis of the repeated measurements supported the results of the baseline analysis. These data suggest that elevated serum insulin levels may be a risk factor for postmenopausal breast cancer... - Co-expression of GPR30 and ERbeta and their association with disease progression in uterine carcinosarcomaGloria S Huang
Department of Obstetrics and Gynecology and Women s Health, Division of Gynecologic Oncology, Albert Einstein College of Medicine and Montefiore Medical Center Bronx, NY, USA
Am J Obstet Gynecol 203:242.e1-5. 2010..We sought to evaluate the expression of G protein-coupled receptor 30 (GPR30) and estrogen receptor (ER)beta in uterine carcinosarcoma (CS)... - A prospective evaluation of C-reactive protein levels and colorectal adenoma developmentMarc J Gunter
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York, NY 10461, USA
Cancer Epidemiol Biomarkers Prev 20:537-44. 2011.... - Associations of insulin-like growth factor (IGF)-I and IGF-binding protein-3 with HIV disease progression in womenHoward D Strickler
Albert Einstein College of Medicine, Bronx, New York 10461, USA
J Infect Dis 197:319-27. 2008.... - A prospective study of inflammation markers and endometrial cancer risk in postmenopausal hormone nonusersTao Wang
Division of Biostatistics, Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
Cancer Epidemiol Biomarkers Prev 20:971-7. 2011..We examined the associations of three inflammation markers, C-reactive protein (CRP), interleukin (IL)-6 and tumor necrosis factor (TNF)-α, with risk of endometrial cancer... - Serum CA125 predicts extrauterine disease and survival in uterine carcinosarcomaGloria S Huang
Department of Obstetrics and Gynecology and Women s Health, Division of Gynecologic Oncology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York 10461, USA
Gynecol Oncol 107:513-7. 2007..The purpose of this study was to determine the clinical utility of CA125 measurement in patients with uterine carcinosarcoma (CS)... - Insulin resistance-related gene polymorphisms and risk of prostate cancerSteven C Moore
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland 20892, USA
Cancer Epidemiol Biomarkers Prev 16:1315-7. 2007 - Obesity and colorectal cancer: epidemiology, mechanisms and candidate genesMarc J Gunter
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20852, USA
J Nutr Biochem 17:145-56. 2006..These pathways will be discussed with particular reference to genetic polymorphisms that have been associated with obesity and insulin resistance... - Dietary benzo[a]pyrene intake and risk of colorectal adenomaRashmi Sinha
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD, USA
Cancer Epidemiol Biomarkers Prev 14:2030-4. 2005..21 (1.79-9.91) for the third quintile, 2.45 (0.98-6.12) for the fourth quintile, and 5.60 (2.20-14.20) for the fifth quintile (Ptrend=0.002). This study provides evidence that dietary BaP plays a role in colorectal adenoma etiology... - Meat intake, cooking-related mutagens and risk of colorectal adenoma in a sigmoidoscopy-based case-control studyMarc J Gunter
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, EPS, 6120 Executive Boulevard, Rockville, MD 20852, USA
Carcinogenesis 26:637-42. 2005..49 (95% CI, 0.28-0.85)]. We did not identify any association with consumption of individual HCAs and colorectal adenoma risk. These results support the hypothesis that BP contributes to colorectal carcinogenesis... - The role of insulin-like growth factor-I and its binding proteins in glucose homeostasis and type 2 diabetesSwapnil N Rajpathak
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx NY 10461, USA
Diabetes Metab Res Rev 25:3-12. 2009..Large prospective studies are required to evaluate this association... - A prospective study of serum C-reactive protein and colorectal cancer risk in menMarc J Gunter
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20852, USA
Cancer Res 66:2483-7. 2006..018). These results support the notion that chronic low-grade inflammation is a marker for increased risk of colorectal cancer... - MTHFR (C677T and A1298C) polymorphisms and risk of sporadic distal colorectal adenoma in the UK Flexible Sigmoidoscopy Screening Trial (United Kingdom)Panagiota N Mitrou
Dunn Human Nutrition Unit, MRC Wellcome Trust Building, Hills Road, Cambridge, CB2 2XY, UK
Cancer Causes Control 17:793-801. 2006..The purpose of this study was to further evaluate the role of low activity MTHFR variants as well as to explore interactive effects between alcoholic drink consumption and MTHFR variants and risk of distal colorectal adenomatous polyps... - Role of NQO1C609T and EPHX1 gene polymorphisms in the association of smoking and alcohol with sporadic distal colorectal adenomas: results from the UKFSS StudyPanagiota N Mitrou
Dunn Human Nutrition Unit, MRC Wellcome Trust Building, Hills Road, Cambridge CB2 2XY, UK
Carcinogenesis 28:875-82. 2007..Alcohol increases risk of colorectal adenoma in carriers of the high-activity genotype possibly through enhanced activation of alcohol-related procarcinogens... - No association between cytochrome P450 and glutathione S-transferase gene polymorphisms and risk of colorectal adenoma: results from the UK Flexible Sigmoidoscopy Screening TrialMarc J Gunter
Dunn Human Nutrition Unit, Medical Research Council, MRC/Wellcome Trust Building, Hills Road, Cambridge CB2 2XY, United Kingdom
Cancer Epidemiol Biomarkers Prev 14:1028-30. 2005
Research Grants
- Role of the Sex Hormones and Insulin/IGF-Axes in Endometrial Cancer RecurrenceMarc Gunter; Fiscal Year: 2009..The study will be conducted in a large, prospective cohort study of endometrial cancer (GOG-0210). ..
- Role of the Sex Hormones and Insulin/IGF-Axes in Endometrial Cancer RecurrenceMARC JAMES GUNTER; Fiscal Year: 2010..The study will be conducted in a large, prospective cohort study of endometrial cancer (GOG-0210). ..