Affiliation: Albert Einstein College of Medicine
- Acute ablation of PERK results in ER dysfunctions followed by reduced insulin secretion and cell proliferationDaorong Feng
Department of Biology, Pennsylvania State University, University Park, PA 16802, USA
BMC Cell Biol 10:61. 2009..The aim of this study was to determine if acute ablation of PERK in the 832/13 beta cells recapitulates these defects and to identify the primary molecular basis for beta cell dysfunction...