MARTA L FELDMESSER

Summary

Affiliation: Albert Einstein College of Medicine
Country: USA

Publications

  1. pmc Eosinophil-Cryptococcus neoformans interactions in vivo and in vitro
    M Feldmesser
    Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461 1602, USA
    Infect Immun 65:1899-907. 1997
  2. ncbi request reprint Prospects of vaccines for invasive aspergillosis
    Marta Feldmesser
    Division of Infectious Diseases, Department of Medicine, Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Med Mycol 43:571-87. 2005
  3. ncbi request reprint New and emerging antifungal agents: impact on respiratory infections
    Marta Feldmesser
    Departments of Medicine and Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Am J Respir Med 2:371-83. 2003
  4. pmc Antibody-mediated protection in murine Cryptococcus neoformans infection is associated with pleotrophic effects on cytokine and leukocyte responses
    Marta Feldmesser
    Division of Infectious Diseases, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Infect Immun 70:1571-80. 2002
  5. ncbi request reprint Dynamic changes in the morphology of Cryptococcus neoformans during murine pulmonary infection
    M Feldmesser
    Department of Medicine, Division of Infectious Diseases, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Microbiology 147:2355-65. 2001
  6. pmc Intracellular crystal formation as a mechanism of cytotoxicity in murine pulmonary Cryptococcus neoformans infection
    M Feldmesser
    Division of Infectious Diseases, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Infect Immun 69:2723-7. 2001
  7. ncbi request reprint The effect of the echinocandin analogue caspofungin on cell wall glucan synthesis by Cryptococcus neoformans
    M Feldmesser
    Dept of Medicine, Division of Infectious Diseases, Albert Einstein College of Medicine, Golding Bldg, Bronx, NY 10461, USA
    J Infect Dis 182:1791-5. 2000
  8. pmc Cryptococcus neoformans is a facultative intracellular pathogen in murine pulmonary infection
    M Feldmesser
    Department of Medicine, Division of Infectious Diseases, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Infect Immun 68:4225-37. 2000
  9. ncbi request reprint Effect of antibody to capsular polysaccharide on eosinophilic pneumonia in murine infection with Cryptococcus neoformans
    M Feldmesser
    Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    J Infect Dis 177:1639-46. 1998
  10. pmc Role of neutrophils in invasive aspergillosis
    Marta Feldmesser
    Albert Einstein College of Medicine, Forchheimer Building, Room 402, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Infect Immun 74:6514-6. 2006

Research Grants

Collaborators

Detail Information

Publications10

  1. pmc Eosinophil-Cryptococcus neoformans interactions in vivo and in vitro
    M Feldmesser
    Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461 1602, USA
    Infect Immun 65:1899-907. 1997
    ..Mast cells were observed to occasionally phagocytose C. neoformans in vitro in the presence of IgE MAb. Our observations suggest that eosinophils may be effector cells against C. neoformans...
  2. ncbi request reprint Prospects of vaccines for invasive aspergillosis
    Marta Feldmesser
    Division of Infectious Diseases, Department of Medicine, Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Med Mycol 43:571-87. 2005
    ..Strategies using antigen-exposed dendritic cells as adjuvants appear to be particularly promising. Though we currently are far away from a candidate that is applicable for human trials, recent progress is encouraging...
  3. ncbi request reprint New and emerging antifungal agents: impact on respiratory infections
    Marta Feldmesser
    Departments of Medicine and Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Am J Respir Med 2:371-83. 2003
    ..However, at the present time, our ability to assess their impact is limited by the problematic nature of conducting trials for antifungal therapy...
  4. pmc Antibody-mediated protection in murine Cryptococcus neoformans infection is associated with pleotrophic effects on cytokine and leukocyte responses
    Marta Feldmesser
    Division of Infectious Diseases, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Infect Immun 70:1571-80. 2002
    ..MAb may function partly by down-regulating the inflammatory response and reducing host damage. Our findings demonstrate unexpected complexity in the interaction between specific MAb and other components of the host immune response...
  5. ncbi request reprint Dynamic changes in the morphology of Cryptococcus neoformans during murine pulmonary infection
    M Feldmesser
    Department of Medicine, Division of Infectious Diseases, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Microbiology 147:2355-65. 2001
    ..The results indicate that the population of C. neoformans cells in tissue is in a highly dynamic state, implying that the immune system must confront cells with varying characteristics during the course of infection...
  6. pmc Intracellular crystal formation as a mechanism of cytotoxicity in murine pulmonary Cryptococcus neoformans infection
    M Feldmesser
    Division of Infectious Diseases, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Infect Immun 69:2723-7. 2001
    ..The crystals apparently formed because of the interaction of a host protein with the cryptococcal polysaccharide. Crystal formation likely contributes to pathogenesis by causing cellular damage...
  7. ncbi request reprint The effect of the echinocandin analogue caspofungin on cell wall glucan synthesis by Cryptococcus neoformans
    M Feldmesser
    Dept of Medicine, Division of Infectious Diseases, Albert Einstein College of Medicine, Golding Bldg, Bronx, NY 10461, USA
    J Infect Dis 182:1791-5. 2000
    ..neoformans may result from reduced activity against C. neoformans glucan synthase or from yet undiscovered mechanisms of action operative in other fungal pathogens but not in C. neoformans...
  8. pmc Cryptococcus neoformans is a facultative intracellular pathogen in murine pulmonary infection
    M Feldmesser
    Department of Medicine, Division of Infectious Diseases, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Infect Immun 68:4225-37. 2000
    ..Furthermore, our observations suggest that C. neoformans occupies a unique niche among the intracellular pathogens whereby survival in phagocytic cells is accompanied by intracellular polysaccharide production...
  9. ncbi request reprint Effect of antibody to capsular polysaccharide on eosinophilic pneumonia in murine infection with Cryptococcus neoformans
    M Feldmesser
    Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    J Infect Dis 177:1639-46. 1998
    ..Our results provide additional evidence that antibody administration can produce quantitative and qualitative changes in the inflammatory response to a pathogen...
  10. pmc Role of neutrophils in invasive aspergillosis
    Marta Feldmesser
    Albert Einstein College of Medicine, Forchheimer Building, Room 402, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Infect Immun 74:6514-6. 2006

Research Grants7

  1. Monoclonal antibodies to inhibit Aspergillus germination
    MARTA L FELDMESSER; Fiscal Year: 2010
    ..It is anticipated that this study will identify fungal molecules important for germination and begin to define their interaction with host immune responses. ..
  2. Monoclonal antibodies for invasive aspergillosis
    Marta Feldmesser; Fiscal Year: 2003
    ..To determine the biological activity of MAbs generated in Aim 2 in murine models of invasive aspergillosis. It is anticipated that this study will identify important targets for further investigation. ..
  3. Monoclonal antibodies to inhibit Aspergillus germination
    Marta Feldmesser; Fiscal Year: 2006
    ..It is anticipated that this study will identify fungal molecules important for germination and begin to define their interaction with host immune responses. ..
  4. Aspergillosis: Engineering Antibody for Diagnosis
    Marta Feldmesser; Fiscal Year: 2006
    ..The availability of reagents that have potential to improve both sensitivity and specificity of galactomannan detection would be a significant advance. ..
  5. Monoclonal antibodies to inhibit Aspergillus germination
    Marta Feldmesser; Fiscal Year: 2007
    ..It is anticipated that this study will identify fungal molecules important for germination and begin to define their interaction with host immune responses. ..
  6. Monoclonal antibodies to inhibit Aspergillus germination
    Marta Feldmesser; Fiscal Year: 2009
    ..It is anticipated that this study will identify fungal molecules important for germination and begin to define their interaction with host immune responses. ..