Melissa J Fazzari
Affiliation: Albert Einstein College of Medicine
- Epigenomics: beyond CpG islandsMelissa J Fazzari
Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine, Bronx, New York 10461, USA
Nat Rev Genet 5:446-55. 2004
- Clinical application of molecular profiling in breast cancerJoseph A Sparano
Montefiore Einstein Cancer Center, Albert Einstein College of Medicine, Room 47, 1825 Eastchester Road, 2 South, Bronx, NY 10461, USA
Future Oncol 1:485-96. 2005..The completion of these important studies will represent the first step toward integrating molecular profiling into treatment selection for adjuvant therapy in breast cancer...
- Comparative isoschizomer profiling of cytosine methylation: the HELP assayBatbayar Khulan
Department of Molecular Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA
Genome Res 16:1046-55. 2006..The HELP assay is robust, quantitative, and accurate and is providing new insights into the distribution and dynamic nature of cytosine methylation in the genome...
- Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequencesTarjei S Mikkelsen
Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA
Nature 447:167-77. 2007..A substantial proportion of these eutherian-specific CNEs arose from sequence inserted by transposable elements, pointing to transposons as a major creative force in the evolution of mammalian gene regulation...
- CG dinucleotide clustering is a species-specific property of the genomeJacob L Glass
Department of Molecular Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA, Division of Hematology Oncology, University of Kentucky, Markey Cancer Center, 800 Rose Street, Lexington KY 40536, USA
Nucleic Acids Res 35:6798-807. 2007..Finally, our approach is able to identify methylating genomes (such as Takifugu rubripes) that lack CG clustering entirely, in which it is inappropriate to annotate CpG islands or CG clusters...