Mariana Dabeva

Summary

Affiliation: Albert Einstein College of Medicine
Country: USA

Publications

  1. ncbi Hepatic stem cells and liver repopulation
    Mariana D Dabeva
    Department of Medicine, Albert Einstein College of Medicine, Marion Bessin Liver Research Center, Bronx, New York 10461, USA
    Semin Liver Dis 23:349-62. 2003
  2. ncbi Liver stem cells and model systems for liver repopulation
    David A Shafritz
    Marion Bessin Liver Research Center, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    J Hepatol 36:552-64. 2002
  3. ncbi Cell competition leads to a high level of normal liver reconstitution by transplanted fetal liver stem/progenitor cells
    Michael Oertel
    Marion Bessin Liver Research Center, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York 10461, USA
    Gastroenterology 130:507-20; quiz 590. 2006
  4. ncbi Expression and localization of PCSK9 in rat hepatic cells
    Petar N Grozdanov
    Marion Bessin Liver Research Center, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Biochem Cell Biol 84:80-92. 2006
  5. ncbi Liver stem cells and prospects for liver reconstitution by transplanted cells
    David A Shafritz
    Marion Bessin Liver Research Center, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Hepatology 43:S89-98. 2006
  6. ncbi Bone marrow progenitors are not the source of expanding oval cells in injured liver
    Anuradha Menthena
    Marion Bessin Liver Research Center, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA
    Stem Cells 22:1049-61. 2004
  7. ncbi Gene expression pattern in hepatic stem/progenitor cells during rat fetal development using complementary DNA microarrays
    Petko M Petkov
    Marion Bessin Liver Research Center, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Hepatology 39:617-27. 2004
  8. ncbi Repopulation of rat liver by fetal hepatoblasts and adult hepatocytes transduced ex vivo with lentiviral vectors
    Michael Oertel
    Marion Bessin Liver Research Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Hepatology 37:994-1005. 2003
  9. ncbi Identification of adult hepatic progenitor cells capable of repopulating injured rat liver
    Mladen I Yovchev
    Marion Bessin Liver Research Center, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Hepatology 47:636-47. 2008
  10. ncbi HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver
    Orit Kollet
    Department of Immunology, Weizmann Institute of Science, Rehovot 76100, Israel
    J Clin Invest 112:160-9. 2003

Research Grants

  1. ORIGIN AND ISOLATION OF LIVER PROGENITOR CELLS
    Mariana Dabeva; Fiscal Year: 2003
  2. Gene Expression Pattern of Liver Stem/Progenitor Cells
    Mariana Dabeva; Fiscal Year: 2006

Collaborators

  • David A Shafritz
  • Michael Oertel
  • Sanjeev Gupta
  • T Lapidot
  • Petar N Grozdanov
  • Mladen I Yovchev
  • Petko M Petkov
  • Chandan Guha
  • Anuradha Menthena
  • Orit Kollet
  • Hongchao Zhou
  • Harini Racherla
  • Brigid Joseph
  • L K Karagyozov
  • David Goetz
  • Robert Carver
  • Niloyjyoti Deb
  • Erwin P Bottinger
  • Charles E Rogler
  • Jaswinder Sandhu
  • Tearina Chu
  • Shalin Shah
  • Jiri Zavadil
  • Izhar Hardan
  • Swan N Thung
  • Polina Goichberg
  • Fernando Arenzana-Seisdedos
  • Yuan-Qing Chen
  • Sarit Samira
  • Yuan Qing Chen
  • Joy Kahn
  • Arnon Nagler
  • Michel Revel
  • Ayelet Dar
  • Shoham Shivtiel
  • Jenny Suriawinata
  • Asaf Spiegel
  • Alexander Kalinkovich

Detail Information

Publications12

  1. ncbi Hepatic stem cells and liver repopulation
    Mariana D Dabeva
    Department of Medicine, Albert Einstein College of Medicine, Marion Bessin Liver Research Center, Bronx, New York 10461, USA
    Semin Liver Dis 23:349-62. 2003
    ..Multilineage adult progenitor cells of mesenchymal origin from bone marrow, muscle, and brain may turn out to be the long-sought primitive potential stem cells remaining in adult tissues...
  2. ncbi Liver stem cells and model systems for liver repopulation
    David A Shafritz
    Marion Bessin Liver Research Center, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    J Hepatol 36:552-64. 2002
  3. ncbi Cell competition leads to a high level of normal liver reconstitution by transplanted fetal liver stem/progenitor cells
    Michael Oertel
    Marion Bessin Liver Research Center, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York 10461, USA
    Gastroenterology 130:507-20; quiz 590. 2006
    ....
  4. ncbi Expression and localization of PCSK9 in rat hepatic cells
    Petar N Grozdanov
    Marion Bessin Liver Research Center, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Biochem Cell Biol 84:80-92. 2006
    ..In conclusion, our results show that PCSK9 is processed in the ER, and the mature convertase is secreted in the plasma...
  5. ncbi Liver stem cells and prospects for liver reconstitution by transplanted cells
    David A Shafritz
    Marion Bessin Liver Research Center, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Hepatology 43:S89-98. 2006
    ....
  6. ncbi Bone marrow progenitors are not the source of expanding oval cells in injured liver
    Anuradha Menthena
    Marion Bessin Liver Research Center, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA
    Stem Cells 22:1049-61. 2004
    ..These data demonstrate that the sources of oval cells and small hepatocytes in the injured liver are endogenous liver progenitors and that they do not arise through transdifferentiation from BM cells...
  7. ncbi Gene expression pattern in hepatic stem/progenitor cells during rat fetal development using complementary DNA microarrays
    Petko M Petkov
    Marion Bessin Liver Research Center, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Hepatology 39:617-27. 2004
    ..Supplementary material for this article can be found on the HEPATOLOGY website (http://interscience.wiley.com/jpages/0270-9139/suppmat/index.html)...
  8. ncbi Repopulation of rat liver by fetal hepatoblasts and adult hepatocytes transduced ex vivo with lentiviral vectors
    Michael Oertel
    Marion Bessin Liver Research Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Hepatology 37:994-1005. 2003
    ....
  9. ncbi Identification of adult hepatic progenitor cells capable of repopulating injured rat liver
    Mladen I Yovchev
    Marion Bessin Liver Research Center, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Hepatology 47:636-47. 2008
    ..These cells display a mixed epithelial/mesenchymal phenotype that has not been recognized previously. They are valuable candidates for liver cell therapy...
  10. ncbi HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver
    Orit Kollet
    Department of Immunology, Weizmann Institute of Science, Rehovot 76100, Israel
    J Clin Invest 112:160-9. 2003
    ..Our results suggest the potential of hematopoietic CD34+/CXCR4+cells to respond to stress signals from nonhematopoietic injured organs as an important mechanism for tissue targeting and repair...
  11. ncbi The oncofetal protein glypican-3 is a novel marker of hepatic progenitor/oval cells
    Petar N Grozdanov
    Department of Medicine, Marion Bessin Liver Research Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Lab Invest 86:1272-84. 2006
    ..Our findings show further that hepatic progenitor/oval cells are the target for malignant transformation in the Solt-Farber model of hepatic carcinogenesis...
  12. ncbi Novel hepatic progenitor cell surface markers in the adult rat liver
    Mladen I Yovchev
    Marion Bessin Liver Research Center, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Hepatology 45:139-49. 2007
    ..Our studies also reveal the mesenchymal/epithelial phenotype of these cells and the existence of species diversity in the hepatic progenitor cell identity...

Research Grants6

  1. ORIGIN AND ISOLATION OF LIVER PROGENITOR CELLS
    Mariana Dabeva; Fiscal Year: 2003
    ..A combination of these markers will be designed that is expressed only in liver progenitor/oval cells. This panel of markers will be then used for isolation of liver progenitor cells from the liver. ..
  2. Gene Expression Pattern of Liver Stem/Progenitor Cells
    Mariana Dabeva; Fiscal Year: 2006
    ..abstract_text> ..