J Condeelis

Summary

Affiliation: Albert Einstein College of Medicine
Country: USA

Publications

  1. pmc Rapid chemokinetic movement and the invasive potential of lung cancer cells; a functional molecular study
    Kam Meng Tchou-Wong
    Departments of Medicine and Environmental Medicine, Division of Pulmonary and Critical Care Medicine, NYU School of Medicine, New York, NY, USA
    BMC Cancer 6:151. 2006
  2. pmc Gene expression analysis on small numbers of invasive cells collected by chemotaxis from primary mammary tumors of the mouse
    Weigang Wang
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    BMC Biotechnol 3:13. 2003
  3. pmc Simultaneous imaging of GFP, CFP and collagen in tumors in vivo using multiphoton microscopy
    Erik Sahai
    Tumour Cell Biology Laboratory, Cancer Research UK London Research Institute, London WC2A 3PX, UK
    BMC Biotechnol 5:14. 2005
  4. ncbi request reprint The great escape: when cancer cells hijack the genes for chemotaxis and motility
    John Condeelis
    Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York 10461 1975, USA
    Annu Rev Cell Dev Biol 21:695-718. 2005
  5. ncbi request reprint Macrophages: obligate partners for tumor cell migration, invasion, and metastasis
    John Condeelis
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Cell 124:263-6. 2006
  6. ncbi request reprint Intravital imaging of cell movement in tumours
    John Condeelis
    Department of Anatomy and Structural Biology, Program in Motility and Invasion, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Nat Rev Cancer 3:921-30. 2003
  7. pmc In vivo imaging in cancer
    John Condeelis
    Anatomy and Structural Biology, Gruss Lipper Biophotonics Center, Program in Microenvironment and Metastasis, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York 10461, USA
    Cold Spring Harb Perspect Biol 2:a003848. 2010
  8. ncbi request reprint How is actin polymerization nucleated in vivo?
    J Condeelis
    Albert Einstein College of Medicine, Anatomy and Structural Biology, 1300 10461, Morris Park Avenue, NY, USA
    Trends Cell Biol 11:288-93. 2001
  9. ncbi request reprint Single cell behavior in metastatic primary mammary tumors correlated with gene expression patterns revealed by molecular profiling
    Weigang Wang
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Cancer Res 62:6278-88. 2002
  10. ncbi request reprint Tumor cells caught in the act of invading: their strategy for enhanced cell motility
    Weigang Wang
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Trends Cell Biol 15:138-45. 2005

Research Grants

Collaborators

Detail Information

Publications39

  1. pmc Rapid chemokinetic movement and the invasive potential of lung cancer cells; a functional molecular study
    Kam Meng Tchou-Wong
    Departments of Medicine and Environmental Medicine, Division of Pulmonary and Critical Care Medicine, NYU School of Medicine, New York, NY, USA
    BMC Cancer 6:151. 2006
    ..In this study, we test the hypothesis that heterogeneous cancer cells exhibit variable motility responses such as chemokinesis and chemotaxis that can be characterized molecularly...
  2. pmc Gene expression analysis on small numbers of invasive cells collected by chemotaxis from primary mammary tumors of the mouse
    Weigang Wang
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    BMC Biotechnol 3:13. 2003
    ..We have combined chemotaxis-based cell collection of the invasive subpopulation of cells within the primary tumor with array-based gene expression analysis to identify the genes necessary for the process of carcinoma cell invasion...
  3. pmc Simultaneous imaging of GFP, CFP and collagen in tumors in vivo using multiphoton microscopy
    Erik Sahai
    Tumour Cell Biology Laboratory, Cancer Research UK London Research Institute, London WC2A 3PX, UK
    BMC Biotechnol 5:14. 2005
    ..However, the use of genetically encoded fluorescent proteins to distinguish different cell types in living animals has not been described at single cell resolution using multiphoton microscopy...
  4. ncbi request reprint The great escape: when cancer cells hijack the genes for chemotaxis and motility
    John Condeelis
    Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York 10461 1975, USA
    Annu Rev Cell Dev Biol 21:695-718. 2005
    ..We discuss how these new insights may lead to a better understanding of the molecular basis of the invasive behavior of tumor cells in vivo, which may result in new strategies for the diagnosis and treatment of metastasis...
  5. ncbi request reprint Macrophages: obligate partners for tumor cell migration, invasion, and metastasis
    John Condeelis
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Cell 124:263-6. 2006
    ..Thus, macrophages are at the center of the invasion microenvironment and are an important drug target for cancer therapy...
  6. ncbi request reprint Intravital imaging of cell movement in tumours
    John Condeelis
    Department of Anatomy and Structural Biology, Program in Motility and Invasion, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Nat Rev Cancer 3:921-30. 2003
  7. pmc In vivo imaging in cancer
    John Condeelis
    Anatomy and Structural Biology, Gruss Lipper Biophotonics Center, Program in Microenvironment and Metastasis, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York 10461, USA
    Cold Spring Harb Perspect Biol 2:a003848. 2010
    ..Examples of new insights derived from the different scales of imaging and relevant probes are discussed in the context of cancer progression and metastasis...
  8. ncbi request reprint How is actin polymerization nucleated in vivo?
    J Condeelis
    Albert Einstein College of Medicine, Anatomy and Structural Biology, 1300 10461, Morris Park Avenue, NY, USA
    Trends Cell Biol 11:288-93. 2001
    ..These results highlight the need for new methods that enable the direct observation of actin nucleation and so define precisely the relative contributions of the three processes to stimulated cell motility...
  9. ncbi request reprint Single cell behavior in metastatic primary mammary tumors correlated with gene expression patterns revealed by molecular profiling
    Weigang Wang
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Cancer Res 62:6278-88. 2002
    ..We conclude that aligning cell behavior in vivo with patterns of gene expression can lead to new insights into the microenvironment of carcinoma cells in the primary tumor and the molecular mechanisms behind cell behavior...
  10. ncbi request reprint Tumor cells caught in the act of invading: their strategy for enhanced cell motility
    Weigang Wang
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Trends Cell Biol 15:138-45. 2005
    ..These results support a "tumor microenvironment invasion model" and provide new target opportunities for cancer therapy...
  11. ncbi request reprint Cdc42 is required for EGF-stimulated protrusion and motility in MTLn3 carcinoma cells
    Mirvat El-Sibai
    Molecular Pharmacology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    J Cell Sci 120:3465-74. 2007
    ..Our data suggest that Cdc42 activation is crucial for the regulation of actin polymerization in carcinoma cells, and required for both EGF-stimulated protrusion and cell motility independently of effects on Rac...
  12. ncbi request reprint Cofilin promotes actin polymerization and defines the direction of cell motility
    Mousumi Ghosh
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Science 304:743-6. 2004
    ..We propose a role for cofilin that is distinct from its role as an actin-depolymerizing factor...
  13. ncbi request reprint Initiation of cofilin activity in response to EGF is uncoupled from cofilin phosphorylation and dephosphorylation in carcinoma cells
    Xiaoyan Song
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine of Yeshiva University, F628, 1300 Morris Park Avenue, Bronx, New York, NY 10461, USA
    J Cell Sci 119:2871-81. 2006
    ..Therefore, our results do not support a model for the initial activation of cofilin by dephosphorylation in response to chemoattractant stimulation in metastatic carcinoma cells...
  14. ncbi request reprint Coordinated regulation of pathways for enhanced cell motility and chemotaxis is conserved in rat and mouse mammary tumors
    Weigang Wang
    Department of Anatomy and Structural Biology and Gruss Lipper Center for Biophotonics, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Cancer Res 67:3505-11. 2007
    ....
  15. pmc Gene expression analysis of macrophages that facilitate tumor invasion supports a role for Wnt-signaling in mediating their activity in primary mammary tumors
    Laureen S Ojalvo
    Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    J Immunol 184:702-12. 2010
    ..Taken together, we conjecture that invasive TAMs link angiogenesis and tumor invasion and that Wnt-signaling plays a role in mediating their activity...
  16. pmc RhoA/ROCK-mediated switching between Cdc42- and Rac1-dependent protrusion in MTLn3 carcinoma cells
    Mirvat El-Sibai
    Department of Molecular Pharmacology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Exp Cell Res 314:1540-52. 2008
    ..These data describe a novel role for Rho in coordinating signaling by Rac and Cdc42...
  17. ncbi request reprint ZBP1 enhances cell polarity and reduces chemotaxis
    Kyle Lapidus
    Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY 10461 1975, USA
    J Cell Sci 120:3173-8. 2007
    ..We found that ZBP1 expression actually reduced tumor cell motility and chemotaxis, presumably mediating their decreased metastatic potential by reducing their ability to respond to signals necessary for invasion...
  18. pmc Invasion of human breast cancer cells in vivo requires both paracrine and autocrine loops involving the colony-stimulating factor-1 receptor
    Antonia Patsialou
    Department of Anatomy, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Cancer Res 69:9498-506. 2009
    ..In particular, we show that the autocrine contribution to invasion is specifically amplified in vivo through a tumor microenvironment-induced upregulation of CSF-1R expression via the transforming growth factor-beta1...
  19. ncbi request reprint The distinct roles of Ras and Rac in PI 3-kinase-dependent protrusion during EGF-stimulated cell migration
    Shu Chin Yip
    Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    J Cell Sci 120:3138-46. 2007
    ..These data suggest an unappreciated role for Ras during protrusion, and a crucial role for Rac in the stabilization of protrusions required for cell motility...
  20. pmc Identification of invasion specific splice variants of the cytoskeletal protein Mena present in mammary tumor cells during invasion in vivo
    Sumanta Goswami
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine of Yeshiva University, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Clin Exp Metastasis 26:153-9. 2009
    ..The Mena isoform switching pattern described here may provide a new biomarker for the presence of metastatic cancer cells and for prognosis...
  21. pmc EGF-induced PIP2 hydrolysis releases and activates cofilin locally in carcinoma cells
    Jacco van Rheenen
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, USA
    J Cell Biol 179:1247-59. 2007
    ..Moreover, our data provide evidence for how PLC is involved in the formation of protrusions in breast carcinoma cells during chemotaxis and metastasis towards EGF...
  22. doi request reprint AACR special conference on epithelial-mesenchymal transition and cancer progression and treatment
    Evanthia T Roussos
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York, USA
    Cancer Res 70:7360-4. 2010
    ..Importantly, these defining characteristics of cells undergoing EMT were discussed in the context of therapeutic and prognostic developments...
  23. pmc The activity status of cofilin is directly related to invasion, intravasation, and metastasis of mammary tumors
    Weigang Wang
    Department of Anatomy and Structural Biology and 2Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    J Cell Biol 173:395-404. 2006
    ..LIMK1-mediated decreases or increases in the activity of the cofilin pathway are shown to cause proportional decreases or increases in motility, intravasation, and metastasis of tumor cells...
  24. ncbi request reprint Over-expression of the p110beta but not p110alpha isoform of PI 3-kinase inhibits motility in breast cancer cells
    Shu Chin Yip
    Department of Molecular Pharmacology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Cell Motil Cytoskeleton 59:180-8. 2004
    ..Identification of effectors that are differently regulated by p110alpha versus p110beta will be important for understanding cell migration and its role in metastasis...
  25. ncbi request reprint Breast cancer cells isolated by chemotaxis from primary tumors show increased survival and resistance to chemotherapy
    Sumanta Goswami
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Cancer Res 64:7664-7. 2004
    ..In addition, these results indicate that tumor cells that are chemotactic and migratory in response to epidermal growth factor in the primary tumor have a survival advantage over stationary tumor cells...
  26. ncbi request reprint Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors
    Weigang Wang
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Cancer Res 64:8585-94. 2004
    ..ZBP1 reexpression also inhibited metastasis from tumors. These experiments support the involvement in metastasis of the pathways identified in invasive cells, which are regulated by ZBP1...
  27. ncbi request reprint Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/epidermal growth factor paracrine loop
    Sumanta Goswami
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Cancer Res 65:5278-83. 2005
    ..Disruption of this loop by blockade of either EGF receptor or CSF-1 receptor signaling is sufficient to inhibit both macrophage and tumor cell migration and invasion...
  28. pmc Mena deficiency delays tumor progression and decreases metastasis in polyoma middle-T transgenic mouse mammary tumors
    Evanthia T Roussos
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Breast Cancer Res 12:R101. 2010
    ..Whether Mena is required for tumor progression is still unknown. Here we report the effects of Mena deficiency on tumor progression, metastasis and on normal mammary gland development...
  29. ncbi request reprint ROCK- and myosin-dependent matrix deformation enables protease-independent tumor-cell invasion in vivo
    Jeffrey B Wyckoff
    Analytical Imaging Facility, Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA
    Curr Biol 16:1515-23. 2006
    ..Imaging of live tumors shows that MLC is organized in a similar ROCK-dependent fashion in vivo and that inhibition of ROCK but not matrix-metalloproteases reduces cancer cell motility in vivo...
  30. pmc Differential enhancement of breast cancer cell motility and metastasis by helical and kinase domain mutations of class IA phosphoinositide 3-kinase
    Huan Pang
    Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Cancer Res 69:8868-76. 2009
    ..Our observations suggest that, when compared with kinase domain mutations in a genetically identical background, expression of helical domain mutants of p110alpha produce a more severe metastatic phenotype...
  31. ncbi request reprint A new strategy for caging proteins regulated by kinases
    Mousumi Ghosh
    Department of Anatomy and Structural Biology, The Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    J Am Chem Soc 124:2440-1. 2002
    ..Photoremoval of the cage generates an active protein, which cannot be switched off by endogenous protein kinases. Caged cofilin, and its irradiated counterpart, display the anticipated F-actin depolymerization and severing activities...
  32. ncbi request reprint The F-actin side binding activity of the Arp2/3 complex is essential for actin nucleation and lamellipod extension
    M Bailly
    Albert Einstein College of Medicine, Department of Anatomy and Structural Biology, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Curr Biol 11:620-5. 2001
    ..This suggests that the branching activity of the Arp2/3 complex is essential for lamellipod extension, while the generation of nucleation sites for actin polymerization is not sufficient...
  33. pmc The physiological significance of beta -actin mRNA localization in determining cell polarity and directional motility
    E A Shestakova
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Proc Natl Acad Sci U S A 98:7045-50. 2001
    ..These results indicate that delocalization of beta-actin mRNA results in delocalization of nucleation sites and beta-actin protein from the leading edge followed by loss of cell polarity and directional movement...
  34. ncbi request reprint The effect of F-actin on the binding and hydrolysis of guanine nucleotide by Dictyostelium elongation factor 1A
    B T Edmonds
    Departments of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    J Biol Chem 273:10288-95. 1998
    ..eEF1A away from interactions with its known translational ligands, e.g. aminoacyl-tRNA and ribosomes...
  35. ncbi request reprint GFP expression in the mammary gland for imaging of mammary tumor cells in transgenic mice
    Fayyaz Ahmed
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Cancer Res 62:7166-9. 2002
    ..These animals provide a range of expression of GFP that is suitable for analysis of transgenic mammary tumors and metastases in vivo at the single cell level of resolution...
  36. pmc The structure of nonvertebrate actin: implications for the ATP hydrolytic mechanism
    S Vorobiev
    Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Proc Natl Acad Sci U S A 100:5760-5. 2003
    ..The conservation of functionalities involved in nucleotide binding and catalysis also provide insights into the mechanistic features of members of the family of actin-related proteins...
  37. ncbi request reprint Isolation of an abundant 50,000-dalton actin filament bundling protein from Dictyostelium amoebae
    M Demma
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York 10461
    J Biol Chem 265:2286-91. 1990
    ..The molar ratio of ABP-50 to actin is approximately 1:5 in vivo. Therefore, the abundance of ABP-50 suggests that it may be responsible for the majority of the bundling activity in these cells...
  38. pmc Mechanisms and cellular roles of local protein synthesis in mammalian cells
    Alexis J Rodriguez
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, United States
    Curr Opin Cell Biol 20:144-9. 2008
    ..Identifying regulatory sites on transport factors as well as novel physiological functions for well-known translation factors has provided significant advances in how spatially controlled translation impacts cell function...
  39. pmc Molecular cloning of hMena (ENAH) and its splice variant hMena+11a: epidermal growth factor increases their expression and stimulates hMena+11a phosphorylation in breast cancer cell lines
    Francesca Di Modugno
    Experimental Chemotherapy, Regina Elena Cancer Institute, Rome, Italy
    Cancer Res 67:2657-65. 2007
    ..The present data provide new insight into the relevance of actin cytoskeleton regulatory proteins and, in particular, of hMena isoforms in coupling multiple signaling pathways involved in breast cancer...

Research Grants59

  1. MICROENVIRONMENTS OF INVASION IN HUMAN BREAST TUMORS
    John Condeelis; Fiscal Year: 2009
    ..The specific aims of the proposal are: 1. Identify microenvironments involved in invasion in human breast tumors. 2. Determine gene expression profiles of invasive cells in human breast tumors. ..
  2. SIGNAL TRANSDUCTION AND ACTIN DURING AMOEBOID CHEMOTAXIS
    John Condeelis; Fiscal Year: 2000
    ..This analysis is predicted to allow a complete description of the molecular interactions required for the actin polymerization transients seen in a variety of cells during hormones stimulation. ..
  3. SPATIAL CONTROL OF PATHWAYS MEDIATING ACTIN DYNAMICS
    John Condeelis; Fiscal Year: 2003
    ..These reagents will be used in a variety of ways in cells to define the importance of the above mechanisms and their interactions in vivo. ..
  4. Digital Imaging System for Use in Multi-User Facility
    John Condeelis; Fiscal Year: 2002
    ..All projects require the capability to image cells or in vitro assay systems at high spatial resolution with minimum exposure to light or at high speeds. ..
  5. EF1ALPHA ACTIN IN CELL MOTILITY AND TRANSLATION
    John Condeelis; Fiscal Year: 2003
    ..mRNAs for beta-actin and Arp3, when localized to the leading edge, determine cell polarity. 2. The EF1a-F-actin complex is the scaffold to which mRNAs, with a beta-actin mRNA-like zipcode, become anchored. ..
  6. NOVEL IMAGING METHODS FOR GENE DISCOVERY IN CANCER
    John Condeelis; Fiscal Year: 2004
    ..4. Evaluate a variety of clustering algorithms, with DNA expression patterns obtained in specific aims 2 and 3, to identify genes related to cell behaviors believed necessary for metastasis. ..
  7. SIGNAL TRANSDUCTION & ACTIN DURING AMOEBOID CHEMOTAXIS
    John Condeelis; Fiscal Year: 2004
    ..Use the reagents in 1 and 2 in vivo to determine the relationships between cofilin and the Arp2/3 complex in the regulation of actin nucleation in unstimulated and EGF-stimulated cells ..
  8. Novel Methods for Detecting Cell Interactions in the Tumor Microenvironment
    John Condeelis; Fiscal Year: 2007
    ..This uses nanotechnology to miniaturize an artificial blood vessel that can in dwell in human tumor xenografts and ultimately in human tumors that can report on the status of cell collection and diagnose invasive tumors. ..
  9. Motility and Invasion
    John Condeelis; Fiscal Year: 2007
    ..This program represents a unique perspective on invasion and metastasis that has the potential for generating broad new insights into the microenvironments of the primary tumor. ..
  10. SIGNAL TRANSDUCTION & ACTIN DURING AMOEBOID CHEMOTAXIS
    John Condeelis; Fiscal Year: 2007
    ..abstract_text> ..
  11. MICROENVIRONMENTS OF INVASION IN HUMAN BREAST TUMORS
    John Condeelis; Fiscal Year: 2007
    ..The specific aims of the proposal are: 1. Identify microenvironments involved in invasion in human breast tumors. 2. Determine gene expression profiles of invasive cells in human breast tumors. ..
  12. Flourescent Lifetime Imaging Microscopy (FLIM)
    John Condeelis; Fiscal Year: 2005
    ..As discussed in the budget justification, the system we request will solve the problems of speed, sensitivity, and quantitation for an expert user group. ..
  13. INTERACTIONS OF ACTIN CYTOSKELETON WITH PLASMA MEMBRANE
    John Condeelis; Fiscal Year: 1980
    ..Nearest neighbor analysis using bifunctional reagents will be used to identify components on the vesicle membrane to which actin binds. ..
  14. SIGNAL TRANSDUCTION & ACTIN DURING AMOEBOID CHEMOTAXIS
    John Condeelis; Fiscal Year: 1992
    ..This investigation will include experiments using drugs and antibodies to modulate in vitro activity and eventual isolation of the ligand stimulated nucleation activity for actin polymerization...
  15. SIGNAL TRANSDUCTION AND ACTIN DURING AMOEBOID CHEMOTAXIS
    John Condeelis; Fiscal Year: 1993
    ..The combined approaches of protein chemistry, bacterial expression and molecular genetics in Dictyostelium will provide a definitive analysis of the structure and function of aginactin...
  16. INTERACTIONS OF ACTIN CYTOSKELETON WITH PLASMA MEMBRANE
    John Condeelis; Fiscal Year: 1993
    ....
  17. INTERACTIONS OF ACTIN CYTOSKELETON WITH PLASMA MEMBRANE
    John Condeelis; Fiscal Year: 1991
    ....