Violeta Chitu

Summary

Affiliation: Albert Einstein College of Medicine
Country: USA

Publications

  1. pmc Primed innate immunity leads to autoinflammatory disease in PSTPIP2-deficient cmo mice
    Violeta Chitu
    Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Blood 114:2497-505. 2009
  2. pmc PSTPIP2 deficiency in mice causes osteopenia and increased differentiation of multipotent myeloid precursors into osteoclasts
    Violeta Chitu
    Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Blood 120:3126-35. 2012
  3. pmc The PCH family member MAYP/PSTPIP2 directly regulates F-actin bundling and enhances filopodia formation and motility in macrophages
    Violeta Chitu
    Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Mol Biol Cell 16:2947-59. 2005
  4. doi request reprint Measurement of macrophage growth and differentiation
    Violeta Chitu
    Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York, USA
    Curr Protoc Immunol . 2011
  5. pmc Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells
    Suwen Wei
    Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    J Leukoc Biol 88:495-505. 2010
  6. ncbi request reprint Colony-stimulating factor-1 in immunity and inflammation
    Violeta Chitu
    Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York, NY 10461, USA
    Curr Opin Immunol 18:39-48. 2006
  7. ncbi request reprint Pombe Cdc15 homology (PCH) proteins: coordinators of membrane-cytoskeletal interactions
    Violeta Chitu
    Department of Developmental Biology and Molecular Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York, NY 10461, USA
    Trends Cell Biol 17:145-56. 2007
  8. pmc Fes tyrosine kinase expression in the tumor niche correlates with enhanced tumor growth, angiogenesis, circulating tumor cells, metastasis, and infiltrating macrophages
    Shengnan Zhang
    Division of Cancer Biology and Genetics, Department of Pathology and Molecular Medicine, Queen s Cancer Research Institute, Queen s University, Kingston, Ontario, Canada
    Cancer Res 71:1465-73. 2011

Collaborators

Detail Information

Publications8

  1. pmc Primed innate immunity leads to autoinflammatory disease in PSTPIP2-deficient cmo mice
    Violeta Chitu
    Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Blood 114:2497-505. 2009
    ....
  2. pmc PSTPIP2 deficiency in mice causes osteopenia and increased differentiation of multipotent myeloid precursors into osteoclasts
    Violeta Chitu
    Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Blood 120:3126-35. 2012
    ..Thus, PSTPIP2 acts as a negative feedback regulator of CSF-1R signaling to suppress inflammation and osteoclastogenesis...
  3. pmc The PCH family member MAYP/PSTPIP2 directly regulates F-actin bundling and enhances filopodia formation and motility in macrophages
    Violeta Chitu
    Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Mol Biol Cell 16:2947-59. 2005
    ..Because filopodia are postulated to increase directional motility by acting as environmental sensors, the MAYP-stimulated increase in directional movement may be at least partly explained by enhancement of filopodia formation...
  4. doi request reprint Measurement of macrophage growth and differentiation
    Violeta Chitu
    Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York, USA
    Curr Protoc Immunol . 2011
    ..It also describes methods for characterization of macrophage differentiation through the immunofluorescence analysis of cell-surface expression of CSF-1 receptor...
  5. pmc Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells
    Suwen Wei
    Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    J Leukoc Biol 88:495-505. 2010
    ..Thus, the different spatiotemporal expression of IL-34 and CSF-1 allows for complementary activation of the CSF-1R in developing and adult tissues...
  6. ncbi request reprint Colony-stimulating factor-1 in immunity and inflammation
    Violeta Chitu
    Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York, NY 10461, USA
    Curr Opin Immunol 18:39-48. 2006
    ..In several conditions, activation of macrophages involves a CSF-1 autocrine loop. In addition, secreted and cell-surface isoforms of CSF-1 can have differential effects in inflammation and immunity...
  7. ncbi request reprint Pombe Cdc15 homology (PCH) proteins: coordinators of membrane-cytoskeletal interactions
    Violeta Chitu
    Department of Developmental Biology and Molecular Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York, NY 10461, USA
    Trends Cell Biol 17:145-56. 2007
    ..Here, we review the nature, actions and disease associations of the vertebrate PCH family members, highlighting their fundamental roles in the regulation of processes involving membrane-cytoskeletal interactions...
  8. pmc Fes tyrosine kinase expression in the tumor niche correlates with enhanced tumor growth, angiogenesis, circulating tumor cells, metastasis, and infiltrating macrophages
    Shengnan Zhang
    Division of Cancer Biology and Genetics, Department of Pathology and Molecular Medicine, Queen s Cancer Research Institute, Queen s University, Kingston, Ontario, Canada
    Cancer Res 71:1465-73. 2011
    ..Taken together, our observations argue that Fes inhibition might provide therapeutic benefits in breast cancer, in part by attenuating tumor-associated angiogenesis and the metastasis-promoting functions of tumor-associated macrophages...