Richard Chahwan

Summary

Affiliation: Albert Einstein College of Medicine
Country: USA

Publications

  1. doi request reprint Crosstalk between genetic and epigenetic information through cytosine deamination
    Richard Chahwan
    Department of Cell Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Trends Genet 26:443-8. 2010
  2. ncbi request reprint The multidimensional nature of epigenetic information and its role in disease
    Richard Chahwan
    Department of Cell Biology, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, New York 10461, USA
    Discov Med 11:233-43. 2011
  3. pmc Mammalian Exo1 encodes both structural and catalytic functions that play distinct roles in essential biological processes
    Sonja Schaetzlein
    Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Proc Natl Acad Sci U S A 110:E2470-9. 2013
  4. pmc Overlapping hotspots in CDRs are critical sites for V region diversification
    Lirong Wei
    Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461
    Proc Natl Acad Sci U S A 112:E728-37. 2015
  5. pmc AIDing antibody diversity by error-prone mismatch repair
    Richard Chahwan
    Department of Cell Biology, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY 10461, USA
    Semin Immunol 24:293-300. 2012

Collaborators

  • Lirong Wei
  • Matthew D Scharff
  • Sonja Schaetzlein
  • XiaoHua Wang
  • Shanzhi Wang
  • Phuong T Pham
  • Thomas MacCarthy
  • Myron F Goodman
  • Aviv Bergman
  • Alan B Clark
  • Thomas A Kunkel
  • Kaichun Wei
  • Elena Avdievich
  • Robert L Eoff
  • Sergio Roa
  • Winfried Edelmann
  • Rani S Sellers

Detail Information

Publications5

  1. doi request reprint Crosstalk between genetic and epigenetic information through cytosine deamination
    Richard Chahwan
    Department of Cell Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Trends Genet 26:443-8. 2010
    ..We therefore propose that the AID/APOBEC family of deaminases are likely to have acted as drivers throughout vertebrate evolution...
  2. ncbi request reprint The multidimensional nature of epigenetic information and its role in disease
    Richard Chahwan
    Department of Cell Biology, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, New York 10461, USA
    Discov Med 11:233-43. 2011
    ..We hence believe that the fast development of genome-wide technologies will facilitate a better understanding of both genetic and epigenetic dimensions of disease...
  3. pmc Mammalian Exo1 encodes both structural and catalytic functions that play distinct roles in essential biological processes
    Sonja Schaetzlein
    Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Proc Natl Acad Sci U S A 110:E2470-9. 2013
    ..The separation of these functions demonstrates the differential requirement for the structural function and nuclease activity of mammalian EXO1 in distinct DNA repair processes and tumorigenesis in vivo. ..
  4. pmc Overlapping hotspots in CDRs are critical sites for V region diversification
    Lirong Wei
    Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461
    Proc Natl Acad Sci U S A 112:E728-37. 2015
    ..Our analysis suggests that the local sequence environment of the V region, and especially of the CDR1 and CDR2, is highly evolved to recruit mutations to key residues in the CDRs of the IgV region. ..
  5. pmc AIDing antibody diversity by error-prone mismatch repair
    Richard Chahwan
    Department of Cell Biology, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY 10461, USA
    Semin Immunol 24:293-300. 2012
    ....