A Casadevall


Affiliation: Albert Einstein College of Medicine
Country: USA


  1. Casadevall A, Pirofski L. Exploiting the redundancy in the immune system: vaccines can mediate protection by eliciting 'unnatural' immunity. J Exp Med. 2003;197:1401-4 pubmed
  2. request reprint
    Casadevall A. Antibodies for defense against biological attack. Nat Biotechnol. 2002;20:114 pubmed
  3. Casadevall A. Antibody-mediated immunity against intracellular pathogens: two-dimensional thinking comes full circle. Infect Immun. 2003;71:4225-8 pubmed
  4. request reprint
    Casadevall A, Pirofski L. Polysaccharide-containing conjugate vaccines for fungal diseases. Trends Mol Med. 2006;12:6-9 pubmed
    ..The description of a vaccine that could protect against various fungal pathogens opens exciting new dimensions in the search for approaches to control fungal diseases. ..
  5. Casadevall A, Relman D. Microbial threat lists: obstacles in the quest for biosecurity?. Nat Rev Microbiol. 2010;8:149-54 pubmed publisher
  6. request reprint
    Casadevall A, Feldmesser M, Pirofski L. Induced humoral immunity and vaccination against major human fungal pathogens. Curr Opin Microbiol. 2002;5:386-91 pubmed
    ..Protective monoclonal antibodies can be used to identify antigens that induce useful humoral responses. ..
  7. request reprint
    Casadevall A, Pirofski L. Insights into mechanisms of antibody-mediated immunity from studies with Cryptococcus neoformans. Curr Mol Med. 2005;5:421-33 pubmed
    ..Observations with C. neoformans have stimulated a reappraisal of the role of humoral immunity for other pathogens and highlighted the limitations in current methods of assessing the role of Ab in host defense. ..
  8. Casadevall A, Pirofski L. Antibody-mediated protection through cross-reactivity introduces a fungal heresy into immunological dogma. Infect Immun. 2007;75:5074-8 pubmed
  9. Casadevall A. Evolution of intracellular pathogens. Annu Rev Microbiol. 2008;62:19-33 pubmed publisher
    ..Although often viewed as a specialized adaptation, the capacity for intracellular survival may be widespread among microbes, thus questioning whether the intracellular lifestyle warrants a category of special distinctiveness. ..

More Information


  1. Casadevall A, Nosanchuk J, Williamson P, Rodrigues M. Vesicular transport across the fungal cell wall. Trends Microbiol. 2009;17:158-62 pubmed publisher
    ..The discovery of vesicular transport in fungi opens many new avenues for investigation in basic cell biology and pathogenesis. ..