Research Topics
| Harvey BabichSummaryAffiliation: Albert Einstein College of Medicine Country: USA Publications
| Collaborators
|
Detail Information
Publications
Cranberry juice extract, a mild prooxidant with cytotoxic properties independent of reactive oxygen speciesH Babich
Department of Biology, Stern College for Women, 245 Lexington Avenue, New York, NY 10016, USA
Phytother Res 26:1358-65. 2012..These differences in toxicity between SOD-stabilized CJE, freshly prepared CJE, and 'spent' CJE were confirmed in HSC-2 cells stained with aceto-orcein, which also indicated that the mode of cell death was by the induction of apoptosis...- Gingko biloba leaf extract induces oxidative stress in carcinoma HSC-2 cellsHarvey Babich
Department of Biology, Stern College for Women, Yeshiva University, New York, NY 10016, USA
Toxicol In Vitro 23:992-9. 2009..biloba extract was noted by apoptotic cell morphologies, by TUNEL staining, and by PARP cleavage. The data strongly suggest that the prooxidative nature of the G. biloba extract was the cause of apoptotic cell death... - Choice of DMEM, formulated with or without pyruvate, plays an important role in assessing the in vitro cytotoxicity of oxidants and prooxidant nutraceuticalsH Babich
Department of Biology, Stern College for Women, Yeshiva University, 245 Lexington Avenue, New York, NY 10016, USA
In Vitro Cell Dev Biol Anim 45:226-33. 2009..This study suggested that the pyruvate status of Dulbecco's modified Eagle's medium be specified in the experimental design, especially in studies involving oxidative stress... - Theaflavin-3-gallate and theaflavin-3'-gallate, polyphenols in black tea with prooxidant propertiesHarvey Babich
Department of Biology, Stern College for Women, Yeshiva University, New York, NY, USA
Basic Clin Pharmacol Toxicol 103:66-74. 2008..These studies demonstrated that the black tea theaflavin monomers, TF-2A and TF-2B, act as prooxidants and induce oxidative stress, with carcinoma cells more sensitive than normal fibroblasts... - In vitro cytotoxicity of (-)-catechin gallate, a minor polyphenol in green teaH Babich
Stern College for Women, Yeshiva University, Department of Biology, 245 Lexington Avenue, NY 10016, USA
Toxicol Lett 171:171-80. 2007..The overall cytotoxicity of CG was similar to its epimer, ECG and both exhibited antiproliferative effects equivalent to, or stronger than, EGCG, the most abundant catechin in green tea... - In vitro cytotoxicity of a theaflavin mixture from black tea to malignant, immortalized, and normal cells from the human oral cavityH Babich
Department of Biology, Stern College for Women, Yeshiva University, 245 Lexington Avenue, New York, NY 10016, USA
Toxicol In Vitro 20:677-88. 2006..For both cell types, coexposures of the theaflavin mixture with catalase or CoCl(2) afforded protection... - Differential in vitro cytotoxicity of (-)-epicatechin gallate (ECG) to cancer and normal cells from the human oral cavityH Babich
Department of Biology, Stern College for Women, Yeshiva University, 245 Lexington Avenue, New York, NY 10016, USA
Toxicol In Vitro 19:231-42. 2005..ECG induced apoptosis in the carcinoma HSC-2 cells, but not in the normal HGF-2 fibroblasts. This research supports those studies suggesting that tea green is an effective chemopreventive agent of oral carcinoma... - Mediation of the in vitro cytotoxicity of green and black tea polyphenols by cobalt chlorideH Babich
Department of Biology, Stern College for Women, Yeshiva University, 245 Lexington Avenue, New York, NY 10016, USA
Toxicol Lett 155:195-205. 2005.... - Theaflavin-3,3'-digallate, a component of black tea: an inducer of oxidative stress and apoptosisAlyssa G Schuck
Department of Biology, Stern College for Women, Yeshiva University, 245 Lexington Avenue, New York, NY 10016, USA
Toxicol In Vitro 22:598-609. 2008..Apoptosis was not noted in GN46 fibroblasts treated with TF-3... - Pomegranate extract, a prooxidant with antiproliferative and proapoptotic activities preferentially towards carcinoma cellsJeffrey H Weisburg
Department of Biology, Stern College for Women, Yeshiva University, 245 Lexington Avenue, New York, NY 10016, USA
Anticancer Agents Med Chem 10:634-44. 2010..Lessening of caspase-3 activation and of PARP cleavage in cells co-treated with PE and either cobalt or pyruvate, respectively, as compared to PE alone, indicated that apoptosis was through the prooxidant nature of PE... - In vitro cytotoxicity of epigallocatechin gallate and tea extracts to cancerous and normal cells from the human oral cavityJeffrey H Weisburg
Stern College for Women, Yeshiva University, Department of Biology, 245 Lexington Avenue, New York, NY 10016, U S A
Basic Clin Pharmacol Toxicol 95:191-200. 2004..The results presented herein are consistent with EGCG acting as a prooxidant, with the cancerous cells more sensitive to oxidative stress than the normal cells... - In vitro cytotoxicity of protocatechuic acid to cultured human cells from oral tissue: involvement in oxidative stressHarvey Babich
Stern College for Women, Yeshiva University, Department of Biology, 245 Lexington Avenue, New York, NY 10016, USA
Pharmacol Toxicol 91:245-53. 2002..5 mM) enhanced their sensitivity to a subsequent exposure to tert-butyl hydroperoxide. These findings were consistent with protocatechuic acid, at high levels (> or = 10 mM), acting as an inducer of oxidative stress... - In vitro cytotoxicity of the nitric oxide donor, S-nitroso-N-acetyl-penicillamine, towards cells from human oral tissueH Babich
Department of Biology, Stern College for Women, Yeshiva University, New York, New York 10016, USA
Pharmacol Toxicol 84:218-25. 1999..Cells exposed to SNAP exhibited nuclear aberrations, including multilobed nuclei and multinucleation. SNAP-induced cell death was apparently by apoptosis, as noted by fluorescence microscopy and DNA agarose gel electrophoresis... - In vitro response of human gingival epithelial S-G cells to resveratrolH Babich
Stern College for Women, Yeshiva University, Department of Biology, 245 Lexington Avenue, New York, NY 10016, USA
Toxicol Lett 114:143-53. 2000..For nitric oxide, only N-acetyl-L-cysteine reduced toxicity. The ability of resveratrol to function as an antioxidant was, therefore, not noted under these test conditions... - Indirect cytotoxicity of dental materials: a study with Transwell inserts and the neutral red uptake assayH Babich
Department of Biology, Stern College for Women, Yeshiva University, 245 Lexington Avenue, New York, NY 10016, USA
Altern Lab Anim 29:9-13. 2001..The sequence of cytotoxicity of the dental restoratives to the S-G cells was Vitremer > Ketac-Molar Aplicap > Flow-It... - In vitro cytotoxicity of glyco-S-nitrosothiols. a novel class of nitric oxide donorsH Babich
Department of Biology, Stern College for Women, Yeshiva University, 245 Lexington Avenue, New York 10016, New York, USA
Toxicol In Vitro 15:181-90. 2001..In comparison with other classes of NO donors the sequence of toxicity towards S-G cells was S-nitrosoglutathione>glucose-SNAPs>SNAP, sodium nitroprusside>spermine NONOate>DPTA NONOate>DETA NONOate>fructose-1-SNAP>>SIN-1... - In vitro response of human gingival epithelioid S-G cells to minocyclineH Babich
Department of Biology, Stern College for Women, Yeshiva University, 245 Lexington Avenue, New York, NY 10016, USA
Toxicol In Vitro 16:11-21. 2002.... - In vitro cytotoxicity to human cells in culture of some phenolics from olive oilH Babich
Department of Biology, Stern College for Women, Yeshiva University, 245 Lexington Avenue, New York, NY 10016, USA
Farmaco 58:403-7. 2003..Cytotoxicity was noted only at phenolic concentrations far exceeding those attainable after habitual consumption, thus indicating that consumption of phenol-rich olive oil is safe... - Sodium lauryl sulfate and triclosan: in vitro cytotoxicity studies with gingival cellsH Babich
Stern College for Women, Yeshiva University, Department of Biology, New York, NY 10016, USA
Toxicol Lett 91:189-96. 1997..Pretreatment with triclosan potentiated the toxicity of a subsequent exposure of SLS to the S-G cells; a similar pretreatment of the GF fibroblasts with triclosan had no effect on a subsequent challenge with SLS... - Research strategies in the study of the pro-oxidant nature of polyphenol nutraceuticalsHarvey Babich
Department of Biology, Stern College for Women, Yeshiva University, 245 Lexington Avenue, New York, NY 10016, USA
J Toxicol 2011:467305. 2011..Attention also must be directed to the influence of iron and copper ions and to the level of polyphenols, which mediate oxidative stress...