Research Topics
| Howard S SmithSummaryAffiliation: Albany Medical College Country: USA Publications
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Detail Information
Publications
Perioperative intravenous acetaminophen and NSAIDsHoward S Smith
Department of Anesthesiology, Albany Medical College, Albany, New York 12208, USA
Pain Med 12:961-81. 2011..g., earlier ambulation and discharge)...
Loin pain hematuria syndrome-visceral or neuropathic pain syndrome?Howard S Smith
Department of Anesthesiology, Albany Medical College, NY 12208, USA
Clin J Pain 28:646-51. 2012..A brief review of LPHS potential pathophysiology and potential treatment approaches is presented...
Opioids and neuropathic painHoward S Smith
Albany Medical College, Department of Anesthesiology, 47 New Scotland Avenue MC 131 Albany, New York 12208, USA
Pain Physician 15:ES93-110. 2012....
Treatment considerations in painful HIV-related neuropathyHoward S Smith
Albany Medical College, Department of Anesthesiology, Albany, NY, USA
Pain Physician 14:E505-24. 2011..The risk benefit ratio of treatment with agents such as NRTIs as well as opioids should be reviewed for specific individual patients, prior to clinicians initiating these agents...
A comprehensive review of rapid-onset opioids for breakthrough painHoward Smith
Departments of Anesthesiology, Medicine, and Physical Medicine and Rehabilitation, Albany Medical College, Albany, NY 12208, USA
CNS Drugs 26:509-35. 2012..The findings of this review suggest that the efficacy and safety of the approved rapid-onset opioids are comparable...
Pharmacokinetics of intravenous ibuprofen: implications of time of infusion in the treatment of pain and feverHoward S Smith
Department of Anesthesiology, Albany Medical Center, Albany, NY 12208, USA
Drugs 72:327-37. 2012....
Gout: current insights and future perspectivesHoward S Smith
Albany Medical College, Department of Anesthesiology, Albany, New York 12208, USA
J Pain 12:1113-29. 2011..PERSPECTIVE: Gout is an underappreciated and extremely painful condition. Over the last 2 years new thought on pathophysiology of gout taking into account the inflammasome and new therapeutic agents have changed management strategies...
Explosive growth of facet joint interventions in the Medicare population in the United States: a comparative evaluation of 1997, 2002, and 2006 dataLaxmaiah Manchikanti
Pain Management Center of Paducah, 2831 Lone Oak Road, Paducah, KY, 42003, USA
BMC Health Serv Res 10:84. 2010..The purpose of the study was to determine trends of frequency and cost of facet joint interventions in managing spinal pain...
Potential analgesic mechanisms of acetaminophenHoward S Smith
Albany Medical College, Albany, NY 12208, USA
Pain Physician 12:269-80. 2009..A greater understanding of APAP's analgesic mechanisms may promote optimal utilization of analgesic polypharmacy...
Systematic review of the role of sedation in diagnostic spinal interventional techniquesHoward S Smith
Albany Medical College, Albany, NY 12208, USA
Pain Physician 12:195-206. 2009..Further, there is no consensus with regards to sedation prior to controlled diagnostic blocks and their influence on the accuracy and validity of a diagnosis...
Intrathecal drug deliveryHoward S Smith
Department of Anesthesiology, Albany Medical College, Albany, NY 12208, USA
Pain Physician 11:S89-S104. 2008..Further clinical studies are needed to evaluate the efficacy and safety of new intrathecal drugs, the complications related to these devices, and the proper selection of patients to receive these treatments...
Documentation and potential tools in long-term opioid therapy for painHoward S Smith
Albany Medical College, Department of Anesthesiology, 47 New Scotland Avenue, MC 131 Albany, New York 12208, USA
Anesthesiol Clin 25:809-23, vii. 2007..Several potential tools and documentation strategies are discussed that will aid clinicians in providing evidence for the continuation of this type of treatment for their patients...
Opioid metabolismHoward S Smith
Department of Anesthesiology, Albany Medical College, Albany, NY 12208, USA
Mayo Clin Proc 84:613-24. 2009..Articles selected for inclusion discussed general physiologic aspects of opioid metabolism, metabolic characteristics of specific opioids, patient-specific factors influencing drug metabolism, drug interactions, and adverse events...
Calcineurin as a nociceptor modulatorHoward S Smith
Albany Medical College, Department of Anesthesiology, Albany, NY 12208, USA
Pain Physician 12:E309-18. 2009..A greater understanding of the physiology of calcineurin, especially as it relates to modulating nociception may lead to the development of novel analgesic targets in attempts to optimally alleviate patient discomfort...
Fibromyalgia syndrome: a discussion of the syndrome and pharmacotherapyHoward S Smith
Albany Medical College, Department of Anesthesiology, Albany, NY 12208, USA
Am J Ther 17:418-39. 2010....
Hydrogen sulfide's involvement in modulating nociceptionHoward S Smith
Albany Medical College, Department of Anesthesiology, Albany, NY 12208, USA
Pain Physician 12:901-10. 2009..A greater understanding of the clinically significant human physiology of H2S and hydrogen sulfide's effects on modulating nociceptive processes may potentially lead to novel targets for improving analgesia...
Activated microglia in nociceptionHoward S Smith
Albany Medical College, Department of Anesthesiology, Albany, NY 12208, USA
Pain Physician 13:295-304. 2010..A greater appreciation of the roles of various mediators/paths which activate microglia might help lead to future novel therapeutic targets in efforts to ameliorate severe symptoms of neuropathic pain...
The role of genomic oxidative-reductive balance as predictor of complex regional pain syndrome development: a novel theoryHoward S Smith
Albany Medical College, Department of Anesthesiology, Albany, NY 12208, USA
Pain Physician 13:79-90. 2010..Furthermore, it could lead to the development of novel prevention or intervention strategies, in efforts to prevent, abort, or ameliorate the development of and/or effectively treat complex regional pain syndrome...
Peripherally-acting opioidsHoward S Smith
Department of Anesthesiology, Albany Medical College, Albany, NY 12208, USA
Pain Physician 11:S121-32. 2008..Peripherally-acting opioids, which capitalize on peripheral endogenous opioid analgesic systems, may be one potential future strategy which may be utilized in efforts to achieve potent analgesia with minimal side effects...
Painful hidradenitis suppurativaHoward S Smith
Department of Anesthesiology, Academic Director of Pain Management, Albany Medical College, Albany, NY 12208, USA
Clin J Pain 26:435-44. 2010..A greater understanding of the diagnosis, pathophysiology, and potential treatment options for HS patients may help providers to be better able to contribute to care of patients with painful hidradenitis suppurativa...
Proton pump inhibitors and painHoward S Smith
Albany Medical College, Department of Anesthesiology, Albany, NY 12208, USA
Pain Physician 12:1013-23. 2009..While there is no robust direct evidence to support any associations of PPIs and iron deficiency or PPIs associated with RLS-like symptoms (including RLSAP), it is hoped that this manuscript may spark research efforts on this issue...
Painful osseous metastasesHoward S Smith
Albany Medical College, Department of Anesthesiology, 47 New Scotland Avenue, MC 131, Albany, New York 12208, USA
Pain Physician 14:E373-403. 2011..Additionally, potential future therapeutic approaches to painful osseous metastases may revolutionize approaches to analgesia for this condition, leading to optimal outcomes with maximal pain relief and minimal adverse effects...
Documentation and potential tools in long-term opioid therapy for painHoward S Smith
Albany Medical College, Department of Anesthesiology, 47 New Scotland Avenue, MC 131 Albany, New York 12208, USA
Med Clin North Am 91:213-28. 2007..Several potential tools and documentation strategies re discussed that will aid clinicians in providing evidence for the continuation of this type of treatment for their patients...
The metabolism of opioid agents and the clinical impact of their active metabolitesHoward S Smith
Department of Anesthesiology, Albany Medical College, Albany, NY 12208, USA
Clin J Pain 27:824-38. 2011....
Morphine sulfate and naltrexone hydrochloride extended release capsules for the management of chronic, moderate-to-severe pain, while reducing morphine-induced subjective effects upon tampering by crushingHoward S Smith
Pain Management Center, Albany Medical College, Department of Anesthesiology, Albany, NY 12208, USA
Expert Opin Pharmacother 12:1111-25. 2011..Epidemiological studies are required to determine the impact of such products on real-world abuse...
Pharmacological treatment of diabetic neuropathic painHoward S Smith
Albany Medical College, Department of Anesthesiology, Albany, New York 12208, USA
Drugs 71:557-89. 2011..It is hoped that in the future clinicians will be able to assess patient pathophysiology, which may help them to match optimal therapeutic agents to target individual patient aberrant mechanisms...
Combination opioid analgesicsHoward S Smith
Department of Anesthesiology, Albany Medical College, Albany, NY 12208, USA
Pain Physician 11:201-14. 2008..Combination opioid analgesics are one avenue which may give rise to "pain pills" with improved analgesic profiles over existing analgesic medications...
Variations in opioid responsivenessHoward S Smith
Department of Anesthesiology, Albany Medical College, Albany, NY 12208, USA
Pain Physician 11:237-48. 2008..In the future, armed with data of this type, clinicians may become quite adept at tailoring appropriate opioid therapy as well as optimal opioid rotation strategies...
Fibromyalgia: an afferent processing disorder leading to a complex pain generalized syndromeHoward S Smith
Albany Medical College, Department of Anesthesiology, Albany, NY 12208, USA
Pain Physician 14:E217-45. 2011..g., duloxetine, milnacipran] and alpha 2-delta receptor ligands [e.g., pregabalin]) might improve symptoms as well as function in patients with fibromyalgia...
Personalized pharmacotherapy for treatment approaches focused at primary insomniaHoward S Smith
Albany Medical College, Department of Anesthesiology, NY, USA
Am J Ther 18:227-40. 2011....
Chronic opioid therapy issues associated with opioid abuse potentialHoward S Smith
Albany Medical College, Department of Anesthesiology, Albany, New York, USA
J Opioid Manag 5:287-300. 2009..Finally, discussion is presented regarding what practices seen in opioid prescribing can be considered "in-or-out" of the mainstream box...
Applying partially occluded fentanyl transdermal patches to manage pain in pediatric patientsAmy Mitchell
Albany Medical Center, New York, USA
J Opioid Manag 6:290-4. 2010..A technique of using a partially occluded FTP is presented in an effort to encourage further study of this and perhaps other techniques...
Pain responsiveness to opioids: central versus peripheral neuropathic painHoward S Smith
Department of Anesthesiology, Albany Medical College, New York, USA
J Opioid Manag 7:391-400. 2011....
Oral administration of (131)I by semiautomatic pipette to a patient with severe swallowing difficulties: a case reportMaroun Karam
Nuclear Medicine Section, Radiology Department, Albany Medical College, Albany, New York 12208, USA
J Nucl Med Technol 31:161-2. 2003..In patients with swallowing difficulties, use of the pipette constitutes a safe and efficient means to deliver (131)I-sodium iodide by the oral route...
Arachidonic acid pathways in nociceptionHoward S Smith
Department of Anesthesiology, Albany Medical College, Albany, New York, USA
J Support Oncol 4:277-87. 2006....
Myofascial trigger pointsElizabeth Demers Lavelle
Department of Anesthesiology, Albany Medical Center, 43 New Scotland Avenue, Albany, NY 12208, USA
Anesthesiol Clin 25:841-51, vii-iii. 2007..The etiology, pathophysiology, and treatment of myofascial trigger points are addressed in this article...
Review article: palliative care in gynecologic oncologyYoussef Rezk
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Albany Medical College, Albany, NY 12208, USA
Am J Hosp Palliat Care 28:356-74. 2011..There remains a real need for more emphasis on palliative care education in training programs...
Pharmacotherapy for fibromyalgiaHoward S Smith
Department of Anesthesiology, Albany Medical College Albany, NY, USA
Front Pharmacol 2:17. 2011..Finally a clinical algorithm will be presented for the step-wise management of pain and other associated symptoms of FM...
Overview of pain management in older personsGlenn Deane
Department of Sociology, University at Albany, State University of New York, Albany, NY 12222, USA
Clin Geriatr Med 24:185-201, v. 2008..It also describes treatment options that are both available and acceptable to older adults...
Analgesic prescribing errors and associated medication characteristicsHoward S Smith
Department of Anesthesiology, Albany Medical Center, 43 New Scotland Avenue, Albany, NY 12208, USA
J Pain 12:29-40. 2011..The findings of this study can guide patient and caregiver education, and can be incorporated into medication safety strategies to reduce patient risk from analgesic errors...
Myofascial trigger pointsElizabeth Demers Lavelle
Department of Anesthesiology, Albany Medical Center, 43 New Scotland Avenue, Albany, NY 12208, USA
Med Clin North Am 91:229-39. 2007..The etiology, pathophysiology, and treatment of myofascial trigger points are addressed in this article...
An update of evaluation of intravenous sedation on diagnostic spinal injection proceduresHoward S Smith
Albany Medical College, Albany, NY West Virginia University Hospitals, Morgantown, WV and University of Wisconsin School of Medicine and Public Health, Madison, WI
Pain Physician 16:SE217-28. 2013..Moreover, there is no consensus with regards to the use of sedation analgesic measures prior to controlled diagnostic blocks and their influence on the accuracy and validity of a diagnosis...
Prescription opioid abuse in chronic pain: a review of opioid abuse predictors and strategies to curb opioid abuseNalini Sehgal
University of Wisconsin School of Medicine and Public Health, Department of Orthopedics and Rehabilitation, Madison, WI 53595, USA
Pain Physician 15:ES67-92. 2012....
Painful rheumatoid arthritisHoward S Smith
Albany Medical College, Department of Anesthesiology, Albany, NY 12208, USA
Pain Physician 14:E427-58. 2011..This narrative review of rheumatoid arthritis is intended to familiarize the interventional pain specialist with current concepts surrounding rheumatoid arthritis...
Meloxicam and selective COX-2 inhibitors in the management of pain in the palliative care populationHoward S Smith
UPMC Presbyterian Pain Medicine, Department of Anesthesiology, Pittsburgh, Pennsylvania, USA
Am J Hosp Palliat Care 20:297-306. 2003..New COX-2 selective agents are discussed, including valdecoxib, parecoxib, etoricoxib, and COX-189...
Safety and efficacy of intrathecal ziconotide in the management of severe chronic painHoward S Smith
Albany Medical College, Department of Anesthesiology, Albany, New York, USA
Ther Clin Risk Manag 5:521-34. 2009..With appropriate usage multiple studies have shown ziconotide to be a safe and effective intrathecal analgesic alone or in combination with other intrathecal analgesics...
Opioids for persistent noncancer painGary McCleane
Rampark Pain Centre, 2 Rampark Dromore Road, Lurgan BT66 7JH, Northern Ireland, UK
Anesthesiol Clin 25:787-807, vi-ii. 2007..Problems associated with opioids dictate that more efficacious and safer drugs need to be found...
Opioids for persistent noncancer painGary McCleane
Rampark Pain Centre, 2 Rampark Dromore Road, Lurgaqn BT66 7JH, Northern Ireland, UK
Med Clin North Am 91:177-97. 2007..This article concentrates on this "new" evidence as disclosed by recent publications...
Botulinum toxin in pain management of soft tissue syndromesHoward S Smith
University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Clin J Pain 18:S147-54. 2002..Proper patient selection, injection technique, and dosing are critical to obtaining the best outcomes in managing pain with botulinum toxin. Additional study is needed to better characterize its use for the treatment of pain...
Management of hiccups in the palliative care populationHoward S Smith
Presbyterian University Hospital, University of Pittsburgh Medical Center, Pennsylvania, USA
Am J Hosp Palliat Care 20:149-54. 2003..Baclofen seems to be a promising drug for use with both palliative care and perioperative patients, and using garabentin as an add-on to baclofen may also be a reasonable option to consider..
Interventional techniques: evidence-based practice guidelines in the management of chronic spinal painMark V Boswell
American Society of Interventional Pain Physicians, Paducah, KY 42001, USA
Pain Physician 10:7-111. 2007..The evidence-based practice guidelines for the management of chronic spinal pain with interventional techniques were developed to provide recommendations to clinicians in the United States...
Opioid-related issues "popping" up againHoward S Smith
Pain Physician 11:S1-4. 2008
Special issues and concerns in the evaluation of older adults who have painKenneth L Kirsh
Pharmacy Practice and Science, University of Kentucky, 725 Rose Street, 201B, Lexington, KY 40536 0082, USA
Clin Geriatr Med 24:263-74, vi. 2008....
Use of meperidine in patient-controlled analgesia and the development of a normeperidine toxic reactionThomas T Simopoulos
Department of Anesthesiology and Critical Care, Postoperative Pain Services, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA 02215, USA
Arch Surg 137:84-8. 2002..Intravenous patient-controlled analgesia (IV PCA) meperidine hydrochloride can be used with a reasonable margin of safety...
Epidural steroids in the management of chronic spinal pain: a systematic reviewSalahadin Abdi
University of Miami, Miller School of Medicine, Miami, FL 33136, USA
Pain Physician 10:185-212. 2007..However, there has been a lack of well-designed randomized, controlled studies to determine the effectiveness of epidural injections. Consequently, debate continues as to the value of epidural steroid injections in managing spinal pain...
