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Species | Amy L VincentSummaryAffiliation: Agricultural Research Service Country: USA Publications
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Publications
Evaluation of hemagglutinin subtype 1 swine influenza viruses from the United StatesAmy L Vincent
Virus and Prion Diseases of Livestock Research Unit, National Animal Disease Center, USDA, ARS, Ames, IA 50010, USA
Vet Microbiol 118:212-22. 2006..S. pig population exhibit considerable variability in pathogenicity. There appears to be an increase in genetic and antigenic diversity coincident with the emergence of the swine triple reassortant H3N2 in 1998...
Kinetics of Lung Lesion Development and Pro-Inflammatory Cytokine Response in Pigs With Vaccine-Associated Enhanced Respiratory Disease Induced by Challenge With Pandemic (2009) A/H1N1 Influenza VirusP C Gauger
Virus and Prion Diseases of Livestock Research Unit, National Animal Disease Center, PO Box 70, Ames, IA 50010, USA Email
Vet Pathol 49:900-12. 2012..The lung alterations and host immune response are consistent with the vaccine-associated enhanced respiratory disease (VAERD) clinical outcome observed reproducibly in this swine model...
Live attenuated influenza vaccine provides superior protection from heterologous infection in pigs with maternal antibodies without inducing vaccine-associated enhanced respiratory diseaseAmy L Vincent
Virus and Prion Research Unit, National Animal Disease Center, USDA, Agricultural Research Service, Ames, Iowa, USA
J Virol 86:10597-605. 2012..These results have implications not only for pigs but also for other influenza virus host species...- Efficacy of inactivated swine influenza virus vaccines against the 2009 A/H1N1 influenza virus in pigsAmy L Vincent
Virus and Prion Diseases of Livestock Research Unit, National Animal Disease Center, USDA ARS, 1920 Dayton Road, Ames, IA 50010, USA
Vaccine 28:2782-7. 2010..However, consideration should be given for development of monovalent homologous vaccines to best protect the swine population thus limiting shedding and the potential transmission of 2009 A/H1N1 from pigs to people... - Experimental inoculation of pigs with pandemic H1N1 2009 virus and HI cross-reactivity with contemporary swine influenza virus antiseraAmy L Vincent
Virus and Prion Diseases Research Unit, National Animal Disease Center, USDA, ARS, Ames, IA, USA
Influenza Other Respi Viruses 4:53-60. 2010..The gene constellation of the virus was a combination from swine influenza A viruses (SIV) of North American and Eurasian lineages that had never before been identified in swine or other species... - Characterization of a newly emerged genetic cluster of H1N1 and H1N2 swine influenza virus in the United StatesAmy L Vincent
Virus and Prion Diseases of Livestock Research Unit, National Animal Disease Center, USDA ARS, 2300 Dayton Road, Ames, IA 50010, USA
Virus Genes 39:176-85. 2009..This study indicates that the human-like H1 SIV can efficiently replicate and transmit in the swine host and now co-circulates with contemporary SIVs as a distinct genetic cluster of H1 SIV... - Characterization of an influenza A virus isolated from pigs during an outbreak of respiratory disease in swine and people during a county fair in the United StatesAmy L Vincent
Virus and Prion Diseases of Livestock Research Unit, National Animal Disease Center, USDA, Agricultural Research Service, Ames, IA 50010, USA
Vet Microbiol 137:51-9. 2009..The characteristics of the OH07 virus in our pig experimental model as well as the documented human transmission warrant close monitoring of the spread of this virus in pig and human populations... - Absence of 2009 pandemic H1N1 influenza A virus in fresh porkAmy L Vincent
Virus and Prion Diseases Research Unit, National Animal Disease Center, United States Department of Agriculture, Agricultural Research Service, Ames, Iowa, United States of America
PLoS ONE 4:e8367. 2009..These findings support the WHO recommendation that pork harvested from pandemic influenza A H1N1 infected swine is safe to consume when following standard meat hygiene practices... - Efficacy of intranasal administration of a truncated NS1 modified live influenza virus vaccine in swineAmy L Vincent
Virus and Prion Diseases of Livestock Research Unit, National Animal Disease Center, USDA, Agricultural Research Service, Ames, IA 50010, United States
Vaccine 25:7999-8009. 2007..However, there appeared to be substantial cross-reactivity in antibodies at the mucosal level with the CO99 virus in MLV vaccinated pigs... - Failure of protection and enhanced pneumonia with a US H1N2 swine influenza virus in pigs vaccinated with an inactivated classical swine H1N1 vaccineAmy L Vincent
Virus and Prion Diseases of Livestock Research Unit, National Animal Disease Center, USDA, Agricultural Research Service, 2300 Dayton Road, Ames, IA 50010, USA
Vet Microbiol 126:310-23. 2008..In addition, live virus infection conferred protection against heterologous challenge... - Vaccination of pigs against swine influenza viruses by using an NS1-truncated modified live-virus vaccineJürgen A Richt
Virus and Prion Diseases of Livestock Research Unit, National Animal Disease Center, USDA, Agricultural Research Service, 2300 Dayton Ave B 15, Ames, IA 50010, USA
J Virol 80:11009-18. 2006..Vaccinated pigs were seronegative for NS1, indicating the potential use of the TX98 NS1black triangle126 MLV as a vaccine to differentiate infected from vaccinated animals... - Enhanced pneumonia and disease in pigs vaccinated with an inactivated human-like (δ-cluster) H1N2 vaccine and challenged with pandemic 2009 H1N1 influenza virusPhillip C Gauger
National Animal Disease Center, USDA, Agricultural Research Service, Ames, IA 50010, USA
Vaccine 29:2712-9. 2011..Overall, these results suggest that inactivated SIV vaccines may potentiate clinical signs, inflammation and pneumonia following challenge with divergent homosubtypic viruses that do not share cross-reacting HI or SN antibodies... - Pathogenicity and transmission in pigs of the novel A(H3N2)v influenza virus isolated from humans and characterization of swine H3N2 viruses isolated in 2010-2011Pravina Kitikoon
Virus and Prion Disease Research Unit, National Animal Disease Center, USDA ARS, Ames, Iowa, USA
J Virol 86:6804-14. 2012..Continued monitoring of these H3N2 viruses is necessary to evaluate the evolution and potential loss of population immunity in swine and humans... - Identification of H2N3 influenza A viruses from swine in the United StatesWenjun Ma
Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
Proc Natl Acad Sci U S A 104:20949-54. 2007..Taken together, these findings suggest that the H2N3 virus has undergone some adaptation to the mammalian host and that their spread should be very closely monitored... - Comparison of humoral and cellular immune responses to inactivated swine influenza virus vaccine in weaned pigsRatree Platt
Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, United States
Vet Immunol Immunopathol 142:252-7. 2011..Overall, the adjuvanted UV-inactivated A/SW/MN/02011/08 H1N2 SIV vaccine stimulated both humoral and cellular immune responses including the CD4-CD8+ T cell subset... - Identification and characterization of a highly virulent triple reassortant H1N1 swine influenza virus in the United StatesWenjun Ma
Virus and Prion Diseases of Livestock Research Unit, National Animal Disease Center, USDA, Agricultural Research Service, Ames, IA 50010, USA
Virus Genes 40:28-36. 2010..The highly virulent H1N1 swine influenza virus is further evidence of reassortment among avian, human and swine influenza viruses and justifies the need for continued surveillance of influenza viruses in swine... - Swine influenza viruses a North American perspectiveAmy L Vincent
Virus and Prion Diseases of Livestock Research Unit, National Animal Disease Center, USDA ARS, Ames, Iowa 50010, USA
Adv Virus Res 72:127-54. 2008.... - Vaccination with NS1-truncated H3N2 swine influenza virus primes T cells and confers cross-protection against an H1N1 heterosubtypic challenge in pigsMatthew A Kappes
Virus and Prion Diseases Research Unit, National Animal Disease Center, USDA ARS, 1920 Dayton Ave, PO Box 70, Ames, IA 50010, USA
Vaccine 30:280-8. 2012..These results demonstrate that NS1Δ SIV vaccines can elicit cell-mediated cross-protection against antigenically divergent strains... - Intranasal vaccination with replication-defective adenovirus type 5 encoding influenza virus hemagglutinin elicits protective immunity to homologous challenge and partial protection to heterologous challenge in pigsDouglas R Braucher
Virus and Prion Research Unit, National Animal Disease Center, United States Department of Agriculture Agricultural Research Service, Ames, Iowa, USA
Clin Vaccine Immunol 19:1722-9. 2012.... - Utility of a panviral microarray for detection of swine respiratory viruses in clinical samplesTracy L Nicholson
Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, USDA, Ames, IA 50010, USA
J Clin Microbiol 49:1542-8. 2011.... - Vaccine efficacy and immune response to swine influenza virus challenge in pigs infected with porcine reproductive and respiratory syndrome virus at the time of SIV vaccinationPravina Kitikoon
Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, P O Box 3020, Iowa State University, Ames, IA 50010, USA
Vet Microbiol 139:235-44. 2009..These findings demonstrate that PRRSV infection has a significant impact on SIV vaccine efficacy that may be important for disease control... - Differences in clinical disease and immune response of pigs challenged with a high-dose versus low-dose inoculum of porcine reproductive and respiratory syndrome virusCrystal L Loving
Respiratory Diseases of Livestock Research Unit, U S Department of Agriculture, Agricultural Research Service, National Animal Disease Center, Ames, Iowa 50010, USA
Viral Immunol 21:315-25. 2008..IFN-gamma may play a role in PRRSV pathogenesis, as serum levels increased significantly in pigs challenged with the high dose of PRRSV... - Heightened adaptive immune responses following vaccination with a temperature-sensitive, live-attenuated influenza virus compared to adjuvanted, whole-inactivated virus in pigsCrystal L Loving
Virus and Prion Diseases of Livestock Research Unit, National Animal Disease Center, USDA ARS, Ames, IA, United States
Vaccine 30:5830-8. 2012..Taken together, these results indicate the ts LAIV vaccine, generated from a triple reassortant IAV, elicits greater cell-mediated and humoral immune responses in pigs... - Comparison of Human-Like H1 (δ-Cluster) Influenza A Viruses in the Swine HostJanice R Ciacci Zanella
Virus and Prion Diseases Research Unit, National Animal Disease Center, Agricultural Research Service, USDA, Ames, IA 50010, USA Labex USA, Brazilian Agriculture Research Corporation EMBRAPA, 70770 901 Brasília, DF, Brazil Embrapa Swine and Poultry Research Center, 89700 000 Concórdia, SC, Brazil
Influenza Res Treat 2012:329029. 2012..Greater serological cross-reactivity was observed for viruses from the same HA phylogenetic sub-cluster; however, antigenic differences between the sub-clusters may have implications for disease control strategies for pigs... - Genetic and antigenic characterization of H1 influenza viruses from United States swine from 2008Alessio Lorusso
Virus and Prion Disease Research Unit, USDA ARS NADC, Ames, IA, USA
J Gen Virol 92:919-30. 2011..Serological cross-reactivity paired with antigenic cartography demonstrated that the viruses in the different phylogenetic clusters are also antigenically divergent... - Influenza virus coinfection with Bordetella bronchiseptica enhances bacterial colonization and host responses exacerbating pulmonary lesionsCrystal L Loving
Respiratory Diseases of Livestock Research Unit, USDA, Agricultural Research Service, National Animal Disease Center, Ames, IA 50010, USA
Microb Pathog 49:237-45. 2010..Overall, Flu infection increased Bb colonization and enhanced production of proinflammatory mediators that likely contribute to exacerbated pulmonary lesions... - Detection of anti-influenza A nucleoprotein antibodies in pigs using a commercial influenza epitope-blocking enzyme-linked immunosorbent assay developed for avian speciesJanice R Ciacci-Zanella
Virus and Prion Diseases of Livestock Research Unit, National Animal Disease Center, USDA ARS, 1920 Dayton Road, Ames, IA 50010, USA
J Vet Diagn Invest 22:3-9. 2010..Overall, the assay showed excellent diagnostic performance against the range of influenza subtypes investigated and could serve as a useful screening assay for swine... - One-step real-time RT-PCR for pandemic influenza A virus (H1N1) 2009 matrix gene detection in swine samplesAlessio Lorusso
Virus and Prion Diseases Research Unit, National Animal Disease Center, USDA ARS, Ames, IA 50010, USA
J Virol Methods 164:83-7. 2010.... - Swine influenza matrix 2 (M2) protein contributes to protection against infection with different H1 swine influenza virus (SIV) isolatesPravina Kitikoon
College of Veterinary Medicine, Iowa State University, Ames, IA, USA
Vaccine 28:523-31. 2009..This study found that the M2 protein has potential as a vaccine for SIV-associated disease prevention. However, development of an immune response towards the major envelope HA protein was required to reduce SIV shedding... - Novel swine influenza virus subtype H3N1, United StatesPorntippa Lekcharoensuk
Virus and Prion Disease of Livestock Research Unit, National Animal Disease Center, US Department of Agriculture/ARS, 2300 Dayton Avenue, Ames, IA 50010, USA
Emerg Infect Dis 12:787-94. 2006..Further surveillance will help determine whether this novel subtype will continue to circulate in swine populations... - Identification and molecular cloning of a novel porcine parvovirusAndrew K Cheung
Virus and Prion Research Unit, National Animal Disease Center, PO Box 70, Ames, IA 50010, USA
Arch Virol 155:801-6. 2010..Whereas the ORF3-encoded proteins of bocaviruses share significant similarity with each other, the PPV4 ORF3 encoded protein does not exhibit homology with any protein in the GenBank non-redundant database...