Research Topics
| D E SwayneSummaryAffiliation: Agricultural Research Service Country: USA Publications
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Detail Information
Publications
Phylogenetic diversity among low-virulence newcastle disease viruses from waterfowl and shorebirds and comparison of genotype distributions to those of poultry-origin isolatesL Mia Kim
USDA ARS SouthEast Poultry Research Laboratory, Athens, GA 30605, USA
J Virol 81:12641-53. 2007....
Recommendations from the avian influenza vaccine workshopDavid E Swayne
U.S. Department of Agriculture, Agricultural Research Service, Southeast Poultry Research Laboratory, Athens, GA 30605, USA
Ann N Y Acad Sci 1081:226-7. 2006
Occupational and consumer risks from avian influenza virusesD E Swayne
Southeast Poultry Research Laboratory, Agricultural Research Service, US Department of Agriculture, Athens, GA 30605, USA
Dev Biol (Basel) 124:85-90. 2006..Cooking and pasteurisation are effective methods of killing AI viruses. Proper vaccination of poultry has been shown to prevent HPAI virus from localising in the meat...
Pathogenicity of avian influenza viruses in poultryD E Swayne
Southeast Poultry Research Laboratory, Agricultural Research Service, US Department of Agriculture, Athens, GA 30605, USA
Dev Biol (Basel) 124:61-7. 2006..Across all bird species, the ability to produce severe disease and death is associated with high virus replication titres in the host, especially in specific tissues such as brain and heart...
Principles for vaccine protection in chickens and domestic waterfowl against avian influenza: emphasis on Asian H5N1 high pathogenicity avian influenzaDavid E Swayne
U S Department of Agriculture, Agricultural Research Service, Southeast Poultry Research Laboratory, Athens, GA 30605, USA
Ann N Y Acad Sci 1081:174-81. 2006..The recombinant fowlpox-H5-AI vaccine has provided similar protection, but the vaccine is used only in chickens and with the advantage of application at 1 day of age in the hatchery...
Heat inactivation of avian influenza and Newcastle disease viruses in egg productsDavid E Swayne
Southeast Poultry Research Laboratory, Agricultural Research Service, United States Department of Agriculture, Athens, GA 30605, USA
Avian Pathol 33:512-8. 2004..By contrast, the HPAI virus was inactivated in liquid egg products but not in dried egg whites when using the low-temperature industry pasteurization protocol...
Application of new vaccine technologies for the control of transboundary diseasesD E Swayne
Southeast Poultry Research Laboratory, Agricultural Research Service, U S Department of Agriculture, Athens, GA 30605, USA
Dev Biol (Basel) 119:219-28. 2004..Mass application technologies of new virus or bacterial vector systems will provide economic incentives for adoption over current labour-intensive manual individual bird injection methods used with today's AI vaccines...
Vaccines for List A poultry diseases: emphasis on avian influenzaD E Swayne
Southeast Poultry Research Laboratory, U S Department of Agriculture, Agricultural Research Service, Athens, GA 30605, USA
Dev Biol (Basel) 114:201-12. 2003..Differentiation is necessary for outbreak surveillance and trade. The use of AI vaccines varies with individual countries and for different AI virus subtypes...
Recombinant paramyxovirus type 1-avian influenza-H7 virus as a vaccine for protection of chickens against influenza and Newcastle diseaseD E Swayne
USDA ARS, Southeast Poultry Research Laboratory, Athens, GA 30605 2195, USA
Avian Dis 47:1047-50. 2003..This demonstrates the potential for NDV for use as a vaccine vector in expressing AIV proteins...
Fatal encephalitis and myocarditis in young domestic geese (Anser anser domesticus) caused by West Nile virusD E Swayne
U S Department of Agriculture, Agricultural Research Service, Southeast Poultry Research Laboratory, 934 College Station Road, Athens, GA 30605, USA
Emerg Infect Dis 7:751-3. 2001..Based on this experimental study and a field outbreak in Israel, WN virus is a disease threat to young goslings and viremia levels are potentially sufficient to infect mosquitoes and transmit WN virus to other animal species...
Domestic poultry and SARS coronavirus, southern ChinaDavid E Swayne
Southeast Poultry Research Laboratory, Agricultural Research Service, U S Department of Agriculture, Athens, Georgia 30605, USA
Emerg Infect Dis 10:914-6. 2004..This finding suggests that domestic poultry were unlikely to have been the reservoir, or associated with dissemination, of SARS coronavirus in the animal markets of southern China...
Inactivated North American and European H5N2 avian influenza virus vaccines protect chickens from Asian H5N1 high pathogenicity avian influenza virusDavid E Swayne
United States Department of Agriculture, Southeast Poultry Research Laboratory, Agricultural Research Service, 934 College Station Road, Athens, GA 30605, USA
Avian Pathol 35:141-6. 2006..They will be an adjunct to biosecurity measures to reduce virus transmission...
Characterization of highly pathogenic H5N1 avian influenza A viruses isolated from South KoreaChang-Won Lee
Southeast Poultry Research Laboratory, USDA-ARS, 934 College Station Rd, Athens, GA 30605, USA
J Virol 79:3692-702. 2005....
Pathobiology of A/chicken/Hong Kong/220/97 (H5N1) avian influenza virus in seven gallinaceous speciesL E Perkins
Southeast Poultry Research Laboratory, USDA, ARS, Athens, GA 30605, USA
Vet Pathol 38:149-64. 2001..The pathobiologic features were analogous to those experimentally induced with other HPAI viruses in domestic poultry...
Comparisons of highly virulent H5N1 influenza A viruses isolated from humans and chickens from Hong KongD L Suarez
Southeast Poultry Research Laboratory, USDA, ARS, Athens, Georgia 30605, USA
J Virol 72:6678-88. 1998....
Protection against diverse highly pathogenic H5 avian influenza viruses in chickens immunized with a recombinant fowlpox vaccine containing an H5 avian influenza hemagglutinin gene insertD E Swayne
Southeast Poultry Research Laboratory, United States Department of Agriculture, Agriculture Research Service, Athens, GA 30503, USA
Vaccine 18:1088-95. 2000....
Development and evaluation of an avian influenza, neuraminidase subtype 1, indirect enzyme-linked immunosorbent assay for poultry using the differentiation of infected from vaccinated animals control strategyY Liu
Poultry Diagnostic and Research Center, Department of Population Health, College of Veterinary Medicine, University of Georgia, 953 College Station Road, Athens, GA 30602, USA
Avian Dis 54:613-21. 2010..Therefore, N1-ELISA can facilitate a vaccination strategy with differentiation of infected from vaccinated animals using a neuraminidase heterologous approach...
Is the occurrence of avian influenza virus in Charadriiformes species and location dependent?B A Hanson
Southeastern Cooperative Wildlife Disease Study, Department of Population Health, College of Veterinary Medicine, The University of Georgia, Athens, Georgia 30602, USA
J Wildl Dis 44:351-61. 2008..These results suggest that AIV infection among shorebirds (Scolopacidae) may be localized, species specific, and highly variable in relation to AIV subtype diversity...
Vaccines protect chickens against H5 highly pathogenic avian influenza in the face of genetic changes in field viruses over multiple yearsD E Swayne
Southeast Poultry Research Laboratory, USDA ARS, 934 College Station Road, Athens, GA 30605, USA
Vet Microbiol 74:165-72. 2000....
Evaluation of a high-pathogenicity H5N1 avian influenza A virus isolated from duck meatT M Tumpey
Southeast Poultry Research Laboratory, USDA, Agricultural Research Service, Athens, GA 30605, USA
Avian Dis 47:951-5. 2003..The presence of an H5N1 influenza virus in ducks bearing a HA gene that is highly similar to those of the pathogenic 1997 human/poultry H5N1 viruses raises the possibility of reintroduction of HPAI to chickens and humans...
Pathobiology of H5N2 Mexican avian influenza virus infections of chickensD E Swayne
US Department of Agriculture, Southeast Poultry Research Laboratory, Athens, GA, USA
Vet Pathol 34:557-67. 1997....
Efficacy of vaccines in chickens against highly pathogenic Hong Kong H5N1 avian influenzaD E Swayne
USDA, Agriculture Research Service, Southeast Poultry Research Laboratory, Athens, GA 30605, USA
Avian Dis 45:355-65. 2001..Existing vaccines will protect poultry from mortality and reduce virus replication from the new HP AIV strain that can infect both poultry and humans...
Existing antivirals are effective against influenza viruses with genes from the 1918 pandemic virusTerrence M Tumpey
Southeast Poultry Research Laboratory, United States Department of Agriculture, Athens, GA 30605, USA
Proc Natl Acad Sci U S A 99:13849-54. 2002..These data suggest that current antiviral strategies would be effective in curbing the dangers of a re-emergent 1918 or 1918-like virus...
Pathogenesis and pathobiology of avian influenza virus infection in birdsM J Pantin-Jackwood
Southeast Poultry Research Laboratory, Agricultural Research Service, United States Department of Agriculture, 934 College Station Road, Athens, Georgia 30605, USA
Rev Sci Tech 28:113-36. 2009....
Validation of egg yolk antibody testing as a method to determine influenza status in white leghorn hensJ R Beck
Southeast Poultry Research Laboratory, USDA-ARS, 934 College Station Road, Athens, GA 30605, USA
Avian Dis 47:1196-9. 2003..Antibody is detected earlier in the serum than in the yolk and antibody is detected earlier from birds exposed to a live infection compared to birds vaccinated with an inactivated oil emulsion vaccine...
Diagnostic approach for differentiating infected from vaccinated poultry on the basis of antibodies to NS1, the nonstructural protein of influenza A virusTerrence M Tumpey
Southwest Poultry Research Laboratory, Agricultural Research Service, US Department of Agriculture, College of Veterinary Medicine, University of Georgia, Athens, Georgia
J Clin Microbiol 43:676-83. 2005..These results demonstrate the potential benefit of a simple, specific ELISA for anti-NS1 antibodies that may have diagnostic value for the poultry industries...
Characterization and efficacy determination of commercially available Central American H5N2 avian influenza vaccines for poultryDawn Eggert
Southeast Poultry Research Laboratory, Agricultural Research Service, United States Department of Agriculture, 934 College Station Road, Athens, GA 30605, USA
Vaccine 28:4609-15. 2010....
Characterization of recent H5 subtype avian influenza viruses from US poultryChang-Won Lee
Southeast Poultry Research Laboratory, USDA-ARS, 934 College Station Road, Athens, GA 30605, USA
Avian Pathol 33:288-97. 2004..The outbreak in Texas with a more chicken-adapted H5N3 virus underscores the importance of ongoing surveillance and control efforts regarding the H5 subtype AI virus in the US...
Avian influenza vaccination in North America: strategies and difficultiesD L Suarez
Southeast Poultry Research Laboratory, Athens, GA 30605, USA
Dev Biol (Basel) 124:117-24. 2006..Therefore, periodical evaluation of the vaccine to the field strain is necessary to maintain good protection from clinical disease and virus shedding...
Pathogenicity of two Egyptian H5N1 highly pathogenic avian influenza viruses in domestic ducksJ L Wasilenko
United States Department of Agriculture, Athens, GA 30605, USA
Arch Virol 156:37-51. 2011....
Current developments in avian influenza vaccines, including safety of vaccinated birds as foodD E Swayne
Southeast Poultry Research Laboratory, Agricultural Research Service, Department of Agriculture, Athens, Georgia 30605, USA
Dev Biol (Basel) 130:123-33. 2007....
Variability in pathobiology of South Korean H5N1 high-pathogenicity avian influenza virus infection for 5 species of migratory waterfowlY K Kwon
Southeast Poultry Research Laboratory, Agricultural Research Service, US Department of Agriculture, Athens, Georgia, USA
Vet Pathol 47:495-506. 2010....
Comparative susceptibility of selected avian and mammalian species to a Hong Kong-origin H5N1 high-pathogenicity avian influenza virusL E L Perkins
Southeast Poultry Research Laboratory, USDA-ARS, 934 College Station Road, Athens, GA 30605, USA
Avian Dis 47:956-67. 2003....
Thermal inactivation of avian influenza and Newcastle disease viruses in chicken meatColleen Thomas
Exotic and Emerging Avian Viral Disease Research Unit, Southeast Poultry Research Laboratory, Agricultural Research Service, U S Department of Agriculture, 934 College Station Road, Athens, Georgia 30605, USA
J Food Prot 71:1214-22. 2008..9 degrees C for less than 1 s...
Experimental study to determine if low-pathogenicity and high-pathogenicity avian influenza viruses can be present in chicken breast and thigh meat following intranasal virus inoculationDavid E Swayne
USDA, Agricultural Research Service, Southeast Poultry Research Laboratory, 934 College Station Road, Athens, GA 30605, USA
Avian Dis 49:81-5. 2005....
Avian influenza and Newcastle diseaseDavid E Swayne
USDA-Agricultural Research Service, Southeast Poultry Research Laboratory, 934 College Station Rd, Athens, GA 30605, USA
J Am Vet Med Assoc 222:1534-40. 2003
Thermal inactivation of H5N1 high pathogenicity avian influenza virus in naturally infected chicken meatColleen Thomas
Southeast Poultry Research Laboratory, Exotic and Emerging Avian Viral Disease Research Unit, Agricultural Research Service, U S Department of Agriculture, 934 College Station Road, Athens, Gerogia 30605, USA
J Food Prot 70:674-80. 2007..S. Department of Agriculture Food Safety and Inspection Service time-temperature guidelines will inactivate Korea/03 in a heavily contaminated meat sample, such as those tested in this study, with a large margin of safety...
Comparative susceptibility of chickens and turkeys to avian influenza A H7N2 virus infection and protective efficacy of a commercial avian influenza H7N2 virus vaccineTerrence M Tumpey
Southeast Poultry Research Laboratory, United States Department of Agriculture, Agricultural Research Service, Athens, GA 30605, USA
Avian Dis 48:167-76. 2004..These results demonstrate the potential benefit of using an antigenically related 1997 H7N2 virus as a vaccine candidate for protection in poultry against a H7N2 virus isolate from 2002...
Pathogenicity and immunogenicity of influenza viruses with genes from the 1918 pandemic virusTerrence M Tumpey
Southeast Poultry Research Laboratory, Agricultural Research Service, U S Department of Agriculture, Athens, GA 30605, USA
Proc Natl Acad Sci U S A 101:3166-71. 2004..These data suggest a strategy of vaccination that would be effective against a reemergent 1918 or 1918-like virus...
Age at infection affects the pathogenicity of Asian highly pathogenic avian influenza H5N1 viruses in ducksM J Pantin-Jackwood
Southeast Poultry Research Laboratory, Agricultural Research Service, U S Department of Agriculture, 934 College Station Road, Athens, GA 30605, United States
Virus Res 130:151-61. 2007..High titers of virus in organs, high viral shedding, and variable mortality enable ducks to circulate H5N1 HPAI viruses...
Identification of the swine pathogen Serpulina hyodysenteriae in rheas (Rhea americana)N S Jensen
Enteric Diseases and Food Safety Research Unit, National Animal Disease Center, Ames, IA 50010, USA
Vet Microbiol 52:259-69. 1996..hyodysenteriae strains confirmed that rhea spirochetes R1 and NIV-1 were strains of S. hyodysenteriae. These results indicate that S. hyodysenteriae has a broader host range than previously recognized...
Single and combination diagnostic test efficiency and cost analysis for detection and isolation of avian influenza virus from wild bird cloacal swabsJennifer Lira
Southeast Poultry Research Laboratory, Agricultural Research Service, USDA, 934 College Station Road, Athens, GA 30605, USA
Avian Dis 54:606-12. 2010..In contrast, isolation in ECE via CAS and YS inoculation routes without prescreening by RRT-PCR was most efficient and cost-effective if the samples had an expected high frequency of AIV...
An evaluation of avian influenza diagnostic methods with domestic duck specimensErica Spackman
Southeast Poultry Research Laboratory, USDA, Agricultural Research Service, 934 College Station Road, Athens, GA 30605, USA
Avian Dis 53:276-80. 2009..At all time points AGID detected antibody in substantially fewer samples than either ELISA or HI assay...
Strategies and challenges for eliciting immunity against avian influenza virus in birdsDavid E Swayne
US Department of Agriculture, Agricultural Research Service, Exotic and Emerging Avian Viral Diseases Research Unit, Athens, GA, USA
Immunol Rev 225:314-31. 2008..In addition, newer technologies for AI vaccines will improve vaccine coverage by using mass application technologies for example by drinking water, by spray, or via injection in ovo or at the hatchery...
Improvements to the hemagglutination inhibition test for serological assessment of recombinant fowlpox-H5-avian-influenza vaccination in chickens and its use along with an agar gel immunodiffusion test for differentiating infected from noninfected vaccinaDavid E Swayne
Southeast Poultry Research Laboratory, Agricultural Research Service, U S Department of Agriculture, 934 College Station Road, Athens, Georgia 30605, USA
Avian Dis 51:697-704. 2007..In conclusion, we demonstrated that the rFP-H5 vaccine allowed easy serological differentiation of infected from noninfected birds in vaccinated populations of chickens when using standard AGID and HI tests...
Characterization of low pathogenicity avian influenza viruses isolated from wild birds in Mongolia 2005 through 2007Erica Spackman
U S Department of Agriculture, Agricultural Research Service, Southeast Poultry Research Laboratory, Athens, GA 30605, USA
Virol J 6:190. 2009..An important feature of Mongolia is that there is little domestic poultry production in the country, therefore AIV detection in wild birds would not likely be from spill-over from domestic poultry...
Development of Eurasian H7N7/PR8 high growth reassortant virus for clinical evaluation as an inactivated pandemic influenza vaccineSamadhan J Jadhao
Influenza Division, Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Atlanta, GA 30333, USA
Vaccine 26:1742-50. 2008..The vaccine candidate virus satisfied the agricultural safety requirements for chickens, proved safe in mice, and has entered in phase-I human clinical trial in the United States...
Influenza vaccines for avian speciesDarrell R Kapczynski
Exotic and Emerging Avian Viral Diseases Research Unit, Southeast Poultry Research Laboratory, USDA Agricultural Research Service South Atlantic Area, 934 College Station Road, Athens, GA 30605, USA
Curr Top Microbiol Immunol 333:133-52. 2009..In the current H5N1 HPAI epizootic, vaccines have been used in a variety of avian species as a part of an overall control program to aid in disease management and control...
Evaluation and attempted optimization of avian embryos and cell culture methods for efficient isolation and propagation of low pathogenicity avian influenza virusesKira A Moresco
Southeast Poultry Research Laboratory, Agricultural Research Service, US Department of Agriculture, Athens, GA 30605, USA
Avian Dis 54:622-6. 2010....
Avian influenza vaccines and therapies for poultryDavid E Swayne
Southeast Poultry Research Laboratory, Agricultural Research Service, US Department of Agriculture, 934 College Station Road, Athens, GA 30605, USA
Comp Immunol Microbiol Infect Dis 32:351-63. 2009..Other licensed AI vaccines include recombinant fowl poxvirus vector with an AI H5 insert and a recombinant Newcastle disease virus vector with an AI H5 gene insert. The latter vaccine can be mass administered via aerosol application...
Using mean infectious dose of high- and low-pathogenicity avian influenza viruses originating from wild duck and poultry as one measure of infectivity and adaptation to poultryDavid E Swayne
Southeast Poultry Research Laboratory, Agricultural Research Service, U S Department of Agriculture, 934 College Station Road, Athens, GA 30605, USA
Avian Dis 52:455-60. 2008....
Characterization of low-pathogenicity H5N1 avian influenza viruses from North AmericaErica Spackman
Southeast Poultry Research Laboratory, U S Department of Agriculture Agricultural Research Service, 934 College Station Road, Athens, GA 30605, USA
J Virol 81:11612-9. 2007....
H7N3 avian influenza virus found in a South American wild duck is related to the Chilean 2002 poultry outbreak, contains genes from equine and North American wild bird lineages, and is adapted to domestic turkeysErica Spackman
Southeast Poultry Research Laboratory, US Department of Agriculture ARS, 934 College Station Road, Athens, GA 30605, USA
J Virol 80:7760-4. 2006..The HA protein cleavage site and the results of pathogenesis studies in chickens were consistent with a low-pathogenicity virus, and the infective dose was 10(5) times higher for chickens than turkeys...
Phylogenetic analyses of type A influenza genes in natural reservoir species in North America reveals genetic variationErica Spackman
Southeast Poultry Research Laboratory, USDA ARS, 934 College Station Road, Athens, GA 30605, USA
Virus Res 114:89-100. 2005..A lack of clear temporal or spatial grouping shows that multiple lineages of virus co-circulate and precludes the development of an epidemiological map for influenza virus from these species...
H5N2 avian influenza outbreak in Texas in 2004: the first highly pathogenic strain in the United States in 20 years?Chang Won Lee
Southeast Poultry Research Laboratory, USDA ARS, Athens, GA 30605, USA
J Virol 79:11412-21. 2005..Our study provides the genetic and biologic characteristics of the TX/04 isolate, which highlight the complexity of the polygenic nature of the virulence of influenza viruses...
Microassay for measuring thermal inactivation of H5N1 high pathogenicity avian influenza virus in naturally infected chicken meatDavid E Swayne
Southeast Poultry Research Laboratory, Exotic and Emerging Avian Viral Disease Research Unit, Agricultural Research Service, U S Department of Agriculture, Athens, Georgia 30605, USA
Int J Food Microbiol 108:268-71. 2006..A change in coloration from pink-tan to white was associated with a loss in recovery of infectious virus. The microassay provided a predictable and reproducible method to measure thermal inactivation of HPAI virus in chicken meat...
Characterization of a highly pathogenic H5N1 avian influenza A virus isolated from duck meatTerrence M Tumpey
Southeast Poultry Research Laboratory, U S Department of Agriculture, Agricultural Research Service, Athens, Georgia 30605, USA
J Virol 76:6344-55. 2002..The isolation of a highly pathogenic H5N1 influenza virus from poultry indicates that such viruses are still circulating in China and may present a risk for transmission of the virus to humans...
Evidence of avian metapneumovirus subtype C infection of wild birds in Georgia, South Carolina, Arkansas and Ohio, USAE A Turpin
United States Department of Agriculture, Southeast Poultry Research Laboratory, Agricultural Research Service, Athens, GA 30605, USA
Avian Pathol 37:343-51. 2008....
Avian influenza viruses in Minnesota ducks during 1998-2000B A Hanson
Southeastern Cooperative Wildlife Disease Study, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
Avian Dis 47:867-71. 2003..Viruses in the H5, H7, and H9 subtypes, which are associated with high-pathogenicity influenza in poultry or recent infections in humans, were not uncommon, and each of these subtypes was isolated in 2 out of the 3 years of surveillance...
Immediate early responses of avian tracheal epithelial cells to infection with highly pathogenic avian influenza virusL Sarmento
Southeast Poultry Research Laboratory, ARS USDA, Athens, GA 30605, USA
Dev Biol (Basel) 132:175-83. 2008....
Susceptibility of laughing gulls (Larus atricilla) to H5N1 and H5N3 highly pathogenic avian influenza virusesLaura E Leigh Perkins
USDA, Agricultural Research Service, Southeast Poultry Research Laboratory, 934 College Station Road, Athens, GA 30605, USA
Avian Dis 46:877-85. 2002..Antibodies to influenza viruses as determined with the agar gel precipitin test at 14 DPI were detected only in the two tern/SA-inoculated gulls and not in the two chicken/HK-inoculated gulls...
Immunogenicity of fowlpox virus expressing the avian influenza virus H5 gene (TROVAC AIV-H5) in catsKemal Karaca
Merial Ltd, 115 Transtech Drive, Athens, Georgia 30601, USA
Clin Diagn Lab Immunol 12:1340-2. 2005..The vaccine described in this study and other poxvirus-vectored vaccines may be of value for the prophylaxis of AI virus-associated morbidity and mortality in mammals...
Amelioration of influenza virus pathogenesis in chickens attributed to the enhanced interferon-inducing capacity of a virus with a truncated NS1 geneAngela N Cauthen
Southeast Poultry Research Laboratory, ARS USDA, 934 College Station Road, Athens, GA 30605, USA
J Virol 81:1838-47. 2007..This suggests that the IFN-inducing and IFN induction suppression phenotypes of AIV should be considered when characterizing strains of influenza virus...
Development and evaluation of a real-time Taqman RT-PCR assay for the detection of infectious bronchitis virus from infected chickensScott A Callison
Department of Population Health, Poultry Diagnostic and Research Center, 953 College Station Road, University of Georgia, Athens, GA 30602, USA
J Virol Methods 138:60-5. 2006..The test was extremely sensitive and specific, and can be used to quantitate viral genomic RNA in clinical samples...
An avian influenza virus from waterfowl in South America contains genes from North American avian and equine lineagesErica Spackman
Southeast Poultry Research Laboratory, U S Department of Agriculture Agricultural Research Service, 934 College Station Road, Athens, GA 30605, USA
Avian Dis 51:273-4. 2007..Two genes were most closely related to North American wild aquatic bird virus lineages and one gene was most closely related to an equine influenza virus from South America...
Agroterrorism, biological crimes, and biowarfare targeting animal agriculture. The clinical, pathologic, diagnostic, and epidemiologic features of some important animal diseasesT M Wilson
Emergency Programs, Veterinary Services, Animal and Plant Health Inspection Service, United States Department of Agriculture, Armed Forces Medical Intelligence Center, Fort Detrick, Maryland, USA
Clin Lab Med 21:549-91. 2001..The framework for this vigilance must be an intelligence system sensitive to the needs of agriculture and a first-class animal disease diagnostic surveillance and response system...
Domestic pigs have low susceptibility to H5N1 highly pathogenic avian influenza virusesAleksandr S Lipatov
Southeast Poultry Research Laboratory, Agricultural Research Service, United States Department of Agriculture, Athens, Georgia, United States of America
PLoS Pathog 4:e1000102. 2008....
Experimental infection of turkeys with avian pneumovirus and either Newcastle disease virus or Escherichia coliElizabeth A Turpin
Southeast Poultry Research Laboratory, United States Department of Agriculture, Agricultural Research Service, Athens, GA 30605, USA
Avian Dis 46:412-22. 2002..These lesions were not present in the single APV, NDV, or E coli groups. These results demonstrate that coinfection with APV and NDV can result in clinical signs and lesions similar to those in field outbreaks of APV...
Development and evaluation of a blocking enzyme-linked immunosorbent assay for detection of avian metapneumovirus type C-specific antibodies in multiple domestic avian speciesElizabeth A Turpin
Southeast Poultry Research Laboratory, Agricultural Research Service, US Department of Agriculture, Athens, Georgia 30605, USA
J Clin Microbiol 41:3579-83. 2003..This is the first diagnostic assay for the detection of aMPV-C-specific antibodies from multiple avian species in the United States...
Limited susceptibility and lack of systemic infection by an H3N2 swine influenza virus in intranasally inoculated chickensColleen Thomas
Southeast Poultry Research Laboratory, Agricultural Research Service, U S Department of Agriculture, 934 College Station Road, Athens, GA 30605, USA
Avian Dis 52:498-501. 2008..The comprehensive pathogenesis study demonstrated that the virus did not cause systemic infections in WPR chickens, and feeding breast and thigh meat from the NC/04 SIV-inoculated WPR to WL chickens did not transmit NC/04 SIV...
Pathogenicity of a Hong Kong-origin H5N1 highly pathogenic avian influenza virus for emus, geese, ducks, and pigeonsLaura E Leigh Perkins
Southeast Poultry Research Laboratory, United States Department of Agriculture, Agricultural Research Service, Athens, GA 30605, USA
Avian Dis 46:53-63. 2002..n. inoculation with the HK/220 virus, whereas ducks and pigeons are more resistant. These latter two species probably played a minimal epidemiologic role in the perpetuation of the H5N1 Hong Kong-origin influenza viruses...
Susceptibility of wood ducks to H5N1 highly pathogenic avian influenza virusJustin D Brown
Southeastern Cooperative Wildlife Disease Study, Department of Population Health, Wildlife Health Building, College of Veterinary Medicine, The University of Georgia, Athens, Georgia 30602, USA
J Wildl Dis 43:660-7. 2007....
Pathogenesis of H5N1 influenza virus infections in mice and ferret models differs according to respiratory tract or digestive system exposureAleksandr S Lipatov
Southeast Poultry Research Laboratory, Agricultural Research Service, United States Department of Agriculture, Athens, Georgia, USA
J Infect Dis 199:717-25. 2009..Some data suggest digestive system involvement. However, direct evidence of alimentary transmission and infection in mammals is lacking...
Canada geese and the epidemiology of avian influenza virusesMark T Harris
Southeastern Cooperative Wildlife Disease Study, Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
J Wildl Dis 46:981-7. 2010....
Bronchointerstitial pneumonia in guinea pigs following inoculation with H5N1 high pathogenicity avian influenza virusY K Kwon
Southeast Poultry Research Laboratory, Agricultural Research Service, United States Department of Agriculture, Athens, Georgia 30605, USA
Vet Pathol 46:138-41. 2009..The localized respiratory disease in guinea pigs with H5N1 viruses was very similar to that of H3N2 and H1N1 influenza in humans and was less severe than reported for H5N1 human cases...
Varied pathogenicity of a Hong Kong-origin H5N1 avian influenza virus in four passerine species and budgerigarsL E L Perkins
United States Department of Agriculture, Agricultural Research Service, Southeast Poultry Research Laboratory, 934 College Station Road, Athens, GA 30605, USA
Vet Pathol 40:14-24. 2003..In addition, neurotropism is a recurrent feature among birds that eventually succumb to infection...
Thermal inactivation of H5N2 high-pathogenicity avian influenza virus in dried egg white with 7.5% moistureColleen Thomas
US Department of Agriculture, Agricultural Research Service, Exotic and Emerging Avian Viral Disease Research Unit, Southeast Poultry Research Laboratory, 934 College Station Road, Athens, Georgia 30605, USA
J Food Prot 72:1997-2000. 2009..For example, these calculations predict that a 7-log reduction would take only 2.6 days at 54.4 degrees C...
Understanding the complex pathobiology of high pathogenicity avian influenza viruses in birdsDavid E Swayne
Southeast Poultry Research Laboratory, Agricultural Research Service, U S Department of Agriculture, 934 College Station Road, Athens, GA 30605, USA
Avian Dis 51:242-9. 2007..Across all bird species, the ability to produce severe disease and death is associated with high virus replication titers in the host, especially in specific tissues such as brain and heart...
Experimental infections of herring gulls (Larus argentatus) with H5N1 highly pathogenic avian influenza viruses by intranasal inoculation of virus and ingestion of virus-infected chicken meatJustin D Brown
Southeastern Cooperative Wildlife Disease Study, Department of Population Health, Wildlife Health Building, College of Veterinary Medicine, The University of Georgia, Athens, GA 30602, USA
Avian Pathol 37:393-7. 2008....
Susceptibility of North American ducks and gulls to H5N1 highly pathogenic avian influenza virusesJustin D Brown
College of Veterinary Medicine, University of Georgia, Athens, Georgia 30602, USA
Emerg Infect Dis 12:1663-70. 2006....
Pathobiology of Asian highly pathogenic avian influenza H5N1 virus infections in ducksMary J Pantin Jackwood
Southeast Poultry Research Laboratory, U S Department of Agriculture, Agriculture Research Service, 934 College Station Road, Athens, GA 30605, USA
Avian Dis 51:250-9. 2007....
Detection of H5N1 high-pathogenicity avian influenza virus in meat and tracheal samples from experimentally infected chickensAmaresh Das
Southeast Poultry Research Laboratory, Agricultural Research Service, U S Department of Agriculture, 934 College Station Road, Athens, Georgia 30605, USA
Avian Dis 52:40-8. 2008..In addition, the modified RNA extraction and RRT-PCR test on meat samples provide a rapid and sensitive method of identifying HPAI virus in illegal contraband or domestic meat samples...
Avian paramyxoviruses in shorebirds and gullsLaura L Coffee
Southeastern Cooperative Wildlife Disease Study, Department of Population Health, College of Veterinary Medicine, The University of Georgia, Athens, Georgia 30602, USA
J Wildl Dis 46:481-7. 2010..The higher prevalence of APMV in Ruddy Turnstones mirrors results observed for avian influenza viruses in shorebirds and may suggest similar modes of transmission...
Avian influenza viruses and paramyxoviruses in wintering and resident ducks in TexasBritta A Hanson
Southeastern Cooperative Wildlife Disease Study, Department of Population Health, College of Veterinary Medicine, The University of Georgia, Athens, GA 30602, USA
J Wildl Dis 41:624-8. 2005..7% of teal in February 2002. The season of isolation of both viruses and the majority of the AIV subtypes detected in this study are not typical based on previous reports of these viruses from North American ducks...
Major histocompatibility complex and background genes in chickens influence susceptibility to high pathogenicity avian influenza virusHenry D Hunt
Avian Disease and Oncology Laboratory, Agricultural Research Service, U S Department of Agriculture, 3606 East Mount Hope Road East, East Lansing, MI 48823, USA
Avian Dis 54:572-5. 2010..9 days, suggesting differences in pathogenesis. The data show that the MHC has some influence on resistance to AI, but less than previously proposed, and non-MHC background genes may have a bigger influence on resistance than the MHC...
Experimental infection of swans and geese with highly pathogenic avian influenza virus (H5N1) of Asian lineageJustin D Brown
Southeastern Cooperative Wildlife Disease Study, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
Emerg Infect Dis 14:136-42. 2008..These results suggest that the potential for HPAI (H5N1) viral shedding and the movement of infected birds may be species-dependent and can help explain observed deaths associated with HPAI (H5N1) infection in anseriforms in Eurasia...
Infectious and lethal doses of H5N1 highly pathogenic avian influenza virus for house sparrows (Passer domesticus) and rock pigeons (Columbia livia)Justin D Brown
Southeastern Cooperative Wildlife Disease Study, Department of Population Health, Wildlife Health Building, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
J Vet Diagn Invest 21:437-45. 2009..When infection did occur, the duration of viral shedding was brief, and viral titers were low. The data suggests that pigeons would contribute little to the transmission and spread of H5N1 HPAI virus in poultry...
Susceptibility of turkeys to pandemic-H1N1 virus by reproductive tract inseminationMary Pantin-Jackwood
Exotic and Emerging Avian Viral Diseases Research Unit, Agricultural Research Service, US Department of Agriculture, Athens, Georgia 30605 USA
Virol J 7:27. 2010..This understanding of virus exposure provides an improved understanding of the pathogenesis of the disease and can improve poultry husbandry to prevent disease outbreaks...
Protection of mice and poultry from lethal H5N1 avian influenza virus through adenovirus-based immunizationWentao Gao
Department of Surgery and Medicine, University of Pittsburgh School of Medicine, Molecular Medicine Institute, Suite 412, 300 Technology Drive, Pittsburgh, PA 15219, USA
J Virol 80:1959-64. 2006....
A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmissionTerrence M Tumpey
Influenza Branch, Mailstop G 16, Division of Viral and Ricksettial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA 30333, USA
Science 315:655-9. 2007..These findings confirm an essential role of hemagglutinin receptor specificity for the transmission of influenza viruses among mammals...
A combination in-ovo vaccine for avian influenza virus and Newcastle disease virusJohn Steel
Department of Microbiology, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
Vaccine 26:522-31. 2008..We propose that this virus has potential as a safe in-ovo live, attenuated, bivalent avian influenza and Newcastle disease virus vaccine...
Comparative pathobiology of low and high pathogenicity H7N3 Chilean avian influenza viruses in chickensYava L Jones
School of Veterinary Medicine, Tuskegee University, Tuskegee, AL 36083, USA
Avian Dis 48:119-28. 2004..Interestingly, the H7N3/LP AI virus on intravenous inoculation replicated in cardiac myocytes, a feature of HPAI and not LPAI viruses, which further supports the theory that the H7N3/LP AI virus was in transition from LP to HP...
Development and use of fowlpox vectored vaccines for avian influenzaMichel Bublot
Merial SAS, Discovery Research, 254, rue Marcel Merieux, 69007 Lyon, France
Ann N Y Acad Sci 1081:193-201. 2006..TROVAC-H5 has recently been shown to be immunogenic in cats and could therefore also be considered for use in mammals...
Development and evaluation of an Influenza virus subtype H7N2 vaccine candidate for pandemic preparednessClaudia Pappas
Influenza Division, Mailstop G 16, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
Clin Vaccine Immunol 14:1425-32. 2007..These studies indicate that H7N2-PR8 is immunogenic, safe, and protective in animal models; these are the essential attributes to qualify for phase I human clinical trials as a prepandemic vaccine...
Movements of birds and avian influenza from Asia into AlaskaKevin Winker
University of Alaska Museum, Fairbanks, Alaska 99775, USA
Emerg Infect Dis 13:547-52. 2007....
Efficacy of a fowlpox-vectored avian influenza H5 vaccine against Asian H5N1 highly pathogenic avian influenza virus challengeMichel Bublot
Merial SAS, Discovery Research, Lyon 69007, France
Avian Dis 51:498-500. 2007..Together, these results confirm the excellent level of protection induced by rFP-AIV-H5 in SPF chickens against two recent Asian HPAI H5N1 isolates...
Characterization of the reconstructed 1918 Spanish influenza pandemic virusTerrence M Tumpey
Influenza Branch, Mailstop G 16, Division of Viral and Rickettsial Diseases DVRD, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Atlanta, GA 30333, USA
Science 310:77-80. 2005..Moreover, the coordinated expression of the 1918 virus genes most certainly confers the unique high-virulence phenotype observed with this pandemic virus...
Efficacy of two H5N9-inactivated vaccines against challenge with a recent H5N1 highly pathogenic avian influenza isolate from a chicken in ThailandMichel Bublot
Merial SAS, R and D, Lyon 69007, France
Avian Dis 51:332-7. 2007..Altogether, these data indicate that both vaccines protected very well against morbidity and mortality and reduced or prevented shedding induced by direct or contact exposure to Asian H5N1 HPAI virus...
The evolutionary genetics and emergence of avian influenza viruses in wild birdsVivien G Dugan
Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
PLoS Pathog 4:e1000076. 2008....
Influenza A virus infections in land birds, People's Republic of ChinaA Townsend Peterson
Natural History Museum and Biodiversity Research Center, University of Kansas, Lawrence, Kansas 66045, USA
Emerg Infect Dis 14:1644-6. 2008..Influenza A infection was found, particularly among migratory species. Surveillance programs for monitoring spread of these viruses need to be redesigned...
Global host immune response: pathogenesis and transcriptional profiling of type A influenza viruses expressing the hemagglutinin and neuraminidase genes from the 1918 pandemic virusJohn C Kash
Department of Microbiology, School of Medicine, University of Washington, Seattle, Washington 98195 8070, USA
J Virol 78:9499-511. 2004..These studies document clear differences in gene expression profiles that were correlated with pulmonary disease pathology induced by virulent and attenuated influenza virus infections...
