Affiliation: Agricultural Research Service
Costa Hurtado M, Afonso C, Miller P, Shepherd E, Cha R, Smith D, et al
. Previous infection with virulent strains of Newcastle disease virus reduces highly pathogenic avian influenza virus replication, disease, and mortality in chickens. Vet Res. 2015;46:97 pubmed publisher
..The information obtained from these studies helps to understand the possible interactions and outcomes of infection (disease and virus shedding) when HPAIV and NDV co-infect chickens in the field. ..
Spackman E, Pantin Jackwood M, Swayne D, Suarez D, Kapczynski D. Impact of route of exposure and challenge dose on the pathogenesis of H7N9 low pathogenicity avian influenza virus in chickens. Virology. 2015;477:72-81 pubmed publisher
..Virus was shed at higher titers and spread to the kidneys in chickens inoculated by the intravenous route. Challenge experiments with three other human-origin H7N9 viruses showed a similar pattern of virus replication. ..
Spackman E, Pantin Jackwood M. Practical aspects of vaccination of poultry against avian influenza virus. Vet J. 2014;202:408-15 pubmed publisher
Spackman E, Pantin Jackwood M, Kapczynski D, Swayne D, Suarez D. H5N2 Highly Pathogenic Avian Influenza Viruses from the US 2014-2015 outbreak have an unusually long pre-clinical period in turkeys. BMC Vet Res. 2016;12:260 pubmed
..The unusually long mean death times, high levels of virus in feces, and increased adaptation of the later viruses may have contributed to the rapid spread of the virus during the peak of the outbreak. ..
Spackman E, Day J, Pantin Jackwood M. Astrovirus, reovirus, and rotavirus concomitant infection causes decreased weight gain in broad-breasted white poults. Avian Dis. 2010;54:16-21 pubmed
..Cloacal shedding of TAstV-2 and TRotV was evaluated by reverse-transcription PCR testing of cloacal swabs and minimal differences were observed among the treatment groups...
Spackman E, Pedersen J, McKinley E, Gelb J. Optimal specimen collection and transport methods for the detection of avian influenza virus and Newcastle disease virus. BMC Vet Res. 2013;9:35 pubmed publisher
..5 ml), 4) transporting the swab wet in the vial or removing the swab prior to transport, or transporting the swab dry with no media, and 5) single swabs versus pooling 5 or 11 swabs per vial...
DeJesus E, Costa Hurtado M, Smith D, Lee D, Spackman E, Kapczynski D, et al
. Changes in adaptation of H5N2 highly pathogenic avian influenza H5 clade 126.96.36.199 viruses in chickens and mallards. Virology. 2016;499:52-64 pubmed publisher
..Increased virus adaptation to chickens was observed with the poultry H5N2 viruses; however these viruses retained high adaptation to mallards but pathogenicity was differently affected. ..
Spackman E, Gelb J, Preskenis L, Ladman B, Pope C, Pantin Jackwood M, et al
. The pathogenesis of low pathogenicity H7 avian influenza viruses in chickens, ducks and turkeys. Virol J. 2010;7:331 pubmed publisher
..However the severity of disease and degree of virus shed was not clearly correlated with any isolate or group of isolates, but relied on specific species and isolate combinations. ..
Spackman E, Swayne D. Vaccination of gallinaceous poultry for H5N1 highly pathogenic avian influenza: current questions and new technology. Virus Res. 2013;178:121-32 pubmed publisher
..Numerous technical improvements to these platforms and novel vaccine platforms for H5N1 vaccines have been reported, but most are not ready to be implemented in the field. ..