Affiliation: Agricultural Research Service
- Cryptosporidium parvum initiates inflammatory bowel disease in germfree T cell receptor-alpha-deficient miceR E Sacco
Veterinary Medical Research Institute, Iowa State University, Ames, USA
Am J Pathol 153:1717-22. 1998..Our results indicate that a single microbial species, C. parvum, is capable of triggering the development of IBD-like lesions in germfree TCR-alpha-deficient mice...
- Reduction in inflammation following blockade of CD18 or CD29 adhesive pathways during the acute phase of a spirochetal-induced colitis in miceR E Sacco
Veterinary Medical Research Institute, Iowa State University, Ames, IA, USA
Microb Pathog 29:289-99. 2000..The data provide evidence for a threshold number of PMNs necessary for lesion development and indicate that CD18, but not CD29, adhesive pathways are crucial for PMN recruitment in bacterial colitis...
- Restriction endonuclease analysis discriminates Bordetella bronchiseptica isolatesR E Sacco
USDA Agricultural Research Service, National Animal Disease Center, Ames, Iowa 50010, USA
J Clin Microbiol 38:4387-93. 2000..Based on the results presented herein, the combination of REA and ribotyping should provide valuable information in understanding the molecular epidemiology of B. bronchiseptica infections...
- Identification of new major histocompatibility complex class II restriction fragment length polymorphisms in a closed experimental line of Beltsville Small White turkeysR E Sacco
Respiratory Diseases of Livestock Research Unit, National Animal Disease Center, USDA Agricultural Research Service, Ames 50010, USA
Poult Sci 80:1109-11. 2001..Furthermore, no mixed lymphocyte reaction was observed between individuals within the BSW turkey line. The present results indicate that BSW turkeys represent a unique source of genetic diversity for MHC Class II haplotypes...
- Established T(H1) granulomatous responses induced by active Mycobacterium avium infection switch to T(H2) following challenge with Schistosoma mansoniRandy Sacco
Department of Pathology, University of Iowa College of Medicine, Iowa City 52242, USA
Clin Immunol 104:274-81. 2002..avium is modulated subsequent to co-infection with S. mansoni. The dominance of the T(H2) response observed in this model could have clinical implications in areas where parasites and mycobacteria co-exist...
- Comparative nitric oxide production by LPS-stimulated monocyte-derived macrophages from Ovis canadensis and Ovis ariesR E Sacco
National Animal Disease Center, USDA ARS, Ames, IA 50010, USA
Comp Immunol Microbiol Infect Dis 29:1-11. 2006....