R Pawlosky

Summary

Affiliation: Agricultural Research Service
Country: USA

Publications

  1. ncbi request reprint A chronic ethanol-feeding study in rhesus monkeys
    R J Pawlosky
    U S Department of Agriculture, Human Nutrition Research Center, Beltsville, Maryland, USA
    Lipids 34:S131-2. 1999
  2. ncbi request reprint A quantitative stable-isotope LC-MS method for the determination of folic acid in fortified foods
    R J Pawlosky
    Food Composition Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service USDA, 10300 Baltimore Ave, Beltsville, MD 20705, USA
    J Agric Food Chem 49:1282-6. 2001
  3. ncbi request reprint Physiological compartmental analysis of alpha-linolenic acid metabolism in adult humans
    R J Pawlosky
    Food Composition Laboratory, Beltsville, MD 20705, USA
    J Lipid Res 42:1257-65. 2001
  4. ncbi request reprint Determination of 5-methyltetrahydrofolic acid in human serum by stable-isotope dilution high-performance liquid chromatography-mass spectrometry
    R J Pawlosky
    Food Composition Laboratory Beltsville Human Nutrition Research Center, USDA, Beltsville, Maryland 20705, USA
    Anal Biochem 298:299-305. 2001
  5. ncbi request reprint Ethanol consumption alters electroretinograms and depletes neural tissues of docosahexaenoic acid in rhesus monkeys: nutritional consequences of a low n-3 fatty acid diet
    R J Pawlosky
    Food Composition Laboratory, Beltsville Human Nutrition Research Center ARS, USDA, Beltsville, Maryland 20705, USA
    Alcohol Clin Exp Res 25:1758-65. 2001
  6. ncbi request reprint Methods for determining the metabolism of alpha-linolenic acid in human subjects from intrinsically-labeled food
    Robert J Pawlosky
    Food Composition Laboratory, Beltsville, MD 20705, USA
    Forum Nutr 56:75-7. 2003
  7. ncbi request reprint Effects of beef- and fish-based diets on the kinetics of n-3 fatty acid metabolism in human subjects
    Robert J Pawlosky
    Food Composition Laboratory, Beltsville Human Nutrition Research Center, US Department of Agriculture, Beltsville, MD, USA
    Am J Clin Nutr 77:565-72. 2003
  8. ncbi request reprint Simultaneous quantitative determination of deuterium- and carbon-13-labeled essential fatty acids in rat plasma
    Yu Hong Lin
    Section of Nutritional Neuroscience, Laboratory of Membrane Biochemistry and Biophysics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892 9410, USA
    J Lipid Res 46:1974-82. 2005
  9. ncbi request reprint Compartmental analyses of plasma 13C- and 2H-labeled n-6 fatty acids arising from oral administrations of 13C-U-18:2n-6 and 2H5-20:3n-6 in newborn infants
    Robert J Pawlosky
    Laboratory of Metabolic Control, National Institutes on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, USA
    Pediatr Res 60:327-33. 2006
  10. ncbi request reprint Compartmental analyses of plasma n-3 essential fatty acids among male and female smokers and nonsmokers
    Robert J Pawlosky
    Laboratory of Metabolic Control, National Institutes on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA
    J Lipid Res 48:935-43. 2007

Detail Information

Publications10

  1. ncbi request reprint A chronic ethanol-feeding study in rhesus monkeys
    R J Pawlosky
    U S Department of Agriculture, Human Nutrition Research Center, Beltsville, Maryland, USA
    Lipids 34:S131-2. 1999
    ..There was a greater concentration of 4-hydroxynonenal in the plasma of alcohol-exposed monkeys compared to controls...
  2. ncbi request reprint A quantitative stable-isotope LC-MS method for the determination of folic acid in fortified foods
    R J Pawlosky
    Food Composition Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service USDA, 10300 Baltimore Ave, Beltsville, MD 20705, USA
    J Agric Food Chem 49:1282-6. 2001
    ..The specificity of the technique and quantitative accuracy of the method in various food substrates suggests that the method may be adapted for routine analysis in other fortified foods...
  3. ncbi request reprint Physiological compartmental analysis of alpha-linolenic acid metabolism in adult humans
    R J Pawlosky
    Food Composition Laboratory, Beltsville, MD 20705, USA
    J Lipid Res 42:1257-65. 2001
    ..In contrast, the much greater rate of transfer of mass from the plasma 20:5n-3 compartment to 22:5n-3 suggests that dietary eicosapentaenoic acid may be well utilized in the biosynthesis of 22:6n-3 in humans...
  4. ncbi request reprint Determination of 5-methyltetrahydrofolic acid in human serum by stable-isotope dilution high-performance liquid chromatography-mass spectrometry
    R J Pawlosky
    Food Composition Laboratory Beltsville Human Nutrition Research Center, USDA, Beltsville, Maryland 20705, USA
    Anal Biochem 298:299-305. 2001
    ..A highly accurate and specific method for the analysis of 5-MTHFA in serum has been developed utilizing stable isotope dilution mass spectrometry...
  5. ncbi request reprint Ethanol consumption alters electroretinograms and depletes neural tissues of docosahexaenoic acid in rhesus monkeys: nutritional consequences of a low n-3 fatty acid diet
    R J Pawlosky
    Food Composition Laboratory, Beltsville Human Nutrition Research Center ARS, USDA, Beltsville, Maryland 20705, USA
    Alcohol Clin Exp Res 25:1758-65. 2001
    ..Further diagnostic details of this condition have shown abnormalities in the electroretinogram (ERG) that include an increase in implicit times in the a- and b-waves and a depression of b-wave amplitude...
  6. ncbi request reprint Methods for determining the metabolism of alpha-linolenic acid in human subjects from intrinsically-labeled food
    Robert J Pawlosky
    Food Composition Laboratory, Beltsville, MD 20705, USA
    Forum Nutr 56:75-7. 2003
  7. ncbi request reprint Effects of beef- and fish-based diets on the kinetics of n-3 fatty acid metabolism in human subjects
    Robert J Pawlosky
    Food Composition Laboratory, Beltsville Human Nutrition Research Center, US Department of Agriculture, Beltsville, MD, USA
    Am J Clin Nutr 77:565-72. 2003
    ..Diets rich in 20- and 22-carbon PUFAs may inhibit desaturase expression or activity and decrease the synthesis of long-chain unsaturated fatty acids...
  8. ncbi request reprint Simultaneous quantitative determination of deuterium- and carbon-13-labeled essential fatty acids in rat plasma
    Yu Hong Lin
    Section of Nutritional Neuroscience, Laboratory of Membrane Biochemistry and Biophysics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892 9410, USA
    J Lipid Res 46:1974-82. 2005
    ..Thus, there appears to be little isotope effect for 2H5- versus 13C-U-labeled EFAs when the data are calculated using the conventional standard curves and corrected for endogenous fatty acid pool size and matrix effects...
  9. ncbi request reprint Compartmental analyses of plasma 13C- and 2H-labeled n-6 fatty acids arising from oral administrations of 13C-U-18:2n-6 and 2H5-20:3n-6 in newborn infants
    Robert J Pawlosky
    Laboratory of Metabolic Control, National Institutes on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, USA
    Pediatr Res 60:327-33. 2006
    ..2), respectively. Infants required additional 18:2n-6 and 20:4n-6 (mean: 1.2 g and 1.5 mg/kg/d) above predicted intake amounts to maintain plasma concentrations of 18:2n-6 and 20:4n-6, in order to spare FA from fat stores...
  10. ncbi request reprint Compartmental analyses of plasma n-3 essential fatty acids among male and female smokers and nonsmokers
    Robert J Pawlosky
    Laboratory of Metabolic Control, National Institutes on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA
    J Lipid Res 48:935-43. 2007
    ..03) that was greater compared with nonsmokers. Smoking increased the bioavailability of n-3 FAs from plasma, accelerated the fractional synthetic rates, and heightened the percent formation of some long-chain n-3 PUFAs in men and women...