Jae B Park

Summary

Affiliation: Agricultural Research Service
Country: USA

Publications

  1. ncbi request reprint Isolation and quantification of major chlorogenic acids in three major instant coffee brands and their potential effects on H2O2-induced mitochondrial membrane depolarization and apoptosis in PC-12 cells
    Jae B Park
    Diet, Genomics, and Immunology Laboratory, BHNRC, ARS, USDA, Bldg 307C, Rm 131, Beltsville, MD 20705, USA
    Food Funct 4:1632-8. 2013
  2. doi request reprint Synthesis, biological activities and bioavailability of moschamine, a safflomide-type phenylpropenoic acid amide found in Centaurea cyanus
    Jae B Park
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, US Department of Agriculture, Room 131, Building 307C, Beltsville, MD 20705, USA
    Nat Prod Res 26:1465-72. 2012
  3. doi request reprint Potential effects of lignan-enriched flaxseed powder on bodyweight, visceral fat, lipid profile, and blood pressure in rats
    Jae B Park
    USDA, ARS, BHNRC, Diet, Genomics, and Immunology Laboratory, Beltsville, MD 20705, United States
    Fitoterapia 83:941-6. 2012
  4. doi request reprint Safflomide increases the expression of adiponectin in vitro and in vivo: potential implication for hypoadiponectemia, visceral obesity, and insulin resistance
    Jae B Park
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center BHNRC, Agriculture Research Service ARS, United States Department of Agriculture USDA, Beltsville, Maryland 20705, United States
    J Agric Food Chem 60:4048-52. 2012
  5. doi request reprint Identification and quantification of a major anti-oxidant and anti-inflammatory phenolic compound found in basil, lemon thyme, mint, oregano, rosemary, sage, and thyme
    Jae B Park
    Diet, Genomics, and Immunology Laboratory, US Department of Agriculture, Beltsville, Maryland 20705, USA
    Int J Food Sci Nutr 62:577-84. 2011
  6. doi request reprint Protective effects of veskamide, enferamide, becatamide, and oretamide on H2O2-induced apoptosis of PC-12 cells
    Jae B Park
    Diet, Genomics, and Immunology Laboratory, Bldg 307C, Rm 131, BHNRC, ARS, USDA, Beltsville, MD 20705, USA
    Phytomedicine 18:843-7. 2011
  7. doi request reprint Isolation and characterization of N-feruloyltyramine as the P-selectin expression suppressor from garlic (Allium sativum)
    Jae B Park
    Diet, Genomics, and Immunology Laboratory, BHNRC, ARS, USDA, Beltsville, Maryland 20705, USA
    J Agric Food Chem 57:8868-72. 2009
  8. doi request reprint 5-Caffeoylquinic acid and caffeic acid orally administered suppress P-selectin expression on mouse platelets
    Jae B Park
    Diet, Genomics, and Immunology Laboratory, BHNRC, ARS, USDA, Beltsville, MD 20705, USA
    J Nutr Biochem 20:800-5. 2009
  9. doi request reprint Serotomide and safflomide modulate forskolin-stimulated cAMP formation via 5-HT1 receptor
    J B Park
    Diet, Genomics, and Immunology Laboratory, BHNRC, ARS, USDA, Beltsville, MD 20705, USA
    Phytomedicine 15:1093-8. 2008
  10. ncbi request reprint N-Caffeoyltyramine arrests growth of U937 and Jurkat cells by inhibiting protein tyrosine phosphorylation and inducing caspase-3
    Jae B Park
    Phytonutrients Laboratory, US Department of Agriculture, Building 307, Room 313, PL, BHNRC, ARS, Beltsville, MD 20705, USA
    Cancer Lett 202:161-71. 2003

Detail Information

Publications18

  1. ncbi request reprint Isolation and quantification of major chlorogenic acids in three major instant coffee brands and their potential effects on H2O2-induced mitochondrial membrane depolarization and apoptosis in PC-12 cells
    Jae B Park
    Diet, Genomics, and Immunology Laboratory, BHNRC, ARS, USDA, Bldg 307C, Rm 131, Beltsville, MD 20705, USA
    Food Funct 4:1632-8. 2013
    ....
  2. doi request reprint Synthesis, biological activities and bioavailability of moschamine, a safflomide-type phenylpropenoic acid amide found in Centaurea cyanus
    Jae B Park
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, US Department of Agriculture, Room 131, Building 307C, Beltsville, MD 20705, USA
    Nat Prod Res 26:1465-72. 2012
    ..012) and COX-II by 54% (p < 0.014), at the concentration of 0.1 µmol L⁻¹. The oral bioavailability of moschamine was also determined in mice...
  3. doi request reprint Potential effects of lignan-enriched flaxseed powder on bodyweight, visceral fat, lipid profile, and blood pressure in rats
    Jae B Park
    USDA, ARS, BHNRC, Diet, Genomics, and Immunology Laboratory, Beltsville, MD 20705, United States
    Fitoterapia 83:941-6. 2012
    ..05). These data suggest that the LEFP supplementation may provide beneficial effects such as the reduction of bodyweight and fat accumulation, the lipid profile improvement, and blood pressure control...
  4. doi request reprint Safflomide increases the expression of adiponectin in vitro and in vivo: potential implication for hypoadiponectemia, visceral obesity, and insulin resistance
    Jae B Park
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center BHNRC, Agriculture Research Service ARS, United States Department of Agriculture USDA, Beltsville, Maryland 20705, United States
    J Agric Food Chem 60:4048-52. 2012
    ..These data suggest that safflomide may have beneficial effects on obesity-related conditions, such as low adiponectin, visceral obesity, and insulin resistance...
  5. doi request reprint Identification and quantification of a major anti-oxidant and anti-inflammatory phenolic compound found in basil, lemon thyme, mint, oregano, rosemary, sage, and thyme
    Jae B Park
    Diet, Genomics, and Immunology Laboratory, US Department of Agriculture, Beltsville, Maryland 20705, USA
    Int J Food Sci Nutr 62:577-84. 2011
    ..In this study, the rosmarinic acid content of perilla was also determined and compared with those of the seven herbs...
  6. doi request reprint Protective effects of veskamide, enferamide, becatamide, and oretamide on H2O2-induced apoptosis of PC-12 cells
    Jae B Park
    Diet, Genomics, and Immunology Laboratory, Bldg 307C, Rm 131, BHNRC, ARS, USDA, Beltsville, MD 20705, USA
    Phytomedicine 18:843-7. 2011
    ....
  7. doi request reprint Isolation and characterization of N-feruloyltyramine as the P-selectin expression suppressor from garlic (Allium sativum)
    Jae B Park
    Diet, Genomics, and Immunology Laboratory, BHNRC, ARS, USDA, Beltsville, Maryland 20705, USA
    J Agric Food Chem 57:8868-72. 2009
    ..012) and 33% (P < 0.014), respectively. N-Feruloyltyramine is likely to inhibit COX enzymes, thereby suppressing P-selectin expression on platelets...
  8. doi request reprint 5-Caffeoylquinic acid and caffeic acid orally administered suppress P-selectin expression on mouse platelets
    Jae B Park
    Diet, Genomics, and Immunology Laboratory, BHNRC, ARS, USDA, Beltsville, MD 20705, USA
    J Nutr Biochem 20:800-5. 2009
    ..These data suggest that both 5-caffeoylquinic acid and caffeic acid orally administered can be absorbed and suppress P-selectin expression on mouse platelets...
  9. doi request reprint Serotomide and safflomide modulate forskolin-stimulated cAMP formation via 5-HT1 receptor
    J B Park
    Diet, Genomics, and Immunology Laboratory, BHNRC, ARS, USDA, Beltsville, MD 20705, USA
    Phytomedicine 15:1093-8. 2008
    ..All together the data indicate that serotomide and safflomide may be potent compounds that respectively act to activate and to block 5-HT1 receptors on OK cells...
  10. ncbi request reprint N-Caffeoyltyramine arrests growth of U937 and Jurkat cells by inhibiting protein tyrosine phosphorylation and inducing caspase-3
    Jae B Park
    Phytonutrients Laboratory, US Department of Agriculture, Building 307, Room 313, PL, BHNRC, ARS, Beltsville, MD 20705, USA
    Cancer Lett 202:161-71. 2003
    ..These data indicate that N-caffeoyltyramine is most potent compound, inducing cell death of the cancer cells by inhibiting protein tyrosine kinases and activating caspase-3 activity...
  11. ncbi request reprint Clovamide-type phenylpropenoic acid amides, N-coumaroyldopamine and N-caffeoyldopamine, inhibit platelet-leukocyte interactions via suppressing P-selectin expression
    Jae B Park
    Phytonutrients Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland 20705, USA
    J Pharmacol Exp Ther 317:813-9. 2006
    ..011) and 34 to 43% (P < 0.014), respectively. These data suggest that the clovamide-type phenylpropenoic acid amides are able to suppress platelet-leukocyte interactions via inhibiting P-selectin expression...
  12. ncbi request reprint Caffedymine from cocoa has COX inhibitory activity suppressing the expression of a platelet activation marker, P-selectin
    Jae B Park
    Phytonutrients Laboratory, Bldg 307C, Rm 131, BHNRC, ARS, U S Department of Agriculture, Beltsville, Maryland 20705, USA
    J Agric Food Chem 55:2171-5. 2007
    ..These data indicate that COX inhibition is likely to be another mechanism for caffedymine to inhibit P-selectin expression on platelets...
  13. doi request reprint Effects of typheramide and alfrutamide found in Allium species on cyclooxygenases and lipoxygenases
    Jae B Park
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, U S Department of Agriculture, Beltsville, Maryland 20705, USA
    J Med Food 14:226-31. 2011
    ..Altogether, the data suggest that typheramide and alfrutamide from garlic and green onions are likely to be significant inhibitors for COX 1 and 2 rather than 5- and 12-LOX...
  14. ncbi request reprint Synthesis of safflomide and its HPLC measurement in mouse plasma after oral administration
    Jae B Park
    Phytonutrients Laboratory, BHNRC, ARS, U S Department of Agriculture, Beltsville, MD 20705, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 852:398-402. 2007
    ..This HPLC method standardized with safflomide is the first reported method able to quantify the compound in standard and plasma samples with good detection limit and consistent reproducibility...
  15. ncbi request reprint Quantitation of clovamide-type phenylpropenoic acid amides in cells and plasma using high-performance liquid chromatography with a coulometric electrochemical detector
    Jae B Park
    Phytonutrients Laboratory, Building 307C, Room 131, BHNRC, ARS, USDA, Beltsville, Maryland 20705, USA
    J Agric Food Chem 53:8135-40. 2005
    ....
  16. ncbi request reprint N-coumaroyldopamine and N-caffeoyldopamine increase cAMP via beta 2-adrenoceptors in myelocytic U937 cells
    Jae B Park
    Phytonutrients Laboratory, BHNRC, ARS, USDA, 307C, Rm 131, Beltsville, Maryland 20705, USA
    FASEB J 19:497-502. 2005
    ..These results indicate that N-coumaroyldopamine and N-caffeoyldopamine are potent compounds able to increase cAMP via beta2-adrenoceptors in U937 cells, and may have potential effects on human health...
  17. ncbi request reprint Cloning, sequencing, and characterization of alternatively spliced glutaredoxin 1 cDNA and its genomic gene: chromosomal localization, mrna stability, and origin of pseudogenes
    Jae B Park
    Phytonutrients Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland 20770, USA
    J Biol Chem 280:10427-34. 2005
    ..These data indicate that Grx1(as) cDNA is an alternatively spliced human Grx1 cDNA and that the Grx1(as) 3'-untranslated region may have a role in stabilizing mRNA...
  18. ncbi request reprint Synthesis and characterization of N-coumaroyltyramine as a potent phytochemical which arrests human transformed cells via inhibiting protein tyrosine kinases
    Jae B Park
    Phytonutrients Laboratory, U S Department of Agriculture, Beltsville, Maryland 20705, USA
    Biochem Biophys Res Commun 292:1104-10. 2002
    ..This is the first report of the growth suppressing activity of N-coumaroyltyramine and its arrest of cells at the S phase of the cell cycle, possibly by inhibition of protein tyrosine kinases...