Kiran S Panickar

Summary

Affiliation: Agricultural Research Service
Country: USA

Publications

  1. ncbi Beneficial effects of herbs, spices and medicinal plants on the metabolic syndrome, brain and cognitive function
    Kiran S Panickar
    Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Cent Nerv Syst Agents Med Chem 13:13-29. 2013
  2. ncbi Effects of dietary polyphenols on neuroregulatory factors and pathways that mediate food intake and energy regulation in obesity
    Kiran S Panickar
    Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD, USA
    Mol Nutr Food Res 57:34-47. 2013
  3. ncbi A procyanidin type A trimer from cinnamon extract attenuates glial cell swelling and the reduction in glutamate uptake following ischemia-like injury in vitro
    K S Panickar
    United States Department of Agriculture, Agricultural Research Service, Beltsville Human Nutrition Research Center, Diet, Genomics and Immunology Laboratory, Beltsville, MD 20705, USA
    Neuroscience 202:87-98. 2012
  4. ncbi Mechanisms underlying the protective effects of myricetin and quercetin following oxygen-glucose deprivation-induced cell swelling and the reduction in glutamate uptake in glial cells
    K S Panickar
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, USA
    Neuroscience 183:1-14. 2011
  5. ncbi Corticorelin, a synthetic human corticotropin-releasing factor analog, for the treatment of peritumoral brain edema
    Kiran S Panickar
    US Department of Agriculture, Beltsville Human Nutrition Research Center, Diet, Genomics and Immunology Laboratory, Building 307C, Beltsville, MD 20705, USA
    Curr Opin Mol Ther 12:780-9. 2010
  6. ncbi Role of dietary polyphenols in attenuating brain edema and cell swelling in cerebral ischemia
    Kiran S Panickar
    Department of Agriculture, Diet, Genomics, and Immunology Laboratory, Agricultural Research Service, Beltsville Human Nutrition Research Center, Beltsville, MD 20705, USA
    Recent Pat CNS Drug Discov 5:99-108. 2010
  7. ncbi Green tea polyphenols attenuate glial swelling and mitochondrial dysfunction following oxygen-glucose deprivation in cultures
    Kiran S Panickar
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland 20705, USA
    Nutr Neurosci 12:105-13. 2009
  8. ncbi Cinnamon polyphenols attenuate cell swelling and mitochondrial dysfunction following oxygen-glucose deprivation in glial cells
    Kiran S Panickar
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, 10300 Baltimore Ave, Bldg 307C, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, USA
    Exp Neurol 216:420-7. 2009
  9. ncbi Overexpression of Cdk5 or non-phosphorylatable retinoblastoma protein protects septal neurons from oxygen-glucose deprivation
    Kiran S Panickar
    Department of Physiology and Biophysics, University of Miami Miller School of Medicine, Miami, FL 33101, USA
    Neurochem Res 33:1852-8. 2008
  10. ncbi Na-K-Cl cotransporter-1 in the mechanism of cell swelling in cultured astrocytes after fluid percussion injury
    Arumugam R Jayakumar
    Department of Pathology, University of Miami School of Medicine, Miami, FL 33101, USA
    J Neurochem 117:437-48. 2011

Detail Information

Publications14

  1. ncbi Beneficial effects of herbs, spices and medicinal plants on the metabolic syndrome, brain and cognitive function
    Kiran S Panickar
    Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Cent Nerv Syst Agents Med Chem 13:13-29. 2013
    ..This review evaluates the current evidence available for herbs/spices in potentially improving the metabolic syndrome, as well as their neuroprotective effects on the brain, and cognitive function in animal and human studies...
  2. ncbi Effects of dietary polyphenols on neuroregulatory factors and pathways that mediate food intake and energy regulation in obesity
    Kiran S Panickar
    Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD, USA
    Mol Nutr Food Res 57:34-47. 2013
    ..The potential role of polyphenols in influencing the neuroregulatory factors, the neural signaling pathways and/or the peripheral feedback mechanisms that modulate food intake will also be examined...
  3. ncbi A procyanidin type A trimer from cinnamon extract attenuates glial cell swelling and the reduction in glutamate uptake following ischemia-like injury in vitro
    K S Panickar
    United States Department of Agriculture, Agricultural Research Service, Beltsville Human Nutrition Research Center, Diet, Genomics and Immunology Laboratory, Beltsville, MD 20705, USA
    Neuroscience 202:87-98. 2012
    ..Thus, the effects of trimer 1 in attenuating the reduction in glutamate uptake are likely mediated through their action on the mitochondria...
  4. ncbi Mechanisms underlying the protective effects of myricetin and quercetin following oxygen-glucose deprivation-induced cell swelling and the reduction in glutamate uptake in glial cells
    K S Panickar
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, USA
    Neuroscience 183:1-14. 2011
    ..The differential effects of myricetin and quercetin on OGD-induced reduction on glutamate uptake may be due to their differential effects on mitochondria...
  5. ncbi Corticorelin, a synthetic human corticotropin-releasing factor analog, for the treatment of peritumoral brain edema
    Kiran S Panickar
    US Department of Agriculture, Beltsville Human Nutrition Research Center, Diet, Genomics and Immunology Laboratory, Building 307C, Beltsville, MD 20705, USA
    Curr Opin Mol Ther 12:780-9. 2010
    ..Nevertheless, corticorelin was reasonably well tolerated in patients and healthy volunteers, and may be a good candidate for reducing PBE and associated neural damage, as well as improving neurological symptoms...
  6. ncbi Role of dietary polyphenols in attenuating brain edema and cell swelling in cerebral ischemia
    Kiran S Panickar
    Department of Agriculture, Diet, Genomics, and Immunology Laboratory, Agricultural Research Service, Beltsville Human Nutrition Research Center, Beltsville, MD 20705, USA
    Recent Pat CNS Drug Discov 5:99-108. 2010
    ..A review of currently known mechanisms underlying edema/cell swelling will be undertaken and the potential of dietary polyphenols to reduce edema will be critically reviewed with the discussion of some recent patents...
  7. ncbi Green tea polyphenols attenuate glial swelling and mitochondrial dysfunction following oxygen-glucose deprivation in cultures
    Kiran S Panickar
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland 20705, USA
    Nutr Neurosci 12:105-13. 2009
    ..It appears that effects on cell swelling are mediated by the concerted action of more than one of the individual components of GTE...
  8. ncbi Cinnamon polyphenols attenuate cell swelling and mitochondrial dysfunction following oxygen-glucose deprivation in glial cells
    Kiran S Panickar
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, 10300 Baltimore Ave, Bldg 307C, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, USA
    Exp Neurol 216:420-7. 2009
    ..Our results show that CPE reduces OGD-induced cell swelling as well as the decline in DeltaPsi(m) in cultures and some of its protective effects may be through inhibiting the mPT...
  9. ncbi Overexpression of Cdk5 or non-phosphorylatable retinoblastoma protein protects septal neurons from oxygen-glucose deprivation
    Kiran S Panickar
    Department of Physiology and Biophysics, University of Miami Miller School of Medicine, Miami, FL 33101, USA
    Neurochem Res 33:1852-8. 2008
    ..Thus phosphorylation of the cell cycle regulator, Rb, contributes to death in OGD in septal neurons but Cdk5 can have a protective role...
  10. ncbi Na-K-Cl cotransporter-1 in the mechanism of cell swelling in cultured astrocytes after fluid percussion injury
    Arumugam R Jayakumar
    Department of Pathology, University of Miami School of Medicine, Miami, FL 33101, USA
    J Neurochem 117:437-48. 2011
    ....
  11. ncbi Cinnamon: potential role in the prevention of insulin resistance, metabolic syndrome, and type 2 diabetes
    Bolin Qin
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, United States Department of Agriculture, Agricultural Research Service, Beltsville, Maryland 20705 2350, USA
    J Diabetes Sci Technol 4:685-93. 2010
    ..In summary, components of cinnamon may be important in the alleviation and prevention of the signs and symptoms of metabolic syndrome, type 2 diabetes, and cardiovascular and related diseases...
  12. ncbi Trauma-induced cell swelling in cultured astrocytes
    Arumugam R Jayakumar
    Department of Pathology, University of Miami Miller School of Medicine, Miami, Florida 33101, USA
    J Neuropathol Exp Neurol 67:417-27. 2008
    ..These findings demonstrate that direct mechanical injury to cultured astrocytes brings about cell swelling, and that blockade of oxidative/nitrosative stress, mPT, and MAPKs significantly reduce such swelling...
  13. ncbi Effect of polyphenols on oxidative stress and mitochondrial dysfunction in neuronal death and brain edema in cerebral ischemia
    Kiran S Panickar
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, USA E mail
    Int J Mol Sci 12:8181-207. 2011
    ..A review of currently known mechanisms underlying neuronal death and edema/cell swelling will be undertaken and the potential of dietary polyphenols to reduce such neural damage will be critically reviewed...
  14. ncbi Astrocytes in cerebral ischemic injury: morphological and general considerations
    Kiran S Panickar
    Department of Pathology, University of Miami School of Medicine, Miami, Florida 33101, USA
    Glia 50:287-98. 2005
    ..Interactions with neurons, microglia, and endothelial cells are also considered. This article highlights the critical role of astrocytes in the CNS response to ischemic injury...