Kiran S Panickar

Summary

Affiliation: Agricultural Research Service
Country: USA

Publications

  1. ncbi request reprint Beneficial effects of herbs, spices and medicinal plants on the metabolic syndrome, brain and cognitive function
    Kiran S Panickar
    Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Cent Nerv Syst Agents Med Chem 13:13-29. 2013
  2. ncbi request reprint Dietary and plant polyphenols exert neuroprotective effects and improve cognitive function in cerebral ischemia
    Kiran S Panickar
    Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Recent Pat Food Nutr Agric 5:128-43. 2013
  3. doi request reprint Effects of dietary polyphenols on neuroregulatory factors and pathways that mediate food intake and energy regulation in obesity
    Kiran S Panickar
    Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD, USA
    Mol Nutr Food Res 57:34-47. 2013
  4. doi request reprint A procyanidin type A trimer from cinnamon extract attenuates glial cell swelling and the reduction in glutamate uptake following ischemia-like injury in vitro
    K S Panickar
    United States Department of Agriculture, Agricultural Research Service, Beltsville Human Nutrition Research Center, Diet, Genomics and Immunology Laboratory, Beltsville, MD 20705, USA
    Neuroscience 202:87-98. 2012
  5. doi request reprint Mechanisms underlying the protective effects of myricetin and quercetin following oxygen-glucose deprivation-induced cell swelling and the reduction in glutamate uptake in glial cells
    K S Panickar
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, USA
    Neuroscience 183:1-14. 2011
  6. ncbi request reprint Corticorelin, a synthetic human corticotropin-releasing factor analog, for the treatment of peritumoral brain edema
    Kiran S Panickar
    US Department of Agriculture, Beltsville Human Nutrition Research Center, Diet, Genomics and Immunology Laboratory, Building 307C, Beltsville, MD 20705, USA
    Curr Opin Mol Ther 12:780-9. 2010
  7. ncbi request reprint Role of dietary polyphenols in attenuating brain edema and cell swelling in cerebral ischemia
    Kiran S Panickar
    Department of Agriculture, Diet, Genomics, and Immunology Laboratory, Agricultural Research Service, Beltsville Human Nutrition Research Center, Beltsville, MD 20705, USA
    Recent Pat CNS Drug Discov 5:99-108. 2010
  8. doi request reprint Green tea polyphenols attenuate glial swelling and mitochondrial dysfunction following oxygen-glucose deprivation in cultures
    Kiran S Panickar
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland 20705, USA
    Nutr Neurosci 12:105-13. 2009
  9. doi request reprint Cinnamon polyphenols attenuate cell swelling and mitochondrial dysfunction following oxygen-glucose deprivation in glial cells
    Kiran S Panickar
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, 10300 Baltimore Ave, Bldg 307C, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, USA
    Exp Neurol 216:420-7. 2009
  10. doi request reprint Overexpression of Cdk5 or non-phosphorylatable retinoblastoma protein protects septal neurons from oxygen-glucose deprivation
    Kiran S Panickar
    Department of Physiology and Biophysics, University of Miami Miller School of Medicine, Miami, FL 33101, USA
    Neurochem Res 33:1852-8. 2008

Detail Information

Publications17

  1. ncbi request reprint Beneficial effects of herbs, spices and medicinal plants on the metabolic syndrome, brain and cognitive function
    Kiran S Panickar
    Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Cent Nerv Syst Agents Med Chem 13:13-29. 2013
    ..This review evaluates the current evidence available for herbs/spices in potentially improving the metabolic syndrome, as well as their neuroprotective effects on the brain, and cognitive function in animal and human studies...
  2. ncbi request reprint Dietary and plant polyphenols exert neuroprotective effects and improve cognitive function in cerebral ischemia
    Kiran S Panickar
    Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Recent Pat Food Nutr Agric 5:128-43. 2013
    ..In addition, the review will also examine available patents in nutrition and agriculture that relates to cerebral ischemic injury with an emphasis on plant polyphenols...
  3. doi request reprint Effects of dietary polyphenols on neuroregulatory factors and pathways that mediate food intake and energy regulation in obesity
    Kiran S Panickar
    Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD, USA
    Mol Nutr Food Res 57:34-47. 2013
    ..The potential role of polyphenols in influencing the neuroregulatory factors, the neural signaling pathways and/or the peripheral feedback mechanisms that modulate food intake will also be examined...
  4. doi request reprint A procyanidin type A trimer from cinnamon extract attenuates glial cell swelling and the reduction in glutamate uptake following ischemia-like injury in vitro
    K S Panickar
    United States Department of Agriculture, Agricultural Research Service, Beltsville Human Nutrition Research Center, Diet, Genomics and Immunology Laboratory, Beltsville, MD 20705, USA
    Neuroscience 202:87-98. 2012
    ..Thus, the effects of trimer 1 in attenuating the reduction in glutamate uptake are likely mediated through their action on the mitochondria...
  5. doi request reprint Mechanisms underlying the protective effects of myricetin and quercetin following oxygen-glucose deprivation-induced cell swelling and the reduction in glutamate uptake in glial cells
    K S Panickar
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, USA
    Neuroscience 183:1-14. 2011
    ..The differential effects of myricetin and quercetin on OGD-induced reduction on glutamate uptake may be due to their differential effects on mitochondria...
  6. ncbi request reprint Corticorelin, a synthetic human corticotropin-releasing factor analog, for the treatment of peritumoral brain edema
    Kiran S Panickar
    US Department of Agriculture, Beltsville Human Nutrition Research Center, Diet, Genomics and Immunology Laboratory, Building 307C, Beltsville, MD 20705, USA
    Curr Opin Mol Ther 12:780-9. 2010
    ..Nevertheless, corticorelin was reasonably well tolerated in patients and healthy volunteers, and may be a good candidate for reducing PBE and associated neural damage, as well as improving neurological symptoms...
  7. ncbi request reprint Role of dietary polyphenols in attenuating brain edema and cell swelling in cerebral ischemia
    Kiran S Panickar
    Department of Agriculture, Diet, Genomics, and Immunology Laboratory, Agricultural Research Service, Beltsville Human Nutrition Research Center, Beltsville, MD 20705, USA
    Recent Pat CNS Drug Discov 5:99-108. 2010
    ..A review of currently known mechanisms underlying edema/cell swelling will be undertaken and the potential of dietary polyphenols to reduce edema will be critically reviewed with the discussion of some recent patents...
  8. doi request reprint Green tea polyphenols attenuate glial swelling and mitochondrial dysfunction following oxygen-glucose deprivation in cultures
    Kiran S Panickar
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland 20705, USA
    Nutr Neurosci 12:105-13. 2009
    ..It appears that effects on cell swelling are mediated by the concerted action of more than one of the individual components of GTE...
  9. doi request reprint Cinnamon polyphenols attenuate cell swelling and mitochondrial dysfunction following oxygen-glucose deprivation in glial cells
    Kiran S Panickar
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, 10300 Baltimore Ave, Bldg 307C, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, USA
    Exp Neurol 216:420-7. 2009
    ..Our results show that CPE reduces OGD-induced cell swelling as well as the decline in DeltaPsi(m) in cultures and some of its protective effects may be through inhibiting the mPT...
  10. doi request reprint Overexpression of Cdk5 or non-phosphorylatable retinoblastoma protein protects septal neurons from oxygen-glucose deprivation
    Kiran S Panickar
    Department of Physiology and Biophysics, University of Miami Miller School of Medicine, Miami, FL 33101, USA
    Neurochem Res 33:1852-8. 2008
    ..Thus phosphorylation of the cell cycle regulator, Rb, contributes to death in OGD in septal neurons but Cdk5 can have a protective role...
  11. doi request reprint Na-K-Cl cotransporter-1 in the mechanism of cell swelling in cultured astrocytes after fluid percussion injury
    Arumugam R Jayakumar
    Department of Pathology, University of Miami School of Medicine, Miami, FL 33101, USA
    J Neurochem 117:437-48. 2011
    ....
  12. ncbi request reprint Cinnamon polyphenols attenuate the hydrogen peroxide-induced down regulation of S100β secretion by regulating sirtuin 1 in C6 rat glioma cells
    Bolin Qin
    IN Ingredients Inc, Columbia, TN 38401, USA 1 United States Department of Agriculture, Agricultural Research Service, Beltsville Human Nutrition Research Center, Diet, Genomics and Immunology Laboratory, Beltsville, MD 20705, USA Electronic address
    Life Sci 102:72-9. 2014
    ....
  13. pmc Cinnamon: potential role in the prevention of insulin resistance, metabolic syndrome, and type 2 diabetes
    Bolin Qin
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, United States Department of Agriculture, Agricultural Research Service, Beltsville, Maryland 20705 2350, USA
    J Diabetes Sci Technol 4:685-93. 2010
    ..In summary, components of cinnamon may be important in the alleviation and prevention of the signs and symptoms of metabolic syndrome, type 2 diabetes, and cardiovascular and related diseases...
  14. doi request reprint Trauma-induced cell swelling in cultured astrocytes
    Arumugam R Jayakumar
    Department of Pathology, University of Miami Miller School of Medicine, Miami, Florida 33101, USA
    J Neuropathol Exp Neurol 67:417-27. 2008
    ..These findings demonstrate that direct mechanical injury to cultured astrocytes brings about cell swelling, and that blockade of oxidative/nitrosative stress, mPT, and MAPKs significantly reduce such swelling...
  15. doi request reprint Cinnamon polyphenols regulate S100β, sirtuins, and neuroactive proteins in rat C6 glioma cells
    Bolin Qin
    Diet, Genomics and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, U S Department of Agriculture, Beltsville, MD, USA Integrity Nutraceuticals International, Spring Hill, TN, USA Electronic address
    Nutrition 30:210-7. 2014
    ..The aim of this study was to investigate the effects of an aqueous extract of cinnamon, high in type A polyphenols, on molecular targets in rat C6 glioma cells that underlie their protective effects...
  16. pmc Effect of polyphenols on oxidative stress and mitochondrial dysfunction in neuronal death and brain edema in cerebral ischemia
    Kiran S Panickar
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, USA E mail
    Int J Mol Sci 12:8181-207. 2011
    ..A review of currently known mechanisms underlying neuronal death and edema/cell swelling will be undertaken and the potential of dietary polyphenols to reduce such neural damage will be critically reviewed...
  17. ncbi request reprint Astrocytes in cerebral ischemic injury: morphological and general considerations
    Kiran S Panickar
    Department of Pathology, University of Miami School of Medicine, Miami, Florida 33101, USA
    Glia 50:287-98. 2005
    ..Interactions with neurons, microglia, and endothelial cells are also considered. This article highlights the critical role of astrocytes in the CNS response to ischemic injury...