Stuart B Krasnoff

Summary

Affiliation: Agricultural Research Service
Country: USA

Publications

  1. pmc Metacridamides A and B, macrocycles from conidia of the entomopathogenic fungus Metarhizium acridum
    Stuart B Krasnoff
    USDA ARS Biological IPM Research Unit, Ithaca, New York 14853, USA
    J Nat Prod 75:175-80. 2012
  2. ncbi request reprint Serinocyclins A and B, cyclic heptapeptides from Metarhizium anisopliae
    Stuart B Krasnoff
    USDA ARS Plant Protection Research Unit, Ithaca, NY 14853, USA
    J Nat Prod 70:1919-24. 2007
  3. ncbi request reprint Nitric oxide synthase inhibitors and nitric oxide donors modulate the biosynthesis of thaxtomin A, a nitrated phytotoxin produced by Streptomyces spp
    Michael J Wach
    Department of Plant Pathology, Cornell University, Ithaca, NY 14853, USA
    Nitric Oxide 12:46-53. 2005
  4. pmc Agrobacterium-mediated disruption of a nonribosomal peptide synthetase gene in the invertebrate pathogen Metarhizium anisopliae reveals a peptide spore factor
    Yong Sun Moon
    Boyce Thompson Institute for Plant Research, Ithaca, New York 14853, USA
    Appl Environ Microbiol 74:4366-80. 2008
  5. ncbi request reprint Chemistry and phytotoxicity of thaxtomin A alkyl ethers
    Stuart B Krasnoff
    Department of Plant Pathology, Cornell University, Ithaca, New York 14853, USA
    J Agric Food Chem 53:9446-51. 2005
  6. ncbi request reprint Effect of carbohydrates on the production of thaxtomin A by Streptomyces acidiscabies
    Michael J Wach
    Department of Plant Pathology, Cornell University, Ithaca, NY 14853, USA
    Arch Microbiol 188:81-8. 2007
  7. doi request reprint 4-Nitrotryptophan is a substrate for the non-ribosomal peptide synthetase TxtB in the thaxtomin A biosynthetic pathway
    Evan G Johnson
    Department of Plant Pathology and Plant Microbe Biology, Cornell University, Ithaca, NY 14853, USA
    Mol Microbiol 73:409-18. 2009
  8. pmc Pseudomonas syringae pv. tomato DC3000 CmaL (PSPTO4723), a DUF1330 family member, is needed to produce L-allo-isoleucine, a precursor for the phytotoxin coronatine
    Jay N Worley
    Department of Plant Pathology and Plant Microbe Biology, Cornell University, Ithaca, NY, USA
    J Bacteriol 195:287-96. 2013
  9. doi request reprint Genetic basis of destruxin production in the entomopathogen Metarhizium robertsii
    Bruno Giuliano Garisto Donzelli
    Biological Integrated Pest Management Research Unit, Robert W Holley Center for Agriculture and Health, USDA ARS, 538 Tower Road, Ithaca, NY 14853, USA
    Curr Genet 58:105-16. 2012
  10. ncbi request reprint Identification of a hybrid PKS-NRPS required for the biosynthesis of NG-391 in Metarhizium robertsii
    Bruno Giuliano Garisto Donzelli
    Biological Integrated Pest Management Research Unit, Robert W Holley Center for Agriculture and Health, USDA ARS, Tower Road, Ithaca, NY 14853, USA
    Curr Genet 56:151-62. 2010

Collaborators

Detail Information

Publications18

  1. pmc Metacridamides A and B, macrocycles from conidia of the entomopathogenic fungus Metarhizium acridum
    Stuart B Krasnoff
    USDA ARS Biological IPM Research Unit, Ithaca, New York 14853, USA
    J Nat Prod 75:175-80. 2012
    ..In addition, metacridamide B had an IC₅₀ of 18.2 μM against HepG2/C3A, although it was inactive at 100 μM against Caco-2 and MCF-7. Neither analogue showed antimicrobial, phytotoxic, or insecticidal activity...
  2. ncbi request reprint Serinocyclins A and B, cyclic heptapeptides from Metarhizium anisopliae
    Stuart B Krasnoff
    USDA ARS Plant Protection Research Unit, Ithaca, NY 14853, USA
    J Nat Prod 70:1919-24. 2007
    ..Serinocyclin A produced a sublethal locomotory defect in mosquito larvae at an EC 50 of 59 ppm...
  3. ncbi request reprint Nitric oxide synthase inhibitors and nitric oxide donors modulate the biosynthesis of thaxtomin A, a nitrated phytotoxin produced by Streptomyces spp
    Michael J Wach
    Department of Plant Pathology, Cornell University, Ithaca, NY 14853, USA
    Nitric Oxide 12:46-53. 2005
    ..Our data suggest that bacterial nitric oxide synthases may, at least in part, produce NO for biosynthetic purposes, rather than for cellular signaling, as they do in mammals...
  4. pmc Agrobacterium-mediated disruption of a nonribosomal peptide synthetase gene in the invertebrate pathogen Metarhizium anisopliae reveals a peptide spore factor
    Yong Sun Moon
    Boyce Thompson Institute for Plant Research, Ithaca, New York 14853, USA
    Appl Environ Microbiol 74:4366-80. 2008
    ..This is the first report of targeted disruption of a secondary metabolite gene in M. anisopliae, which revealed a novel cyclic peptide spore factor...
  5. ncbi request reprint Chemistry and phytotoxicity of thaxtomin A alkyl ethers
    Stuart B Krasnoff
    Department of Plant Pathology, Cornell University, Ithaca, New York 14853, USA
    J Agric Food Chem 53:9446-51. 2005
    ..Among the 11S,14R-configured compounds, potency decreased with an increasing size of the substituted alkoxy group...
  6. ncbi request reprint Effect of carbohydrates on the production of thaxtomin A by Streptomyces acidiscabies
    Michael J Wach
    Department of Plant Pathology, Cornell University, Ithaca, NY 14853, USA
    Arch Microbiol 188:81-8. 2007
    ..The data indicate that complex carbohydrates may act as environmental signals to plant pathogenic Streptomyces, allowing production of thaxtomin and enabling bacteria to colonize its host...
  7. doi request reprint 4-Nitrotryptophan is a substrate for the non-ribosomal peptide synthetase TxtB in the thaxtomin A biosynthetic pathway
    Evan G Johnson
    Department of Plant Pathology and Plant Microbe Biology, Cornell University, Ithaca, NY 14853, USA
    Mol Microbiol 73:409-18. 2009
    ....
  8. pmc Pseudomonas syringae pv. tomato DC3000 CmaL (PSPTO4723), a DUF1330 family member, is needed to produce L-allo-isoleucine, a precursor for the phytotoxin coronatine
    Jay N Worley
    Department of Plant Pathology and Plant Microbe Biology, Cornell University, Ithaca, NY, USA
    J Bacteriol 195:287-96. 2013
    ..This characterization of CmaL identifies a critical missing factor in coronatine production and provides a foundation for further investigation of a member of the widespread DUF1330 protein family...
  9. doi request reprint Genetic basis of destruxin production in the entomopathogen Metarhizium robertsii
    Bruno Giuliano Garisto Donzelli
    Biological Integrated Pest Management Research Unit, Robert W Holley Center for Agriculture and Health, USDA ARS, 538 Tower Road, Ithaca, NY 14853, USA
    Curr Genet 58:105-16. 2012
    ..The DXS mutants exhibited no other detectable changes in morphology and development...
  10. ncbi request reprint Identification of a hybrid PKS-NRPS required for the biosynthesis of NG-391 in Metarhizium robertsii
    Bruno Giuliano Garisto Donzelli
    Biological Integrated Pest Management Research Unit, Robert W Holley Center for Agriculture and Health, USDA ARS, Tower Road, Ithaca, NY 14853, USA
    Curr Genet 56:151-62. 2010
    ..exigua host. The use of an NGS1 promoter-GFP reporter fusion showed that during in vitro growth in still broth cultures, NGS1 expression is restricted to the early exponential phase and is affected by M. robertsii cell density...
  11. doi request reprint Phytotoxicity of antofine from invasive swallow-worts
    Donna M Gibson
    USDA, Agricultural Research Service, Biological Integrated Pest Management Research Unit, Robert W Holley Center for Agriculture and Health, Tower Road, Ithaca, NY 14853, USA
    J Chem Ecol 37:871-9. 2011
    ....
  12. pmc Intracellular siderophores are essential for ascomycete sexual development in heterothallic Cochliobolus heterostrophus and homothallic Gibberella zeae
    Shinichi Oide
    Department of Plant Pathology and Plant Microbe Biology, 334 Plant Science Bldg, Cornell University, Ithaca, NY 14853, USA
    Eukaryot Cell 6:1339-53. 2007
    ..Overall, these data demonstrate that iron and intracellular siderophores are essential for successful sexual development of the heterothallic ascomycete C. heterostrophus and the homothallic ascomycete G. zeae...
  13. ncbi request reprint Production of mutagenic metabolites by Metarhizium anisopliae
    Stuart B Krasnoff
    USDA ARS Plant Protection Research Unit, Tower Road, Ithaca, New York 14853, USA
    J Agric Food Chem 54:7083-8. 2006
    ..The impact of these findings on the use of M. anisopliae as a biocontrol agent is currently unknown and requires further investigation...
  14. ncbi request reprint Cicadapeptins I and II: new Aib-containing peptides from the entomopathogenic fungus Cordyceps heteropoda
    Stuart B Krasnoff
    Department of Plant Pathology, Cornell University, Ithaca, New York 14853, USA
    J Nat Prod 68:50-5. 2005
    ..ROESY data indicated that the cicadapeptins adopt a helical conformation. Cicadapeptins I and II displayed antibacterial activity and limited antifungal activity...
  15. ncbi request reprint Kaempferol in red and pinto bean seed (Phaseolus vulgaris L.) coats inhibits iron bioavailability using an in vitro digestion/human Caco-2 cell model
    Ying Hu
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    J Agric Food Chem 54:9254-61. 2006
    ..Results comparing the inhibitory effects of kaempferol, quercitrin, and astragalin on iron bioavailability suggest that the 3',4'-dihydroxy group on the B-ring in flavonoids contributes to the lower iron bioavailability...
  16. ncbi request reprint Nitration of a peptide phytotoxin by bacterial nitric oxide synthase
    Johan A Kers
    Department of Plant Pathology, Cornell University, Ithaca, New York 14853, USA
    Nature 429:79-82. 2004
    ..Here we show that the primary function of Streptomyces NOS is radically different from that of mammalian NOS. Surprisingly, mammalian NO signalling and bacterial biosynthetic nitration share an evolutionary origin...
  17. ncbi request reprint Induction of hypericins and hyperforins in Hypericum perforatum in response to damage by herbivores
    Tara M Sirvent
    Department of Plant Pathology, Cornell University, Ithaca, New York, USA
    J Chem Ecol 29:2667-81. 2003
    ..Although the leaf damage index of the specialist feeding was 2.7 times greater, C. quadrigemina had little effect on H. perforatum chemical defenses in response to feeding damage in comparison to generalist feeding...
  18. ncbi request reprint Differential analysis of 2D NMR spectra: new natural products from a pilot-scale fungal extract library
    Frank C Schroeder
    Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA
    Angew Chem Int Ed Engl 46:901-4. 2007