Affiliation: Agricultural Research Service
- On the isolation of polychlorinated dibenzo-p-dioxins and furans from serum samples using immunoaffinity chromatography prior to high-resolution gas chromatography-mass spectrometryJ K Huwe
USDA, ARS, Biosciences Research Laboratory, Fargo, ND 58105, USA
J Chromatogr B Biomed Sci Appl 757:285-93. 2001..Dioxin-like polychlorinated biphenyls (PCBs) were not recognized by this antibody column. Compared to conventional dioxin cleanup methods, IAC decreased solvent usage by 1.5 l/sample and took only 2 h to process a sample for analysis...
- Accumulation, whole-body depletion, and debromination of decabromodiphenyl ether in male sprague-dawley rats following dietary exposureJanice K Huwe
Biosciences Research Laboratory, ARS, USDA, P O Box 5674, University Station, Fargo, North Dakota 58105 5647, USA
Environ Sci Technol 41:2371-7. 2007....
- Bioavailability and mass balance studies of a commercial pentabromodiphenyl ether mixture in male Sprague-Dawley ratsJanice Huwe
USDA, ARS, Biosciences Research Laboratory, P O Box 5674, University Station, Fargo, ND 58105 5647, USA
Chemosphere 66:259-66. 2007....
- Polychlorinated dioxins, furans, and biphenyls, and polybrominated diphenyl ethers in a U.S. meat market basket and estimates of dietary intakeJanice K Huwe
Biosciences Research Laboratory, USDA ARS, PO Box 5674 University Station, Fargo, North Dakota 58105, USA
Environ Sci Technol 39:5606-11. 2005..3-16.0 pg TEQ and 14.9-44.7 ng of PBDEs/d or 0.1-0.3 pg TEQ and 0.3-0.5 (ng of PBDEs/kg of body mass)/d for an average individual, similar to intakes in other countries...
- Laboratory and on-farm studies on the bioaccumulation and elimination of dioxins from a contaminated mineral supplement fed to dairy cowsJanice K Huwe
Biosciences Research Laboratory, ARS, U S Department of Agriculture, P O Box 5674 University Station, Fargo, North Dakota 58105 5674, USA
J Agric Food Chem 53:2362-70. 2005..It appeared that although the dioxins from the mineral supplements have the potential to bioaccumulate, dilution into the total diet was sufficient to prevent a significant rise in the dioxin concentrations in the milk at these farms...
- Levels of polychlorinated dibenzo-p-dioxins and dibenzofurans in cattle raised at agricultural research facilities across the USA and the influence of pentachlorophenol-treated woodJ K Huwe
USDA, ARS, Biosciences Research Laboratory, PO Box 5674 Fargo, ND 58105 5674, USA
Food Addit Contam 21:182-94. 2004..The largest contributors to the median toxic equivalencies were 1,2,3,7,8-PeCDD (40%) and 1,2,3,6,7,8-HxCDD (16%). No clear geographical trends emerged from the data...
- Analysis of mono- to deca-brominated diphenyl ethers in chickens at the part per billion levelJanice K Huwe
USDA, ARS, Biosciences Research Laboratory, University Station, Fargo, ND 58105 5674, USA
Chemosphere 46:635-40. 2002..The PBDE pattern was also different from other samples reported; penta-BDEs rather than tetra-BDEs were the most prominent congeners...
- Dioxins in food: a modern agricultural perspectiveJanice K Huwe
Biosciences Research Laboratory, Agricultural Research Service, U S Department of Agriculture, P O Box 5674, Fargo, North Dakota 58105, USA
J Agric Food Chem 50:1739-50. 2002..Research areas in agriculture where data and experimental results are scarce or nonexistent are also pointed out...
- Survey of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and non-ortho-polychlorinated biphenyls in U.S. meat and poultry, 2007-2008: effect of new toxic equivalency factors on toxic equivalency levels, patterns, and temporal trendsJanice Huwe
Biosciences Research Laboratory, Agricultural Research Service, US Department of Agriculture, Fargo, North Dakota 58105, USA
J Agric Food Chem 57:11194-200. 2009..Several samples from the 2008 survey with the highest TEQ values are undergoing follow-up investigations to determine possible sources that may be contributing to these levels...
- Concentrations of PCDD/PCDFs and PCBs in spent foundry sandsRobert S Dungan
USDA Agricultural Research Service, Northwest Irrigation and Soils Research Laboratory, Kimberly, ID 83341, USA
Chemosphere 75:1232-5. 2009..The total TEQ (toxicity equivalent) concentrations ranged from 0.01 to 3.13 ng TEQ kg(-1), with an average concentration of 0.58 ng TEQ kg(-1). These concentrations are within the range of natural background in soils...
- Metabolism of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) in chickensHeldur Hakk
Biosciences Research Laboratory, Agricultural Research Service, U S Department of Agriculture, 1605 Albrecht Boulevard, Fargo, North Dakota 58105 5674, USA
J Agric Food Chem 58:8757-62. 2010..The present results suggest that trimming the fat and skin from chicken would substantially reduce human exposure to PBDEs during the consumption of chicken...
- Comparative absorption and bioaccumulation of polybrominated diphenyl ethers following ingestion via dust and oil in male ratsJanice K Huwe
United States Department of Agriculture, Agricultural Research Service Biosciences Research Laboratory, Fargo, North Dakota 58105, USA
Environ Sci Technol 42:2694-700. 2008..The present study shows that PBDEs in dust are readily bioavailable and are biologically active, as indicated by increased transcription of hepatic enzymes...
- Effect of nitroethane, dimethyl-2-nitroglutarate and 2-nitro-methyl-propionate on ruminal methane production and hydrogen balance in vitroRobin C Anderson
United States Department of Agriculture Agricultural Research Service, Southern Plains Agricultural Research Center, Food and Feed Safety Research Unit, 2881 F and B Road, College Station, Texas 77845 USA
Bioresour Technol 101:5345-9. 2010..05) than non-treated controls. Quantification of fermentation end-products produced and H(2) balance estimates indicate that fermentation efficiencies were not compromised by the nitro-treatments...
- Tissue distribution of polybrominated diphenyl ethers in male rats and implications for biomonitoringJanice K Huwe
USDA, ARS Biosciences Research Laboratory, Fargo, North Dakota 58105, USA
Environ Sci Technol 42:7018-24. 2008..Plasma was the best matrix for detection of the higher brominated congeners (especially BDE-209), although on a lipid-weight basis tended to overestimate the total body burdens...
- Novel and Distinct Metabolites Identified Following a Single Oral Dose of α- or γ-Hexabromocyclododecane in MiceHeldur Hakk
Agriculture Research Service, U S Department of Agriculture, 1605 Albrecht Boulevard, Biosciences Research Laboratory, Fargo, North Dakota 58102 2765, United States
Environ Sci Technol 46:13494-503. 2012..The distinct metabolic products identified in this study have the potential to aid in the identification of stereoisomer-specific HBCD exposures in future biomonitoring studies...
- Evaluation of automated direct sample introduction with comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry for the screening analysis of dioxins in fish oilEunha Hoh
US Department of Agriculture, Agricultural Research Service, Eastern Regional Research Center, 600 East Mermaid Lane, Wyndmoor, PA 19038, USA
J Chromatogr A 1201:69-77. 2008..Acceptable recoveries for nearly all analytes at three different spiking levels in fish oil samples were achieved with good repeatability...
- In utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure: effects on fetal and adult cardiac gene expression and adult cardiac and renal morphologyAndrea C Aragon
College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, USA
Toxicol Sci 101:321-30. 2008..These results demonstrate that in utero and lactational TCDD exposures alter cardiac gene expression and cardiac and renal morphology in adulthood, which may increase the susceptibility to cardiovascular dysfunction...