Wayne Chris Hawkes

Summary

Affiliation: Agricultural Research Service
Country: USA

Publications

  1. ncbi Delayed cell cycle progression in selenoprotein W-depleted cells is regulated by a mitogen-activated protein kinase kinase 4-p38/c-Jun NH2-terminal kinase-p53 pathway
    Wayne Chris Hawkes
    Western Human Nutrition Research Center, United States Department of Agriculture, Agricultural Research Service, University of California, Davis, California 95616, USA
    J Biol Chem 287:27371-9. 2012
  2. ncbi Delayed cell cycle progression from SEPW1 depletion is p53- and p21-dependent in MCF-7 breast cancer cells
    Wayne Chris Hawkes
    USDA Agricultural Research Service, Western Human Nutrition Research Center, University of California at Davis, 430 West Health Science Drive, Davis, CA 95616, USA
    Biochem Biophys Res Commun 413:36-40. 2011
  3. ncbi Selenoprotein W depletion induces a p53- and p21-dependent delay in cell cycle progression in RWPE-1 prostate epithelial cells
    Wayne Chris Hawkes
    USDA Agricultural Research Service, Western Human Nutrition Research Center, University of California at Davis, Davis, California 95616, USA
    J Cell Biochem 113:61-9. 2012
  4. ncbi Regulation of redox signaling by selenoproteins
    Wayne Chris Hawkes
    Western Human Nutrition Research Center, University of California at Davis, USA
    Biol Trace Elem Res 134:235-51. 2010
  5. ncbi The effect of selenium supplementation on DTH skin responses in healthy North American men
    Wayne Chris Hawkes
    United States Department of Agriculture, Agricultural Research Service, Western Human Nutrition Research Center, University of California at Davis, 430 West Health Sciences Drive, Davis, CA 95616, USA
    J Trace Elem Med Biol 23:272-80. 2009
  6. ncbi Selenoprotein W modulates control of cell cycle entry
    Wayne Chris Hawkes
    USDA Agricultural Research Service, Western Human Nutrition Research Center, University of California at Davis, Davis, CA, USA
    Biol Trace Elem Res 131:229-44. 2009
  7. ncbi Selenium supplementation does not affect testicular selenium status or semen quality in North American men
    Wayne Chris Hawkes
    Western Human Nutrition Research Center, US Department of Agriculture, Agricultural Research Service, University of California, Davis, California 95616, USA
    J Androl 30:525-33. 2009
  8. ncbi Selenium supplementation does not improve vascular responsiveness in healthy North American men
    Wayne Chris Hawkes
    USDA ARS Western Human Nutrition Research Center, University of California, Davis, CA 95616, USA
    Am J Physiol Heart Circ Physiol 296:H256-62. 2009
  9. ncbi High-selenium yeast supplementation in free-living North American men: no effect on thyroid hormone metabolism or body composition
    Wayne Chris Hawkes
    Western Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, University of California at Davis, 430 West Health Sciences Drive, Davis, CA 95616, USA
    J Trace Elem Med Biol 22:131-42. 2008
  10. ncbi Response of selenium status indicators to supplementation of healthy North American men with high-selenium yeast
    Wayne Chris Hawkes
    Agricultural Research Service, United States Department of Agriculture, University of California at Davis, Davis, CA 95616, USA
    Biol Trace Elem Res 122:107-21. 2008

Detail Information

Publications14

  1. ncbi Delayed cell cycle progression in selenoprotein W-depleted cells is regulated by a mitogen-activated protein kinase kinase 4-p38/c-Jun NH2-terminal kinase-p53 pathway
    Wayne Chris Hawkes
    Western Human Nutrition Research Center, United States Department of Agriculture, Agricultural Research Service, University of California, Davis, California 95616, USA
    J Biol Chem 287:27371-9. 2012
    ..These results imply that SEPW1 silencing increases MKK4, which activates p38γ, p38δ, and JNK2 to phosphorylate p53 on Ser-33 and cause a transient G(1) arrest...
  2. ncbi Delayed cell cycle progression from SEPW1 depletion is p53- and p21-dependent in MCF-7 breast cancer cells
    Wayne Chris Hawkes
    USDA Agricultural Research Service, Western Human Nutrition Research Center, University of California at Davis, 430 West Health Science Drive, Davis, CA 95616, USA
    Biochem Biophys Res Commun 413:36-40. 2011
    ..More work is needed to identify the mechanism by which SEPW1 regulates phosphorylation of Ser-33 and the kinase or phosphatase enzymes involved...
  3. ncbi Selenoprotein W depletion induces a p53- and p21-dependent delay in cell cycle progression in RWPE-1 prostate epithelial cells
    Wayne Chris Hawkes
    USDA Agricultural Research Service, Western Human Nutrition Research Center, University of California at Davis, Davis, California 95616, USA
    J Cell Biochem 113:61-9. 2012
    ..More research is required to identify the function of SEPW1 and how it affects stability of p53...
  4. ncbi Regulation of redox signaling by selenoproteins
    Wayne Chris Hawkes
    Western Human Nutrition Research Center, University of California at Davis, USA
    Biol Trace Elem Res 134:235-51. 2010
    ..Recent evidence suggests selenoprotein W and the six other small thioredoxin-like mammalian selenoproteins may serve to transduce hydrogen peroxide signals into regulatory disulfide bonds in specific target proteins...
  5. ncbi The effect of selenium supplementation on DTH skin responses in healthy North American men
    Wayne Chris Hawkes
    United States Department of Agriculture, Agricultural Research Service, Western Human Nutrition Research Center, University of California at Davis, 430 West Health Sciences Drive, Davis, CA 95616, USA
    J Trace Elem Med Biol 23:272-80. 2009
    ..These results suggest that Se plays a role in immunotolerization, a cell-mediated process involved in many aspects of immune function...
  6. ncbi Selenoprotein W modulates control of cell cycle entry
    Wayne Chris Hawkes
    USDA Agricultural Research Service, Western Human Nutrition Research Center, University of California at Davis, Davis, CA, USA
    Biol Trace Elem Res 131:229-44. 2009
    ..These results suggest that SEPW1 and the G1/S transition are physiological targets of Se in breast and prostate epithelial cells...
  7. ncbi Selenium supplementation does not affect testicular selenium status or semen quality in North American men
    Wayne Chris Hawkes
    Western Human Nutrition Research Center, US Department of Agriculture, Agricultural Research Service, University of California, Davis, California 95616, USA
    J Androl 30:525-33. 2009
    ..These results are consistent with animal studies showing the Se status of testes to be unresponsive to dietary Se intake...
  8. ncbi Selenium supplementation does not improve vascular responsiveness in healthy North American men
    Wayne Chris Hawkes
    USDA ARS Western Human Nutrition Research Center, University of California, Davis, CA 95616, USA
    Am J Physiol Heart Circ Physiol 296:H256-62. 2009
    ..This study indicates that selenium supplementation is not likely to improve endothelial function or peripheral arterial responsiveness in healthy North American men receiving adequate selenium from their diets...
  9. ncbi High-selenium yeast supplementation in free-living North American men: no effect on thyroid hormone metabolism or body composition
    Wayne Chris Hawkes
    Western Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, University of California at Davis, 430 West Health Sciences Drive, Davis, CA 95616, USA
    J Trace Elem Med Biol 22:131-42. 2008
    ....
  10. ncbi Response of selenium status indicators to supplementation of healthy North American men with high-selenium yeast
    Wayne Chris Hawkes
    Agricultural Research Service, United States Department of Agriculture, University of California at Davis, Davis, CA 95616, USA
    Biol Trace Elem Res 122:107-21. 2008
    ..The absorption, distribution, and excretion of selenium from high-Se yeast were similar to selenium in foods...
  11. ncbi Dietary selenium intake modulates thyroid hormone and energy metabolism in men
    Wayne Chris Hawkes
    U S Department of Agriculture, Agricultural Research Service, Western Human Nutrition Research Center and Department of Nutrition, University of California at Davis, Davis, CA, USA
    J Nutr 133:3443-8. 2003
    ..Increases of serum T3 and serum triacylglycerol accompanied by losses of body fat suggest that a subclinical hyperthyroid response was induced in the low selenium group, leading to body weight decreases...
  12. ncbi Absorption, distribution and excretion of selenium from beef and rice in healthy North American men
    Wayne Chris Hawkes
    U S Department of Agriculture, Agricultural Research Service, Western Human Nutrition Research Center and Department of Nutrition, University of California at Davis, Davis, CA, USA
    J Nutr 133:3434-42. 2003
    ..Fecal excretion decreased by half, representing an important but previously underappreciated adaptation to selenium restriction...
  13. ncbi Plasma selenium decrease during pregnancy is associated with glucose intolerance
    Wayne Chris Hawkes
    United States Department of Agriculture, Agricultural Research Service, Western Human Nutrition Research Center and Department of Nutrition, University of California at Davis, One Shields Avenue, Davis, CA, USA
    Biol Trace Elem Res 100:19-29. 2004
    ....
  14. ncbi Association of glutathione peroxidase activity with insulin resistance and dietary fat intake during normal pregnancy
    Wayne Chris Hawkes
    J Clin Endocrinol Metab 89:4772-3; author reply 4773-4. 2004