Research Topics
Species | G J HausmanSummaryAffiliation: Agricultural Research Service Country: USA Publications
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Publications
Expression of genes for interleukins, neuropeptides, growth hormone receptor, and leptin receptor in adipose tissue from growing broiler chickensG J Hausman
Poultry Processing and Swine Physiology Research, Agricultural Research Service, USDA, Athens, GA 30605, USA
Domest Anim Endocrinol 43:260-3. 2012..This is a unique exhibition of age-related changes in cytokine gene expression in chicken adipose tissue. Future studies are needed to elucidate the role of adipose tissue cytokines in growth and, possibly, disease resistance...- Meat Science and Muscle Biology Symposium: the influence of extracellular matrix on intramuscular and extramuscular adipogenesisG J Hausman
Poultry Processing and Swine Physiology Research, ARS, Richard B Russell Research Center, USDA, Athens, GA 30605, USA
J Anim Sci 90:942-9. 2012..Possibly, MMP and other proteases regulate turnover of key adipocyte ECM proteins that are involved in the regulation of preadipocyte proliferation and differentiation... 
Patterns of gene expression in pig adipose tissue: transforming growth factors, interferons, interleukins, and apolipoproteinsG J Hausman
USDA ARS, Russell Agricultural Research Center, Athens, GA, USA
J Anim Sci 85:2445-56. 2007..These studies demonstrate that expression of major cytokine and apolipoprotein genes in pig adipose tissue are not influenced by age in growing pigs but may be influenced by location or depot...- Patterns of gene expression in pig adipose tissue: insulin-like growth factor system proteins, neuropeptide Y (NPY), NPY receptors, neurotrophic factors and other secreted factorsG J Hausman
United States Department of Agriculture, Agricultural Research Service, Richard B Russell Agricultural Research Center, 950 College Station Road, Athens, GA 30605, USA
Domest Anim Endocrinol 35:24-34. 2008..Many other regulatory factors were not influenced by age in growing pigs but may be influenced by location or depot... - The influence of thiazolidinediones on adipogenesis in vitro and in vivo: potential modifiers of intramuscular adipose tissue deposition in meat animalsG J Hausman
USDA, ARS, APRU, Athens, GA 30605, USA
J Anim Sci 86:E236-43. 2008..Although timing of treatment with TZD needs to be optimized, evidence suggests these compounds may enhance marbling deposition in swine... - Adipose tissue and the reproductive axis: biological aspectsG J Hausman
USDA ARS, Richard B Russell Agriculture Research Center, Athens, GA, USA
Endocr Dev 19:31-44. 2010..Although leptin is identified as a putative signal that links metabolic status and neuroendocrine control of reproduction, other adipocyte protein products may play key roles in regulating the reproductive axisin the pig... - Recruitment and differentiation of intramuscular preadipocytes in stromal-vascular cell cultures derived from neonatal pig semitendinosus musclesG J Hausman
USDA ARS, Richard B Russell Agricultural Research Center, Animal Physiology Research Unit, Athens, GA 30605 2720, USA
J Anim Sci 82:429-37. 2004..These studies indicate that muscle-SV cultures are characterized by a low number of adipocytes under basal conditions and a low number of glucocorticoid-responsive preadipocytes... - The expression of cyclin D1 during adipogenesis in pig primary stromal-vascular culturesH S Kim
Department of Foods and Nutrition, University of Georgia, Athens, Georgia 30602, USA
Obes Res 9:572-8. 2001..In addition, cyclin D1 is absent from lipid-filled fetal adipose cells in vivo, where insulin levels are very low. The activity of cyclin D1 in differentiated adipocytes may be directed toward proteins outside of the cell cycle... - Secreted proteins and genes in fetal and neonatal pig adipose tissue and stromal-vascular cellsG J Hausman
USDA ARS, Russell Agricultural Research Center, Athens, GA 30604, USA
J Anim Sci 84:1666-81. 2006..These studies demonstrate, for the first time, the expression of several major secreted proteins in pig adipose tissue that may influence local and central metabolism and growth... - The influence of dexamethasone and insulin on expression of CCAAT/enhancer binding protein isoforms during preadipocyte differentiation in porcine stromal-vascular cell cultures: evidence for very early expression of C/EBPalphaG J Hausman
Richard B Russell Research Center, ARS, USDA, Athens, GA 30604 5677, USA
J Anim Sci 78:1227-35. 2000..These results indicate that coupling or integration of preadipocyte recruitment with C/EBPalpha expression may be a critical step in glucocorticoid-induced adipogenesis... - The biology of white adipocyte proliferationD B Hausman
Department of Foods and Nutrition, 263 Dawson Hall, University of Georgia, Athens, GA 30602, USA
Obes Rev 2:239-54. 2001..Both in vivo and in vitro studies are needed to understand the complex, interacting physiological mechanisms by which growth of this important organ is regulated... - Gene expression in the brain-pituitary adipose tissue axis and luteinising hormone secretion during pubertal development in the giltC R Barb
Animal Physiology Research Unit, USDA ARS, Richard B Russell Agriculture Research Center, PO Box 5677, Athens, GA 30604, USA
Soc Reprod Fertil Suppl 62:33-44. 2006.... - Biology of leptin in the pigC R Barb
USDA ARS, Animal Physiology Unit, Russell Research Center, P O Box 5677, Athens, GA 30604 5677, USA
Domest Anim Endocrinol 21:297-317. 2001.... - Dexamethasone induced preadipocyte recruitment and expression of CCAAT/enhancing binding protein alpha and peroxisome proliferator activated receptor-gamma proteins in porcine stromal-vascular (S-V) cell cultures obtained before and after the onset of fetG J Hausman
USDA ARS, Richard B Russell Agricultural Research Center, Animal Physiology Research Unit, 950 College Station Road, Athens, GA 30605 2720, USA
Gen Comp Endocrinol 133:61-70. 2003..These studies suggest that restricted adipogenesis in the pig fetus is attributable to limited DEX induced PPARgamma expression... - A method to establish co-cultures of myotubes and preadipocytes from collagenase digested neonatal pig semitendinosus musclesG J Hausman
Animal Physiology Research Unit, ARS, USDA Richard B Russell Agricultural Research Center, Athens, GA 30605 2720, USA
J Anim Sci 83:1010-6. 2005..For example, DEX did not alter myogenesis (i.e., 11 +/- 3 vs. 11 +/- 4 myotubes per unit area for control and DEX-treated cultures, respectively), but it has been shown to markedly increase preadipocyte number in muscle SV cell cultures... - Energy metabolism and leptin: effects on neuroendocrine regulation of reproduction in the gilt and sowC R Barb
USDA ARS, Richard B Russell Agriculture Research Center, University of Georgia, Athens, GA 30604, USA
Reprod Domest Anim 43:324-30. 2008..Thus, leptin appears to be an important link between metabolic status, the neuroendocrine axis and subsequent fertility in the gilt and sow... - A comparison of thiazolidinedione-induced adipogenesis and myogenesis in stromal-vascular cells from subcutaneous adipose tissue or semitendinosus muscle of postnatal pigsS P Poulos
Animal Physiology Research Unit, Richard B. Russell Agricultural Research Center, USDA-ARS, Athens, GA 30605-2720, USA
J Anim Sci 84:1076-82. 2006..These results suggest that regulation of intramuscular adipogenesis differs from that of subcutaneous adipogenesis... - Board-invited review: the biology and regulation of preadipocytes and adipocytes in meat animalsG J Hausman
USDA ARS, Richard B Russell Agricultural Research Station, Athens, GA 30604, USA
J Anim Sci 87:1218-46. 2009..Hence, this review is focused on current knowledge about the biology and regulation of the important cells of adipose tissue: preadipocytes and adipocytes... - Leptin: a metabolic signal affecting central regulation of reproduction in the pigC R Barb
USDA ARS, Animal Physiology Research Unit, Russell Research Center, P O Box 5677, Athens, GA 30604, USA
Domest Anim Endocrinol 29:186-92. 2005.... - Pre- and postnatal dietary conjugated linoleic acid alters adipose development, body weight gain and body composition in Sprague-Dawley ratsS P Poulos
Department of Foods and Nutrition, The University of Georgia, Athens, GA 30602, USA
J Nutr 131:2722-31. 2001..This response was due to differences in cell size rather than number. Response to CLA treatment may depend on the sex and age of the animal as well as duration of feeding... - Regulation of adipose cell development in uteroR J Martin
Department of Foods and Nutrition, University of Georgia and Animal Physiology, USDA Russell Research Center, Athens, Georgia 30602, USA
Proc Soc Exp Biol Med 219:200-10. 1998.... - Adipose tissue angiogenesisG J Hausman
USDA ARS, Richard B Russell Agricultural Research Center, Animal Physiology Research Unit, Athens, GA 30605 2720, USA
J Anim Sci 82:925-34. 2004..Finally, several studies including a study of mice treated with antiangiogenic factors indicate that adipose tissue accretion can be controlled through the vasculature per se... - Luteinizing hormone secretion as influenced by age and estradiol in the prepubertal giltC R Barb
USDA ARS, Poultry Processing and Swine Physiology Research Unit, Russell Research Center, P O Box 5677, Athens, GA 30604 5677, USA
Anim Reprod Sci 122:324-7. 2010..These results demonstrate an age related reduction in the sensitivity to the negative feedback action of estradiol on LH secretion and support the idea that the gilt conforms to the gonadostat hypothesis... - Gene expression profiling in developing pig adipose tissue: non-secreted regulatory proteinsG J Hausman
1USDA ARS, Russell Agricultural Research Center, Athens, GA 30604, USA
Animal 5:1071-81. 2011..Negative associations between expression of some regulatory factors and leptin gene expression indicated that local leptin may decrease or antagonize adipogenesis... - Secretion of insulin-like growth factor (IGF)-I and -II and IGF binding proteins (IGFBPs) in fetal stromal-vascular (S-V) cell cultures obtained before and after the onset of adipogenesis in vivoG J Hausman
USDA-ARS, R.B. Russell Agricultural Research Center, Animal Physiology Research Unit, Athens, GA 30604-5677, USA
Growth Dev Aging 66:11-26. 2002.... - Insulin-like growth factor-I feedback regulation of growth hormone and luteinizing hormone secretion in the pig: evidence for a pituitary site of actionC R Barb
1USDA ARS, Russell Research Center, PO Box 5677, Athens, GA 30604, USA
Animal 3:844-9. 2009..Further examination of the role of IGF-I on GH and LH secretion is needed to understand the inhibitory and stimulatory action of IGF-I on GH and LH secretion... - Influence of the pituitary on lipolysis and lipogenesis in fetal pig adipose tissueD B Hausman
University of Georgia, Athens
Horm Metab Res 25:17-20. 1993..6 fold by hypophysectomy. These results demonstrate the necessity of a functioning pituitary in the normal regulation of fatty acid synthesis and receptor-mediated lipolytic response in developing fetal adipose tissue... - Tumor necrosis factor-alpha binding in porcine primary stromal-vascular cell culturesY D Tchoukalova
University of Georgia, Athens 30602, USA
In Vitro Cell Dev Biol Anim 37:303-9. 2001..Also, it indicated the additional formation of smaller oligomers from both types of soluble receptors suggesting higher affinity of larger multimers for 125I-TNFalpha... - Adipocyte insensitivity to insulin in growth hormone-transgenic miceX L Chen
Diabetes Branch, NIDDK, National Institutes of Health, Bethesda, Maryland, USA
Biochem Biophys Res Commun 283:933-7. 2001..Our results suggest that increased expression of GH reduces adipogenesis by inducing adipocyte resistance to the adipogenic effect of insulin... - Analysis of a 762-bp proximal leptin promoter to drive and control regulation of transgene expression of growth hormone receptor in miceX L Chen
Animal and Dairy Science Department, The University of Georgia, USA
Biochem Biophys Res Commun 262:187-92. 1999.... - Mature adipocytes may be a source of stem cells for tissue engineeringM E Fernyhough
Department of Animal Sciences, Washington State University, P O Box 646310, Pullman, WA 99164, USA
Biochem Biophys Res Commun 368:455-7. 2008..Knowledge of these cells may also prove beneficial in cell-based therapies for tissue repair, regeneration, or engineering... - Gaining a solid grip on adipogenesisM E Fernyhough
Muscle Biology Laboratory, Washington State University, Department of Animal Sciences, 139 Clark Hall, Pullman, WA 99164, USA
Tissue Cell 37:335-8. 2005..Research has suggested that mature fat cells may dedifferentiate to form proliferative-competent fat cell precursors. Knowledge of the dedifferentiation process will allow us to gain a solid grip on adipogenesis...