Genomes and Genes
Shirley M Halling
Affiliation: Agricultural Research Service
- Evidence for lateral transfer to Brucellae: characterization of a locus with a Tn-like element (Tn2020)Shirley M Halling
Bacterial Diseases of Livestock Unit, National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, P O Box 70, Ames, IA 50010, USA
Biochim Biophys Acta 1574:109-16. 2002..The locus is lower in G+C content from that of the genome. These data suggest that lateral transfer of genetic material has occurred...
- Molecular targets for rapid identification of Brucella sppVladyslava G Ratushna
Department of Computer Science, College of Information Technology, University of North Carolina at Charlotte, Charlotte, NC 28223, USA
BMC Microbiol 6:13. 2006..We then screened a set of differentiating genes against classical Brucella biovars and showed the applicability of these regions in the design of diagnostic tests...
- Intrinsic and selected resistance to antibiotics binding the ribosome: analyses of Brucella 23S rrn, L4, L22, EF-Tu1, EF-Tu2, efflux and phylogenetic implicationsShirley M Halling
Bacterial Diseases of Livestock Research Unit, National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, 2300 Dayton Avenue, Ames, IA 50010, USA
BMC Microbiol 6:84. 2006..Neither the differential susceptibility nor its basis has been rigorously studied. Differences found among other conserved ribosomal loci could further define the relationships among the classical Brucella spp...
- Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suisShirley M Halling
Bacterial Diseases of Livestock Unit, NADC, ARS, USDA, 2300 Dayton Ave, Ames, IA 50010, USA
J Bacteriol 187:2715-26. 2005..melitensis than B. suis. The complete genomic sequence of B. abortus provides an important resource for further investigations into determinants of the pathogenicity and virulence phenotypes of these bacteria...
- Paradigm shifts in vaccine development: lessons learned about antigenicity, pathogenicity and virulence of BrucellaeShirley M Halling
Bacterial Diseases of Livestock Unit, National Animal Disease Center, P O Box 70, Ames, IA 50010, USA
Vet Microbiol 90:545-52. 2002..Studies at NADC and other brucellosis laboratories showed that antigenicity was not a predictor of the effectiveness of a protein as a subunit vaccine...
- Simple device to deliver beads to 96-well plates for rapid resuspension of bacterial pelletsShirley M Halling
National Animal Disease Laboratory/ARS/USDA, Ames, IA 50010, USA
Biotechniques 33:480, 482. 2002
- Diagnostic characterization of a feral swine herd enzootically infected with BrucellaWilliam C Stoffregen
Bacterial Diseases of Livestock Research Unit, National Animal Disease Center, US Department of Agriculture, Ames, IA 50010, USA
J Vet Diagn Invest 19:227-37. 2007..This is the first report of an apparent enzootic Brucella abortus infection in a feral swine herd suggesting that feral swine may serve as a reservoir of infection for Brucella abortus as well as Brucella suis for domestic livestock...
- Effect of polymyxin B and environmental conditions on isolation of Brucella species and the vaccine strain RB51Allen E Jensen
National Animal Disease Center, United States Department of Agriculture, Ames, IA 50010, USA
Comp Immunol Microbiol Infect Dis 33:121-31. 2010..Our observations extend basic knowledge of the differential resistance of Brucella to polymyxins...
- Defensin susceptibility and colonization in the mouse model of AJ100, a polymyxin B-resistant, Brucella abortus RB51 isolateShirley M Halling
Bacterial Diseases of Livestock Unit, National Animal Disease Center, Agricultural Research Service, US Department of Agriculture, 2300 Dayton Avenue North, PO Box 70, Ames, IA 50010, USA
Curr Microbiol 56:274-8. 2008....
- Brucella 'HOOF-Prints': strain typing by multi-locus analysis of variable number tandem repeats (VNTRs)Betsy J Bricker
United States Department of Agriculture, Agricultural Research Service, National Animal Disease Center, 2300 Dayton Rd, Ames, IA 50010, USA
BMC Microbiol 3:15. 2003..Recently, hypervariability among short tandem repeat sequences has been exploited for strain-typing of several bacterial pathogens...
- The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbiontsIan T Paulsen
The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
Proc Natl Acad Sci U S A 99:13148-53. 2002..A limited repertoire of genes homologous to known bacterial virulence factors were identified...